Abstract:
:Omalizumab is a monoclonal antibody that interrupts allergic reaction--irrespective of the nature of the allergen--by blocking free immunoglobulin E (IgE). The IgE is thus prevented from attaching to cell receptors and setting in motion an allergic cascade of inflammatory mediators. Other interesting biological effects of omalizumab are that it downregulates IgE receptor expression on cell membranes and reduces bronchial eosinophilic infiltration. Clinical trials have demonstrated omalizumab's efficacy and safety in treating most allergic disorders. However, given its high cost, omalizumab is generally reserved for more severe cases of asthma and for asthma that responds poorly to conventional treatments.
journal_name
Arch Bronconeumoljournal_title
Archivos de bronconeumologiaauthors
Cabrera-Navarro Pdoi
10.1016/s1579-2129(06)60453-9subject
Has Abstractpub_date
2006-05-01 00:00:00pages
241-5issue
5eissn
0300-2896issn
1579-2129pii
13088029journal_volume
42pub_type
杂志文章,评审abstract:INTRODUCTION:Asthma is an inflammatory disorder of the airways and the symptoms of asthma could be exacerbated by Mycoplasma pneumoniae infection. Interleukin-2 and interleukin-4 have been implicated in immune and inflammatory reactions. We examined the associations of IL2 and IL4 polymorphisms and expression with the ...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2014.11.004
更新日期:2015-11-01 00:00:00
abstract:INTRODUCTION:The objective of the present study was to validate the Spanish version of the SAQLI, which is a health-related quality of life (HRQL) questionnaire specific for sleep apnea-hypopnea syndrome (SAHS), and to assess its sensitivity to change. MATERIAL AND METHODS:A multicenter study performed in a group of p...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.arbres.2012.05.004
更新日期:2012-12-01 00:00:00
abstract:OBJECTIVE:Certain sporting activities may trigger asthma exacerbations of varying intensity in children. Such exacerbations may lead to limitations in and rejection of such activities. During school hours, teachers are in a good position to observe these phenomena. The aim of the present study was to evaluate the shutt...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s1579-2129(06)60588-0
更新日期:2006-11-01 00:00:00
abstract::Postoperative chylothorax after lung resection is a major problem leading to morbidity and mortality and requiring reoperation in a large number of cases. The most advisable and least aggressive option is conservative management in progressive stages: a diet rich in medium-chain fatty acids and/or total parenteral nut...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s1579-2129(06)60357-1
更新日期:2004-10-01 00:00:00
abstract::We reviewed 73 cases of bronchial tuberculosis (59 adults and 14 children) diagnosed between 1973 and 2000 using histologic and bacteriologic criteria. The most frequent symptom was cough. Radiographic studies showed an alveolar pattern in 35 cases and obstructive pneumonitis or atelectasis in 28 cases. Endoscopy resu...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:
更新日期:2008-05-01 00:00:00
abstract:INTRODUCTION:The diagnosis of latent tuberculous infection (LTI) by IGRA continues to generate debate. Experience in the simultaneous use of 2 IGRA tests is scant. The aim of this study was to compare the results of 2 versions of QuantiFERON-TB Gold (In-Tube/Plus) with those of T-SPOT.TB, and to analyse the effectivene...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2020.04.011
更新日期:2020-06-10 00:00:00
abstract:OBJECTIVE:To study the microbiology of cystic fibrosis in our hospital for the period from 1985 to 1992. MATERIAL AND METHODS:The number of samples analyzed totalled 1,034, most of which were sputum and nasopharyngeal aspirates belonging to 113 patients (49 women and 64 men). The average age was 10 years (range: 15 da...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:
更新日期:1995-12-01 00:00:00
abstract::Airway complications after lung transplant are relatively common although the rates vary according to the different studies. Pathogenesis is diverse but the principal mechanism is usually bronchus intermedius ischemia in the post-transplant period. One major complication is bronchial stenosis, with relatively frequent...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2013.12.005
更新日期:2015-02-01 00:00:00
