IL-4 in schistosomiasis.

abstract：:An increased level of plasma corticosterone is one manifestation of severe environmental or physiologic stress. The stress response mediated by the hypothalamic-pituitary-adrenal axis is already known to suppress immunoglobulin production and to impair immune function, but there are few studies relating stress and pla...

journal_title：Experimental parasitology

authors： Santos CD,Prado JC Jr,Toldo MP,Levy AM,Franci CR,Caldeira JC

更新日期：2007-12-01 00:00:00

abstract：:The anthelmintic effects of plumbagin (PB, 5-hydroxy-2-methyl-1,4-naphthoquinone) and praziquantel (PZQ) against adult Schistosoma mansoni in vitro were compared by estimating the relative motility (RM) values, survival indices (SI) and alterations of the tegument of flukes incubated in M-199 medium containing 1, 10 a...

journal_title：Experimental parasitology

authors： Lorsuwannarat N,Saowakon N,Ramasoota P,Wanichanon C,Sobhon P

更新日期：2013-01-01 00:00:00

abstract：:Larvae of Rhinoestrus spp. (Diptera, Oestridae) infect nasal and sinus cavities of horses, causing a nasal myiasis characterized by severe respiratory distress. Presently, the diagnosis of horse nasal botfly relies on the observation of clinical signs, on the post mortem retrieval of larvae or on molecular assays perf...

journal_title：Experimental parasitology

authors： Milillo P,Traversa D,Elia G,Otranto D

更新日期：2010-04-01 00:00:00

abstract：:Trypanosoma cruzi is a rare example of an eukaryote that has genes for two threonine proteases: HslVU complex and 20S proteasome. HslVU is an ATP-dependent protease consisting of two multimeric components: the HslU ATPase and the HslV peptidase. In this study, we expressed and obtained specific antibodies to HslU and ...

journal_title：Experimental parasitology

authors： Barboza NR,Cardoso J,de Paula Lima CV,Soares MJ,Gradia DF,Hangai NS,Bahia MT,de Lana M,Krieger MA,Guerra de Sá R

更新日期：2012-02-01 00:00:00

abstract：:A murine model system was developed to study the induction and mechanism of protective immunity to L3 of Strongyloides stercoralis. L3 were implanted in BALB/cByJ mice in diffusion chambers constructed with 0.1- or 2.0-microns-pore-size membranes. Parasites survived equally well regardless or membrane type for 7 days,...

journal_title：Experimental parasitology

authors： Abraham D,Rotman HL,Haberstroh HF,Yutanawiboonchai W,Brigandi RA,Leon O,Nolan TJ,Schad GA

更新日期：1995-03-01 00:00:00

abstract：:Susceptible A/J and more resistant C57BL/6J mice were infected with Plasmodium chabaudi chabaudi 54X, P.c. chabaudi AS and Plasmodium chabaudi adami 408XZ. As expected, most C57BL/6J mice survived the infections with the different isolates. But in contrast to previous observations, not all A/J mice succumbed to infect...

journal_title：Experimental parasitology

authors： Hernandez-Valladares M,Naessens J,Nagda S,Musoke AJ,Rihet P,Ole-Moiyoi OK,Iraqi FA

更新日期：2004-11-01 00:00:00

abstract：:A rodent model of malaria, Plasmodium berghei was used to assess the antimalarial potential of dinitroaniline herbicides. Trifluralin, pendimethalin, oryzalin, and benfluralin were all active against P. berghei in vitro at, or close to, submicromolar concentrations, with a rank order of potency similar to that against...

journal_title：Experimental parasitology

authors： Dow GS,Armson A,Boddy MR,Itenge T,McCarthy D,Parkin JE,Thompson RC,Reynoldson JA

更新日期：2002-03-01 00:00:00

abstract：:Cardiac beta-adrenergic receptors' function was studied in the acute phase of Chagas' disease in mice reinfected with Trypanosoma cruzi Tulahuen strain (Tul) and with parasites isolated from an infected patient (SGO-Z12). Genetic characterization of SGO-Z12 isolates demonstrated that it belongs to the zimodeme Z12, on...

journal_title：Experimental parasitology

authors： Bustamante JM,Rivarola HW,Fernández AR,Enders JE,Ricardo F,d'Oro Gloria DL,Palma JA,Paglini-Oliva PA

更新日期：2003-03-01 00:00:00

abstract：:Proteins belonging to the serine protease inhibitor (serpin) superfamily play essential roles in many organisms. In arthropods these proteins are involved in innate immune system, morphogenesis and development. In mammals serpins regulate pathways that are essential to life such as blood coagulation, fibrinolysis, inf...

journal_title：Experimental parasitology

authors： Tirloni L,Seixas A,Mulenga A,Vaz Ida S Jr,Termignoni C

更新日期：2014-02-01 00:00:00

abstract：:Eosinophilia in blood and tissues has been strongly associated with helminth infections for over a century. In vivo depletion of IL-5, a cytokine crucially involved in eosinophilopoiesis with an antibody or through genetic manipulation, reproducibly abrogates helminth-induced eosinophilia, but renders mice permissive ...

