Abstract：
:Changes in cell immunity made manifest by decreases in blood levels of CD4 T cells is the main indicator of progressing HIV infection. The decrease in these lymphocytes, as well as in the CD4/CD8 index and increases in suppressant or cytotoxic CD8 cells can be detected in bronchoalveolar (BAL) lung samples. It is not clear whether the high incidence of respiratory system diseases in HIV patients stems from local or systemic immune changes. The aim of this study was to compare changes in the systemic cell immunity studied in samples of peripheral blood with changes detected in BAL samples from HIV patients with acute respiratory disease. We studied 42 patients in the advanced stages of AIDS (C3 by Centers for Disease Control classification) who were hospitalized for acute respiratory disease and who underwent diagnostic fiberoptic bronchoscopy and BAL. Cell counts and lymphocyte populations were analyzed by flow cytometry in samples of peripheral blood and BAL. The percentage of CD4 lymphocytes and the CD4/CD8 index were lower in BAL, particularly in patients with blood CD4 levels below 12% of the total T cell population, or at a level of 20 CD4 cells/microliters. Changes in cell immunity in patients with advanced HIV infection (C3 classification) and acute respiratory disease are more manifest locally in the lung than peripherally in blood. Lung depletion of CD4 T cells in the lung can be predicted based on blood levels.
journal_name
Arch Bronconeumoljournal_title
Archivos de bronconeumologiaauthors
Fernández E,León P,Blanquer R,Marín M,Artero A,Pinilla Adoi
10.1016/s0300-2896(15)30751-1subject
Has Abstractpub_date
1996-06-01 00:00:00pages
271-4issue
6eissn
0300-2896issn
1579-2129pii
S0300-2896(15)30751-1journal_volume
32pub_type
杂志文章abstract：:Assessment of alpha 1-antitrypsin replacement therapy (AAT) for emphysema. Patient characteristics were analyzed along with the possible side effects of the treatment and its efficacy in maintaining appropriate AAT blood levels. Lung function changes were also studied. The treatment protocol began with 4 weekly intrav...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/s0300-2896(15)30997-2
更新日期：1994-12-01 00:00:00
abstract：INTRODUCTION:In recent years, there has been debate regarding the diagnostic accuracy of computed tomography (CT) in the identification of lung metastases and the need for lung palpation to determine the number of metastatic nodules. The aim of this study was to determine in which patients the CT scan was more effectiv...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/j.arbres.2013.05.006
更新日期：2013-12-01 00:00:00
abstract：OBJECTIVE:Workers in shoe manufacturing have been reported to be at a greater relative risk for bronchogenic carcinoma. Given the implications for our practice setting, we carried out a study to a) clarify whether working in shoe manufacturing is a risk factor for lung cancer and b) detect histological differences betw...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/s1579-2129(06)60426-6
更新日期：2005-04-01 00:00:00
abstract：:Epidemiological data suggest that sleep apnea-hypopnea syndrome (SAHS) is independently associated with the development of insulin resistance and glucose intolerance. Moreover, despite significant methodological limitations, some studies report a high prevalence of SAHS in patients with type 2 diabetes mellitus (DM2)....
