Abstract：
BACKGROUND:One-year survival in lung transplant is around 85%, but this figure has not increased in recent years, in spite of technical improvements. METHODS:Retrospective, multicenter cohort study. Data from 272 eligible adults with lung transplant were recorded at 7 intensive care units (ICU) in Spain in 2013. The objective was to identify variables that might help to guide future clinical interventions in order to reducethe risk of death in the postoperative period. RESULTS:One patient (0.3%) died in the operating room and 27 (10%) within 90 days. Twenty (7.4%) died within 28 days, after a median of 14 ICU days. Grade 3 pulmonary graft dysfunction was documented in 108 patients, of whom 21 died, compared with 6 out of 163 without pulmonary graft dysfunction (P<.001). At ICU admission, non-survivors had significantly lower (P=.03) median PaO2/FiO2 (200mmHg vs 280mmHg), and the difference increased after 24hours (178 vs 297mmHg, P<.001). Thirteen required extracorporeal membrane oxygenation, and 7(53.8%) died. A logistic regression model identified pulmonary graft dysfunction (OR: 6.77), donor age>60yr (OR: 2.91) and SOFA>8 (OR: 2.53) as independent predictors of 90-day mortality. At ICU admission, higher median procalcitonin (1.6 vs 0.6) and lower median PaO2/FiO2 (200 vs 280mmHg) were significantly associated with mortality. CONCLUSION:Graft dysfunction remains a significant problem in lung transplant. Early ICU interventions in patients with severe hypoxemia or high procalcitonin are crucial in order to lower mortality.
journal_name
Arch Bronconeumoljournal_title
Archivos de bronconeumologiaauthors
Rello J,Bello I,de Vicente R,Hermira Anchuelo A,Ballesteros MÁ,Iranzo R,Rellán L,Riera J,Robles JC,EMPRET Study investigators.doi
10.1016/j.arbres.2016.12.019subject
Has Abstractpub_date
2017-08-01 00:00:00pages
421-426issue
8eissn
0300-2896issn
1579-2129pii
S0300-2896(17)30030-3journal_volume
53pub_type
杂志文章,多中心研究abstract：:The population pyramid is changing due to the increasing longevity of the population, making it a priority to have better knowledge of those diseases that have an increasingly major impact in advanced age. Sleep apnea-hypopnea syndrome (SAHS) affects 15-20% of individuals over 65 years. However, despite this high prev...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,评审
doi：10.1016/j.arbres.2010.05.003
更新日期：2010-09-01 00:00:00
abstract：BACKGROUND:Patients with activating somatic mutations in the Epidermal Growth Factor Receptor (EGFR) have better clinical outcomes when treated with Tyrosine Kinase Inhibitors (TKI) over chemotherapy. However, the impact of the use of TKIs on overall survival outside clinical trials is not well established. OBJECTIVE:...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/j.arbres.2017.07.012
更新日期：2018-01-01 00:00:00
abstract：:The use of novel tobacco products, particularly the electronic cigarette (EC) and partial tobacco combustion devices (HnB systems: Heat not Burn), has increased exponentially, particularly among adolescents and young people. The health authorities and scientific societies have shown concern about issues surrounding sa...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,评审
doi：10.1016/j.arbres.2019.04.023
更新日期：2019-11-01 00:00:00
abstract：OBJECTIVE:To study the microbiology of cystic fibrosis in our hospital for the period from 1985 to 1992. MATERIAL AND METHODS:The number of samples analyzed totalled 1,034, most of which were sputum and nasopharyngeal aspirates belonging to 113 patients (49 women and 64 men). The average age was 10 years (range: 15 da...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：
更新日期：1995-12-01 00:00:00
abstract：BACKGROUND:Two previous national epidemiological studies, IBERPOC in 1997 and EPISCAN in 2007, determined the COPD burden in Spain. Changes in demographics and exposure to risk factors demand the periodic update of COPD prevalence and its determinants. METHODS:EPISCAN II aimed to estimate the prevalence of COPD in the...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/j.arbres.2020.07.024
更新日期：2021-01-01 00:00:00
abstract：:Assessment of alpha 1-antitrypsin replacement therapy (AAT) for emphysema. Patient characteristics were analyzed along with the possible side effects of the treatment and its efficacy in maintaining appropriate AAT blood levels. Lung function changes were also studied. The treatment protocol began with 4 weekly intrav...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/s0300-2896(15)30997-2
更新日期：1994-12-01 00:00:00
abstract：:Changes in nutritional status, such as weight loss and malnutrition, are a very common complication in patients with chronic obstructive pulmonary disease (COPD). These changes primarily affect the patients' quality of life and functional capacity and they are also independent prognostic indicators of both morbidity a...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,评审
doi：
更新日期：2007-05-01 00:00:00
