Abstract:
:Traditional medical practice has been "reactive" (doctor takes part when disease appears). The theoretical (scale free networks and complex systems), technological (high efficiency "omic" technologies) and conceptual (biology systems) advances throughout the last decade, allow us to anticipate the transition to an "anticipatory" medicine, based on health (not on disease). This review establishes the conceptual bases and discusses the principal aspects of this new medicine, known as "P4 Medicine" standing for personalized, predictive, preventive and participatory.
journal_name
Arch Bronconeumoljournal_title
Archivos de bronconeumologiaauthors
Sobradillo P,Pozo F,Agustí Adoi
10.1016/j.arbres.2010.09.009subject
Has Abstractpub_date
2011-01-01 00:00:00pages
35-40issue
1eissn
0300-2896issn
1579-2129pii
S0300-2896(10)00288-7journal_volume
47pub_type
杂志文章,评审abstract:BACKGROUND:Tumor necrosis factor alpha (TNF-alpha) has been implicated in loss of muscle mass in chronic obstructive pulmonary disease and other consumptive processes. TNF-alpha production would be related to inflammation arising from pulmonary disease itself or, alternatively, from smoking, and would be carried to the...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(02)75224-1
更新日期:2002-07-01 00:00:00
abstract::Very few cases of lung transplantation have been described for patients with Kartagener's syndrome. We report the first case to be published in Spain. A 15-year-old girl with complete Kartagener's syndrome underwent sequential transplantation of both lungs. Due to the unusual distribution of the organs in this syndrom...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,评审
doi:
更新日期:2000-02-01 00:00:00
abstract:OBJECTIVE:To assess the effect of adequate outpatient care as defined by guidelines of the Global Initiative for Asthma (GINA) on the long-term outcome of near-fatal asthma. PATIENTS AND METHODS:Fifty-three patients who had experienced a near-fatal attack of asthma were treated according to the GINA guidelines and fol...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:
更新日期:2008-04-01 00:00:00
abstract:INTRODUCTION:Studies on inflammation biomarkers in serum and in exhaled breath condensate (EBC) in obstructive sleep apnea (OSA) have shown conflicting results. The objective of this study is to assess EBC and serum biomarkers in OSA patients at baseline and after continuous positive airway pressure (CPAP) or upper air...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2014.02.016
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVE:To analyze the reliability and validity of the short form of the generic quality of life scale (SF-36) when used with our asthmatic patients. METHODS:Two hundred nineteen adults with asthma of any etiology and without limits on sex, type or severity of asthma who were being treated at 10 health clinics (Madr...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(02)75139-9
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:One-year survival in lung transplant is around 85%, but this figure has not increased in recent years, in spite of technical improvements. METHODS:Retrospective, multicenter cohort study. Data from 272 eligible adults with lung transplant were recorded at 7 intensive care units (ICU) in Spain in 2013. The o...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,多中心研究
doi:10.1016/j.arbres.2016.12.019
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:Proper reference values for lung function testing are essential for achieving adequate interpretations. The LMS procedure (lambda, mu, sigma) permits continuous analyses of entire populations avoiding gaps in the transition between childhood and adulthood. It also allows more precise calculations of average ...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2019.12.033
更新日期:2020-02-29 00:00:00
abstract::We report a patient with pneumonia and empyema secondary to an abdominal abscess due to Klebsiella pneumoniae from stones released into the abdominal cavity during laparoscopic cholecystectomy. ...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(01)75065-x
更新日期:2001-05-01 00:00:00
abstract::Peribronchiolar metaplasia is a histologic lesion characterized by fibrosis and bronchiolar epithelial proliferation, affecting peribronchiolar alveolar septa and terminal bronchioles. It has been considered a nonspecific tissue reaction secondary to the action of external factors, such as tobacco smoke and microbes, ...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2007.11.001
更新日期:2009-01-01 00:00:00
abstract::The use of novel tobacco products, particularly the electronic cigarette (EC) and partial tobacco combustion devices (HnB systems: Heat not Burn), has increased exponentially, particularly among adolescents and young people. The health authorities and scientific societies have shown concern about issues surrounding sa...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,评审
doi:10.1016/j.arbres.2019.04.023
更新日期:2019-11-01 00:00:00
abstract::Bronchial benign tumors comprise fewer than 4% of pulmonary neoplasms. Endobronchial lipoma is an extremely rare benign neoplasm accounting for only 0.1% to 0.5% of all lung tumors. Clinical symptoms of lipoma depend on the location of the tumor, the severity of bronchial obstruction, and the functional and anatomical...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s1579-2129(06)60418-7
更新日期:2005-03-01 00:00:00
abstract:INTRODUCTION:The purpose of the present study is to analyse the prevalence and distribution of asbestos lung residue in the Barcelona urban population. MATERIAL AND METHODS:Lung autopsy samples were obtained from 35 individuals who had lived in Barcelona. The close family were interviewed in order to rule out asbestos...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2009.12.008
更新日期:2010-04-01 00:00:00
abstract::The population pyramid is changing due to the increasing longevity of the population, making it a priority to have better knowledge of those diseases that have an increasingly major impact in advanced age. Sleep apnea-hypopnea syndrome (SAHS) affects 15-20% of individuals over 65 years. However, despite this high prev...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,评审
doi:10.1016/j.arbres.2010.05.003
更新日期:2010-09-01 00:00:00
abstract::We reviewed 73 cases of bronchial tuberculosis (59 adults and 14 children) diagnosed between 1973 and 2000 using histologic and bacteriologic criteria. The most frequent symptom was cough. Radiographic studies showed an alveolar pattern in 35 cases and obstructive pneumonitis or atelectasis in 28 cases. Endoscopy resu...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:
更新日期:2008-05-01 00:00:00
