Abstract：
:An open and multicentric study was conducted with 66 patients with mild to severe diastolic arterial hypertension and echocardiographic left ventricular hypertrophy, the evolution of diastolic function, by means of doppler transmitral flow echocardiography, under treatment with ramipril, an angiotensin converting enzyme inhibitor, at a dose of 2.5 and 5 mg/day, or combined with a diuretic, after three and six months of treatment. Despite not obtaining the tensional control in all patients, a decrease in the mass, both in absolute values and mass index, was obtained. This decrease was observed both in male and female patients from the first three months, which went on until the sixth month, thus suggesting an independent action of the hemodynamic load decrease for the obtention of this effect. There was also a change in the ventricular geometry with a displacement of patients from concentric enlargement to normal, remodelling and eccentric enlargement. The diastolic function improved both for the early and for the late maximal filling velocity, relationship between both, and deceleration time, although the time during which this improvement occurred was different for each parameter, thus indicating the different influence of the dynamic and structural factors on these parameters. No correlation was found between the improvement in diastolic function and hypertrophy regression. We can conclude that ramipril is useful for the control of the left ventricular hypertrophy and diastolic function, irrespective of arterial tension values.
journal_name
Rev Clin Espjournal_title
Revista clinica espanolaauthors
Sagastagoitia JD,Morillas M,Martínez A,Lage E,Pallarés C,Ugartemendía C,Asín E,Barrios V,Julia J,Sánchez P,Calvo C,González J,Piña C,García-Barbal J,Arnau Csubject
Has Abstractpub_date
1998-01-01 00:00:00pages
15-22issue
1eissn
0014-2565issn
1578-1860journal_volume
198pub_type
临床试验,杂志文章,多中心研究abstract：:Non insulin antidiabetic drugs are widely used in patients with type 2 diabetes. However, the drugs' effect in terms of reducing cardiovascular risk has been the subject of controversy. In 2008, based on the evidence of cardiovascular risk resulting from the use of a number of non insulin antidiabetic drugs, the US Fo...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2017.02.007
更新日期：2017-11-01 00:00:00
abstract：OBJECTIVES:To ascertain the correlation between the partial pressure of oxygen (PaO2) and oxyhaemoglobin saturation by pulse oximetry (SpO2) in patients who were admitted to the emergency department with suspected acute respiratory failure. MATERIAL AND METHODS:A prospective, observational multicentre study was conduc...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2017.08.006
更新日期：2017-12-01 00:00:00
abstract：OBJECTIVES:To evaluate the scientific output in Biomedicine and Health Sciences in Andalusia in the context of the published works on the national scientific output in the last few years. MATERIAL:Descriptive study with seven different information sources: a) final Report of the Experts Committee on Documentation from...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1996-09-01 00:00:00
abstract：:Given the increasing interest in Lyme borreliosis in our community, and the lack of epidemiological studies in our country, we have considered convenient to analyze the presence of anti-Borrelia burgdorferi antibodies in a group of workmen who we have considered at high risk since they carry out their everyday work in...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1990-10-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Burnout is a psychosocial syndrome caused by stressful working conditions and affects 30-60% of medical personnel. The aim of this study was to assess the burnout rate of Spanish internists and the factors related to its onset. MATERIAL AND METHODS:We conducted a survey of work conditions fol...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2019.10.009
更新日期：2020-01-01 00:00:00
abstract：:Antibodies (type IgG) against the A 60 antigen (Mycobacterium bovis, BCG) and an antigen of Mycobacterium tuberculosis were studied by ELISA in 79 patients with not tuberculous disease: 16 lung carcinoma, 16 hepatic cirrhosis and 47 patients with pulmonary disease. 59.5% and 50.6% of the patients showed antibodies aga...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1992-04-01 00:00:00
abstract：OBJECTIVES:Heart failure decompensation is the most common reason for hospitalization in persons over 65 years old. There is limited information on the prevalence of precipitating factors of heart failure decompensation in this population. In this study we prospectively examined the factors associated with decompensati...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2010.04.020
更新日期：2010-11-01 00:00:00
abstract：:Deep vein thrombosis (DVT) is part of the clinical spectrum of venous thromboembolism disease (VTE), whose estimated annual incidence rate is 1-2 episodes per 1000 individuals and represents the third leading cause of cardiovascular mortality in developed countries. Establishing an accurate diagnosis of DVT is essenti...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：10.1016/j.rce.2020.03.009
更新日期：2020-06-27 00:00:00
abstract：BACKGROUND:High concentrations of total and LDL-cholesterol and low concentrations of HDL-cholesterol are related to morbidity and mortality due to cardiovascular diseases. In this study, lipid concentration, prevalence of hypercholesterolemia and the association between hypercholesterolemia and other cardiovascular ri...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1993-06-01 00:00:00
abstract：:The contributions of Santiago Ramon y Cajal to Modern medicine are innumerable. This large scientist and humanist, a man ahead of his time, spoke for the first time such concepts as angiogenesis, which represents one of the most innovative fields for oncology today, in addition to conducting experimental research on t...
