Abstract：
OBJECTIVE:To describe the incidence and characteristics of the infection caused by Mycobacterium tuberculosis in patients with autoimmune diseases. PATIENTS AND METHODS:Searching in the database of the department at our institution, all new cases of tuberculosis from 1991 to 2000 were identified in patients with autoimmune diseases; the total follow-up time was calculated as the difference between first and last visits. Time with immunosuppressive drug therapy was obtained for patients with rheumatoid arthritis from a database oriented to the longitudinal follow-up of these patients. The incidence density was calculated as the quotient between the absolute frequency of cases and the sum of individual periods at risk for each subgroup. RESULTS:Fifteen cases of tuberculosis were identified from 3,634 risk patients followed for an accumulated period of 9,795 years (overall incidence 153 per 100,000 patients-year). Fourteen patients were receiving disease-modifying drugs and eleven were receiving corticosteroids at diagnosis. The location of tuberculosis infection was the lung for 33.3% of cases. The incidence by drugs in patients with rheumatoid arthritis was 143 per 100,000 patients-year with methotrexate, 2,703 per 100,000 patients-year with azathioprin, 7,692 per 1,000 patients-year with cyclophosphamide, and 4,878 per 100,000 patients-year for anti-TNFalpha. CONCLUSIONS:Compared with the general population, the incidence density of tuberculosis is increasing in our population, with a higher frequency of extrapulmonary involvement. The incidence density is variable among patients with rheumatoid arthritis depending upon the used drugs.
journal_name
Rev Clin Espjournal_title
Revista clinica espanolaauthors
Vadillo Font C,Hernández-García C,Pato E,Morado IC,Salido M,Júdez E,Macarrón P,Fernández-Gutiérrez B,Abásolo L,Jover JAdoi
10.1157/13045537keywords:
subject
Has Abstractpub_date
2003-04-01 00:00:00pages
178-82issue
4eissn
0014-2565issn
1578-1860pii
13045537journal_volume
203pub_type
杂志文章abstract：:The therapeutic effect of captopril in treating mild to moderate arterial hypertension has been evaluated in 20 patients. During 15 days patients underwent a washout period. Patients then received a single dose of 50 mg of captopril by mouth per day during 4 weeks. Before and after treatment, blood pressure (BP) was c...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1989-03-01 00:00:00
abstract：:The clinical characteristics of systolic and diastolic hypertension in 75 and of systolic hypertension in 50 elderly patients have been studied and the results have been compared to those obtained in 23 normotense elderly controls and 500 young patients with essential hypertension. A greater incidence in cardiovascula...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1989-06-01 00:00:00
abstract：:Two patients with advanced atherosclerotic vascular disease developed multiple cholesterol emboli. In both patients the clinical presentation included livedo reticularis of the lower part of the body and purple toes with small areas of distal necrosis and ulceration. The predisposing factors are operative vascular pro...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：:Comparative performance of four methods (IFI, IgM anti-VCA, Organon Teknika; ELISA, IgM anti VCA, Incstar Corp and Pharmacia Diagnostic Inc; ELISA IgM against a group of several antigens which principal component is EBNA, Behring Institute) to detect antibodies (Abs) against Epstein-Barr virus in 180 patients (group 1...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1992-10-01 00:00:00
abstract：INTRODUCTION:The use of bone marrow transplantation (BMT) in leukemia treatment is associated with high early morbid-mortality rates. Therefore, to identify morbid-mortality risk factors in this setting can be useful to improve therapeutic ratio. METHODS:We studied 15 variables in 46 patients with chronic myeloid leuk...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1994-08-01 00:00:00
abstract：:A case of hemispheric medulloblastoma of cerebellum in a 22 male patient is presented. The patient complained of headache and an intracranial hypertension syndrome progressively appeared. Diagnosis was established by CT scan. Treatment consisted of radical surgery associated to radiotherapy and chemotherapy. Present s...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:One hundred and thirty six patients presenting pleural effusion and whose diagnosis was obtained by clinical, biochemical, bacteriological, cytological and histological methods have been studied and classified into seven groups: 20 transudates, 29 inflammatory, 25 tuberculosis, 25 non adenocarcinoid neoplasias, 24 ade...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1992-02-01 00:00:00
abstract：BACKGROUND:Nosocomial infection (NI) is associated with an increase in resource consumption. The estimation of extra costs attributable to NI in a group of patients with catheter-related bacteremia (CRB) was the objective of the present study. METHODS:A matched case-control, study was conducted in a cohort population....
