Abstract：
:Thirty-eight hepatitis B virus (HBV) carriers, AgHBs and anti-HBe positive, with histologic diagnosis of chronic hepatitis have been periodically revised for three years. Three of them were homosexuals. Fourteen patients presented reactivation of viral replication characterized by the appearance in serum of HBV-DNA and an increase in transaminase levels. Only 7/27 (26%) presented spontaneous reactivation in contrast with 7/11 (64%) patients who had been treated with immunosuppression (p less than 0.05). Furthermore, in 3 cases free AgHBe was temporarily detected during reactivation. Histologic diagnosis and Knodell index were basically similar in reactivated patients and the rest. However, those who presented spontaneous reactivation presented a higher number of AgHB positive cells in liver tissue, both in nucleus and cytoplasm, than patients without reactivation, although, there were no significant differences in relation to the type of reactivation. In summary, this study suggests that immunosuppressants should not be given to HBV carriers with anti-HBe, since this would facilitate the reactivation of viral replication.
journal_name
Rev Clin Espjournal_title
Revista clinica espanolaauthors
Porres JC,Carreño V,Moreno A,Bartolomé FJsubject
Has Abstractpub_date
1991-06-01 00:00:00pages
68-72issue
2eissn
0014-2565issn
1578-1860journal_volume
189pub_type
杂志文章abstract：:A retrospective study is presented of 19 patients who suffered Hypercortisolism who were examined by adrenal gammagraphy, echography, and CT scan in order to evaluate the usefulness of gammagraphy in the diagnostic approximation of this pathology. The gammagraphy findings had an excellent correlation with anatomopatho...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1991-04-01 00:00:00
abstract：OBJECTIVES:To assess the routine indication of chest roentgenogram after thoracentesis in function of iatrogenic pneumothorax causation, following a procedure protocol. PATIENTS AND METHODS:Prospective study of 104 consecutive thoracentesis procedures performed in 76 patients. The procedure was protocolized and after ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13044921
更新日期：2003-03-01 00:00:00
abstract：:Type 2 diabetes mellitus is a major health problem with high prevalence, morbidity and mortality, and its medical treatment is growing in complexity due to patients' diverse clinical conditions. This article presents a consensus document by the Diabetes, Obesity and Nutrition Group of the Spanish Society of Internal M...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2020.06.005
更新日期：2020-07-13 00:00:00
abstract：BACKGROUND:In recent years, there has been an increase of drugs poisoning cases seen in the Emergency Department. This study has aimed to evaluate the characteristics of these cases in the Ramón and Cajal Hospital in Madrid. MATERIALS AND METHODS:A descriptive analysis about the drug poisonings diagnosed in 2004 was p...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13127603
更新日期：2008-10-01 00:00:00
abstract：:The clinical characteristics of systolic and diastolic hypertension in 75 and of systolic hypertension in 50 elderly patients have been studied and the results have been compared to those obtained in 23 normotense elderly controls and 500 young patients with essential hypertension. A greater incidence in cardiovascula...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1989-06-01 00:00:00
abstract：:Knowledge of cardiovascular disease is advancing at a vertiginous pace. Cardiology has always been one of the most scientifically dynamic specialties. Indeed, no other medical specialty presents such a large number of randomized studies aiming to determine the efficacy of distinct therapeutic interventions each year. ...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：10.1016/S0014-2565(10)70002-3
更新日期：2010-09-01 00:00:00
abstract：BACKGROUND:High concentrations of total and LDL-cholesterol and low concentrations of HDL-cholesterol are related to morbidity and mortality due to cardiovascular diseases. In this study, lipid concentration, prevalence of hypercholesterolemia and the association between hypercholesterolemia and other cardiovascular ri...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1993-06-01 00:00:00
abstract：:Laughter is associated to many physiological and psychological benefits. Although women laugh more than men do, the daily frequency of laughter does not seem to differ. Laughter in all its forms and manifestations is an indicator of family vitality and healthy couples. Laughter is very attractive at the interpersonal ...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：10.1016/j.rce.2010.10.013
更新日期：2011-07-01 00:00:00
abstract：OBJECTIVES:To determine which social and individual factors may predict adherence to medication in patients with more than two chronic symptomatic diseases (polypathological patients) under polypharmacy. METHODS:Cross-sectional observational study. In a primary care area assigned to our teaching hospital 265 patients ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2009.11.015
更新日期：2010-05-01 00:00:00
abstract：:After recognizing smoking habit as a relevant problem in our media, the complex implications of this type of lifestyle are commented. After revising the main obstacles for achieving primary health care preventive measures not only for the patient, who frequently looks for a "treatment", but also for the professional w...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：
更新日期：1989-03-01 00:00:00
abstract：:The aim or our study was to evaluate the main clinical and etiological features or primary acute pericarditis with severe pericardial effusion without cardiac tamponade. Our experience included 35 patients with this problem diagnosed in the last 5 years. Patients with a previous potential etiology for acute pericardit...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/s0014-2565(06)72744-8
更新日期：2006-03-01 00:00:00
abstract：:Painful legs and moving toes syndrome is a rare medical picture characterized by involuntary movements of the toes or the whole foot and pain in lower limbs. However, this must be kept in mind due to its association with other diseases and its possibility of being the first symptom. Spinal cord and cauda equina diseas...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：10.1157/13102318
更新日期：2007-05-01 00:00:00
abstract：:Inflammatory pseudotumor (IP) is a rare pathological entity. Although, the pulmonary affection is the most frequent, any other organ can be involved. Its etiopathology is unknown. The disease is considered as a reactive process constituted by chronic inflammatory elements and a benign behavior. The lack of a specific ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1991-12-01 00:00:00
