Abstract：
:Specific bronchial challenge (SBC) testing is a key technique for diagnosing the origin of occupational asthma (OA). SBC is indicated in specific circumstances, including whenever several agents present in the work environment may be the cause of OA, when new or unusual occupational agents need to be identified, when evidence for legal action is required, or when research is conducted. SBC procedures are not standardized, because of the great diversity of occupational agents and the variety of physical and chemical properties involved. Thus, SBC testing with agents found in fumes, gases or vapors can be administered in special cabins or in closed circuits with continuous monitoring of sub-irritant concentrations. Agents found in dust, most but not all of which have high molecular weights, may be appropriate for routine SBC testing in an allergy laboratory. This paper will treat only these cases. SBC must be formed in specialized centers by experienced personnel, as it is a sophisticated and potentially dangerous technique. We describe a series of 20 patients diagnosed of OA in our unit over the past two years in whom SBC provided an etiologic diagnosis. All were exposed to dust or aerosols at work. The cause was a substance of high molecular weight in 17 cases, and low molecular weight in 3. The procedure used is described and models of bronchial response are discussed.
journal_name
Arch Bronconeumoljournal_title
Archivos de bronconeumologiaauthors
Fraj J,Duce F,Lezaun A,Colás C,Domínguez MA,Abadía MCdoi
10.1016/s0300-2896(15)30546-9subject
Has Abstractpub_date
1997-10-01 00:00:00pages
444-9issue
9eissn
0300-2896issn
1579-2129pii
S0300-2896(15)30546-9journal_volume
33pub_type
杂志文章abstract：:To check the technical specifications of 5 O2 concentrators pertaining to 5 different brands: Mark 4, Zefir, Puritan-Bennet, Drager and MHF prototype. The concentrators worked continuously for 37 days. External filters were cleaned after 400 hours and measurements were taken when theoretical flows were between 1 and 3...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：
更新日期：1995-10-01 00:00:00
abstract：BACKGROUND:The non-adherence to tuberculosis treatment is associated with increased infection, antibiotic resistance, increased costs and death. Our objective was to identify factors associated with lack of completion of conventional treatment for tuberculosis in Peru. PATIENTS AND METHODS:An unmatched case-control st...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/j.arbres.2011.12.008
更新日期：2012-05-01 00:00:00
abstract：:Chronic obstructive pulmonary disease (COPD) and lung cancer (LC) are prevalent diseases and are a leading cause of morbidity and mortality worldwide. There is strong evidence to show that COPD is an independent risk factor for LC. Chronic inflammation plays a significant pathogenic role in COPD comorbidities, particu...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,评审
doi：10.1016/j.arbres.2015.07.003
更新日期：2016-01-01 00:00:00
abstract：:Exogenous lipoid pneumonia (ELP) is a rare (incidence 1.0%-2.5%), often under-diagnosed disease, caused by the aspiration and accumulation of exogenous lipids within the pulmonary alveoli. Various cases have been described due to inhalation of lubricants via the nasal passages and oropharynx, aspiration of mineral oil...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/j.arbres.2014.09.002
更新日期：2015-07-01 00:00:00
abstract：INTRODUCTION:Pulse transit time (PTT) is the time that a pulse wave takes to travel between two different arterial points, and may be useful in estimating blood pressure. This noninvasive technique, which does not add any cost to the procedure, offers the advantage of avoiding 'arousals' during sleep measurement as occ...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/j.arbres.2013.12.001
更新日期：2014-07-01 00:00:00
abstract：OBJECTIVE:To compare automatic and manual analysis of neurological and respiratory variables obtained with the SomnoStar alpha 4100, a 16-channel polysomnographic system. PATIENTS AND METHOD:Twenty-eight patients suspected of obstructive sleep apnea-hypopnea syndrome were enrolled and given conventional polysomnograph...