abstract:BACKGROUND:Tumor necrosis factor alpha (TNF-alpha) has been implicated in loss of muscle mass in chronic obstructive pulmonary disease and other consumptive processes. TNF-alpha production would be related to inflammation arising from pulmonary disease itself or, alternatively, from smoking, and would be carried to the...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(02)75224-1
更新日期:2002-07-01 00:00:00
abstract::We report a patient with pneumonia and empyema secondary to an abdominal abscess due to Klebsiella pneumoniae from stones released into the abdominal cavity during laparoscopic cholecystectomy. ...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(01)75065-x
更新日期:2001-05-01 00:00:00
abstract::Atrophy and weakness of the respiratory and peripheral muscles is a common problem in the intensive care unit (ICU). It is difficult to diagnose, particularly in the early stages of critical disease. Consequently, many cases are detected only in advanced stages, for example, when difficulties in mechanical ventilation...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,评审
doi:10.1016/j.arbres.2018.09.002
更新日期:2019-05-01 00:00:00
abstract::We report the case of a 48-year-old woman with a diagnosis of pulmonary hypertension and hyperthyroidism (Graves' disease) in whom pulmonary artery pressures became normal after treatment of thyroid disease. The possible pathogenic mechanisms involved in this association include the presence of hyperdynamic heart fail...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(03)75314-9
更新日期:2003-01-01 00:00:00
abstract::Conventional polysomnography (CPS) is a complex, costly procedure that is not widely available, meaning that it is difficult to apply it in patients suspected of having obstructive sleep apnea syndrome (OSAS). Various procedures have therefore been proposed for screening candidates for CPS. We studied the usefulness o...
journal_title:Archivos de bronconeumologia
pub_type: 临床试验,杂志文章
doi:
更新日期:1996-11-01 00:00:00
abstract:OBJECTIVE:To analyze the results of resection of lung metastases from colorectal adenocarcinoma in selected patients, evaluating type of resection, morbidity and mortality associated with the procedure, and overall actuarial survival rates after surgery. PATIENTS AND METHODS:Between 1988 and 1996, 811 patients were tr...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:
更新日期:1999-04-01 00:00:00
abstract:INTRODUCTION:Primary palmar hyperhidrosis (PPH) mainly affects the sympathetic ganglia. This study aims to analyze the histopathological changes in the sympathetic ganglia of patients with PPH. MATERIAL AND METHOD:We studied 55 tissue samples from 35 patients with PPH who underwent T2-T3 gangliectomy for definitive tr...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(03)75337-x
更新日期:2003-03-01 00:00:00
abstract::The clinical usefulness of simple exercise tests in patients with chronic obstructive pulmonary disease (COPD) continues to give rise to debate. Questions remain about whether these tests assess maximum effort or only exercise tolerance (submaximal effort). To determine the levels of stress reached during the six-minu...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(01)75017-x
更新日期:2001-02-01 00:00:00
abstract:OBJECTIVE:To validate a cardiorespiratory polygraphy system (BITMED NGP 140) by comparing it to conventional polysomnography in the diagnosis of sleep apnea-hypopnea syndrome. PATIENTS AND METHODS:Polysomnography and cardio-respiratory polygraphy were performed simultaneously on 103 consecutive patients referred becau...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s1579-2129(06)60400-x
更新日期:2005-02-01 00:00:00
abstract:INTRODUCTION AND OBJECTIVES:To determine the causes of death in patients operated on for stage IB non-small cell lung cancer (NSCLC) and to assess the impact on survival of the number of lymph nodes removed. PATIENTS AND METHOD:We studied 300 patients operated on for stage IB NSCLC. Only palpable or visible lymph node...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2008.05.003
更新日期:2009-02-01 00:00:00
abstract:INTRODUCTION:Obesity is associated with 2 closely related respiratory diseases: obesity hypoventilation syndrome (OHS) and obstructive sleep apnea-hypopnea syndrome (OSAHS). It has been shown that noninvasive ventilation during sleep produces clinical and functional improvement in these patients. The long-term survival...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2014.02.015
更新日期:2015-02-01 00:00:00
abstract::Peribronchiolar metaplasia is a histologic lesion characterized by fibrosis and bronchiolar epithelial proliferation, affecting peribronchiolar alveolar septa and terminal bronchioles. It has been considered a nonspecific tissue reaction secondary to the action of external factors, such as tobacco smoke and microbes, ...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2007.11.001
