[Evaluation of alpha 1-antitrypsin phenotypes in Castilla-León: study of a population of newborn infants].

Abstract:

:We have screened a population of newborn babies without any previous apparent pathology in order to discover the distribution of alpha 1-anti-trypsin phenotypes (AAT) in our community. The research has been done on 457 babies born in the province of Valladolid, determining the plasma levels of AAT and the corresponding phenotype. AAT quantification was done by nephelometry, and the phenotypic study was done by the technique described by Jeppsson. It has been possible to identify 8 different phenotypes, PIM being the one that had the highest incidence rate (72.42%), followed by PIMS (19.69%). In relation to the serum levels of AAT, the highest values were found for PIM (220 +/- 60 mg/dl) and the lowest for PIZ (43 +/- 2 mg/dl). Finally, the results obtained by our laboratory are compared with those of other authors.

journal_name

Rev Clin Esp

journal_title

Revista clinica espanola

authors

Andrés Puertas MJ,Arranz Peña ML

subject

Has Abstract

pub_date

1989-02-01 00:00:00

pages

106-8

issue

2

eissn

0014-2565

issn

1578-1860

journal_volume

184

pub_type

杂志文章
  • [Geriatric assistance: an unresolved health problem].

    abstract::Although the number of elderly needing health care is increasing in Spain, geriatric patients do not receive enough attention or support when compared to that given in other countries. When the elderly get sick they present peculiar and special problems which should be attended following their needs. Because in hospit...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:

    authors: Caballero García JC

    更新日期:1989-03-01 00:00:00

  • [Improvement in diastolic function in hypertensive patients with left ventricular hypertrophy with inhibitors of the angiotensin converting enzyme].

    abstract::An open and multicentric study was conducted with 66 patients with mild to severe diastolic arterial hypertension and echocardiographic left ventricular hypertrophy, the evolution of diastolic function, by means of doppler transmitral flow echocardiography, under treatment with ramipril, an angiotensin converting enzy...

    journal_title:Revista clinica espanola

    pub_type: 临床试验,杂志文章,多中心研究

    doi:

    authors: Sagastagoitia JD,Morillas M,Martínez A,Lage E,Pallarés C,Ugartemendía C,Asín E,Barrios V,Julia J,Sánchez P,Calvo C,González J,Piña C,García-Barbal J,Arnau C

    更新日期:1998-01-01 00:00:00

  • [Hereditary hemorrhagic telangiectasia at an internal medicine service: study of 12 patients].

    abstract::Hereditary hemorrhagic telangiectasia (HHT) is a hereditary dominant autosoma clinical entity characterized by repeated hemorrhages (being epistaxis the more frequent) and telangiectasia in skin, mucosa and internal organs. Incidence in Europe is 1,2 per 100,000 pop. We discuss the experience of an Internal Medicine D...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:

    authors: Cabañes Argudo M,Villar Grimalt A,Puche Azorín P,Franco Serrano J,Brotons Brotons B

    更新日期:1992-10-01 00:00:00

  • [A clinical study of human leptospirosis. Apropos 215 cases].

    abstract::215 cases diagnosed of human leptospirosis in the Camagüey Province, Cuba, are studied, for the period between 1986 and 1990. The clinical and epidemiological features are studied, together with the anatomopathological study of the decreased. The most frequent complications and the treatment employed, including prophy...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:

    authors: Roura Carrasco J,Pila Pérez R,Caveda Estela O,Pila Peláez R

    更新日期:1992-05-01 00:00:00

  • [Upper limb deep venous thrombosis. Risk factors, outcome, and posthrombotic syndrome].

    abstract:OBJECTIVE:Our objective was that of describing a series of episodes of upper limb deep venous thrombosis, with special emphasis on the incidence of posthrombotic syndrome and its impact in the quality of life of the patients. METHODS:33 episodes (29 patients) of upper limb deep venous thrombosis were studied, between ...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:10.1157/13070751

    authors: Gargallo Maicas C,Todolí Parra JA,Romera Barroso B,Suárez Alvarez L,Calabuig Muñoz E,Saro Pérez E,Bonora Tamarit V,Calabuig Alborch JR

    更新日期:2005-01-01 00:00:00

  • [The presence of oligoclonal bands in the cerebrospinal fluid in various neurologic diseases].

    abstract::The polyacrylamide gel electrophoresis of spinal fluid from 488 patients suffering neurological diseases and from a control group are reviewed. One hundred and eleven cases (22.7%) showed oligoclonal bands (OB). The highest percentage of OB appeared in the group of patients with definite multiple sclerosis (84%), foll...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:

    authors: Coret F,Vílchez JJ,Enguídanos MJ,López-Arlandis J,Fernández-Izquierdo S

    更新日期:1989-10-01 00:00:00

  • [Usefulness of urine and blood cultures for diagnosing cytomegalovirus infection in the kidney transplant recipient].

