Abstract:
:Correct functioning of the Ethics Committee (EC) guarantees respect to the rights of the subjects participating in clinical research. The European transposition of the clinical trial guidelines by the Royal Decree (RD) 223/2004 February 6 speeds up and simplifies the administrative procedures for the authorization of clinical trials. However, it is clear that it has meant a considerable effort on the work and administrative load of the ECs. An account is made on the adaptation procedures of the EC of the Hospital La Paz to apply the new Royal Decree and a short reflection is made on the most immediate consequences and repercussions in the EC activity.
journal_name
Rev Clin Espjournal_title
Revista clinica espanolaauthors
Fernández de Uzquiano E,Lavilla Uriol P,Alvarez-Sala Walther Rdoi
10.1157/13079764keywords:
subject
Has Abstractpub_date
2005-10-01 00:00:00pages
493-5issue
10eissn
0014-2565issn
1578-1860pii
13079764journal_volume
205pub_type
杂志文章abstract::The editors of Revista Clínica Española (Rev Clin Esp) inform on their editorial activity during the last 12 months (November 2010 to October 2011): (a) Objectives and attainments during 2011, (b) editorial activity, and (c) objectives for 2012. In 2011 we have updated the editorial algorithm (revision by the responsi...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:10.1016/j.rce.2011.11.004
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:In recent years, there has been an increase of drugs poisoning cases seen in the Emergency Department. This study has aimed to evaluate the characteristics of these cases in the Ramón and Cajal Hospital in Madrid. MATERIALS AND METHODS:A descriptive analysis about the drug poisonings diagnosed in 2004 was p...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:10.1157/13127603
更新日期:2008-10-01 00:00:00
abstract::One hundred and thirty six patients presenting pleural effusion and whose diagnosis was obtained by clinical, biochemical, bacteriological, cytological and histological methods have been studied and classified into seven groups: 20 transudates, 29 inflammatory, 25 tuberculosis, 25 non adenocarcinoid neoplasias, 24 ade...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:
更新日期:1992-02-01 00:00:00
abstract::A case is presented of Cushing's syndrome due to macronodular bilateral adrenal hyperplasia which is ACTH-independent as was demonstrated by the undetectable basal and after stimulation with metoprolol ACTH plasma levels. High cortisol levels is associated in this patient with empty sella turcica and anterior panhypop...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:
更新日期:1992-03-01 00:00:00
abstract:OBJECTIVE:Analyze the effect of AM3, an oral immunomodulator, on the exacerbations and on the use of antibiotics in patients with chronic obstructive pulmonary disease (COPD). DESIGN:Systematic search of controlled clinical trials that used AM3 in some treatment group and that included data on the clinical effects of ...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:10.1157/13065976
更新日期:2004-09-01 00:00:00
abstract::Gestational diabetes is defined as glucose intolerance of variable severity with onset or first recognition during pregnancy. Gestational Diabetes generally disappears as soon as the pregnancy is terminated. The prevalence of gestational diabetes is 2% to 13%, depending on the genetic characteristics and environment o...
journal_title:Revista clinica espanola
pub_type: 杂志文章,评审
doi:
更新日期:1993-06-01 00:00:00
abstract::Painful legs and moving toes syndrome is a rare medical picture characterized by involuntary movements of the toes or the whole foot and pain in lower limbs. However, this must be kept in mind due to its association with other diseases and its possibility of being the first symptom. Spinal cord and cauda equina diseas...
