Abstract：
:The cerebral ganglia of the freshwater snail Lymnaea stagnalis contain two clusters of neurosecretory Caudo-Dorsal Cells (CDC). These cells produce a neurohormone which stimulates ovulation. Ganglion transplantation and quantitative electron microscopy show that neuronal isolation of the cerebral ganglia complex (CCC) results in an activation of the CDC. It was, therefore, concluded that the CDC are controlled by an inhibitory neuronal input originating outside the cerebral ganglia. Ultrastructural studies on synaptic degeneration in the CCC suggest that this input reaches the CDC via a special type of synapse-like structure, the type C-SLS. Furthermore, transplantation of CCC into acceptor snails leads to a reduced release and an increased intracellular brekdown of neurohormone in the CDC of the nervous system of the acceptors. It is supposed that these phenomena are caused by the release of an (unknown) factor from the transplanted CCC. Special attention was given to the formation and degradation of a peculiar type of neurohormone granule, the large electron dense granule. The physiological significance of the neuronal and non-neuronal control mechanisms which regulate CDC activity is discussed.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Roubos EWdoi
10.1007/BF00219720subject
Has Abstractpub_date
1976-04-28 00:00:00pages
11-31issue
1eissn
0302-766Xissn
1432-0878journal_volume
168pub_type
杂志文章abstract：:Research in mammals has demonstrated a variety of regulatory effects of vasopressin and oxytocin on endocrine functions of the anterior pituitary gland. Less evidence is available regarding the hypophysiotropic action of arginine vasotocin (AVT) comprising vasopressic and oxytocic activities in birds. Some hypophysiot...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-008-0636-2
更新日期：2008-08-01 00:00:00
abstract：:The pattern of innervation on individual iliotibialis muscle fibres from axolotl (Ambystoma mexicanum) has been investigated histologically and electrophysiologically. These polyneural fibres were found to be innervated on average at five end plate sites. The sites were distributed irregularly along each fibre. Averag...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219663
更新日期：1978-01-09 00:00:00
abstract：:Cytochemical methods for the demonstration of p-nitrophenylphosphatase (p-NPPase) at the electron-microscopic level were applied to avian osteoclasts to elucidate some of the functional differences among ruffled border, other membrane systems, and cellular organelles. The localization of p-NPPase activity occurred in ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00218381
更新日期：1986-01-01 00:00:00
abstract：:The processes involved in the regulation of bone cell metabolism are complex, including those implicated in bone cell coupling. This study was undertaken to develop a model that would permit real-time interaction between osteoclastic cells and osteoblasts in vitro. Osteogenic bone marrow stromal cells were isolated fr...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051160
更新日期：1998-10-01 00:00:00
abstract：:Tissue lectins appear to be involved in a broad range of physiological processes, as reflected for the members of the family of galectins by referring to them as adhesion/growth-regulatory effectors. In order to clarify the significance of galectin presence, key challenges are to define their binding partners and the ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-018-2931-x
更新日期：2019-03-01 00:00:00
abstract：:The number, size and structure of tendon organs were examined in leg muscles of the rat 3-19 weeks after de-efferentation performed in newborn animals by removal of the lumbosacral spinal cord. After this operation, tendon organs differentiated and grew in disused muscles and were innervated by primary sensory neurons...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00214645
更新日期：1985-01-01 00:00:00
abstract：:Interstitial cells of Cajal (ICCs) are believed to be a major element in generating the spontaneous rhythm of the gastrointestinal tract. A prominent problem in the study of these cells has been the difficulty in observing them in intact tissues. We used the lipophilic dye DiI to stain ICCs in the submucosal-circular ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051058
更新日期：1998-05-01 00:00:00
abstract：:Long-non-coding RNA (lncRNA) regulates gene expression through transcriptional and epigenetic regulation as well as alternative splicing in the nucleus. In addition, regulation is achieved at the levels of mRNA translation, storage and degradation in the cytoplasm. During recent years, several studies have described t...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-014-1885-x
更新日期：2014-06-01 00:00:00
abstract：:The position, structure and function of the valves within the lateral sinus of the medical leech, Hirudo medicinalis, are described on the basis of vital, light- and electron microscopy. In this species the valvular apparatus consists of multiple elongated fir cone-shaped fibrous villi surrounding the orifices of the ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00399522
更新日期：1976-09-20 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00218939
更新日期：1987-12-01 00:00:00
abstract：:Noses are extremely sophisticated chemical detectors allowing animals to use scents to interpret and navigate their environments. Odor detection starts with the activation of odorant receptors (ORs), expressed in mature olfactory sensory neurons (OSNs) populating the olfactory mucosa. Different odorants, or different ...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-020-03327-1
更新日期：2021-01-06 00:00:00
abstract：:We present an experimental method allowing the production of three-dimensional organ-like structures, namely microtissues (MTs), in vitro without the need for exogenous extracellular matrix (ECM) or growth factors. Submandibular salivary glands (embryonic day ED14), kidneys (ED13) and lungs (ED13) were harvested from ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-016-2487-6
更新日期：2016-12-01 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00215699
更新日期：1982-01-01 00:00:00
abstract：:The fine structure of spermatids has been examined in Calliactis, Protanthea, Gonactinia and Parazoanthus (Cnidaria, Anthozoa). The sperm cells are relatively simple and lack distinct acrosomes. Their nuclei, spherical in the zoanthid, in the actinians are slendertipped cones. Condensation of the chromatin is interpre...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00222065
更新日期：1975-01-01 00:00:00
