Abstract：
INTRODUCTION:The use of bone marrow transplantation (BMT) in leukemia treatment is associated with high early morbid-mortality rates. Therefore, to identify morbid-mortality risk factors in this setting can be useful to improve therapeutic ratio. METHODS:We studied 15 variables in 46 patients with chronic myeloid leukemia (CML) treated with cyclophosphamide, total body irradiation (TBI) and allogeneic BMT. A multivariant analysis with an unconditional logistic regression model was used. RESULTS:Variables found to be related with early mortality included general state of health and acute graft versus host disease. Patients with a Karnofsky index (KI) between 60% and 80% had a higher risk of early death than those with a KI between 90 and 100%. Patients who developed severe (grade II-IV) acute graft versus host disease (AGVHD), had a relative risk of 15.62 (IC 95%: 3.16-77.34) compared with those who do not. Time between diagnosis and BMT contributed to the creation of the mathematical model without reaching statistical significance. CONCLUSIONS:In this series and in the range of the parameters analysed, general state of health according to KI, and the appearance of severe AGVHD are the variables related with a higher risk of early mortality.
journal_name
Rev Clin Espjournal_title
Revista clinica espanolaauthors
Algara M,Valls A,Ruiz V,Carreras E,Sierra J,Grañena Asubject
Has Abstractpub_date
1994-08-01 00:00:00pages
607-12issue
8eissn
0014-2565issn
1578-1860journal_volume
194pub_type
杂志文章abstract：BACKGROUND:Nosocomial infection (NI) is associated with an increase in resource consumption. The estimation of extra costs attributable to NI in a group of patients with catheter-related bacteremia (CRB) was the objective of the present study. METHODS:A matched case-control, study was conducted in a cohort population....
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1998-10-01 00:00:00
abstract：:Chronic obstructive pulmonary disease (COPD) encompasses a group of diseases characterized by chronic airway obstruction. This broad diagnostic umbrella includes several clinical phenotypes that overlap and respond differently to each type of therapeutic intervention. Roflumilast is a drug belonging to the new therape...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：10.1016/S0014-2565(11)70008-X
更新日期：2011-03-01 00:00:00
abstract：:Type 2 diabetes mellitus is a major health problem with high prevalence, morbidity and mortality, and its medical treatment is growing in complexity due to patients' diverse clinical conditions. This article presents a consensus document by the Diabetes, Obesity and Nutrition Group of the Spanish Society of Internal M...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2020.06.005
更新日期：2020-07-13 00:00:00
abstract：:Cancer of unknown primary site (CUPS) is a heterogeneous entity defined by the presence of a histologically-proven metastatic neoplasm, in which the original tumor cannot be identified after a targeted study. The current guidelines for CUPS focus is not based on the search for the primary neoplasm but rather on the id...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/s0014-2565(09)71820-x
更新日期：2009-07-01 00:00:00
abstract：OBJECTIVE:To know the characteristics of nocardiosis in HIV infected patients. PATIENTS AND METHODS:Retrospective analysis of HIV infected patients with a concomitant Nocardia spp. infection in nine Andalusian hospitals. RESULTS:Eighteen cases of nocardiosis were studied. Seventeen patients were males and the mean ag...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/s0014-2565(02)71084-9
更新日期：2002-07-01 00:00:00
abstract：:Anisakis simplex is a nematode which parasitizes mainly fish and cephalopods and accidentally human beings after ingestion. Apart from the different digestive syndromes, this organism has recently been involved as cause of IgE-mediated allergic reactions of variable degree (urticaria to severe angioedema). In this rep...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1998-09-01 00:00:00
abstract：:The watermelon stomach is a vascular malformation at the gastric antrum which is responsible for chronic bleeding. We report here nine patients (5 females and 4 males) referred to our Department from December 1990 to May 1995 with ferropenic anemia resulting from chronic gastrointestinal bleeding and with the diagnosi...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1996-05-01 00:00:00
abstract：:Six patients with severe and complicated falciparum malaria (6.7 +/- 2.7 WHO criteria) were admitted to our Intensive Care Unit. All patients acquired the disease while travelling in tropical Africa without appropriate chemoprophylaxis. The clinical manifestations included hyperpyrexia (all patients), chills (4), swea...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1998-08-01 00:00:00
abstract：:A case of diffuse mediastinal lipomatosis (ML) is described, associated to exogenous obesity, infrequent entity, which is comprehended within the causes which can cause mediastinal broadening. The clinical characteristics of our observation and the general aspects of interest are reviewed for this type of mediastinal ...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：
更新日期：1993-04-01 00:00:00
abstract：INTRODUCTION AND OBJECTIVES:There is a great variability in the prevalence of anemia in heart failure (HF) according to cohort based studies where the majority of patients have depressed left ventricular ejection fraction (LVEF). Our study has aimed to evaluate the prevalence of anemia in HF within the usual hospital c...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13119912
更新日期：2008-05-01 00:00:00
abstract：:The appearance of diabetic nephropathy and its progression towards renal failure can be prevented if an early treatment is instituted. However, diabetes is currently one of the main causes of entry into a dialysis program. Therefore, the diagnostic characteristics of renal disease in 105 patients who started dialysis ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1999-01-01 00:00:00
abstract：:Inflammatory pseudotumor (IP) is a rare pathological entity. Although, the pulmonary affection is the most frequent, any other organ can be involved. Its etiopathology is unknown. The disease is considered as a reactive process constituted by chronic inflammatory elements and a benign behavior. The lack of a specific ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1991-12-01 00:00:00
abstract：OBJECTIVE:To know the rate of occurrence of monoclonal bands in a clinical laboratory as an estimate of monoclonal gammopathy incidence, and to detect the proportion of these bands in which an explicit clinical diagnosis or follow-up request is not established. Other objectives are to describe its distribution and the ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13075569
更新日期：2005-05-01 00:00:00
