Abstract：
INTRODUCTION:Primary ciliary dyskinesia (PCD) is a congenital disease characterized by impaired ciliary function, which involves a wide range of symptoms that are mainly respiratory. Recent articles that base diagnosis on ciliary ultrastructural studies have estimated its prevalence to be 1/10,000 newborns, which is higher than previously thought. Our objective is to define criteria for clinical suspicion of DCP that would indicate ultrastructural studies, while optimizing these and providing early diagnoses. METHODS:Ours is a descriptive, retrospective review of patients diagnosed with DCP in the Pediatric Pulmonology Unit at our hospital, from 1994 to 2010. The inclusion of cases was based on clinical suspicion criteria. Diagnosis was confirmed by characteristic ultrastructural changes observed in the electron microscopic study of the cilia. RESULTS:Sixty-three samples were analyzed, and 34 cases of DCP and one case of acilia were confirmed. Mean age at diagnosis was 3.6 (range: 1 month to 19 years of age). The most frequent initial symptom was prolonged neonatal tachypnea in the newborns (20%) and lower respiratory tract episodes in the school-aged patients: recurrent pneumonia (46%), difficult-to-control asthma (26%), bronchiectasis (8.6%) and massive atelectasis (2.9%). Associated symptoms were present in 46% of the cases. CONCLUSION:Our publication proposes the implementation of several clinical criteria depending on the age of presentation that would indicate the active search for alterations in the ciliary epithelium at reference centers.
journal_name
Arch Bronconeumoljournal_title
Archivos de bronconeumologiaauthors
Busquets RM,Caballero-Rabasco MA,Velasco M,Lloreta J,García-Algar Ódoi
10.1016/j.arbres.2012.10.007subject
Has Abstractpub_date
2013-03-01 00:00:00pages
99-104issue
3eissn
0300-2896issn
1579-2129pii
S0300-2896(12)00308-0journal_volume
49pub_type
杂志文章abstract：INTRODUCTION:Studies on inflammation biomarkers in serum and in exhaled breath condensate (EBC) in obstructive sleep apnea (OSA) have shown conflicting results. The objective of this study is to assess EBC and serum biomarkers in OSA patients at baseline and after continuous positive airway pressure (CPAP) or upper air...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
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更新日期：2014-10-01 00:00:00
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journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
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abstract：:Massive hemoptysis is a life-threatening emergency that rarely occurs in association with heart failure and is even less frequent when the underlying cause is dilated myocardiopathy. We report the case of a 69-year-old man with undiagnosed heart disease who presented with severe hemoptysis. Images showed evident cardi...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/s0300-2896(01)75092-2
更新日期：2001-07-01 00:00:00
abstract：:In both thromboembolic disease and pulmonary hypertension, 2010 has been a prodigious year for interesting publications. Some data have helped to elucidate the factors associated with a greater risk of thromboembolic disease, such as long journeys and certain polymorphisms. New recommendations on diagnosis have been m...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/S0300-2896(11)70003-5
更新日期：2011-01-01 00:00:00
abstract：OBJECTIVE:To analyze the results of resection of lung metastases from colorectal adenocarcinoma in selected patients, evaluating type of resection, morbidity and mortality associated with the procedure, and overall actuarial survival rates after surgery. PATIENTS AND METHODS:Between 1988 and 1996, 811 patients were tr...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：
更新日期：1999-04-01 00:00:00
abstract：:Bronchiectasis is the end result of several different diseases that share principles of management. The clinical course usually involves chronic bronchial infection and inflammation, which are associated with progression. The cause of bronchiectasis should always be investigated, particularly when it can be treated. W...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,实务指引
doi：10.1157/13128330
更新日期：2008-11-01 00:00:00
abstract：OBJECTIVE:To analyze the factors that determine the risk of morbidity and mortality associated with lung resection in patients with bronchogenic carcinoma. PATIENTS AND METHODS:Prospective multicenter study conducted between October 1, 1993 and September 30, 1997 in the 19 hospitals that make up the Bronchogenic Carci...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
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更新日期：2007-03-01 00:00:00
abstract：BACKGROUND:The non-adherence to tuberculosis treatment is associated with increased infection, antibiotic resistance, increased costs and death. Our objective was to identify factors associated with lack of completion of conventional treatment for tuberculosis in Peru. PATIENTS AND METHODS:An unmatched case-control st...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/j.arbres.2011.12.008
更新日期：2012-05-01 00:00:00
abstract：:One-third of the world-wide population currently presents latent tuberculosis infection (LTI). In Spain, TB is situated as the third disease of mandatory notification. The standard technique for the diagnosis of ITL is the tuberculin test (PPD), although its most important drawback is its specificity since the protein...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,评审
doi：10.1016/j.arbres.2011.06.018
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journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/j.arbres.2010.04.011
更新日期：2010-08-01 00:00:00
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journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/s0300-2896(15)30613-x
更新日期：1997-05-01 00:00:00
abstract：:Chest ultrasonography is a useful tool for assessing disease activity in the peripheral lung parenchyma, pleura, chest wall, diaphragm, and mediastinum. Ultrasound imaging also provides highly useful guidance in invasive diagnostic and therapeutic procedures. The main advantages of this imaging technology are the abse...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,评审
doi：10.1016/j.arbres.2008.12.004
更新日期：2010-01-01 00:00:00
abstract：INTRODUCTION AND AIMS:Chronic inflammation plays a major role in lung deterioration in cystic fibrosis (CF) patients and anti-inflammatory strategies have beneficial effects. To study the changes seen after a one-year course of low-dose dietary supplements with a mixture of fatty acids in adult patients with CF in chro...
journal_title：Archivos de bronconeumologia
pub_type： 临床试验,杂志文章
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更新日期：2010-02-01 00:00:00
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journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
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更新日期：2017-03-01 00:00:00
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journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
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更新日期：2018-05-01 00:00:00
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pub_type： 杂志文章
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更新日期：2019-08-01 00:00:00
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journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：
更新日期：2008-07-01 00:00:00
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journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/s0300-2896(03)75314-9
更新日期：2003-01-01 00:00:00
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journal_title：Archivos de bronconeumologia
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abstract：INTRODUCTION:Few studies have examined the 24-hour symptom profile in patients with chronic obstructive pulmonary disease (COPD). The main objective of this study was to determine daily variations in the symptoms of patients with stable COPD in Spain, compared with other European countries. METHODS:Observational study...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,多中心研究
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更新日期：2016-06-01 00:00:00
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journal_title：Archivos de bronconeumologia
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更新日期：2010-01-01 00:00:00
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journal_title：Archivos de bronconeumologia
pub_type： 临床试验,杂志文章
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更新日期：1996-02-01 00:00:00
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pub_type： 杂志文章
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更新日期：2003-03-01 00:00:00
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更新日期：2008-06-01 00:00:00
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journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
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更新日期：2015-06-01 00:00:00
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journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,评审
doi：
更新日期：1996-01-01 00:00:00