    abstract:OBJECTIVE:To prospectively and comparatively study the usefulness of urine (viruria) and blood (antigenemia pp65 and culture) (viremia) for the diagnosis of cytomegalovirus (CMV) infection in renal transplant (RT) recipients. MATERIAL AND METHODS:All RT recipients at our hospital were studied from January 1995 to Dece...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:

    authors: Reina Prieto J,Bestard Palmer X,Saurina Gomila J,Gascó Company J,Fernández-Baca Gutiérrez del Alamo V,Munar Roca M

    更新日期:1998-01-01 00:00:00

  • [Tularemia outbreak in the province of Cuenca associated with crab handling].

    abstract:OBJECTIVE:To report the clinical and epidemiologic characteristics of 19 patients diagnosed of tularemia at our hospital following an epidemic outbreak occurred in our health area. METHODS:Retrospective analysis of clinical records of patients admitted to our hospital who were examined at the Infectious Diseases Clini...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:10.1016/s0014-2565(01)70854-5

    authors: Díaz de Tuesta AM,Chow-Quan,Geijo Martínez MP,Dimas Núñez J,Díaz de Tuesta FJ,Herranz CR,Val Pérez E

    更新日期:2001-07-01 00:00:00

  • [Report of the editors, 2011].

    abstract::The editors of Revista Clínica Española (Rev Clin Esp) inform on their editorial activity during the last 12 months (November 2010 to October 2011): (a) Objectives and attainments during 2011, (b) editorial activity, and (c) objectives for 2012. In 2011 we have updated the editorial algorithm (revision by the responsi...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:10.1016/j.rce.2011.11.004

    authors: García Puig J,Gaspar Alonso-Vega G,Ríos Blanco JJ

    更新日期:2012-01-01 00:00:00

  • [Differential characteristics of primary acute pericarditis and severe pericardial effusion without tamponade].

    abstract::The aim or our study was to evaluate the main clinical and etiological features or primary acute pericarditis with severe pericardial effusion without cardiac tamponade. Our experience included 35 patients with this problem diagnosed in the last 5 years. Patients with a previous potential etiology for acute pericardit...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:10.1016/s0014-2565(06)72744-8

    authors: Siles Rubio JR,Anguita Sánchez MP,Ruiz de Castroviejo del Campo J,Castillo Domínguez JC

    更新日期:2006-03-01 00:00:00

  • Analysis of patients shared in consultations of internal medicine and other medical specialties.

    abstract:BACKGROUND AND OBJECTIVE:The aging population is resulting in an increasing number of patients with multiple diseases that require treatment by various specialties. We examined the evolution of consultations and of the percentage of patients treated by several medical specialties. METHODS:We analysed internal medicine...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:10.1016/j.rce.2019.03.005

    authors: Jiménez-Puente A,Martín-Escalante MD,Martos-Pérez F,García-Alegría J

    更新日期:2019-12-01 00:00:00

  • Clinical ultrasonography in systemic autoimmune diseases.

    abstract::Clinical ultrasonography should be considered a complementary examination that can change clinical practice, as well as a tool to add to the medical history. Systemic autoimmune diseases (SAD) can involve numerous structures and organs. Ultrasonography has broad applied utility in detecting complications such as the p...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:10.1016/j.rce.2019.07.014

    authors: Serralta San Martín G,Canora Lebrato J,en representación del Grupo de Trabajo de Ecografía Clínica y del Grupo de Trabajo de Enfermedades Autoinmunes Sistémicas de la Sociedad Española de Medicina Interna.

    更新日期:2020-01-01 00:00:00

  • Acute, subacute and chronic mountain sickness.

    abstract::More than 100 million people ascend to high mountainous areas worldwide every year. At nonextreme altitudes (<5500 m), 10-85% of these individuals are affected by acute mountain sickness, the most common disease induced by mild-moderate hypobaric hypoxia. Approximately 140 million individuals live permanently at heigh...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章,评审

    doi:10.1016/j.rce.2019.12.013

    authors: Garrido E,Botella de Maglia J,Castillo O

    更新日期:2020-03-17 00:00:00

  • [Socioeconomic effects of human brucellosis].

    abstract::The socio-economic cost of human brucellosis is analyzed. One hundred and seven patients are included in this study, 75 males (70.09%) and 32 females (29.91), diagnosed of brucellosis in the Internal Medicine Department of the Regional Hospital "Carlos Haya" in Málaga from the 1st of October 1984 to the 31st of Decemb...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:

    authors: Colmenero Castillo JD,Cabrera Franquelo FP,Hernández Márquez S,Reguera Iglesias JM,Pinedo Sánchez A,Castillo Clavero AM

    更新日期:1989-12-01 00:00:00

  • [Phosphodiesterase-4 inhibitors: roflumilast].

