Abstract：
:We assessed the clinicopathological features of solitary fibrous tumors of the pleura in a case series comprising 30 patients (20 women, 66.6%) with a mean age of 58.39 years. Forty-five percent of the cases were asymptomatic. In 70% of the cases the tumors arose in the visceral pleura. Twenty percent presented multiple tumors, a finding that was associated with intrapulmonary localization and malignant behavior (P<.0001) Histology revealed low cell density in 15% of the cases, moderate density in 50%, and high density in 35%; further findings showed atypia in 45% of the cases, necrosis in 25%, and hemorrhage in 15%. More than 4 mitoses per 10 high-power fields were noted in 30% of the cases. Immunohistochemistry results were positive for vimentin in all cases; cells were CD34+ in 85% of the cases, BCL2+ in 65%, and CD99+ in 40%. Findings for keratin and protein S100 were negative in all cases. Malignant biological behavior (local recurrence and metastasis) was observed in 4 cases, 2 of which were CD34-. Solitary fibrous tumors of the pleura are uncommon neoplasms with unpredictable biological behavior; follow-up should therefore be based on early detection of recurrence or metastasis.
journal_name
Arch Bronconeumoljournal_title
Archivos de bronconeumologiaauthors
Sánchez-Mora N,Cebollero-Presmanes M,Monroy V,Carretero-Albiñana L,Herranz-Aladro M,Alvarez-Fernández Edoi
10.1016/s1579-2129(06)60124-9keywords:
subject
Has Abstractpub_date
2006-02-01 00:00:00pages
96-9issue
2eissn
0300-2896issn
1579-2129pii
13084401journal_volume
42pub_type
杂志文章,评审abstract：:During the natural history of patients with chronic obstructive pulmonary disease (COPD), an increase in symptom severity can occur, called exacerbated COPD (ECOPD), sometimes requiring hospital admission. Although there is ongoing debate on the definition of ECOPD--leading to a lack of homogeneity in the numerous stu...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,评审
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abstract：:Chest ultrasound, a diagnostic technique used mainly by radiologists, is useful for managing pleural effusion. Sonography and computed tomography (CT) are complementary, although the former is more accessible to clinicians because it is safe and easy to use and because results are available quickly. We evaluated the u...
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journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,多中心研究
doi：
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journal_title：Archivos de bronconeumologia
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更新日期：2001-04-01 00:00:00
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journal_title：Archivos de bronconeumologia
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pub_type： 杂志文章,评审
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更新日期：2011-10-01 00:00:00
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更新日期：2007-01-01 00:00:00
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