Abstract：
OBJECTIVE:To determine the primary drug resistance (PDR) of Mycobacterium tuberculosis in ten hospitals in the Castile-León Community for a five-year period (1991-1995), in a sanitary area with almost two millions of inhabitants. MATERIAL AND METHODS:The sensitivity of 825 strains of Mycobacterium tuberculosis to antituberculous drugs was studied using the proportion method; 773 strains were from HIV-negative patients and 52 from HIV-positive patients. RESULTS:Thirty-four out of the 824 strains were resistant to one or more drugs: 31 (4%) from HIV-negative patients and 3 (5.7%) from HIV-positive patients. The resistance to the different drugs for strains from HIV-negative patients was: streptomycin, 2.4%; isoniazid, 1.8%; ethambutol, 0.6%, and rifampin, 0.2%. For HIV-positive patients, resistance to streptomycin was 5.7% and to isoniazid 1.9%. Resistance to a single agent was the resistance mode observed most commonly: 23 (2.9%) in HIV-negative patients and 2 (3.3%) in HIV-positive patients. There was not a single strain resistant to isoniazid and rifampin. CONCLUSIONS:The incidence of PR in the surveyed area was low, including isoniazid. The group of HIV-positive patients did not show a significant increase in resistance (p = 0.4; OR, 1.44; 95% CI, 0.43-4.86). Regular surveillance of drug resistance is recommended to adjust therapeutic regimes.
journal_name
Rev Clin Espjournal_title
Revista clinica espanolaauthors
Alberte Castiñeiras A,Pérez Pascual Pkeywords:
subject
Has Abstractpub_date
1999-03-01 00:00:00pages
132-5issue
3eissn
0014-2565issn
1578-1860journal_volume
199pub_type
杂志文章abstract：BACKGROUND:Bartonella henselae infections are closely related to a number of clinical conditions of growing interest in our environment. As cats are the reservoir, and their bites and scratches are the main transmission mechanism, we attempted to study the seroepidemiology of the infection caused by this microorganism ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1998-12-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Since June 2016, there have been outbreaks of hepatitis A in various European countries, mainly affecting men who have sex with men (MSM). The aim of this study was to assess their clinical and epidemiological impact in Cantabria, Spain. MATERIAL AND METHODS:We retrospectively collected all c...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2019.08.005
更新日期：2020-10-01 00:00:00
abstract：:Our objective has been to elaborate an updated Clinical Guide of the Spanish Society of Internal Medicine (SEMI) for the prevention and treatment of glucocorticoids-induced osteoporosis (GIO), identifying and measuring the grade of evidence that supports the given recommendations. For this, we reviewed studies perform...
journal_title：Revista clinica espanola
pub_type： 杂志文章,实务指引
doi：10.1157/13115006
更新日期：2008-01-01 00:00:00
abstract：:Malign small cell tumors in the thoracopulmonary region is a tumor of neuroectodermic origins with polymorphous and infrequent presentation. It is mostly found among young people, developing an aggressive and severe course. It is a small cell tumor involving small quantities of cytoplasm without glucogen, round or ova...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1994-05-01 00:00:00
abstract：:We studied fifty seven episodes of cirrhotic spontaneous bacterial peritonitis in order to know its microbiological, clinical and evolutive characteristics. One third of the patients had presented some previous peritonitis episodes. Ninety three percent of the patients referred some symptoms at time of diagnosis. Asci...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1990-11-01 00:00:00
abstract：:The clinical records of patients attended at emergency hospitals in fifteen hospitals in Madrid, Valencia and Gran Canaria during 1994 were retrospectively analyzed. Seventy-three emergencies related to the consumption of design drugs, hallucinogens or amphetamines (100 times lower than because of opiates or cocaine) ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1997-12-01 00:00:00
abstract：:Sarcoidosis is a disease which presents important clinical differences according to its geographical distribution. Thus, the objective of this study was to evaluate the epidemiologic, clinical, radiologic, and diagnostic characteristics in a series of 30 sarcoidosis patients in the province of Salamanca (representing ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1991-09-01 00:00:00