abstract：OBJECTIVE:Kartagener's syndrome (KS) is a clinical variant of primary ciliary dyskinesia involving situs inversus associated with chronic airway infections. The ciliary defect associated with this syndrome is the absence of dynein arms. The aim of this study was to evaluate mucociliary transport and ciliary ultrastruct...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/s1579-2129(06)60388-1
更新日期：2005-01-01 00:00:00
abstract：:Sixty patients diagnosed as having chronic respiratory diseases were surveyed in order to establish how many knew the name of their disease, the medications they were taking, the name of the medical specialty dedicated to treating their condition and the nature of spirometry. Only 23 patients (38%) knew the name of th...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/s0300-2896(15)31111-x
更新日期：1994-03-01 00:00:00
abstract：OBJECTIVE:The bronchial challenge test is commonly used to diagnose asthma but it is a tedious, time-consuming procedure. Although in recent years, several shortened methods have been proposed, it has been shown that they can give rise to exaggerated bronchoconstriction. The aims of the present study were a) to determi...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：
更新日期：2008-08-01 00:00:00
abstract：:One-third of the world-wide population currently presents latent tuberculosis infection (LTI). In Spain, TB is situated as the third disease of mandatory notification. The standard technique for the diagnosis of ITL is the tuberculin test (PPD), although its most important drawback is its specificity since the protein...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,评审
doi：10.1016/j.arbres.2011.06.018
更新日期：2011-10-01 00:00:00
abstract：OBJECTIVE:Although surgical pulmonary thromboendarterectomy is the treatment of choice for pulmonary hypertension due to chronic thrombotic and/or embolic disease, minimally invasive endovascular techniques such as angioplasty or placement of a metallic stent can provide acceptable results when surgery is not indicated...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/s1579-2129(08)60051-8
更新日期：2008-06-01 00:00:00
abstract：INTRODUCTION:Intermediate respiratory care units (IRCU) provide continuous monitoring and non-invasive mechanical ventilation (NIMV) in patients with severe respiratory failure who are usually admitted to intensive care units (ICU). The usefulness of IRCU in managing severe asthma exacerbations has never been evaluated...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/j.arbres.2012.11.009
更新日期：2013-04-01 00:00:00
abstract：:Cytological characteristics are reported in the case of a 20-years-old male with pulmonary inflammatory pseudotumor (PIP) diagnosed by fine-needle aspiration (FNA) and later confirmed histologically. The patient presented a large tumor on the lower lobe of the right lung with hemoptysis, hemothorax and secondary acute...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,评审
doi：
更新日期：1994-04-01 00:00:00
abstract：INTRODUCTION:Persistent air leak is frustrating for both patients and physicians, above all leaks with a high risk of surgery. Insertion of endobronchial valves could be an alternative to surgery. The aim of this study is to describe our experience in these valves and analyse their efficacy in a series of patients with...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/j.arbres.2014.04.007
更新日期：2015-01-01 00:00:00
abstract：OBJECTIVE:Although altered vascular permeability and edema of the bronchial mucosa are associated with asthma attack, their influence on its severity remains unknown. We address this issue by comparing relative indices for the concentration of albumin (RIAlb) and alpha2-macroglobulin (RIalpha2M) in induced sputum and p...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/s1579-2129(06)60232-2
更新日期：2005-06-01 00:00:00
abstract：:Traditional medical practice has been "reactive" (doctor takes part when disease appears). The theoretical (scale free networks and complex systems), technological (high efficiency "omic" technologies) and conceptual (biology systems) advances throughout the last decade, allow us to anticipate the transition to an "an...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,评审
doi：10.1016/j.arbres.2010.09.009
更新日期：2011-01-01 00:00:00
abstract：OBJECTIVES:To analyze the prevalence and evolution of tuberculous infection among 6-year-olds in Albacete and its relation to socioeconomic status of the family. METHOD:A tuberculin test (2UT RT-23 Tween 80) was given to 6-year-old school children in and around Albacete in 1992 and 1999. We calculated the prevalence o...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/s0300-2896(02)75199-5
更新日期：2002-05-01 00:00:00
abstract：:Asthma continues to be a global health problem, despite advances in diagnostic techniques and treatment. The inflammatory nature of asthma is currently indisputable, as is the involvement of the entire respiratory tree, both the proximal and most distal airways, which has been demonstrated in multiple studies. The dev...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,评审