    abstract::Chronic obstructive pulmonary disease (COPD) encompasses a group of diseases characterized by chronic airway obstruction. This broad diagnostic umbrella includes several clinical phenotypes that overlap and respond differently to each type of therapeutic intervention. Roflumilast is a drug belonging to the new therape...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章,评审

    doi:10.1016/S0014-2565(11)70008-X

    authors: Izquierdo Alonso JL

    更新日期:2011-03-01 00:00:00

  • [Stroke in the hands of the internist. Cardiovascular risk factors].

    abstract:INTRODUCTION:This study has aimed to describe cardiovascular risk factors (CVRF) associated to stroke and their detection and monitoring during the acute episode and the recommendations on hospital discharge. The hypothesis was to check if the integral care of the internist improved the care to these patients. MATERIA...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:10.1157/13124313

    authors: Sanclemente Ansó C,Pedragosa Vall A,Rovira Pujol E,Vigil Martín D

    更新日期:2008-07-01 00:00:00

  • [Utilization of antibiotics in a hospital emergency department. Quality of prescription].

    abstract:OBJECTIVES:To know the frequency of antibiotic prescription, the conditions that motivate their usage, and to evaluate the quality of such therapies in a hospital emergency department (HED). METHODS:Retrospective study of 2,677 patients attended at a HED for a one-month period including those who had antibiotics presc...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:

    authors: Laguna P,Moya MS,García F,Salgado R,Calabrese S

    更新日期:1996-07-01 00:00:00

  • Have the Government's prescription algorithm and the 2013 American College of Cardiology/American Heart Association guidelines for managing dyslipidaemia influenced the management of dyslipidaemia? The MEJORALO-CV Project.

    abstract:OBJECTIVE:To determine the management of dyslipidaemia in primary care after the publication of the American College of Cardiology/American Heart Association (ACC/AHA) 2013 guidelines and Valencian government's algorithm. METHOD:We conducted a cross-sectional descriptive study that employed a survey of primary care ph...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:10.1016/j.rce.2019.08.006

    authors: Giner Galvañ V,Bonig Trigueros I,Fácila Rubio L,Morillas Blasco P,Martínez Hervás S,Pascual Fuster V,Valls Roca F,Soler Portmann C,Tamarit García JJ,Pallarés Carratalá V,en representación del Grupo de Trabajo MEJORA-LO CV.,Componen

    更新日期:2020-01-01 00:00:00

  • [Peritoneal mesothelioma and complete auriculo-ventricular block as late complications in Hodgkin's disease].

    abstract::A patient who had been successfully treated of Hodgkin's disease (nodular sclerotic type) with mediastinal radiotherapy and polychemotherapy, suffered an acute pericarditis immediately after radiotherapy and a complete atrial-ventricular block 14 years later. Five years later she presented refractory hemorrhagic perit...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:

    authors: Ladero Quesada JM,Amarillas Sánchez L,Furió Bacete V,Laredo Velasco L

    更新日期:1991-10-01 00:00:00

  • [Dehydroepiandrosterone sulfate and lipids in acute myocardial infarct].

    abstract::To establish the possible relationship between acute myocardial infarction (AMI) and dehydroepiandrosterone-sulfate (DHEA-S) in a group of 15 patients with AMI, blood levels of DHEA-S and certain lipids (total cholesterol, LDL-cholesterol, HDL-cholesterol and triglycerides) were determined at admission in the hospital...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:

    authors: Ruiz Salmerón RJ,del Arbol JL,Torrededia J,Raya Muñoz J,López Luque A,Rico Irlés J,Ruiz Requena ME,Bolaños J

    更新日期:1992-05-01 00:00:00

  • [Fibromyalgia and its diagnosis].

    abstract::Fibromyalgia or fibromyalgic syndrome (FMS) is a clinical picture of unknown origin that is characterized by generalized, incapacitating and chronic pain together with the demonstration in the physical examination of previously defined points in which moderate pressure causes pain, called fibromyalgia tender points (F...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:10.1157/13077119

    authors: Andreu JL,Sanz J

    更新日期:2005-07-01 00:00:00

  • [Clinical characteristics of arterial hypertension in the elderly].

    abstract::The clinical characteristics of systolic and diastolic hypertension in 75 and of systolic hypertension in 50 elderly patients have been studied and the results have been compared to those obtained in 23 normotense elderly controls and 500 young patients with essential hypertension. A greater incidence in cardiovascula...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:

    authors: Puras A,Alcázar JM,Miranda B,Oliet A,Rodicio JL,Ruilope LM

    更新日期:1989-06-01 00:00:00

  • [Decisions and therapeutic attitudes for patients with white coat hypertension].

