Abstract：
OBJECTIVE:To summarise the evidence on interventions aimed at optimising the drug treatment of hospitalised elderly patients. MATERIAL AND METHODS:We conducted a search in the main medical literature databases, selecting prospective studies of hospitalised patients older than 65 years who underwent interventions aimed at optimising drug treatment, decreasing polypharmacy and improving the medication appropriateness, health outcomes and exploitation of the healthcare system. RESULTS:We selected 18 studies whose interventions consisted of medication reviews, detection of predefined drugs as potentially inappropriate for the elderly, counselling from a specialised geriatric team, the use of a computer support system for prescriptions and specific training for the nursing team. Up to 14 studies assessed the medication appropriateness, 13 of which showed an improvement in one or more of the parameters. Seven studies measured the impact of the intervention on polypharmacy, but only one improved the outcomes compared with the control. Seven other studies analysed mortality, but none of them showed a reduction in that rate. Only 1 of 6 studies showed a reduction in the number of hospital readmissions, and 1 of 4 studies showed a reduction in the number of emergency department visits. CONCLUSIONS:Despite the heterogeneity of the analysed interventions and variables, we obtained better results in the process variables (especially in medication appropriateness) than in those that measured health outcomes, which had greater variability.
journal_name
Rev Clin Espjournal_title
Revista clinica espanolaauthors
Gutiérrez Valencia M,Martínez Velilla N,Lacalle Fabo E,Beobide Telleria I,Larrayoz Sola B,Tosato Mdoi
10.1016/j.rce.2016.01.005subject
Has Abstractpub_date
2016-05-01 00:00:00pages
205-21issue
4eissn
0014-2565issn
1578-1860pii
S0014-2565(16)00008-4journal_volume
216pub_type
杂志文章abstract：UNLABELLED:The increase in the mean populational age has increased the number of elderly people eligible for cardiac surgery. The aortic pathology represents the most common valvular pathology, mainly of degenerative etiology. The efficiency of the aortic valve replacement in people aged over 75 years was studied, with...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1998-05-01 00:00:00
abstract：:Basing heart failure (HF) classification on the echocardiographic values of left ventricular ejection fraction (LVEF) has been useful in defining two sub-types of HF: HF with reduced LVEF and HF with preserved LVEF. A new category has recently been defined: HF with midrange LVEF (40-49%). When current information is t...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2017.01.013
更新日期：2017-01-01 00:00:00
abstract：BACKGROUND:The presence of surface antigen of hepatitis B (HBsAg) virus in serum from recently vaccinated adults has been scarcely investigated. In this work, after the detection by chance of seven HBsAg-positive patients on hemodialysis who reported recent hepatitis B vaccination, a prospective study was undertaken to...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1999-04-01 00:00:00
abstract：:A case of diffuse mediastinal lipomatosis (ML) is described, associated to exogenous obesity, infrequent entity, which is comprehended within the causes which can cause mediastinal broadening. The clinical characteristics of our observation and the general aspects of interest are reviewed for this type of mediastinal ...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：
更新日期：1993-04-01 00:00:00
abstract：BACKGROUND:Fractures are the clinical complication of osteoporosis. There are no previous studies that describe the prevalence of vertebral fractures (VF) in patients admitted into a hospital due to a hip fracture (HF). OBJECTIVE:To study the prevalence of vertebral fractures in elderly women in the moment of their ad...