doi：10.1016/S0300-2896(11)70016-3
更新日期：2011-04-01 00:00:00
abstract：:To assess the effect on tracheal graft preservation of perfusion of donor tissue with a Collins solution before extraction and immunosuppression of the recipient. An experimental study was performed in 36 albino rabbits with revascularized heterotopic cervical reconstruction of the trachea with omentum. The animals we...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/s0300-2896(15)30515-9
更新日期：1997-12-01 00:00:00
abstract：INTRODUCTION:The effectiveness of needle aspiration in the initial treatment of primary spontaneous pneumothorax has been widely studied. The objective of this research was to compare digital with manual aspiration in a randomized clinical trial. METHODS:We designed a blinded parallel-group randomized clinical trial w...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/j.arbres.2020.01.016
更新日期：2020-10-01 00:00:00
abstract：UNLABELLED:The diaphragm seems to undergo adaptive structural change in chronic obstructive pulmonary disease. The possibility of obtaining muscle specimens is limited, however, particularly when respiratory function is severely affected. OBJECTIVE:To assess the viability of a new technique for obtaining diaphragm mus...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/s0300-2896(15)30228-3
更新日期：2000-01-01 00:00:00
abstract：:Pancoast's syndrome is characterized by pain in the shoulders and upper extremities, Horner's syndrome, bone loss and hand muscle atrophy. Bronchogenic carcinoma is the most common cause, although other neoplasms or lung infection are occasionally responsible. An apical mass on the chest film can be seen in over 90% o...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/s0300-2896(15)30418-x
更新日期：1998-06-01 00:00:00
abstract：OBJECTIVE:This study assessed vena cava filter (VCF) retrieval rates and factors associated with retrieval failure in a single center cohort. METHODS:We conducted an observational retrospective cohort study. The primary endpoint was the percentage of patients whose VCF was retrieved. We performed logistic regression t...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/j.arbres.2018.02.008
更新日期：2018-03-19 00:00:00
abstract：INTRODUCTION:Pulse transit time (PTT) is the time that a pulse wave takes to travel between two different arterial points, and may be useful in estimating blood pressure. This noninvasive technique, which does not add any cost to the procedure, offers the advantage of avoiding 'arousals' during sleep measurement as occ...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/j.arbres.2013.12.001
更新日期：2014-07-01 00:00:00
abstract：:Specific bronchial challenge (SBC) testing is a key technique for diagnosing the origin of occupational asthma (OA). SBC is indicated in specific circumstances, including whenever several agents present in the work environment may be the cause of OA, when new or unusual occupational agents need to be identified, when ...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/s0300-2896(15)30546-9
更新日期：1997-10-01 00:00:00
abstract：OBJECTIVES:Although lung cancer is the most frequently diagnosed tumor world-wide, the real incidence of this diagnosis in Spain is unknown. To contribute to determining the incidence of lung cancer in this country, and in view of the lack of data from the community of Castilla-León, we carried out the present study. ...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,多中心研究
doi：
更新日期：2000-06-01 00:00:00
abstract：:Despite wide antiretroviral scale-up during the past two decades resulting in declining new infections and mortality globally, HIV-associated tuberculosis remains as a major public health concern. Tuberculosis is the leading HIV-associated opportunistic infection and the main cause of death globally and, particularly,...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,评审
doi：10.1016/j.arbres.2019.11.015
更新日期：2020-07-01 00:00:00
abstract：OBJECTIVE:To compare the effects of a simple home pulmonary rehabilitation program and an intensive hospital-based program in terms of the exercise tolerance and health-related quality of life (HRQL) of patients with severe chronic obstructive pulmonary disease (COPD). PATIENTS AND METHODS:Patients in this prospective...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,多中心研究,随机对照试验
doi：
更新日期：2008-10-01 00:00:00
abstract：:Chlamydia pneumoniae has often been implicated in respiratory tract infections concomitant with other pathogens. Although this agent has also been associated with other nonrespiratory diseases, to our knowledge it has never been described with autoimmune hemolytic anemia. We present a case of pneumonia in which C. pne...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,评审
doi：10.1016/s0300-2896(15)30772-9
更新日期：1996-05-01 00:00:00