journal_title：Experimental parasitology

authors： Ramalingam T,Ganley-Leal L,Porte P,Rajan TV

更新日期：2003-10-01 00:00:00

abstract：:Typically, antimicrobial peptides (AMPs) are short positive charged peptides serving a key role in innate immunity as well as antimicrobial activity. Discovering novel therapeutic agents is considered as an undeniable demand due to increasing microbial species with antibiotic resistance. In this direction, the unique ...

journal_title：Experimental parasitology

authors： Zahedifard F,Lee H,No JH,Salimi M,Seyed N,Asoodeh A,Rafati S

更新日期：2020-02-01 00:00:00

abstract：:Three membrane thermotropic transitions at 8, 20, and 40 degrees C have been detected in human red blood cells (RBC) by using spin-labeled stearic acids. Red blood cells infected in vitro by Plasmodium falciparum showed the disappearance of the 8 degrees C transition and a lowering of the 40 degrees C transition to 32...

journal_title：Experimental parasitology

authors： Forte T,Roca L

更新日期：1989-10-01 00:00:00

abstract：:Chemical acaricides, especially fipronil (active ingredient of Frontline®), are still the most effective method to control tick populations. In this study, the effectiveness of fipronil was assessed in semi-engorged females of the tick Rhipicephalus sanguineus. A protocol for an in vitro bioassay (AIT) was developed, ...

journal_title：Experimental parasitology

authors： de Oliveira PR,Bechara GH,Denardi SE,Pizano MA,Mathias MI

更新日期：2011-02-01 00:00:00

abstract：:The opossum Didelphis marsupialis is known to be among the most important wild reservoirs of Trypanosoma cruzi and one in which the trypanosome may go through both the usual vertebrate intracellular cycle in its tissues and an extracellular cycle in the lumen of its scent glands. The species is highly resistant to hea...

journal_title：Experimental parasitology

authors： Jansen AM,Leon L,Machado GM,da Silva MH,Souza-Leão SM,Deane MP

更新日期：1991-10-01 00:00:00

abstract：:Complement activation by protoscoleces of Echinococcus granulosus was studied by analyzing the damage to their tegumental membrane produced by incubation in both normal and hydatid human sera. The state of the apical tegumental membrane was evaluated by measuring the electric potential difference with microelectrodes....

journal_title：Experimental parasitology

authors： Ferreira AM,Trecu T,Reisin I

更新日期：1992-11-01 00:00:00

abstract：:Investigation of protease activities during the transformation of Trypanosoma cruzi epimastigotes into metacyclic trypomastigoes (metacyclo-genesis) revealed three major components with apparent molecular weights of 65, 52, and 40 kDa. The 65-kDa protease is a metacyclic trypomastigote stage-specific protease with an ...

journal_title：Experimental parasitology

authors： Bonaldo MC,d'Escoffier LN,Salles JM,Goldenberg S

更新日期：1991-07-01 00:00:00

abstract：:It is well known that Anopheles dirus is naturally refractory to rodent malaria parasite, Plasmodium yoelii, but the mechanism is still largely unknown. Here, we found that some P. yoelii taken into An. dirus could develop into oocysts, but oocysts were partially melanized at 7 days and completely melanized at 15 days...

journal_title：Experimental parasitology

authors： Wen-Yue X,Jian Z,Tao-Li Z,Fu-Sheng H,Jian-Hua D,Ying W,Zhong-Wen Q,Li-Sha X

更新日期：2007-08-01 00:00:00

abstract：:Toxoplasmosis is a widely distributed disease caused by the protozoan Toxoplasma gondii that is mainly transmitted orally. Once ingested, the parasite crosses the intestinal barrier to reach the blood and lymph systems to migrate to other regions of the host. The objective of this study was to evaluate the changes in ...

journal_title：Experimental parasitology

authors： Vicentino-Vieira SL,Nogueira de Melo Gde A,Biondaro Góis M,Martins Moreira N,de Araujo Pereira LG,de Almeida Araújo EJ,Garcia JL,de Mello Gonçales Sant'Ana D

更新日期：2015-09-01 00:00:00

abstract：:The swimming behavior of Poecilia vivipara was evaluated using an image analysis system comparing laboratory-reared uninfected fish before and after experimental infection with different intensities of cercariae of the trematode Acanthocollaritrema umbilicatum. Two experiments were performed, each with 30 fish which w...

journal_title：Experimental parasitology

authors： Santos EG,Cunha RA,Santos CP

更新日期：2011-02-01 00:00:00

abstract：:In order to examine the role of IFN-gamma, TNFRp55 and iNOS in inflammatory reaction during toxoplasmosis, IFN-gamma(-/-), TNFRp55(-/-) and iNOS(-/-) mice were experimentally infected with Toxoplasma gondii ME-49 strain. The organs of the mice were evaluated for histology and immunohistochemistry in detection of tissu...