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1998-10-01 00:00:00
abstract：:Given the increasing interest in Lyme borreliosis in our community, and the lack of epidemiological studies in our country, we have considered convenient to analyze the presence of anti-Borrelia burgdorferi antibodies in a group of workmen who we have considered at high risk since they carry out their everyday work in...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1990-10-01 00:00:00
abstract：UNLABELLED:Cystatin C (CysC) is a protease encoded by housekeeping genes. Although its prognostic value in heart failure (HF) is well known, it is debatable whether this value is due to the greater accuracy of CysC in calculating the glomerular filtration rate or to its involvement in pathological ventricular remodelli...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2015.11.003
更新日期：2016-03-01 00:00:00
abstract：OBJECTIVE:To study the evolution of antithrombin (AT) and plasma fibrinogen levels and of hematologic values among women in child-bearing age on treatment with the new hormonal oral contraceptives (HOC): in microdose, ultramicrodose and Diane-35. METHOD:Retrospective review of 100 randomized cases out of a total regis...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/s0014-2565(01)70954-x
更新日期：2001-12-01 00:00:00
abstract：:The presence of anti-HIV (human immunodeficiency virus) antibodies was determined in 325 subjects. The samples were taken from 138 convicts from Carabanchel and Ocaña I jail, 162 parenteral drug addicts (PDA) from a center for rehabilitation of drug addicts (CR), and from 14 family members and 11 stable couples of the...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1989-04-01 00:00:00
abstract：BACKGROUND:The RS3PE syndrome is a recently described uncommon disorder in the elderly patient; in the initial reports, it was characterized by an excellent prognosis with total remission. In contrast with rheumatoid arthritis and polymyalgia rheumatic, it has been related to HLA B7. Further works have questioned its b...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1999-12-01 00:00:00
abstract：:Patobiographic data of four brilliant painters who lived in three different centuries (Goya [XVIII], Fortuny and Van Gogh [XIX] and Portinari [XX]), were examined in search for a suspected lead poisoning. It is concluded that Goya's disease and deafness was probably caused by lead poisoning. Fortuny's death was probab...
journal_title：Revista clinica espanola
pub_type： 传,历史文章,杂志文章
doi：10.1016/s0014-2565(06)72707-2
更新日期：2006-01-01 00:00:00
abstract：:Central venous catheters are essential in modern-day medical practice, particularly in intensive care units. Although such catheters provide necessary vascular access, their use puts patients at risk of mechanical and infectious complications. Unfortunately, these complications are associated with an increase of the m...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：10.1157/13084771
更新日期：2006-01-01 00:00:00
abstract：BACKGROUND:Description of the patients admitted in the general Internal Medicine (IM) departments of the Public Health System in Andalusia (Spain) (PHSA) during 2002. PATIENTS AND METHODS:It is an analysis of the Minimum Basic Set of Data (MBSD) and its management by the Diagnostic Related Groups (DRG) of admission ep...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13084760
更新日期：2006-01-01 00:00:00
abstract：OBJECTIVE:To know the characteristics of nocardiosis in HIV infected patients. PATIENTS AND METHODS:Retrospective analysis of HIV infected patients with a concomitant Nocardia spp. infection in nine Andalusian hospitals. RESULTS:Eighteen cases of nocardiosis were studied. Seventeen patients were males and the mean ag...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/s0014-2565(02)71084-9
更新日期：2002-07-01 00:00:00
abstract：UNLABELLED:The increase in the mean populational age has increased the number of elderly people eligible for cardiac surgery. The aortic pathology represents the most common valvular pathology, mainly of degenerative etiology. The efficiency of the aortic valve replacement in people aged over 75 years was studied, with...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1998-05-01 00:00:00
abstract：:The clinical features of seven patients with persistent hiccup are reported. Hiccup did not respond to the usual therapies and resolved with baclofen. The administration guidelines and secondary effects are discussed. The authors suggest baclofen should be considered the drug of choice for treating persistent hiccup. ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1996-12-01 00:00:00