    abstract:OBJECTIVE:To analyze the different therapeutic attitudes towards patients with arterial hypertension (AH) or white coat hypertension (WCH). DESIGN:Longitudinal, retrospective study after performing a 24 h ambulatory blood pressure monitoring of ABPM. SETTING:Urban health center. PATIENTS:Eighty-six patients aged ove...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:

    authors: Vinyoles Bargalló E,Garaikoetxea Iturriria A,Ibernón López M,Sancho Muñoz S,Díaz de Sarralde B,de la Figuera von Wichmann M

    更新日期:2001-04-01 00:00:00

  • [Complications of liver transplant in intensive care. Experience in 130 cases].

    abstract::Liver transplant is the first therapeutic choice in most of the advanced liver diseases. Nevertheless, its performance originates a number of complications derived from: a) conservation techniques of the organ (in our study a prolonged time of hot ischemia was significantly associated with); b) surgery (all patients w...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:

    authors: Cisneros Alonso C,Montero Castillo A,Moreno González E,García García I,Guillén Ramírez F,García Fuentes C

    更新日期:1991-10-01 00:00:00

  • [Medulloblastoma in the adult: presentation of a new case].

    abstract::A case of hemispheric medulloblastoma of cerebellum in a 22 male patient is presented. The patient complained of headache and an intracranial hypertension syndrome progressively appeared. Diagnosis was established by CT scan. Treatment consisted of radical surgery associated to radiotherapy and chemotherapy. Present s...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:

    authors: Díez Manglano J,Callau Barrio MP,Hermosilla Cabrerizo T,Pérez Calvo JI,Tres Sánchez A,Bueno Gómez J

    更新日期:1992-01-01 00:00:00

  • [Psychometric validation of translation to Spanish of the gastrointestinal symptoms rating scale (GSRS) and quality of life in reflux and dyspepsia (QOLRAD) in patients with gastroesophageal reflux disease].

    abstract:INTRODUCTION:Pyrosis symptoms and their impact on the quality of life related with health (QLRH) are frequently evaluated in clinical trials. When a questionnaire is translated into a language other than the original, it is necessary to have a linguistic validation, although this is not sufficient unless the psychometr...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:10.1016/s0014-2565(05)72651-5

    authors: Kulich KR,Piqué JM,Vegazo O,Jiménez J,Zapardiel J,Carlsson J,Wiklund I

    更新日期:2005-12-01 00:00:00

  • [Pulmonary aspiration puncture in the etiological diagnosis of pneumonias].

    abstract::In pneumonias, the short diagnostic results of non-invasive procedures lead frequently to use invasive techniques, among which we find pulmonary puncture aspiration (PPA). In this study, the profitability of PPA in the diagnosis of pneumonias is evaluated. One hundred and thirteen PPA were performed on 107 patients di...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:

    authors: Ayerbe R,Verano A,Capote F,Pachón J,Cuello JA,Segado A

    更新日期:1994-04-01 00:00:00

  • [Cellular immune response in tuberculosis: analysis of T-lymphocytes and their subsets, B-lymphocytes and natural cytotoxic cells in different tuberculosis states and body fluids].

    abstract:BACKGROUND:The immune response to Mycobacterium tuberculosis is primarily mediated by T lymphocytes. In this study an investigation was made of T lymphocytes and their subsets, B lymphocytes and natural cytotoxic cells (Natural Killer, NK) in blood and organic fluids in different tuberculosis conditions. METHODS:Patie...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:

    authors: Montes Santiago J,Gambón Deza F,Pacheco Carracedo M,Cerdá Mota T

    更新日期:1996-04-01 00:00:00

  • [Pancreatic changes associated with acute gastroenteritis].

    abstract::A retrospective study is discussed, in which the disorder of pancreatic enzymes in hospitalized patients because of an acute infectious gastroenteritis is analyzed. Of 30 cases, 15 showed a raise in lipase levels, being over 1,000 IU in five of them. There was no associated raise in amylase levels. Patients with high ...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:

    authors: Poza JJ,Amato E,Mentxaka B

    更新日期:1992-10-01 00:00:00

  • [Guide for the prevention and treatment of glucocorticoid-induced osteoporosis of the Spanish Society of Internal Medicine].

    abstract::Our objective has been to elaborate an updated Clinical Guide of the Spanish Society of Internal Medicine (SEMI) for the prevention and treatment of glucocorticoids-induced osteoporosis (GIO), identifying and measuring the grade of evidence that supports the given recommendations. For this, we reviewed studies perform...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章,实务指引

    doi:10.1157/13115006

    authors: Sosa Henríquez M,Díaz Curiel M,Díez Pérez A,Gómez Alonso C,González Macías J,Farrerons Minguella J,Filgueira Rubio J,Mellibovsky Saidler L,Nogués Solán X,Hernández Hernández D,Sociedad Española de Medicina Interna.

    更新日期:2008-01-01 00:00:00