abstract：:An immunohistochemical study for islet amyloid polypeptide (IAPP) was made on the gastrointestinal (GI) tract and pancreas of man and rat, using antisera raised against a synthetic peptide of C-terminal human IAPP (24-37) and a synthetic peptide of rat IAPP (18-37). A large number of IAPP-immunoreactive cells were fou...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00305236
更新日期：1990-12-01 00:00:00
abstract：:The distributions within the coeliac ganglion of different chemically coded subgroups of noradrenaline neurons, and the relationships between these neurons and nerve fibres projecting to the ganglion from the intestine, have been assessed quantitatively by use of an immunohistochemical double-staining method. Noradren...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00218395
更新日期：1986-01-01 00:00:00
abstract：:The LIM homeodomain transcription factor Lmx1a shows a dynamic expression in the developing mouse ear that stabilizes in the non-sensory epithelium. Previous work showed that Lmx1a functional null mutants have an additional sensory hair cell patch in the posterior wall of a cochlear duct and have a mix of vestibular a...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-019-03163-y
更新日期：2020-06-01 00:00:00
abstract：:The mechanism of cell death which occurs during Chagas' cardiopathy is disputed. To address this issue we analyzed the molecular pathways implicated in the death of cardiomyocytes during T. cruzi invasion and found that they undergo apoptosis during both in vitro and in vivo infections. However, the death rates and on...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-003-0782-5
更新日期：2003-11-01 00:00:00
abstract：:Although the secretory products of the hypothalamo-neurohypophyseal system are not glycoproteins, synthesis and migration of these macromolecules occur within its secretory neurons. After being labeled with 3H-fucose in the Golgi apparatus, newly synthesized glycoproteins migrate to secretion granules, lysosomes and t...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00234755
更新日期：1980-01-01 00:00:00
abstract：:Transmission electron microscopy was used to study the effects of proteolytic enzymes (collagenase, trypsin, clostripain), the calcium chelator ethyleneglycol-bis-(beta-aminoethyl ether) N,N,N',N'-tetraacetic acid (EGTA), and the calcium ionophore A 23187 on substrate adhesion and fine structure of chondrocytes and fi...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00228443
更新日期：1984-01-01 00:00:00
abstract：:In fresh-water turtles, the bridge connecting the proximal and caudal stumps of transected spinal cords consists of regenerating axons running through a glial cellular matrix. To understand the process leading to the generation of the scaffold bridging the lesion, we analyzed the mitotic activity triggered by spinal i...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-011-1173-y
更新日期：2011-06-01 00:00:00
abstract：:Macrophages are present throughout the anterior pituitary gland. However, the features and function of macrophages in the gland are poorly understood. Recent studies have indicated that there are two main macrophage classes: M1 (classically activated) and M2 (alternatively activated). In this study, we examine whether...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-016-2564-x
更新日期：2017-05-01 00:00:00
abstract：:In the stalk-eyed fly Cyrtodiopsis whitei (Diopsidae; Diptera), the relatively long optic nerve develops within the tight lumen of a very short eyestalk. Axonal growth is generally considered in terms of path finding, selective fasciculation, and towing. Physical forces that are necessary for axon lengthening are gene...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-005-1142-4
更新日期：2005-09-01 00:00:00
abstract：:We compare the ultrastructure of the gerbil sublingual gland as seen after cryofixation followed by substitution with osmium tetroxide, with the more familiar appearance of material processed by glutaraldehyde-osmium chemical fixation. After primary cryofixation of fresh salivary glands, the nuclei of the mucous cells...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219075
更新日期：1987-11-01 00:00:00
abstract：:Growing numbers of translational genomics studies are based on the highly efficient and versatile zebrafish (Danio rerio) vertebrate model. The increasing types of zebrafish models have improved our understanding of inherited kidney diseases, since they not only display pathophysiological changes but also give us the ...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-017-2593-0
更新日期：2017-07-01 00:00:00
abstract：:In the corpuscles of Stannius of sticklebacks and eels two cell types are described of presumably endocrine nature. The predominating type, comparable to the cells observed in other species, responds to variation in calcium content of the medium and possibly produces a hypocalcemic hormone. The second cell type is unr...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219163
更新日期：1975-06-09 00:00:00
abstract：:Granular hormone-producing cells and agranular cells (stellate cells, including giant and pericavitary cells) were electron microscopically studied in the hypophysis of the small spotted dogfish (Scyllium canicula) up to several months after hatching. Comparisons of results obtained in embryos, newly-hatched fish and ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00221607
更新日期：1978-10-06 00:00:00
abstract：:Fixed cerebral vesicles of mouse foetuses were fractured and examined with the scanning electron microscope. This method provides a study of the three dimensional developmental features of the pseudostratified columnar epithelium up to the formation of the early cortex plate. Matrix cells are a cell population of homo...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219466
更新日期：1975-11-12 00:00:00
abstract：:The retina of the distal and proximal lens-bearing complex ocelli are composed of pigmented sensory cells and long pigmented cells. A ciliary sheath from each sensory cell, together with the processes of long pigmented cells, extends through the vitreous layer as far as the capsule that envelops the lens. Each ciliary...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219415
更新日期：1976-07-30 00:00:00
abstract：:The elaboration and distribution of newly formed proteins in the striated muscle of 21-day-old mice were investigated by quantitative radioautography at intervals between 2 and 240 min after intravenous injection of tritiated leucine. In radioautographs, the localization and the relative label concentration were compa...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00209040
更新日期：1978-10-17 00:00:00