abstract：:For patients to be able to make decisions autonomously (and to grant informed consent), they must have information, understanding, freedom and willingness, with competence a prerequisite for autonomy. Clinicians are often faced with patients lacking competence to make decisions but detect less than half of such cases ...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：10.1016/j.rce.2019.04.009
更新日期：2020-05-01 00:00:00
abstract：:Sarcoidosis is a disease which presents important clinical differences according to its geographical distribution. Thus, the objective of this study was to evaluate the epidemiologic, clinical, radiologic, and diagnostic characteristics in a series of 30 sarcoidosis patients in the province of Salamanca (representing ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1991-09-01 00:00:00
abstract：:Pancreas transplantation offers the possibility of preventing the development and progression of diabetic lesions by adequate control of hydrocarbon metabolism. Moreover, the diabetic patient is freed from dietary and physical restrictions, as well as from insulin treatment. However, this is achieved at the expense of...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：
更新日期：1989-07-01 00:00:00
abstract：:Our objective has been to elaborate an updated Clinical Guide of the Spanish Society of Internal Medicine (SEMI) for the prevention and treatment of glucocorticoids-induced osteoporosis (GIO), identifying and measuring the grade of evidence that supports the given recommendations. For this, we reviewed studies perform...
journal_title：Revista clinica espanola
pub_type： 杂志文章,实务指引
doi：10.1157/13115006
更新日期：2008-01-01 00:00:00
abstract：:This review proposes a more optimistic view of Alzheimer's disease (AD), in contrast to that contributed by the ageing of the population and the failure of potentially curative therapies (vaccines and others). Treatment failure is likely due to the fact that AD gestates in the brain for decades but manifests in old ag...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2016.05.010
更新日期：2016-12-01 00:00:00
abstract：:We discuss the case of a 22-year-old female, carrying of antibodies to against human immunodeficiency virus (HIV), who developed several tumors on different bone localizations, which corresponded to plurifocal bone tuberculosis. We reviewed multifocal bone tuberculosis reports in the literature. The exceptionally of t...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：
更新日期：1992-06-01 00:00:00
abstract：:Cutaneous larva migrans (CLM) is a frequent dermal disease in travelers, caused by larvae of nonhuman ancylostoma. We describe 34 outside cases of CLM diagnosed since January 1991 to June 2002. Nineteen male and female. Age: 35.7 years (20-60). The total number of CLM infestations was 73, 83.5% in feet. In five cases ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/s0014-2565(04)71567-2
更新日期：2004-12-01 00:00:00
abstract：:The watermelon stomach is a vascular malformation at the gastric antrum which is responsible for chronic bleeding. We report here nine patients (5 females and 4 males) referred to our Department from December 1990 to May 1995 with ferropenic anemia resulting from chronic gastrointestinal bleeding and with the diagnosi...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1996-05-01 00:00:00
abstract：OBJECTIVE:To evaluate whether fast track of patients with myocardial infarction, from the emergency department to the intensive care unit, significantly decreased the intrahospital delay in the administration of anti-thrombolytic agents. PATIENTS AND METHODS:Descriptive study performed in two phases (12 and 15 months,...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1999-09-01 00:00:00
abstract：:Type 2 diabetes mellitus is a major health problem with high prevalence, morbidity and mortality, and its medical treatment is growing in complexity due to patients' diverse clinical conditions. This article presents a consensus document by the Diabetes, Obesity and Nutrition Group of the Spanish Society of Internal M...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2020.06.005
更新日期：2020-07-13 00:00:00
abstract：UNLABELLED:An inappropriate hospital use, defined as hospital utilization that could have been occurred at a lower attending level or in less time, increases costs, creates inefficient management and influences on attending quality. The objective of this work was to evaluate the appropriateness and inappropriateness of...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：2000-12-01 00:00:00