abstract：OBJECTIVE:To study the prevalence and presentation forms of hereditary hemorrhagic telangiectasia (HHT) among the population in our hospital area. MATERIALS AND METHODS:Descriptive, retrospective study of patients with the diagnosis of HHT from to 1999 at La Fe Hospital, Valencia. Family history, repeated epistaxis, m...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/s0014-2565(01)70935-6
更新日期：2001-11-01 00:00:00
abstract：:A retrospective study is presented of 19 patients who suffered Hypercortisolism who were examined by adrenal gammagraphy, echography, and CT scan in order to evaluate the usefulness of gammagraphy in the diagnostic approximation of this pathology. The gammagraphy findings had an excellent correlation with anatomopatho...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1991-04-01 00:00:00
abstract：:A study was conducted to know the rate of non-compliance of antituberculosis therapy among HIV-infected patients, the factors associated with non-compliance and the evolution of these patients. The therapy compliance in 276 tuberculous HIV infected patients diagnosed in two Madrid hospitals was analyzed. Fifty-one pat...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1997-03-01 00:00:00
abstract：:Although the number of elderly needing health care is increasing in Spain, geriatric patients do not receive enough attention or support when compared to that given in other countries. When the elderly get sick they present peculiar and special problems which should be attended following their needs. Because in hospit...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1989-03-01 00:00:00
abstract：:In order to assess the bacteriology of bronchial secretion samples, 40 patients in the intensive care unit who had developed fever and pulmonary infiltrates during mechanical ventilation have been studied. In each patient bronchial secretion samples were obtained by a double lumen distally-plugged telescopic catheter ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1989-02-01 00:00:00
abstract：:Without a doubt blood pressure autoevaluation facilitates hypertension diagnosis, control and treatment. This also helps research, makes possible costs reduction and is an easy, safe, and useful method. Its use should be favored in the new model of patient-based clinical practice. ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13072969
更新日期：2005-03-01 00:00:00
abstract：BACKGROUND:Nosocomial infection (NI) is associated with an increase in resource consumption. The estimation of extra costs attributable to NI in a group of patients with catheter-related bacteremia (CRB) was the objective of the present study. METHODS:A matched case-control, study was conducted in a cohort population....
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1998-10-01 00:00:00
abstract：OBJECTIVE:Several studies have reported that a higher degree of hemoconcentration in patients admitted for the treatment of acute heart failure (HF) constitutes a favorable prognostic factor in the year following the index episode. The objective of this study was to evaluate whether the highest degree of hemoconcentrat...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2018.07.003
更新日期：2019-01-01 00:00:00
abstract：:Ogilvie's syndrome (OS) is a clinical condiction with the symptoms, signs and radiological appearances of acute bowell obstruction but without any apparent mechanical cause. Diagnosis and treatment are often delayed and many patients are still inappropriately managed which in turn results in an increase in morbidity a...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1995-11-01 00:00:00
abstract：BACKGROUND:The increase in intraabdominal pressure (IAP) has been correlated with increased creatinine levels in patients with heart failure with severely reduced left ventricular ejection fraction (HFrEF). However, IAP has not been examined in more stable patients or those with heart failure with preserved ejection fr...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2020.01.011
更新日期：2020-07-09 00:00:00
abstract：:Antibodies (type IgG) against the A 60 antigen (Mycobacterium bovis, BCG) and an antigen of Mycobacterium tuberculosis were studied by ELISA in 79 patients with not tuberculous disease: 16 lung carcinoma, 16 hepatic cirrhosis and 47 patients with pulmonary disease. 59.5% and 50.6% of the patients showed antibodies aga...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1992-04-01 00:00:00
abstract：:The clinical histories of all the patients with hemoptysis who underwent bronchofibroscopy (FB) during a period of 5 years (1981-1986) are revised. 25.6% (108 out of 702) of the endoscopic explorations were performed in patients without radiographic pleuropulmonary abnormalities with a definite pathology. In these pat...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1990-04-01 00:00:00