abstract：UNLABELLED:The increase in the mean populational age has increased the number of elderly people eligible for cardiac surgery. The aortic pathology represents the most common valvular pathology, mainly of degenerative etiology. The efficiency of the aortic valve replacement in people aged over 75 years was studied, with...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1998-05-01 00:00:00
abstract：INTRODUCTION:The role of glucose elevation above levels considered normal in non- diabetic patients with acute coronary syndromes (ACS) is not adequately defined. The aim of this study was to determine the association between serum glucose at admission and 1-year mortality in this type of patients. METHODS:We studied ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13088586
更新日期：2006-06-01 00:00:00
abstract：:A case is presented of Cushing's syndrome due to macronodular bilateral adrenal hyperplasia which is ACTH-independent as was demonstrated by the undetectable basal and after stimulation with metoprolol ACTH plasma levels. High cortisol levels is associated in this patient with empty sella turcica and anterior panhypop...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1992-03-01 00:00:00
abstract：:We have reviewed the clinical histories of 1,815 immunocompromised patients seen in "La Paz Hospital" over a period of 6 years, in order to study the incidence and clinical forms of tuberculosis (TB) in this group of patients. We have distributed the patients into three groups: Group A: 1,372 patients with neoplasia, ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1989-04-01 00:00:00
abstract：BACKGROUND:Despite a steady decrease in its incidence, pneumonia caused by Pneumocystis carinii (PCP) are still diagnosed, and they occur frequently in patients unaware of being infected with the human immunodeficiency virus (HIV). Since it is a disease with a high mortality risk, its early diagnosis and therapy would ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/s0014-2565(02)71100-4
更新日期：2002-08-01 00:00:00
abstract：:The cerebral trunk infection by Listeria monocytogenes is a very rare process, with only 24 described cases and only 2 in immunodepressed patients. We present a new case of cerebral trunk encephalitis caused by Listeria in a patient diagnosed of Polyarteritis nodosa on steroids and cyclophosamide treatment and fatal e...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1990-11-01 00:00:00
abstract：:Correct functioning of the Ethics Committee (EC) guarantees respect to the rights of the subjects participating in clinical research. The European transposition of the clinical trial guidelines by the Royal Decree (RD) 223/2004 February 6 speeds up and simplifies the administrative procedures for the authorization of ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13079764
更新日期：2005-10-01 00:00:00
abstract：INTRODUCTION:The day hospital is an alternative to hospitalization. This alternative improves accessibility and comfort of the patients, and avoids hospitalizations. Nevertheless, the efficacy of the polyvalent medical day hospital in avoiding hospitalizations has not been evaluated. OBJECTIVE:To analyze hospital stay...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2011.08.003
更新日期：2012-02-01 00:00:00
abstract：BACKGROUND:In the last few years, Strongyloides stercoralis has been repeatedly recovered from indigenous farmers in the Safor area (Valencia Community). The relationship between the different occupational activities, mainly farming, and the presence of strongyloidiasis was investigated. PATIENTS AND METHODS:A paired ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/s0014-2565(01)70755-2
更新日期：2001-02-01 00:00:00
abstract：OBJECTIVE:To determine the appearance of type 2 diabetes mellitus (DM2) and impaired fasting glucose (IFG) at five years of follow-up in a known non-diabetic population. PATIENTS AND METHODS: DESIGN:nested case control studies (case s-control into a cohort) developed in two stages: 1) identification and characterizat...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/s0014-2565(09)70351-0
更新日期：2009-01-01 00:00:00
abstract：UNLABELLED:Cystatin C (CysC) is a protease encoded by housekeeping genes. Although its prognostic value in heart failure (HF) is well known, it is debatable whether this value is due to the greater accuracy of CysC in calculating the glomerular filtration rate or to its involvement in pathological ventricular remodelli...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2015.11.003
更新日期：2016-03-01 00:00:00
abstract：:The purpose of this study is to determine the characteristics of spirometric performance in a group of smokers and to carry out a prospective study of the changes in ventilatory lung function after smoking withdrawal. The ventilatory lung function was studied in 90 smokers and 30 non-smokers. Afterwards the smokers we...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1993-03-01 00:00:00
abstract：:We have studied a group of 33 (27 female and 6 male) patients suffering pure essential arterial hypertension, with a mean age of 54.06 years, and who received a daily monodose of chlortalidone. Arterial pressure, blood viscosity at different shearing levels, as well as those parameters capable of modifying this viscos...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1990-09-01 00:00:00
abstract：OBJECTIVES:To evaluate the scientific output in Biomedicine and Health Sciences in Andalusia in the context of the published works on the national scientific output in the last few years. MATERIAL:Descriptive study with seven different information sources: a) final Report of the Experts Committee on Documentation from...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1996-09-01 00:00:00
abstract：:We here present the case of a patient who starts with a progressive vision loss, observing in the radiologic exam herniation of optic chiasma in a primary empty sella turcica. Based on this case, we have performed a review of this clinical picture and point out the most important aspects in the literature. ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1991-04-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Atrial fibrillation (AF) is the most common type of arrhythmia. The purpose of this study was to determine the prevalence of atrial fibrillation and its relationship with cardiovascular risk factors in Spain. METHODOLOGY:Cross-sectional study based on a grouped analysis of 17,291 randomized i...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2014.06.006
更新日期：2014-12-01 00:00:00
abstract：:The increase in the incidence of tuberculosis infection in the last few years has caused a recurrence of atypical clinical forms, as well as the development of associations and uncommon complications during the clinical course, which include the adult respiratory distress syndrome (ARDS) and septic shock. Three patien...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1995-03-01 00:00:00
