Abstract：
:A coalescent theory for a sample of DNA sequences from a partially selfing diploid population and an algorithm for simulating such samples are developed in this article. Approximate formulas are given for the expectation and the variance of the number of segregating sites in a sample of k sequences from n individuals. Several new estimators of the important parameters theta = 4N mu and the selfing rate s, where N and mu are, respectively, the effective population size and the mutation rate per sequence per generation, are proposed and their sampling properties are studied.
journal_name
Geneticsjournal_title
Geneticsauthors
Fu YXsubject
Has Abstractpub_date
1997-08-01 00:00:00pages
1489-99issue
4eissn
0016-6731issn
1943-2631journal_volume
146pub_type
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