Abstract：
CONTEXT:The ability to measure the gut microbiome led to a surge in understanding and knowledge of its role in health and disease. The diet is a source of fuel for and influencer of composition of the microbiome. OBJECTIVE:To assess the understanding of the interactions between nutrition and the gut microbiome in healthy adults. DATA SOURCES:PubMed and Google Scholar searches were conducted in March and August 2018 and were limited to the following: English, 2010-2018, healthy adults, and reviews. DATA EXTRACTION:A total of 86 articles were independently screened for duplicates and relevance, based on preidentified inclusion criteria. DATA ANALYSIS:Research has focused on dietary fiber - microbiota fuel. The benefits of fiber center on short-chain fatty acids, which are required by colonocytes, improve absorption, and reduce intestinal transit time. Contrastingly, protein promotes microbial protein metabolism and potentially harmful by-products that can stagnate in the gut. The microbiota utilize and produce micronutrients; the bidirectional relationship between micronutrition and the gut microbiome is emerging. CONCLUSIONS:Nutrition has profound effects on microbial composition, in turn affecting wide-ranging metabolic, hormonal, and neurological processes. There is no consensus on what defines a "healthy" gut microbiome. Future research must consider individual responses to diet.
journal_name
Nutr Revjournal_title
Nutrition reviewsauthors
Frame LA,Costa E,Jackson SAdoi
10.1093/nutrit/nuz106subject
Has Abstractpub_date
2020-10-01 00:00:00pages
798-812issue
10eissn
0029-6643issn
1753-4887pii
5811361journal_volume
78pub_type
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