Abstract:
OBJECTIVE:To describe our experience in managing patients with Duchenne muscular dystrophy. PATIENTS AND METHODS:We analyzed the following variables in a group of 27 patients with Duchenne muscular dystrophy: arterial blood gases, lung function before and after mechanical ventilation, oxygen saturation (measured by pulse oximetry), nocturnal PaCO2 (measured transcutaneously by capnography), heart function, and dysphagia. RESULTS:The mean (SD) age was 26 (6) years and the mean age at which mechanical ventilation had initiated in the patients was 21 (5) years. Sixty-two percent had undergone tracheostomy and invasive mechanical ventilation. Arterial blood gas levels returned to normal once mechanical ventilation was administered and remained so for the entire treatment period (mean duration of follow-up, 56 [49] months). Thirteen patients had cardiac symptoms and they all presented abnormal electrocardiograms and echocardiograms indicating dilated cardiomyopathy, left ventricular dysfunction, and posterior hypokinesis. Only 9 patients were receiving enteral nutrition (7 through a gastrostomy tube and 2 through a nasogastric tube). The videofluoroscopic swallowing study confirmed that dysphagia was related to neuromuscular disease rather than the presence or not of a tracheostomy. Five patients (18%), 4 of whom were receiving invasive mechanical ventilation, died during the follow-up period. Three patients had serious heart disease. CONCLUSIONS:Mechanical ventilation confers clinical benefits and prolongs life expectancy in patients with Duchenne muscular dystrophy. Heart disease and feeding difficulties are determining factors in the prognosis of these patients.
journal_name
Arch Bronconeumoljournal_title
Archivos de bronconeumologiaauthors
Güell MR,Avendano M,Fraser J,Goldstein Rdoi
10.1016/s1579-2129(07)60127-xsubject
Has Abstractpub_date
2007-10-01 00:00:00pages
557-61issue
10eissn
0300-2896issn
1579-2129pii
13110881journal_volume
43pub_type
杂志文章abstract::Infection of the larynx by Candida is rare and usually accompanies lung or disseminated candidiasis. The incidence of isolated laryngeal candidiasis (ILC) is low, although it may be underestimated. We describe 2 patients with ILC confirmed during autopsy: a 45-years-old male with pulmonary fibrosis and a 4-years-old g...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(15)30789-4
更新日期:1996-04-01 00:00:00
abstract:OBJECTIVE:To analyse the results obtained in the diagnosis and staging of lung cancer (LC) by a Lung Cancer Rapid Diagnosis Unit (LC-RDU) in which real-time endobronchial ultrasound-guided transbronchial needle aspiration (RT-EBUS guided-TBNA) is performed as part of the clinical evaluation of the patient prior to trea...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2010.07.005
更新日期:2010-12-01 00:00:00
abstract::In non-small cell lung cancer, the EGFR gene mutations identify a patient sub-population with different clinical characteristics and treatment responses to those that do not have these mutations. There are mutations that derive in increased sensitive to EGFR targeted therapy, as well as mutations that result in resist...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2010.06.013
更新日期:2011-02-01 00:00:00
abstract:INTRODUCTION:In recent years, there has been debate regarding the diagnostic accuracy of computed tomography (CT) in the identification of lung metastases and the need for lung palpation to determine the number of metastatic nodules. The aim of this study was to determine in which patients the CT scan was more effectiv...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2013.05.006
更新日期:2013-12-01 00:00:00
abstract::Pulmonary neoplasms can deposit malignant cells in the pleural cavity by a variety of mechanisms, depending not only on histological type but also on clinical stage. We investigated the effect on survival rate of a finding of malignant cells in pleural lavage. We also investigated the effect of the presence of pleural...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:
更新日期:1996-08-01 00:00:00
abstract::The Clinical Notes published in 2009 serve as a resource to reflect on clinical aspects relevant to different clinical entities. Through this review an attempt is likewise made to bring the reader closer to the clinical reality of our environment. ...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,评审
doi:10.1016/j.arbres.2010.10.001
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Asthma's great impact on public health stems from its chronicity and to high prevalence among all age groups and both sexes. To estimate the appropriateness of treatment and management of asthma in Spain during the period of 1991 and 1992, we analyzed data from the European Community Respirato...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(15)30259-3
更新日期:1999-05-01 00:00:00