journal_title:Revista clinica espanola
pub_type: 杂志文章,评审
doi:10.1157/13102318
更新日期:2007-05-01 00:00:00
abstract::The proportion of diabetic patients who are hospitalised for stroke has been increasing in recent years, currently reaching almost a third of all cases of stroke. In addition, about half of patients with acute stroke present hyperglycaemia in the first hours of the stroke. Although hyperglycaemia in the acute phase of...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:10.1016/j.rce.2015.06.005
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVE:To determine the appearance of type 2 diabetes mellitus (DM2) and impaired fasting glucose (IFG) at five years of follow-up in a known non-diabetic population. PATIENTS AND METHODS: DESIGN:nested case control studies (case s-control into a cohort) developed in two stages: 1) identification and characterizat...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:10.1016/s0014-2565(09)70351-0
更新日期:2009-01-01 00:00:00
abstract:INTRODUCTION:This study has aimed to describe cardiovascular risk factors (CVRF) associated to stroke and their detection and monitoring during the acute episode and the recommendations on hospital discharge. The hypothesis was to check if the integral care of the internist improved the care to these patients. MATERIA...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:10.1157/13124313
更新日期:2008-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The Computerized Registry of Patients with Venous Thromboembolism (RIETE) is a prospective registry that consecutively includes patients diagnosed with venous thromboembolism. We compared the clinical presentation and response to anticoagulant treatment in patients with idiopathic venous throm...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:10.1016/j.rce.2014.05.017
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVES:We evaluated the effect of an intervention on certain quality indicators employed for improving the treatment of hospital hyperglycemia. MATERIAL AND METHODS:A multicenter cross-sectional study was conducted on patients with hyperglycemia hospitalized in the internal medicine departments of 44 hospitals eva...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:10.1016/j.rce.2016.05.006
更新日期:2016-10-01 00:00:00
abstract::A retrospective study is discussed, in which the disorder of pancreatic enzymes in hospitalized patients because of an acute infectious gastroenteritis is analyzed. Of 30 cases, 15 showed a raise in lipase levels, being over 1,000 IU in five of them. There was no associated raise in amylase levels. Patients with high ...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:
更新日期:1992-10-01 00:00:00
abstract:BACKGROUND:Description of the patients admitted in the general Internal Medicine (IM) departments of the Public Health System in Andalusia (Spain) (PHSA) during 2002. PATIENTS AND METHODS:It is an analysis of the Minimum Basic Set of Data (MBSD) and its management by the Diagnostic Related Groups (DRG) of admission ep...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:10.1157/13084760
更新日期:2006-01-01 00:00:00
abstract::Coeliac disease is the most frequent malabsortive syndrome in daily practice. However, its true prevalence is not exactly known. The symptoms vary from patient to patient, ranging from the classic presentation with diarrhea, weight loss and fatigue to oligosymptomatic forms, being the latter more common in adults. We ...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract:OBJECTIVES:To describe the evolution of smoking habits in the general population of Barcelona from 1983 to 1992 and motivation of smokers and the perceived social pressure to leave smoking in 1992. DESIGN:Cross-sectional descriptive study of trends. PLACE AND PARTICIPANTS: From 1983 to 1992 two health surveys were con...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:
更新日期:1996-06-01 00:00:00
abstract::Two cases are reported of women aged 18 and 36 years respectively who developed a typical picture of hyperthyroidism by Graves Basedow disease (primary hyperthyroidism, diffuse goiter with increased uptake, positive stimulating thyroid antibodies, exophthalmos). These women had taken drugs for obesity which were prepa...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:
更新日期:1996-08-01 00:00:00
abstract::The polyacrylamide gel electrophoresis of spinal fluid from 488 patients suffering neurological diseases and from a control group are reviewed. One hundred and eleven cases (22.7%) showed oligoclonal bands (OB). The highest percentage of OB appeared in the group of patients with definite multiple sclerosis (84%), foll...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:
更新日期:1989-10-01 00:00:00
abstract::HepatitisC virus infection is a significant public health problem. The introduction of direct-acting antiviral agents, whose efficacy is greater than 90% in all patient groups (including those with cirrhosis), has represented a highly relevant change compared with classical interferon-based therapies. Tolerance for th...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:10.1016/j.rce.2017.07.006
更新日期:2018-01-01 00:00:00
abstract::More than 100 million people ascend to high mountainous areas worldwide every year. At nonextreme altitudes (<5500 m), 10-85% of these individuals are affected by acute mountain sickness, the most common disease induced by mild-moderate hypobaric hypoxia. Approximately 140 million individuals live permanently at heigh...