journal_title：Revista clinica espanola
pub_type： 传,历史文章,杂志文章
doi：10.1016/s0014-2565(08)76037-5
更新日期：2008-12-01 00:00:00
abstract：OBJECTIVE:To know the prevalence of adrenal insufficiency (AI) in our patients with acquired immunodeficiency syndrome (AIDS) and to compare the clinical manifestations with those reported in previous series in the literature. PATIENTS AND METHODS:Retrospective study with review of clinical records of patients with AI...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1998-02-01 00:00:00
abstract：:The presence of anti-HIV (human immunodeficiency virus) antibodies was determined in 325 subjects. The samples were taken from 138 convicts from Carabanchel and Ocaña I jail, 162 parenteral drug addicts (PDA) from a center for rehabilitation of drug addicts (CR), and from 14 family members and 11 stable couples of the...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1989-04-01 00:00:00
abstract：BACKGROUND:Usually, there is a physiological fall in nocturnal blood pressure among all individuals, both hypertensive and normotensive individuals. The lack of nocturnal blood pressure (BP) fall may be associated with the risk of developing cardiovascular complications in hypertensive patients. Cardiovascular and horm...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/s0014-2565(02)71048-5
更新日期：2002-05-01 00:00:00
abstract：:With the aim to analyze the prognostic value of anti-RNP/Sm and anti-Ro/La antibodies (Ab) in lupus nephropathy, we have studied through Contraimmunoelectrophoresis (CIE) and Immunoblotting (IB) the serum of 63 patients diagnosed of systemic lupus erythematosus. Mean age was 36.5 years (15-71) and 90% were females. We...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1992-11-01 00:00:00
abstract：:Two cases of confirmed tuberculous Addison disease, with an increase in size of the adrenal glands are presented. One patient presented also a renal adenocarcinoma; this association is very rare given the small frequency of these diseases. Based on these two cases we emphasize the utility of puncture aspiration with a...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1989-12-01 00:00:00
abstract：:The therapeutic effect of captopril in treating mild to moderate arterial hypertension has been evaluated in 20 patients. During 15 days patients underwent a washout period. Patients then received a single dose of 50 mg of captopril by mouth per day during 4 weeks. Before and after treatment, blood pressure (BP) was c...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1989-03-01 00:00:00
abstract：:A study was conducted to know the rate of non-compliance of antituberculosis therapy among HIV-infected patients, the factors associated with non-compliance and the evolution of these patients. The therapy compliance in 276 tuberculous HIV infected patients diagnosed in two Madrid hospitals was analyzed. Fifty-one pat...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1997-03-01 00:00:00
abstract：:The aim or our study was to evaluate the main clinical and etiological features or primary acute pericarditis with severe pericardial effusion without cardiac tamponade. Our experience included 35 patients with this problem diagnosed in the last 5 years. Patients with a previous potential etiology for acute pericardit...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/s0014-2565(06)72744-8
更新日期：2006-03-01 00:00:00
abstract：:We studied fifty seven episodes of cirrhotic spontaneous bacterial peritonitis in order to know its microbiological, clinical and evolutive characteristics. One third of the patients had presented some previous peritonitis episodes. Ninety three percent of the patients referred some symptoms at time of diagnosis. Asci...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1990-11-01 00:00:00
abstract：:Gestational diabetes is defined as glucose intolerance of variable severity with onset or first recognition during pregnancy. Gestational Diabetes generally disappears as soon as the pregnancy is terminated. The prevalence of gestational diabetes is 2% to 13%, depending on the genetic characteristics and environment o...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：
