Abstract:
OBJECTIVE:To study the evolution of antithrombin (AT) and plasma fibrinogen levels and of hematologic values among women in child-bearing age on treatment with the new hormonal oral contraceptives (HOC): in microdose, ultramicrodose and Diane-35. METHOD:Retrospective review of 100 randomized cases out of a total registry of 1,245 clinical records. RESULTS:The mean age in our series was 23.4 years (range: 18-39 years). The mean study time was 3.3 years (range: 1-5 years). During the study period, there was not a single woman with an AT lower than 70%. There were no significant changes at the end of the study period regarding AT, plasma fibrinogen, hematocrit, hemoglobin, prothrombin activity and activated partial thromboplastin time. A significant decrease was observed for platelet count (246,113 5,842 vs. 215,636 4,383 platelets/mm3; p = 0.003). There was not a single case of thrombocytopenia registered. No relevant differences were observed between the treatment groups with microdosaged, ultramicrodosaged and Diane-35. CONCLUSIONS:At mid-term (3.3 years), the new HOC (in microdose, ultramicrodose and Diane-35), do not cause significant changes in AT, plasma fibrinogen, hematocrit, hemoglobin, prothrombin activity and activated partial thromboplastin time. In our series, a moderate but significant decrease in the platelet count was observed but there were no cases of thrombocytopenia. The effect of the different new HOC on the studied parameters was similar.
journal_name
Rev Clin Espjournal_title
Revista clinica espanolaauthors
Calvo Romero JM,Lima Rodríguez EM,Peinado Rodríguez MT,Bureo Dacal P,Pérez Miranda Mdoi
10.1016/s0014-2565(01)70954-xkeywords:
subject
Has Abstractpub_date
2001-12-01 00:00:00pages
701-3issue
12eissn
0014-2565issn
1578-1860pii
13025168journal_volume
201pub_type
杂志文章abstract::We here present the case of a patient who starts with a progressive vision loss, observing in the radiologic exam herniation of optic chiasma in a primary empty sella turcica. Based on this case, we have performed a review of this clinical picture and point out the most important aspects in the literature. ...
journal_title:Revista clinica espanola
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abstract::Amongst 1.202 genital samples studied, the microscopic exam revealed in 179 (14.8%) cases flora compatible with bacterial vaginitis. Of these 179 samples, Mobiluncus SP was observed in 35 (19.6%) using Gram staining and in 18 (10.1%) this microorganism was isolated in agar RLK and anaerobic atmosphere. Using biochemic...
journal_title:Revista clinica espanola
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journal_title:Revista clinica espanola
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journal_title:Revista clinica espanola
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journal_title:Revista clinica espanola
pub_type: 杂志文章,评审
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journal_title:Revista clinica espanola
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journal_title:Revista clinica espanola
pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Revista clinica espanola
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doi:
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pub_type: 杂志文章
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journal_title:Revista clinica espanola
pub_type: 杂志文章,评审
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journal_title:Revista clinica espanola
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journal_title:Revista clinica espanola
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doi:
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journal_title:Revista clinica espanola
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journal_title:Revista clinica espanola
pub_type: 杂志文章,评审
doi:
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journal_title:Revista clinica espanola
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journal_title:Revista clinica espanola
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doi:
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journal_title:Revista clinica espanola
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journal_title:Revista clinica espanola
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journal_title:Revista clinica espanola
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更新日期:1990-04-01 00:00:00
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journal_title:Revista clinica espanola
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更新日期:1997-03-01 00:00:00
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journal_title:Revista clinica espanola
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