journal_title:Revista clinica espanola
pub_type: 杂志文章,评审
doi:10.1016/j.rce.2019.12.013
更新日期:2020-03-17 00:00:00
abstract::The clinical features of seven patients with persistent hiccup are reported. Hiccup did not respond to the usual therapies and resolved with baclofen. The administration guidelines and secondary effects are discussed. The authors suggest baclofen should be considered the drug of choice for treating persistent hiccup. ...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:
更新日期:1996-12-01 00:00:00
abstract:OBJECTIVES:Celiac disease is a chronic immune-mediated disease of the small intestine. It has been known that dilated cardiomyopathy and ischemic coronary artery disease have become more frequent in patients with celiac disease. The aim of the study was to assess Tp-e interval and Tp-e/QT ratio in patients with celiac ...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:10.1016/j.rce.2017.09.001
更新日期:2017-11-01 00:00:00
abstract::Natriuretic peptides are a useful laboratory tool for the diagnosis, prognosis and treatment of patients with heart failure. Natriuretic peptides are used in various healthcare settings (consultations, emergency department, hospitalization, laboratory) and by various primary care and specialised professionals. However...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:10.1016/j.rce.2016.02.008
更新日期:2016-08-01 00:00:00
abstract::A retrospective study is presented of 19 patients who suffered Hypercortisolism who were examined by adrenal gammagraphy, echography, and CT scan in order to evaluate the usefulness of gammagraphy in the diagnostic approximation of this pathology. The gammagraphy findings had an excellent correlation with anatomopatho...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:
更新日期:1991-04-01 00:00:00
abstract:BACKGROUND:Adenosine deaminase (ADA) is a key enzyme in cellular immunity. It catalyses the reaction 2'deoxyadenosine to 2'deoxiinosine, a critical step in the production of essential metabolites for the synthesis of nucleic acids. Its main physiological activity occurs in T cells of lymphoid tissue. The advanced HIV i...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:
更新日期:1995-02-01 00:00:00
abstract::Type 2 diabetes mellitus is a major health problem with high prevalence, morbidity and mortality, and its medical treatment is growing in complexity due to patients' diverse clinical conditions. This article presents a consensus document by the Diabetes, Obesity and Nutrition Group of the Spanish Society of Internal M...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:10.1016/j.rce.2020.06.005
更新日期:2020-07-13 00:00:00
abstract::The cerebral trunk infection by Listeria monocytogenes is a very rare process, with only 24 described cases and only 2 in immunodepressed patients. We present a new case of cerebral trunk encephalitis caused by Listeria in a patient diagnosed of Polyarteritis nodosa on steroids and cyclophosamide treatment and fatal e...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:
更新日期:1990-11-01 00:00:00
abstract:OBJECTIVE:To demonstrate the validity of diurnal polysomnography for the diagnosis of obstructive sleep apnea syndrome (OSAS). METHODS:Twenty-five patients with suspect of OSAS were studied with two serial polysomnographic recordings: one during nighttime-nocturnal polysomnography (NPLS) and then a second polysomnogra...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:
更新日期:1998-06-01 00:00:00
abstract:INTRODUCTION:The role of glucose elevation above levels considered normal in non- diabetic patients with acute coronary syndromes (ACS) is not adequately defined. The aim of this study was to determine the association between serum glucose at admission and 1-year mortality in this type of patients. METHODS:We studied ...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:10.1157/13088586
更新日期:2006-06-01 00:00:00
abstract:BACKGROUND:Diagnosis of acute kidney injury (AKI) during acute decompensations of heart failure (ADHF) remain challenging. We analysed the incidence and prognosis of AKI, and the significance of small increases of creatinine, during ADHF and after stabilization. PATIENTS AND METHODS:Patients admitted for ADHF were pro...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:10.1016/j.rce.2019.11.008
更新日期:2019-12-24 00:00:00