更新日期：1993-06-01 00:00:00
abstract：:Malign small cell tumors in the thoracopulmonary region is a tumor of neuroectodermic origins with polymorphous and infrequent presentation. It is mostly found among young people, developing an aggressive and severe course. It is a small cell tumor involving small quantities of cytoplasm without glucogen, round or ova...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1994-05-01 00:00:00
abstract：:In order to know the epidemiological, clinical and evolutive characteristics of bacteriemia caused by beta-hemolytic streptococci groups A and B, a retrospective investigation was undertaken of 48 bacteremic episodes observed in adult patients for 10 years (1985-1994). Twenty-two episodes were caused by Group A beta-h...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1995-08-01 00:00:00
abstract：:Three new cases of diffuse pulmonary lymphangioleiomyomatosis are presented. Case number 1 is a female patient who presented repeated pneumotorax and dyspnea without evidence by CT scan and gynecological ultrasound of extrathoracic lesions. This patient did not respond to medroxiprogesterone and died 5 years after the...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：
更新日期：1990-04-01 00:00:00
abstract：:BACKGROUND. In 1997, The Fourth International Workshop-Conference on Gestational Diabetes Mellitus (GDM) recommended the use of Carpenter and Coustan diagnostic criteria instead of those of Sullivan and Mahan used until then. The objective of this work was to study the incidence of GDM in the southeast Madrid area by ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/s0014-2565(02)71008-4
更新日期：2002-03-01 00:00:00
abstract：:We have studied a group of 33 (27 female and 6 male) patients suffering pure essential arterial hypertension, with a mean age of 54.06 years, and who received a daily monodose of chlortalidone. Arterial pressure, blood viscosity at different shearing levels, as well as those parameters capable of modifying this viscos...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1990-09-01 00:00:00
abstract：:The name fetus-in-fetu designates the presence of a tumoral mass containing a homunculus. Fewer than 70 cases have been reported in the literature since its first description about 1800. This entity usually presents in childhood and it is exceptional in adult life. There is an interesting debate regarding its origin a...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：
更新日期：1996-11-01 00:00:00
abstract：BACKGROUND:The immune response to Mycobacterium tuberculosis is primarily mediated by T lymphocytes. In this study an investigation was made of T lymphocytes and their subsets, B lymphocytes and natural cytotoxic cells (Natural Killer, NK) in blood and organic fluids in different tuberculosis conditions. METHODS:Patie...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1996-04-01 00:00:00
abstract：OBJECTIVE:To analyze the different therapeutic attitudes towards patients with arterial hypertension (AH) or white coat hypertension (WCH). DESIGN:Longitudinal, retrospective study after performing a 24 h ambulatory blood pressure monitoring of ABPM. SETTING:Urban health center. PATIENTS:Eighty-six patients aged ove...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：2001-04-01 00:00:00
abstract：:Pancreas transplantation offers the possibility of preventing the development and progression of diabetic lesions by adequate control of hydrocarbon metabolism. Moreover, the diabetic patient is freed from dietary and physical restrictions, as well as from insulin treatment. However, this is achieved at the expense of...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：
更新日期：1989-07-01 00:00:00
abstract：:A case of hemispheric medulloblastoma of cerebellum in a 22 male patient is presented. The patient complained of headache and an intracranial hypertension syndrome progressively appeared. Diagnosis was established by CT scan. Treatment consisted of radical surgery associated to radiotherapy and chemotherapy. Present s...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