journal_title：Experimental parasitology

authors： Silva NM,Vieira JC,Carneiro CM,Tafuri WL

更新日期：2009-09-01 00:00:00

abstract：:We report here the pre-mRNA 3' end processing machinery in Entamoeba histolytica. Comparative analysis of the putative sequences participating in the pre-mRNA 3' end processing of E. histolytica genes shows similitude and differences to those described for yeast and human transcripts. By a genomic survey, we identifie...

journal_title：Experimental parasitology

authors： López-Camarillo C,Orozco E,Marchat LA

更新日期：2005-07-01 00:00:00

abstract：:S(2) complex has been reported to have a direct antileishmanial effect. The possibility that the direct antileishmanial effect may be due to inhibition of key enzymes involved in glucose metabolism and/ or enzymes associated with virulence was investigated. Cell pellets were prepared from cultures of both axenic amast...

journal_title：Experimental parasitology

authors： Al-Mulla Hummadi YM,Al-Bashir NM,Najim RA

更新日期：2006-02-01 00:00:00

abstract：:Previous studies have shown that intradermally (ID) injected Brugia pahangi L3 s migrate through various tissues and into the lymphatics of gerbils in a distinct pattern. Excretory/secretory products (ES) produced at the time of invasion of B. pahangi are likely to be important in this early migration phase of the par...

journal_title：Experimental parasitology

authors： Zipperer GR,Arumugam S,Chirgwin SR,Coleman SU,Shakya KP,Klei TR

更新日期：2013-10-01 00:00:00

abstract：:Chagas disease is characterized by cardiac lesions and a high level of PGE2. Our objective was to investigate the role of PGE2 in cardiac lesions. BALB/c mice were infected with Trypanosoma cruzi (1x10(3) trypomastigote forms) and were treated daily with PBS, meloxicam (0.5 mg/kg) or etoricoxib (0.6 mg/kg). The animal...

journal_title：Experimental parasitology

authors： Abdalla GK,Faria GE,Silva KT,Castro EC,Reis MA,Michelin MA

更新日期：2008-04-01 00:00:00

abstract：:The stability of the gene encoding TSA417, a 72-kDa variant-specific surface protein (VSP) produced by trophozoites of Giardia intestinalis isolate WB-C6, was investigated in isolates of similar (Assemblage A / Group I) or distinct (Assemblage A / Group II) genotype. Using primers specific for the WB-C6 tsa417 gene, D...

journal_title：Experimental parasitology

authors： Ey PL,Darby JM

更新日期：1998-11-01 00:00:00

abstract：:A Schistosoma mansoni G-protein coupled receptor (SmGPCR) was previously cloned and shown to be activated by the biogenic amine, histamine. Here we report a first investigation of the receptor's subunit organization, tissue distribution and expression levels in different stages of the parasite. A polyclonal antibody w...

journal_title：Experimental parasitology

authors： El-Shehabi F,Vermeire JJ,Yoshino TP,Ribeiro P

更新日期：2009-05-01 00:00:00

abstract：:Malaria caused by the protozoan parasite Plasmodium falciparum, is a major health problem of the developing world. In the present study medicinal plants from Eastern Ghats of South India have been extracted with ethyl acetate and assayed for growth inhibition of asexual erythrocytic stages of chloroquine (CQ)-sensitiv...

journal_title：Experimental parasitology

authors： Kaushik NK,Bagavan A,Rahuman AA,Mohanakrishnan D,Kamaraj C,Elango G,Zahir AA,Sahal D

更新日期：2013-05-01 00:00:00

abstract：:Giardia lamblia is the most commonly detected parasite in the intestinal tract of humans and other mammals causing giardiasis. Giardia presents several cytoskeletal structures with microtubules as major components such as the ventral adhesive disk, eight flagella axonemes, the median body and funis. Many drugs have al...

journal_title：Experimental parasitology

authors： Mariante RM,Vancini RG,Melo AL,Benchimol M

更新日期：2005-05-01 00:00:00

abstract：:We here describe the novel finding that brain endothelial cells in vitro can stimulate the growth of Plasmodium falciparum through the production of low molecular weight growth factors. By using a conditioned medium approach, we show that the brain endothelial cells continued to release these factors over time. If thi...

journal_title：Experimental parasitology

authors： Khaw LT,Ball HJ,Mitchell AJ,Grau GE,Stocker R,Golenser J,Hunt NH

更新日期：2014-10-01 00:00:00

abstract：:Tapeworms Taenia solium and Taenia saginata are the causative agents of taeniasis/cysticercosis. These are diseases with high medical and veterinary importance due to their impact on public health and rural economy in tropical countries. The re-emergence of T. solium as a result of human migration, the economic burden...

journal_title：Experimental parasitology

authors： Solano D,Navarro JC,León-Reyes A,Benítez-Ortiz W,Rodríguez-Hidalgo R

更新日期：2016-12-01 00:00:00