abstract:OBJECTIVE:PLATINO project is a population-based study designed to determine the prevalence of chronic obstructive pulmonary disease (COPD) in São Paulo, Brazil; Mexico City, Mexico; Montevideo, Uruguay; Santiago de Chile, Chile; and Caracas, Venezuela. The objective of this portion of PLATINO was to describe preventive...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,多中心研究
doi:10.1016/s1579-2129(08)60016-6
更新日期:2008-02-01 00:00:00
abstract:OBJECTIVE:To validate a cardiorespiratory polygraphy system (BITMED NGP 140) by comparing it to conventional polysomnography in the diagnosis of sleep apnea-hypopnea syndrome. PATIENTS AND METHODS:Polysomnography and cardio-respiratory polygraphy were performed simultaneously on 103 consecutive patients referred becau...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s1579-2129(06)60400-x
更新日期:2005-02-01 00:00:00
abstract:OBJECTIVES:Although an association between uric acid (UA) levels and obstructive sleep apnea (OSA) has been reported, the effect of continuous positive airway pressure (CPAP) on this measure is yet unclear. We aimed to investigate the effect of CPAP therapy on serum UA levels in patients with OSA. METHODS:We conducted...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.arbres.2018.09.012
更新日期:2019-04-01 00:00:00
abstract::We report a case of pleural effusion, pericardial thickening, and pulmonary involvement in a patient with dry cough, dyspnea, edema, and changes in the skin of the lower limbs. Treatment with cabergoline (Sogilen) had been started 4 months earlier. Pleural effusion, pericardial thickening, and impaired pulmonary funct...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s1579-2129(07)60118-9
更新日期:2007-09-01 00:00:00
abstract::Chest ultrasound, a diagnostic technique used mainly by radiologists, is useful for managing pleural effusion. Sonography and computed tomography (CT) are complementary, although the former is more accessible to clinicians because it is safe and easy to use and because results are available quickly. We evaluated the u...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(03)75376-9
更新日期:2003-06-01 00:00:00
abstract::Specific bronchial challenge (SBC) testing is a key technique for diagnosing the origin of occupational asthma (OA). SBC is indicated in specific circumstances, including whenever several agents present in the work environment may be the cause of OA, when new or unusual occupational agents need to be identified, when ...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(15)30546-9
更新日期:1997-10-01 00:00:00
abstract::The main causes of pleural fluid drainage failure are known to be the formation of fibrin septa, increased viscosity in pleural fluid and inappropriate placement of chest tubes. Reports also tell us that such problems can be solved by using ultrasound as a guide for tube placement and by infusing intrapleural fibrinol...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:
更新日期:1996-12-01 00:00:00
abstract::Omalizumab is a monoclonal antibody that interrupts allergic reaction--irrespective of the nature of the allergen--by blocking free immunoglobulin E (IgE). The IgE is thus prevented from attaching to cell receptors and setting in motion an allergic cascade of inflammatory mediators. Other interesting biological effect...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,评审
doi:10.1016/s1579-2129(06)60453-9
更新日期:2006-05-01 00:00:00
abstract:UNLABELLED:Hospitalizations for acute exacerbation of COPD (AECOPD) generate high consumption of health resources, frequent readmissions and high mortality. The MAG -1 study aims to identify critical points to improve the care process of severe AECOPD requiring hospitalization. METHODS:Observational study, with review...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,多中心研究
doi:10.1016/j.arbres.2014.06.023
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:Community-acquired pneumonia (CAP) is the leading cause of death from infectious disease among the elderly. This study was carried out to examine the clinical manifestations, etiology, prognostic factors and treatment of CAP in immunocompetent elderly patients requiring hospitalization. RESULTS:A total of 3...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(03)75400-3
更新日期:2003-08-01 00:00:00
abstract::Since antileukotriene treatment for asthma was introduced, there has been debate about whether such therapy can lead to Churg-Strauss Syndrome (CSS) or whether CSS is simply inhibited by the use of steroids, as various authors have suggested. We report a case in which we suspected CSS in a patient with bronchopulmonar...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,评审
doi:10.1016/s0300-2896(01)75007-7
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVE:To study the microbiology of cystic fibrosis in our hospital for the period from 1985 to 1992. MATERIAL AND METHODS:The number of samples analyzed totalled 1,034, most of which were sputum and nasopharyngeal aspirates belonging to 113 patients (49 women and 64 men). The average age was 10 years (range: 15 da...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:
更新日期:1995-12-01 00:00:00
abstract::We proposed to search for markers of hypercoagulable states in function of age, sex or factors that trigger venous thromboembolic disease (VTD) in a group of patients so diagnosed. The following patient data were analyzed: age, sex and triggering factors of VTD categorized as associative-transient, permanent or unknow...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:
更新日期:1999-07-01 00:00:00
abstract::Although bacteria are the main pathogens involved in community-acquired pneumonia, a significant number of community-acquired pneumonia are caused by viruses, either directly or as part of a co-infection. The clinical picture of these different pneumonias can be very similar, but viral infection is more common in the ...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,评审
doi:10.1016/j.arbres.2015.02.015
更新日期:2015-11-01 00:00:00
abstract::Spirometry is a basic lung function test useful both for measuring and for monitoring expiratory volume. For many years monitoring has been performed by means of a portable peak flow meter capable of measuring maximal expiratory flow. We present a portable spirometer (Spirotel, Medical International Research, Rome, It...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s1579-2129(06)60190-0
更新日期:2004-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the prevalence of sleep disorders in patients awaiting kidney transplants compared to a control group. PATIENTS AND METHODS:We carried out an observational study of 23 patients on a kidney transplant waiting list in comparison with 20 healthy volunteers matched for age, sex, and body mass index (...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:
更新日期:2008-07-01 00:00:00
abstract:OBJECTIVES:Although lung cancer is the most frequently diagnosed tumor world-wide, the real incidence of this diagnosis in Spain is unknown. To contribute to determining the incidence of lung cancer in this country, and in view of the lack of data from the community of Castilla-León, we carried out the present study. ...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,多中心研究
doi:
更新日期:2000-06-01 00:00:00
abstract:INTRODUCTION:The purpose of the present study is to analyse the prevalence and distribution of asbestos lung residue in the Barcelona urban population. MATERIAL AND METHODS:Lung autopsy samples were obtained from 35 individuals who had lived in Barcelona. The close family were interviewed in order to rule out asbestos...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2009.12.008
更新日期:2010-04-01 00:00:00
abstract::We aimed to determine which factors were related to the development of residual pleural thickening (RPT) after completion of prescribed treatment. Sixty-two patients with pleural tuberculosis (PTB) were assigned to 2 groups according to the presence or absence of RPT > 2 mm in the side and lower portion of a chest fil...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(15)30942-x
更新日期:1995-04-01 00:00:00
abstract::The population pyramid is changing due to the increasing longevity of the population, making it a priority to have better knowledge of those diseases that have an increasingly major impact in advanced age. Sleep apnea-hypopnea syndrome (SAHS) affects 15-20% of individuals over 65 years. However, despite this high prev...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,评审
doi:10.1016/j.arbres.2010.05.003
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND:One-year survival in lung transplant is around 85%, but this figure has not increased in recent years, in spite of technical improvements. METHODS:Retrospective, multicenter cohort study. Data from 272 eligible adults with lung transplant were recorded at 7 intensive care units (ICU) in Spain in 2013. The o...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,多中心研究
doi:10.1016/j.arbres.2016.12.019
更新日期:2017-08-01 00:00:00
abstract::Pulmonary artery hypertension (PAH) is a category of pulmonary hypertension consisting of mean pulmonary artery pressure greater than 25 mmHg at rest, with normal pulmonary capillary occlusion pressure (less than 15 mmHg) and pulmonary vascular resistance greater than 3 Wood units. The diagnosis of PAH is made through...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,评审
doi:10.1016/S0300-2896(11)70054-0
更新日期:2011-01-01 00:00:00
abstract::We report the case of a 61-year-old man with amyotrophic lateral sclerosis presenting with respiratory failure requiring long-term mechanical ventilation. Diagnostic difficulties are discussed along with the circumstances that give rise to suspicion of neuromuscular disease in a context of respiratory failure of unkno...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,评审
doi:10.1016/s0300-2896(15)30324-0
更新日期:1999-01-01 00:00:00