abstract：:This review proposes a more optimistic view of Alzheimer's disease (AD), in contrast to that contributed by the ageing of the population and the failure of potentially curative therapies (vaccines and others). Treatment failure is likely due to the fact that AD gestates in the brain for decades but manifests in old ag...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2016.05.010
更新日期：2016-12-01 00:00:00
abstract：:The purpose of this study was to review the epidemiological aspects and the characteristics of the thyroid disfunction produced by amiodarone in Catalonia, an area with type I endemic goiter. For this purpose, three groups of patients have been studied: 1) 102 patients with prolonged amiodarone treatment, out of whom ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1991-02-01 00:00:00
abstract：:The appearance of diabetic nephropathy and its progression towards renal failure can be prevented if an early treatment is instituted. However, diabetes is currently one of the main causes of entry into a dialysis program. Therefore, the diagnostic characteristics of renal disease in 105 patients who started dialysis ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1999-01-01 00:00:00
abstract：:The antibiotherapy resistance evolution and the appearance of new enterobacter in our ICU's flora have been studied. A total of 638 bacterial samples were studied. The most frequent isolated pathogens were: Pseudomonas aeruginosa (182 strands), Escherichia coli (108 strands), Staphylococcus epidermidis (99 strands) an...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1990-04-01 00:00:00
abstract：:We report the clinical, radiological and microbiological features of ten patients diagnosed of pyogenic sacroiliitis in an Internal Medicine Department during a 13 years period. Clinical signs and radiological or scintigraphical findings were present in every case. Staphylococcus aureus was isolated in blood cultures ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1993-10-01 00:00:00
abstract：:The contributions of Santiago Ramon y Cajal to Modern medicine are innumerable. This large scientist and humanist, a man ahead of his time, spoke for the first time such concepts as angiogenesis, which represents one of the most innovative fields for oncology today, in addition to conducting experimental research on t...
journal_title：Revista clinica espanola
pub_type： 传,历史文章,杂志文章
doi：10.1016/s0014-2565(08)76037-5
更新日期：2008-12-01 00:00:00
abstract：OBJECTIVES:We evaluated the effect of an intervention on certain quality indicators employed for improving the treatment of hospital hyperglycemia. MATERIAL AND METHODS:A multicenter cross-sectional study was conducted on patients with hyperglycemia hospitalized in the internal medicine departments of 44 hospitals eva...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2016.05.006
更新日期：2016-10-01 00:00:00
abstract：:Type 2 diabetes mellitus is a major health problem with high prevalence, morbidity and mortality, and its medical treatment is growing in complexity due to patients' diverse clinical conditions. This article presents a consensus document by the Diabetes, Obesity and Nutrition Group of the Spanish Society of Internal M...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2020.06.005
更新日期：2020-07-13 00:00:00
abstract：:The presence of anti-HIV (human immunodeficiency virus) antibodies was determined in 325 subjects. The samples were taken from 138 convicts from Carabanchel and Ocaña I jail, 162 parenteral drug addicts (PDA) from a center for rehabilitation of drug addicts (CR), and from 14 family members and 11 stable couples of the...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1989-04-01 00:00:00
abstract：BACKGROUND:Despite a steady decrease in its incidence, pneumonia caused by Pneumocystis carinii (PCP) are still diagnosed, and they occur frequently in patients unaware of being infected with the human immunodeficiency virus (HIV). Since it is a disease with a high mortality risk, its early diagnosis and therapy would ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/s0014-2565(02)71100-4
更新日期：2002-08-01 00:00:00
abstract：:Toxic shock syndrome (TSS) is a potentially fatal acute disease preferentially affecting menstruating women and is related to the use of vaginal tampons seems to be due to an specific exotoxin produced by some Staphylococcus aureus strains. We present here the case of a male patients suffering cavitated pneumonia who ...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：
更新日期：1990-05-01 00:00:00