abstract：:Although the number of elderly needing health care is increasing in Spain, geriatric patients do not receive enough attention or support when compared to that given in other countries. When the elderly get sick they present peculiar and special problems which should be attended following their needs. Because in hospit...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1989-03-01 00:00:00
abstract：:The purpose of this study was to review the epidemiological aspects and the characteristics of the thyroid disfunction produced by amiodarone in Catalonia, an area with type I endemic goiter. For this purpose, three groups of patients have been studied: 1) 102 patients with prolonged amiodarone treatment, out of whom ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1991-02-01 00:00:00
abstract：BACKGROUND:There are no simple and validated instruments for evaluating the training of specialists. OBJECTIVES:To analyze the reliability and validity of a computerized self-assessment method to quantify the acquisition of medical competences during the Internal Medicine residency program. METHODS:All residents of o...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2012.04.004
更新日期：2012-12-01 00:00:00
abstract：:We have studied a group of 33 (27 female and 6 male) patients suffering pure essential arterial hypertension, with a mean age of 54.06 years, and who received a daily monodose of chlortalidone. Arterial pressure, blood viscosity at different shearing levels, as well as those parameters capable of modifying this viscos...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1990-09-01 00:00:00
abstract：OBJECTIVE:To demonstrate the validity of diurnal polysomnography for the diagnosis of obstructive sleep apnea syndrome (OSAS). METHODS:Twenty-five patients with suspect of OSAS were studied with two serial polysomnographic recordings: one during nighttime-nocturnal polysomnography (NPLS) and then a second polysomnogra...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1998-06-01 00:00:00
abstract：:Anisakis simplex is a nematode which parasitizes mainly fish and cephalopods and accidentally human beings after ingestion. Apart from the different digestive syndromes, this organism has recently been involved as cause of IgE-mediated allergic reactions of variable degree (urticaria to severe angioedema). In this rep...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1998-09-01 00:00:00
abstract：:Clostridium difficile is the leading cause of infectious nosocomial diarrhea in the elderly. It may cause colitis of variable severity and extraintestinal involvement. Hand transmission is the most important, and it is related to prolonged antibiotic therapies in elderly patients with severe baseline disease. Diagnosi...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13100203
更新日期：2007-02-01 00:00:00
abstract：:Study of the human proteome has given rise to the appearance of abundant and increasing scientific literature. This has resulted in the proposal to use proteomic techniques in the management of some diseases and the suggestion of its future use in clinical laboratories. In order to identify which proteomic techniques ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13107947
更新日期：2007-07-01 00:00:00
abstract：OBJECTIVE:To analyze the different therapeutic attitudes towards patients with arterial hypertension (AH) or white coat hypertension (WCH). DESIGN:Longitudinal, retrospective study after performing a 24 h ambulatory blood pressure monitoring of ABPM. SETTING:Urban health center. PATIENTS:Eighty-six patients aged ove...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：2001-04-01 00:00:00
abstract：BACKGROUND:Nosocomial infection (NI) is associated with an increase in resource consumption. The estimation of extra costs attributable to NI in a group of patients with catheter-related bacteremia (CRB) was the objective of the present study. METHODS:A matched case-control, study was conducted in a cohort population....
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1998-10-01 00:00:00
abstract：OBJECTIVE:To report the clinical and epidemiologic characteristics of 19 patients diagnosed of tularemia at our hospital following an epidemic outbreak occurred in our health area. METHODS:Retrospective analysis of clinical records of patients admitted to our hospital who were examined at the Infectious Diseases Clini...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/s0014-2565(01)70854-5
更新日期：2001-07-01 00:00:00
abstract：:Six patients with severe and complicated falciparum malaria (6.7 +/- 2.7 WHO criteria) were admitted to our Intensive Care Unit. All patients acquired the disease while travelling in tropical Africa without appropriate chemoprophylaxis. The clinical manifestations included hyperpyrexia (all patients), chills (4), swea...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1998-08-01 00:00:00
abstract：:Pancreas transplantation offers the possibility of preventing the development and progression of diabetic lesions by adequate control of hydrocarbon metabolism. Moreover, the diabetic patient is freed from dietary and physical restrictions, as well as from insulin treatment. However, this is achieved at the expense of...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：
更新日期：1989-07-01 00:00:00
abstract：:Three new cases of diffuse pulmonary lymphangioleiomyomatosis are presented. Case number 1 is a female patient who presented repeated pneumotorax and dyspnea without evidence by CT scan and gynecological ultrasound of extrathoracic lesions. This patient did not respond to medroxiprogesterone and died 5 years after the...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：
更新日期：1990-04-01 00:00:00
abstract：OBJECTIVES:We evaluated the effect of an intervention on certain quality indicators employed for improving the treatment of hospital hyperglycemia. MATERIAL AND METHODS:A multicenter cross-sectional study was conducted on patients with hyperglycemia hospitalized in the internal medicine departments of 44 hospitals eva...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2016.05.006
更新日期：2016-10-01 00:00:00
abstract：OBJECTIVE:To prospectively and comparatively study the usefulness of urine (viruria) and blood (antigenemia pp65 and culture) (viremia) for the diagnosis of cytomegalovirus (CMV) infection in renal transplant (RT) recipients. MATERIAL AND METHODS:All RT recipients at our hospital were studied from January 1995 to Dece...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：:The socio-economic cost of human brucellosis is analyzed. One hundred and seven patients are included in this study, 75 males (70.09%) and 32 females (29.91), diagnosed of brucellosis in the Internal Medicine Department of the Regional Hospital "Carlos Haya" in Málaga from the 1st of October 1984 to the 31st of Decemb...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1989-12-01 00:00:00