journal_title：Revista clinica espanola
pub_type： 杂志文章,多中心研究
doi：10.1157/13109839
更新日期：2007-10-01 00:00:00
abstract：:In order to assess the bacteriology of bronchial secretion samples, 40 patients in the intensive care unit who had developed fever and pulmonary infiltrates during mechanical ventilation have been studied. In each patient bronchial secretion samples were obtained by a double lumen distally-plugged telescopic catheter ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1989-02-01 00:00:00
abstract：:Cystic neoplasms of the pancreas make up a group of uncommon tumors. Their relevance lies upon their favorable prognosis after resection and the fact of being commonly mistaken with pseudocysts. Based on five patients treated at our hospital in the last few years we make an update review of the literature on these tum...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：
更新日期：1999-05-01 00:00:00
abstract：INTRODUCTION:Obesity is a chronic, complex and multifactorial metabolic disease involved in the development of chronic noncommunicable diseases such as type 2 diabetes mellitus, cardiovascular disease and cancer. The care of individuals with obesity is an essential part of the holistic approach provided by internal med...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2020.06.008
更新日期：2020-07-25 00:00:00
abstract：:Fourteen cases are revised of bronchiolalveolar carcinoma (BAC) diagnosed in our institution from 1980 to 1992. The time interval from clinical manifestations to diagnosis was 5.13 +/- 6.01 months. The incidence of smokers in the population was 42.8%. Clinical findings were non-specific, except in three cases, consist...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1994-12-01 00:00:00
abstract：:A case of gastroenteritis due to Giardia lamblia with severe dehydration and complicated with arterial thrombosis, accompanied by eosinophilia and increased serum IgE levels, is presented. The relationship between Giardia and eosinophilia and allergic manifestations is discussed as well as its pathogenesis. ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1990-06-01 00:00:00
abstract：OBJECTIVE:Although the genetic component in colorectal carcinoma (CRC) is well established, some environmental factors, mainly dietary, can favor its development. The objective of this study is to evaluate the relationship between daily consumption of specific food groups and development of CRC. METHODS:We carried out...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13063526
更新日期：2004-07-01 00:00:00
abstract：:We report the clinical, radiological and microbiological features of ten patients diagnosed of pyogenic sacroiliitis in an Internal Medicine Department during a 13 years period. Clinical signs and radiological or scintigraphical findings were present in every case. Staphylococcus aureus was isolated in blood cultures ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1993-10-01 00:00:00
abstract：:A study was carried out during five months in La Paz Hospital with the objective to know the proportion of admissions due to an adverse reaction to pharmaceutical drugs (RAM) or due to an acute drug intoxication. For this purpose the reports of all patients seen at the Medical Emergency Room were analyzed on a daily b...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：:Type 2 diabetes mellitus is a major health problem with high prevalence, morbidity and mortality, and its medical treatment is growing in complexity due to patients' diverse clinical conditions. This article presents a consensus document by the Diabetes, Obesity and Nutrition Group of the Spanish Society of Internal M...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2020.06.005
更新日期：2020-07-13 00:00:00
abstract：:Two cases of confirmed tuberculous Addison disease, with an increase in size of the adrenal glands are presented. One patient presented also a renal adenocarcinoma; this association is very rare given the small frequency of these diseases. Based on these two cases we emphasize the utility of puncture aspiration with a...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1989-12-01 00:00:00
abstract：:The watermelon stomach is a vascular malformation at the gastric antrum which is responsible for chronic bleeding. We report here nine patients (5 females and 4 males) referred to our Department from December 1990 to May 1995 with ferropenic anemia resulting from chronic gastrointestinal bleeding and with the diagnosi...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1996-05-01 00:00:00
abstract：:The clinical features of 30 patients with carcinomatous meningitis caused by solid tumors are reported. The most common originating sites of tumors were lung (12 cases) and breast (9 cases). Headache was the most common presenting symptom and there was involvement in more than one level of neuro-axis in 53% of cases. ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1994-07-01 00:00:00
abstract：:Correct functioning of the Ethics Committee (EC) guarantees respect to the rights of the subjects participating in clinical research. The European transposition of the clinical trial guidelines by the Royal Decree (RD) 223/2004 February 6 speeds up and simplifies the administrative procedures for the authorization of ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13079764