abstract:INTRODUCTION:Few studies have examined the 24-hour symptom profile in patients with chronic obstructive pulmonary disease (COPD). The main objective of this study was to determine daily variations in the symptoms of patients with stable COPD in Spain, compared with other European countries. METHODS:Observational study...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,多中心研究
doi:10.1016/j.arbres.2015.11.010
更新日期:2016-06-01 00:00:00
abstract::This case report describes two patients admitted to our hospital for elective surgery, one for biliary disease and the other for vascular disease. Shortly after surgery each presented a clinical picture attributable to membranous tracheal pars rupture caused by anesthetic intubation. Airway lesions were diagnosed and,...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,评审
doi:10.1016/s0300-2896(15)30646-3
更新日期:1997-03-01 00:00:00
abstract::Chronic obstructive pulmonary disease (COPD) is a chronic disease causing increasing healthcare costs worldwide. Another respiratory disease causing high costs and morbidity is community-acquired pneumonia (CAP). Because of the constant growth in the population with both diseases (CAP and COPD), analyzing their clinic...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,评审
doi:10.1016/S0300-2896(10)70024-7
更新日期:2010-01-01 00:00:00
abstract:INTRODUCTION AND OBJECTIVES:To determine the causes of death in patients operated on for stage IB non-small cell lung cancer (NSCLC) and to assess the impact on survival of the number of lymph nodes removed. PATIENTS AND METHOD:We studied 300 patients operated on for stage IB NSCLC. Only palpable or visible lymph node...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2008.05.003
更新日期:2009-02-01 00:00:00
abstract:INTRODUCTION AND OBJECTIVE:Non-tuberculous mycobacteria (NTM) isolates are becoming more common. The main objective of our study was to establish the number and diversity of NTM species in our region and their distribution according to the source sample, age and gender of the patients, and to analyse clinically signifi...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2017.02.014
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND:Two previous national epidemiological studies, IBERPOC in 1997 and EPISCAN in 2007, determined the COPD burden in Spain. Changes in demographics and exposure to risk factors demand the periodic update of COPD prevalence and its determinants. METHODS:EPISCAN II aimed to estimate the prevalence of COPD in the...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2020.07.024
更新日期:2021-01-01 00:00:00
abstract:OBJECTIVE:Certain sporting activities may trigger asthma exacerbations of varying intensity in children. Such exacerbations may lead to limitations in and rejection of such activities. During school hours, teachers are in a good position to observe these phenomena. The aim of the present study was to evaluate the shutt...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s1579-2129(06)60588-0
更新日期:2006-11-01 00:00:00
abstract::Inpatient management of malignant pleural effusion includes the placement of a conventional thoracostomy tube for drainage and talc slurry pleurodesis and/or a surgical approach consisting of video-assisted thoracoscopic talc insufflation. Both techniques require prolonged hospital stays of up to 1 week. Unfortunately...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s1579-2129(07)60008-1
更新日期:2006-12-01 00:00:00
abstract:UNLABELLED:The diaphragm seems to undergo adaptive structural change in chronic obstructive pulmonary disease. The possibility of obtaining muscle specimens is limited, however, particularly when respiratory function is severely affected. OBJECTIVE:To assess the viability of a new technique for obtaining diaphragm mus...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(15)30228-3
更新日期:2000-01-01 00:00:00
abstract::To check the technical specifications of 5 O2 concentrators pertaining to 5 different brands: Mark 4, Zefir, Puritan-Bennet, Drager and MHF prototype. The concentrators worked continuously for 37 days. External filters were cleaned after 400 hours and measurements were taken when theoretical flows were between 1 and 3...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:
更新日期:1995-10-01 00:00:00
abstract:INTRODUCTION:Pulse transit time (PTT) is the time that a pulse wave takes to travel between two different arterial points, and may be useful in estimating blood pressure. This noninvasive technique, which does not add any cost to the procedure, offers the advantage of avoiding 'arousals' during sleep measurement as occ...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2013.12.001
更新日期:2014-07-01 00:00:00
abstract:OBJECTIVE:Diffuse interstitial lung diseases (DILD) form a group of diseases which affect the alveolar interstitial space and share very similar clinical, radiological, and functional features, making lung biopsy essential for establishing diagnosis, prognosis, and treatment in many cases. We aimed to see whether there...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s1579-2129(06)60284-x
更新日期:2005-10-01 00:00:00
abstract::In non-small cell lung cancer, the EGFR gene mutations identify a patient sub-population with different clinical characteristics and treatment responses to those that do not have these mutations. There are mutations that derive in increased sensitive to EGFR targeted therapy, as well as mutations that result in resist...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2010.06.013
更新日期:2011-02-01 00:00:00
abstract::Since antileukotriene treatment for asthma was introduced, there has been debate about whether such therapy can lead to Churg-Strauss Syndrome (CSS) or whether CSS is simply inhibited by the use of steroids, as various authors have suggested. We report a case in which we suspected CSS in a patient with bronchopulmonar...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,评审
doi:10.1016/s0300-2896(01)75007-7
更新日期:2001-01-01 00:00:00
abstract::Assessment of alpha 1-antitrypsin replacement therapy (AAT) for emphysema. Patient characteristics were analyzed along with the possible side effects of the treatment and its efficacy in maintaining appropriate AAT blood levels. Lung function changes were also studied. The treatment protocol began with 4 weekly intrav...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(15)30997-2
更新日期:1994-12-01 00:00:00
abstract:OBJECTIVES:Although lung cancer is the most frequently diagnosed tumor world-wide, the real incidence of this diagnosis in Spain is unknown. To contribute to determining the incidence of lung cancer in this country, and in view of the lack of data from the community of Castilla-León, we carried out the present study. ...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,多中心研究
doi:
更新日期:2000-06-01 00:00:00