Abstract:
INTRODUCTION:Studies on inflammation biomarkers in serum and in exhaled breath condensate (EBC) in obstructive sleep apnea (OSA) have shown conflicting results. The objective of this study is to assess EBC and serum biomarkers in OSA patients at baseline and after continuous positive airway pressure (CPAP) or upper airway surgery (UAS). PATIENTS AND METHODS:Nine OSA patients referred for UAS were matched for anthropometric characteristics and apnea-hypopnea index with 20 patients receiving CPAP. pH, nitrite (NO2(-)), nitrate and interleukin 6 in EBC and NO2(-), nitrate, leukotriene B4 and interleukin 6 in serum were determined. EBC and serum samples were collected at baseline and 3 months after CPAP or UAS. RESULTS:Patients' mean body mass index was 30 (range 24.9-40) kg/m(2). EBC biomarker levels at baseline were within normal range and did not differ significantly after CPAP or UAS. No significant changes were observed in the serum concentration of the biomarkers determined after CPAP but the serum concentration of NO2(-) increased significantly at 3 months after UAS (P=.0078). CONCLUSION:In mildly obese OSA patients, EBC biomarkers of inflammation or oxidative stress were normal at baseline and remained unchanged 3 months after UAS or CPAP. Although UAS was not effective in terms of reducing OSA severity, it was associated with an increase in serum NO2(-).
journal_name
Arch Bronconeumoljournal_title
Archivos de bronconeumologiaauthors
Lloberes P,Sánchez-Vidaurre S,Ferré À,Cruz MJ,Lorente J,Sampol G,Morell F,Muñoz Xdoi
10.1016/j.arbres.2014.02.016subject
Has Abstractpub_date
2014-10-01 00:00:00pages
422-8issue
10eissn
0300-2896issn
1579-2129pii
S0300-2896(14)00108-2journal_volume
50pub_type
杂志文章abstract:INTRODUCTION:COPD and emphysema due to alpha-1 antitrypsin deficiency (AATD) are the first and fourth indications for lung transplantation worldwide, respectively. Despite this, there is little information regarding the health status of these patients at the time of transplantation. METHODS:Patients who received a lun...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2014.08.003
更新日期:2015-08-01 00:00:00
abstract:INTRODUCTION:The socioeconomic impact of obstructive sleep apnea-hypopnea syndrome (OSAHS) is considerable. The aim of this study was to evaluate the cost-effectiveness of treating OSAHS with continuous positive airway pressure (CPAP) and the impact of CPAP compliance. METHODS:This was a retrospective, case-crossover ...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2016.02.005
更新日期:2016-09-01 00:00:00
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journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2013.12.001
更新日期:2014-07-01 00:00:00
abstract::Cytological characteristics are reported in the case of a 20-years-old male with pulmonary inflammatory pseudotumor (PIP) diagnosed by fine-needle aspiration (FNA) and later confirmed histologically. The patient presented a large tumor on the lower lobe of the right lung with hemoptysis, hemothorax and secondary acute...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,评审
doi:
更新日期:1994-04-01 00:00:00
abstract:INTRODUCTION:The purpose of the present study is to analyse the prevalence and distribution of asbestos lung residue in the Barcelona urban population. MATERIAL AND METHODS:Lung autopsy samples were obtained from 35 individuals who had lived in Barcelona. The close family were interviewed in order to rule out asbestos...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2009.12.008
更新日期:2010-04-01 00:00:00
abstract::We aimed to determine which factors were related to the development of residual pleural thickening (RPT) after completion of prescribed treatment. Sixty-two patients with pleural tuberculosis (PTB) were assigned to 2 groups according to the presence or absence of RPT > 2 mm in the side and lower portion of a chest fil...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(15)30942-x
更新日期:1995-04-01 00:00:00
abstract::Conventional polysomnography (CPS) is a complex, costly procedure that is not widely available, meaning that it is difficult to apply it in patients suspected of having obstructive sleep apnea syndrome (OSAS). Various procedures have therefore been proposed for screening candidates for CPS. We studied the usefulness o...
journal_title:Archivos de bronconeumologia
pub_type: 临床试验,杂志文章
doi:
更新日期:1996-11-01 00:00:00
abstract:INTRODUCTION:NECPAL is a tool for identification of patients with advanced chronic disease in need of palliative care. The main objective of the study is to know the prevalence of patients with palliative needs in an acute respiratory ward in a Spanish tertiary hospital using NECPAL. A second objective of the study is ...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
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journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2011.12.008
更新日期:2012-05-01 00:00:00
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journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(15)31048-6
更新日期:1994-08-01 00:00:00
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journal_title:Archivos de bronconeumologia
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journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
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journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,meta分析,评审
doi:10.1016/s1579-2129(07)60016-0
更新日期:2007-01-01 00:00:00
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journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2015.01.014
更新日期:2015-10-01 00:00:00
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journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(15)30798-5
更新日期:1996-03-01 00:00:00
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journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
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更新日期:2020-08-01 00:00:00
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journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2017.11.015
更新日期:2018-05-01 00:00:00
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journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2010.07.013
更新日期:2011-01-01 00:00:00
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journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s1579-2129(06)60284-x
更新日期:2005-10-01 00:00:00
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journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:
更新日期:1999-04-01 00:00:00
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journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,评审
doi:10.1016/j.arbres.2014.06.017
更新日期:2015-03-01 00:00:00
abstract::In view of the presentations in the First National Forum of Trainee Pneumologists, the present article focuses on infectious pleural effusions and on the study of possible markers of malignant disease in asbestos-exposed individuals. The yield of the distinct techniques for the diagnosis of tuberculous pleural effusio...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/S0300-2896(09)72854-6
更新日期:2009-01-01 00:00:00
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journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s1579-2129(07)60127-x
更新日期:2007-10-01 00:00:00
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journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:
更新日期:2000-11-01 00:00:00
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journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2020.04.015
更新日期:2020-05-31 00:00:00
abstract:INTRODUCTION AND AIMS:Chronic inflammation plays a major role in lung deterioration in cystic fibrosis (CF) patients and anti-inflammatory strategies have beneficial effects. To study the changes seen after a one-year course of low-dose dietary supplements with a mixture of fatty acids in adult patients with CF in chro...
journal_title:Archivos de bronconeumologia
pub_type: 临床试验,杂志文章
doi:10.1016/j.arbres.2009.11.001
更新日期:2010-02-01 00:00:00
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journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2020.01.016
更新日期:2020-10-01 00:00:00
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journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,多中心研究
doi:10.1016/s0300-2896(03)75414-3
更新日期:2003-09-01 00:00:00
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journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s1579-2129(06)60232-2
更新日期:2005-06-01 00:00:00
abstract::We report our 3-years experience with video-thoracoscopy for pneumothorax. Forty-six endoscopies (34 men, 12 women; mean age 27 +/- 9 years) were performed. Patients were under general anesthesia and intubation was selective. The conventional approach was used, with 3 incisions through which the camera and endoscopic ...
journal_title:Archivos de bronconeumologia
pub_type: 临床试验,杂志文章
doi:10.1016/s0300-2896(15)30814-0
更新日期:1996-02-01 00:00:00