更新日期：2005-10-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:The pleural fluid/serum cholinesterase ratio (PF/S) is the most efficient parameter to differentiate transudates from exudates. The objective of this study was to evaluate whether its determination might yield additional diagnostic information in pleural exudates. MATERIALS AND METHODS:A tota...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1997-06-01 00:00:00
abstract：:Chronic obstructive pulmonary disease (COPD) encompasses a group of diseases characterized by chronic airway obstruction. This broad diagnostic umbrella includes several clinical phenotypes that overlap and respond differently to each type of therapeutic intervention. Roflumilast is a drug belonging to the new therape...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：10.1016/S0014-2565(11)70008-X
更新日期：2011-03-01 00:00:00
abstract：:Ogilvie's syndrome (OS) is a clinical condiction with the symptoms, signs and radiological appearances of acute bowell obstruction but without any apparent mechanical cause. Diagnosis and treatment are often delayed and many patients are still inappropriately managed which in turn results in an increase in morbidity a...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1995-11-01 00:00:00
abstract：BACKGROUND:The RS3PE syndrome is a recently described uncommon disorder in the elderly patient; in the initial reports, it was characterized by an excellent prognosis with total remission. In contrast with rheumatoid arthritis and polymyalgia rheumatic, it has been related to HLA B7. Further works have questioned its b...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1999-12-01 00:00:00
abstract：OBJECTIVE:To know the rate of occurrence of monoclonal bands in a clinical laboratory as an estimate of monoclonal gammopathy incidence, and to detect the proportion of these bands in which an explicit clinical diagnosis or follow-up request is not established. Other objectives are to describe its distribution and the ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13075569
更新日期：2005-05-01 00:00:00
abstract：:The clinical features of seven patients with persistent hiccup are reported. Hiccup did not respond to the usual therapies and resolved with baclofen. The administration guidelines and secondary effects are discussed. The authors suggest baclofen should be considered the drug of choice for treating persistent hiccup. ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1996-12-01 00:00:00
abstract：:In this clinical observation, we make a small summary of the current state of pharmacological treatment of obesity. The interest in the use of drugs in the treatment of obesity has grown in recent years, upon our knowledge of the biological basis of obesity having increased, and also because non-pharmacological treatm...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13074165
更新日期：2005-04-01 00:00:00
abstract：:In order to assess factors associated with spontaneous pneumothorax (SP), mainly climatic changes, a prospective study was undertaken of 62 SP episodes among patients admitted to our hospital during a two-year period, from January 1994 to January 1996. Atmospheric pressure (AP) changes were analyzed, with daily record...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/s0014-2565(02)70990-9
更新日期：2002-02-01 00:00:00
abstract：:Thirty-nine percent (33/83) of patients in this study present affective disorders in the chronic phase of ischemic cerebral vascular disease (ICV). The incidence of depression reaches its maximum in atherothrombotic infarcts (52%, 15/29) and in infarcts of cardiac embolic origin (71%, 5/7), and its minimum in lacunar ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1990-10-01 00:00:00
abstract：:BACKGROUND. In 1997, The Fourth International Workshop-Conference on Gestational Diabetes Mellitus (GDM) recommended the use of Carpenter and Coustan diagnostic criteria instead of those of Sullivan and Mahan used until then. The objective of this work was to study the incidence of GDM in the southeast Madrid area by ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/s0014-2565(02)71008-4
更新日期：2002-03-01 00:00:00
abstract：BACKGROUND:Sarcopenia is characterized by the loss of skeletal muscle mass and strength and represents a risk factor for frailty, loss of independence and physical disabilities. This study aimed to assess the prevalence of sarcopenia in a population of patients admitted to a media and long-stay unit. PATIENTS AND METH...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2014.02.018
更新日期：2014-08-01 00:00:00
abstract：OBJECTIVE:To identify overuse (diagnostic, therapeutic and self-care practices that represent risks that outweigh the potential benefits) in patients with atrial fibrillation. METHOD:The study was based on qualitative research techniques. Using the "Metaplan" technique, we identified and ordered potentially inappropri...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2017.02.014
更新日期：2017-05-01 00:00:00