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,评审
doi：10.1016/j.arbres.2014.06.017
更新日期：2015-03-01 00:00:00
abstract：OBJECTIVE:Mortality due to lung cancer in Spain is increasing continuously. The aim of the present study was to collect information on the hospital incidence of lung cancer, as well as information on clinical management, in different regions of Spain. MATERIAL AND METHODS:A prospective observational study of patients ...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,多中心研究
doi：
更新日期：2006-09-01 00:00:00
abstract：:We analyze the result of using a pneumological rapid-attention facility for diagnosis and immediate treatment of patients with respiratory symptoms arriving at the emergency room of University Hospital Virgen del Rocío in Seville (Spain). In the first six months the outpatient service saw 321 patients (male/female rat...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：
更新日期：1997-06-01 00:00:00
abstract：INTRODUCTION:Obesity is associated with 2 closely related respiratory diseases: obesity hypoventilation syndrome (OHS) and obstructive sleep apnea-hypopnea syndrome (OSAHS). It has been shown that noninvasive ventilation during sleep produces clinical and functional improvement in these patients. The long-term survival...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/j.arbres.2014.02.015
更新日期：2015-02-01 00:00:00
abstract：OBJECTIVE:Localized fibrous tumors of the pleura are rare. We report 7 cases and review the literature in order to define the range of clinical characteristics of these tumors, treatment options, and prognosis. METHODS:A retrospective review of 7 cases treated between 1997 and 2003, focusing on clinical presentation, ...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/s1579-2129(06)60311-x
更新日期：2004-07-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Asthma's great impact on public health stems from its chronicity and to high prevalence among all age groups and both sexes. To estimate the appropriateness of treatment and management of asthma in Spain during the period of 1991 and 1992, we analyzed data from the European Community Respirato...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/s0300-2896(15)30259-3
更新日期：1999-05-01 00:00:00
abstract：OBJECTIVE:To compare the effects of a simple home pulmonary rehabilitation program and an intensive hospital-based program in terms of the exercise tolerance and health-related quality of life (HRQL) of patients with severe chronic obstructive pulmonary disease (COPD). PATIENTS AND METHODS:Patients in this prospective...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,多中心研究,随机对照试验
doi：
更新日期：2008-10-01 00:00:00
abstract：:Atrophy and weakness of the respiratory and peripheral muscles is a common problem in the intensive care unit (ICU). It is difficult to diagnose, particularly in the early stages of critical disease. Consequently, many cases are detected only in advanced stages, for example, when difficulties in mechanical ventilation...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,评审
doi：10.1016/j.arbres.2018.09.002
更新日期：2019-05-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:In a split-night study, the first part consists of standard polysomnography (PSG) for the diagnosis of obstructive sleep apnea syndrome while the second part is used to establish a suitable level of continuous positive airway pressure. The aim of our study was to compare the sleep and respirato...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/s1579-2129(08)60002-6
更新日期：2008-01-01 00:00:00
abstract：:In the last few years, a large number of studies on mortality in patients with chronic obstructive pulmonary disease (COPD) have been published. All these studies aim to provide knowledge with the ultimate aim of reducing the increasing number of deaths. However, these studies also introduce subtle methodological fact...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,评审
doi：
更新日期：2008-01-01 00:00:00
abstract：:We assessed the clinicopathological features of solitary fibrous tumors of the pleura in a case series comprising 30 patients (20 women, 66.6%) with a mean age of 58.39 years. Forty-five percent of the cases were asymptomatic. In 70% of the cases the tumors arose in the visceral pleura. Twenty percent presented multip...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,评审
doi：10.1016/s1579-2129(06)60124-9
更新日期：2006-02-01 00:00:00
abstract：:Chronic obstructive pulmonary disease (COPD) is a multidimensional disease with wide phenotypic heterogeneity that is not adequately reflected by forced expiratory volume in 1 second (FEV(1)). Assessment of patients with COPD requires analysis of multiple variables that encompass respiratory and extrapulmonary involve...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/S0300-2896(09)72953-9
更新日期：2009-01-01 00:00:00
abstract：OBJECTIVE:Certain sporting activities may trigger asthma exacerbations of varying intensity in children. Such exacerbations may lead to limitations in and rejection of such activities. During school hours, teachers are in a good position to observe these phenomena. The aim of the present study was to evaluate the shutt...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/s1579-2129(06)60588-0
更新日期：2006-11-01 00:00:00
abstract：INTRODUCTION:The objective of this analysis was the evaluation of a new national circuit used for diagnosing alpha1 antitrypsin deficiency (AATD) based on multiplex technology using online registration and mail posted samples from dried blood spots (DBS) and buccal swabs. METHODS:This is an observational, ongoing stud...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/j.arbres.2020.04.014
