Leptin: the weight-reducing plasma protein encoded by the obese gene.

Abstract:

:Leptin, the protein encoded by the recently cloned obese gene, has the properties of a hormone released by adipose tissue, regulating appetite and energy expenditure. Injected leptin reduces body weight and food intake in mice, and in obese, diabetic mice (with a mutated obese gene), it also reduces plasma insulin and glucose. Leptin release is stimulated by insulin; leptin appears to act on the hypothalamus by inhibiting the release of the neuropeptide Y.

journal_name

Nutr Rev

journal_title

Nutrition reviews

authors

Wolf G

doi

10.1111/j.1753-4887.1996.tb03878.x

subject

Has Abstract

pub_date

1996-03-01 00:00:00

pages

91-3

issue

3

eissn

0029-6643

issn

1753-4887

journal_volume

54

pub_type

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