更新日期:2009-01-01 00:00:00
abstract:INTRODUCTION AND OBJECTIVE:Non-tuberculous mycobacteria (NTM) isolates are becoming more common. The main objective of our study was to establish the number and diversity of NTM species in our region and their distribution according to the source sample, age and gender of the patients, and to analyse clinically signifi...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2017.02.014
更新日期:2017-10-01 00:00:00
abstract::Sixty-one patients with obstructive sleep apnea syndrome (OSAS), 26 of whom also had chronic obstructive pulmonary disease (COPD), received treatment by nasal continuous positive airways pressure (nCPAP). To evaluate the effects of this device on daytime lung function, we analyzed pulmonary function tests before treat...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(15)30982-0
更新日期:1995-01-01 00:00:00
abstract::Chlamydia pneumoniae has often been implicated in respiratory tract infections concomitant with other pathogens. Although this agent has also been associated with other nonrespiratory diseases, to our knowledge it has never been described with autoimmune hemolytic anemia. We present a case of pneumonia in which C. pne...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,评审
doi:10.1016/s0300-2896(15)30772-9
更新日期:1996-05-01 00:00:00
abstract:INTRODUCTION:Primary ciliary dyskinesia (PCD) is a congenital disease characterized by impaired ciliary function, which involves a wide range of symptoms that are mainly respiratory. Recent articles that base diagnosis on ciliary ultrastructural studies have estimated its prevalence to be 1/10,000 newborns, which is hi...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2012.10.007
更新日期:2013-03-01 00:00:00
abstract::In 2008, the Spanish Society of Pulmonology (SEPAR) published the first guidelines in the world on the diagnosis and treatment of bronchiectasis. Almost 10 years later, considerable scientific advances have been made in both the treatment and the evaluation and diagnosis of this disease, and the original guidelines ha...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,实务指引
doi:10.1016/j.arbres.2017.07.015
更新日期:2018-02-01 00:00:00
abstract::The aim of this prospective study was to evaluate video-assisted thoracoscopic surgery (VATS) in primary and secondary spontaneous pneumothoraces. Over a 37-month period, 107 videothoracoscopic interventions were performed to treat spontaneous pneumothorax in 105 patients, 78 men and 27 women, whose average age was 28...
journal_title:Archivos de bronconeumologia
pub_type: 临床试验,杂志文章
doi:10.1016/s0300-2896(03)75391-5
更新日期:2003-07-01 00:00:00
abstract::In the last few years, a large number of studies on mortality in patients with chronic obstructive pulmonary disease (COPD) have been published. All these studies aim to provide knowledge with the ultimate aim of reducing the increasing number of deaths. However, these studies also introduce subtle methodological fact...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,评审
doi:
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:To analyze the factors that determine the risk of morbidity and mortality associated with lung resection in patients with bronchogenic carcinoma. PATIENTS AND METHODS:Prospective multicenter study conducted between October 1, 1993 and September 30, 1997 in the 19 hospitals that make up the Bronchogenic Carci...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s1579-2129(07)60038-x
更新日期:2007-03-01 00:00:00
abstract::We report a case of pleural effusion, pericardial thickening, and pulmonary involvement in a patient with dry cough, dyspnea, edema, and changes in the skin of the lower limbs. Treatment with cabergoline (Sogilen) had been started 4 months earlier. Pleural effusion, pericardial thickening, and impaired pulmonary funct...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s1579-2129(07)60118-9
更新日期:2007-09-01 00:00:00
abstract:OBJECTIVE:Workers in shoe manufacturing have been reported to be at a greater relative risk for bronchogenic carcinoma. Given the implications for our practice setting, we carried out a study to a) clarify whether working in shoe manufacturing is a risk factor for lung cancer and b) detect histological differences betw...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s1579-2129(06)60426-6
更新日期:2005-04-01 00:00:00