更新日期：2021-01-01 00:00:00
abstract：:Mucormycosis is an opportunistic mycotic infection, the frequency of pulmonary infection is 22% and the associated mortality rates were 83% for pulmonary. We present a case of pulmonary mucormycosis survived after the therapy with amphotericin B and surgery. ...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,评审
doi：
更新日期：1996-01-01 00:00:00
abstract：:Bronchial benign tumors comprise fewer than 4% of pulmonary neoplasms. Endobronchial lipoma is an extremely rare benign neoplasm accounting for only 0.1% to 0.5% of all lung tumors. Clinical symptoms of lipoma depend on the location of the tumor, the severity of bronchial obstruction, and the functional and anatomical...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/s1579-2129(06)60418-7
更新日期：2005-03-01 00:00:00
abstract：OBJECTIVE:To determine if isoniazid- and/or rifampicin-free antituberculosis treatment regimens are safe and effective and to identify any factors that might require changes in the regimens. PATIENTS AND METHODS:We carried out a retrospective study of patients treated with isoniazid- and/or rifampicin-free regimens be...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：
更新日期：2008-09-01 00:00:00
abstract：OBJECTIVE:To compare the results of applying both the 1993 and 2002 guidelines of the Spanish Society of Pulmonology and Thoracic Surgery (SEPAR) to identify respiratory events during nighttime polysomnography tests. PATIENTS AND METHODS:One hundred twenty consecutive patients with medium to high suspicion of sleep ap...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/s1579-2129(06)60331-5
更新日期：2005-12-01 00:00:00
abstract：:Our objective was to study agreement between the compression ultrasound images taken in our respiratory medicine department and the duplex ultrasound images obtained by radiologists at our hospital for patients admitted to our ward with suspected diagnoses of venous thromboembolism.Seventy-eight consecutive patients a...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/s0300-2896(02)75185-5
更新日期：2002-04-01 00:00:00
abstract：BACKGROUND:There is comorbidity between respiratory disease and anxiety. In order to measure the anxiety of hospitalized patients it is necessary to use reliable and valid, and preferably short questionnaires. OBJECTIVE:To analyze the reliability and validity of a shortened version of the state subscale of the “State-...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,多中心研究
doi：10.1016/j.arbres.2010.11.006
更新日期：2011-04-01 00:00:00
abstract：:The use of novel tobacco products, particularly the electronic cigarette (EC) and partial tobacco combustion devices (HnB systems: Heat not Burn), has increased exponentially, particularly among adolescents and young people. The health authorities and scientific societies have shown concern about issues surrounding sa...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,评审
doi：10.1016/j.arbres.2019.04.023
更新日期：2019-11-01 00:00:00
abstract：:In non-small cell lung cancer, the EGFR gene mutations identify a patient sub-population with different clinical characteristics and treatment responses to those that do not have these mutations. There are mutations that derive in increased sensitive to EGFR targeted therapy, as well as mutations that result in resist...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/j.arbres.2010.06.013
更新日期：2011-02-01 00:00:00
abstract：:Omalizumab is a monoclonal antibody that interrupts allergic reaction--irrespective of the nature of the allergen--by blocking free immunoglobulin E (IgE). The IgE is thus prevented from attaching to cell receptors and setting in motion an allergic cascade of inflammatory mediators. Other interesting biological effect...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,评审
doi：10.1016/s1579-2129(06)60453-9
更新日期：2006-05-01 00:00:00
abstract：OBJECTIVE:Magnesium sulfate has been shown to have a bronchodilating effect in asthma, but this effect has not been clearly established in the context of chronic obstructive pulmonary disease (COPD). For this reason we investigated the possible bronchodilating effect of magnesium sulfate in COPD exacerbations. PATIENT...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,随机对照试验
doi：10.1016/s1579-2129(06)60551-x
更新日期：2006-08-01 00:00:00
abstract：:The diaphragm is the main muscle involved in ventilation and is supplied exclusively by the phrenic nerves. Congenital defects of the diaphragm muscle or phrenic nerve injury cause diaphragmatic paralysis-eventration. Prognosis and treatment depend on whether involvement is unilateral or bilateral and on the patient's...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,评审
doi：10.1016/S0300-2896(11)70066-7
更新日期：2011-01-01 00:00:00
abstract：:This case report describes two patients admitted to our hospital for elective surgery, one for biliary disease and the other for vascular disease. Shortly after surgery each presented a clinical picture attributable to membranous tracheal pars rupture caused by anesthetic intubation. Airway lesions were diagnosed and,...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,评审
doi：10.1016/s0300-2896(15)30646-3
更新日期：1997-03-01 00:00:00
abstract：OBJECTIVES:To analyze the prevalence and evolution of tuberculous infection among 6-year-olds in Albacete and its relation to socioeconomic status of the family. METHOD:A tuberculin test (2UT RT-23 Tween 80) was given to 6-year-old school children in and around Albacete in 1992 and 1999. We calculated the prevalence o...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/s0300-2896(02)75199-5
更新日期：2002-05-01 00:00:00
