Abstract：
:We performed a comparative study of four subfamilies of olfactory receptor genes first identified in the dog to assess changes in the gene family during mammalian evolution, and to begin linking the dog genetic map to that of humans. The human subfamilies were localized to chromosomes 7, 11, and 19. The two subfamilies that were tightly linked in the dog genome were also tightly linked in the human genome. The four subfamilies were compared in human (primate), horse (perissodactyl), and a variety of artiodactyls and carnivores. Some changes in gene number were detected, but overall subfamily size appeared to have been established before the divergence of these mammals 60-100 million years ago.
journal_name
Geneticsjournal_title
Geneticsauthors
Issel-Tarver L,Rine Jsubject
Has Abstractpub_date
1997-01-01 00:00:00pages
185-95issue
1eissn
0016-6731issn
1943-2631journal_volume
145pub_type
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