journal_title：Archivos de bronconeumologia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0300-2896(03)75452-0
更新日期：2003-12-01 00:00:00
abstract：:Pulmonary alveolar proteinosis (PAP) is a rare disease characterized by the accumulation of surfactant-like lipoproteinaceous material in the distal air spaces and terminal bronchi, which may lead to impaired gas exchange. This accumulation of surfactant is due to decreased clearance by the alveolar macrophages. Its p...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,评审
doi：10.1016/j.arbres.2015.02.003
更新日期：2015-07-01 00:00:00
abstract：OBJECTIVES:Although an association between uric acid (UA) levels and obstructive sleep apnea (OSA) has been reported, the effect of continuous positive airway pressure (CPAP) on this measure is yet unclear. We aimed to investigate the effect of CPAP therapy on serum UA levels in patients with OSA. METHODS:We conducted...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.arbres.2018.09.012
更新日期：2019-04-01 00:00:00
abstract：:We report the case of a 61-year-old man with amyotrophic lateral sclerosis presenting with respiratory failure requiring long-term mechanical ventilation. Diagnostic difficulties are discussed along with the circumstances that give rise to suspicion of neuromuscular disease in a context of respiratory failure of unkno...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,评审
doi：10.1016/s0300-2896(15)30324-0
更新日期：1999-01-01 00:00:00
abstract：:Infection of the larynx by Candida is rare and usually accompanies lung or disseminated candidiasis. The incidence of isolated laryngeal candidiasis (ILC) is low, although it may be underestimated. We describe 2 patients with ILC confirmed during autopsy: a 45-years-old male with pulmonary fibrosis and a 4-years-old g...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/s0300-2896(15)30789-4
更新日期：1996-04-01 00:00:00
abstract：:Pulmonary neoplasms can deposit malignant cells in the pleural cavity by a variety of mechanisms, depending not only on histological type but also on clinical stage. We investigated the effect on survival rate of a finding of malignant cells in pleural lavage. We also investigated the effect of the presence of pleural...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：
更新日期：1996-08-01 00:00:00
abstract：:The main causes of pleural fluid drainage failure are known to be the formation of fibrin septa, increased viscosity in pleural fluid and inappropriate placement of chest tubes. Reports also tell us that such problems can be solved by using ultrasound as a guide for tube placement and by infusing intrapleural fibrinol...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：
更新日期：1996-12-01 00:00:00
abstract：:Proliferating cell nuclear antigen (PCNA) is a 36 kD nuclear protein involved in DNA replication that is believed to provide an indication of proliferation in some neoplasms. This study analyzes PCNA expression in 24 cases of primary non-small cell lung cancer using monoclonal PC-10 antibodies in paraffin embedded mat...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/s0300-2896(15)30798-5
更新日期：1996-03-01 00:00:00
abstract：OBJECTIVE:To validate a cardiorespiratory polygraphy system (BITMED NGP 140) by comparing it to conventional polysomnography in the diagnosis of sleep apnea-hypopnea syndrome. PATIENTS AND METHODS:Polysomnography and cardio-respiratory polygraphy were performed simultaneously on 103 consecutive patients referred becau...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/s1579-2129(06)60400-x
更新日期：2005-02-01 00:00:00
abstract：:Chlamydia pneumoniae has often been implicated in respiratory tract infections concomitant with other pathogens. Although this agent has also been associated with other nonrespiratory diseases, to our knowledge it has never been described with autoimmune hemolytic anemia. We present a case of pneumonia in which C. pne...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,评审
doi：10.1016/s0300-2896(15)30772-9
更新日期：1996-05-01 00:00:00
abstract：OBJECTIVE:To describe our experience in managing patients with Duchenne muscular dystrophy. PATIENTS AND METHODS:We analyzed the following variables in a group of 27 patients with Duchenne muscular dystrophy: arterial blood gases, lung function before and after mechanical ventilation, oxygen saturation (measured by pu...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/s1579-2129(07)60127-x
更新日期：2007-10-01 00:00:00
abstract：UNLABELLED:The diaphragm seems to undergo adaptive structural change in chronic obstructive pulmonary disease. The possibility of obtaining muscle specimens is limited, however, particularly when respiratory function is severely affected. OBJECTIVE:To assess the viability of a new technique for obtaining diaphragm mus...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/s0300-2896(15)30228-3
更新日期：2000-01-01 00:00:00
abstract：:One-third of the world-wide population currently presents latent tuberculosis infection (LTI). In Spain, TB is situated as the third disease of mandatory notification. The standard technique for the diagnosis of ITL is the tuberculin test (PPD), although its most important drawback is its specificity since the protein...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,评审
doi：10.1016/j.arbres.2011.06.018
更新日期：2011-10-01 00:00:00
abstract：OBJECTIVE:To study the microbiology of cystic fibrosis in our hospital for the period from 1985 to 1992. MATERIAL AND METHODS:The number of samples analyzed totalled 1,034, most of which were sputum and nasopharyngeal aspirates belonging to 113 patients (49 women and 64 men). The average age was 10 years (range: 15 da...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：
更新日期：1995-12-01 00:00:00
abstract：OBJECTIVE:Although altered vascular permeability and edema of the bronchial mucosa are associated with asthma attack, their influence on its severity remains unknown. We address this issue by comparing relative indices for the concentration of albumin (RIAlb) and alpha2-macroglobulin (RIalpha2M) in induced sputum and p...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/s1579-2129(06)60232-2
更新日期：2005-06-01 00:00:00
abstract：:A 63-year-old woman with follicular bronchiolitis presenting as diffuse interstitial pneumopathy is described. Diagnosis was made by open lung biopsy and the patient was treated in our department until death. The course of disease and response to treatment was similar to that observed in cases of idiopathic pulmonary ...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,评审
doi：
更新日期：1994-10-01 00:00:00
abstract：INTRODUCTION:In recent years, there has been debate regarding the diagnostic accuracy of computed tomography (CT) in the identification of lung metastases and the need for lung palpation to determine the number of metastatic nodules. The aim of this study was to determine in which patients the CT scan was more effectiv...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/j.arbres.2013.05.006
更新日期：2013-12-01 00:00:00
abstract：:We assessed the clinicopathological features of solitary fibrous tumors of the pleura in a case series comprising 30 patients (20 women, 66.6%) with a mean age of 58.39 years. Forty-five percent of the cases were asymptomatic. In 70% of the cases the tumors arose in the visceral pleura. Twenty percent presented multip...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,评审
doi：10.1016/s1579-2129(06)60124-9
更新日期：2006-02-01 00:00:00
abstract：INTRODUCTION:Asthma is an inflammatory disorder of the airways and the symptoms of asthma could be exacerbated by Mycoplasma pneumoniae infection. Interleukin-2 and interleukin-4 have been implicated in immune and inflammatory reactions. We examined the associations of IL2 and IL4 polymorphisms and expression with the ...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/j.arbres.2014.11.004
更新日期：2015-11-01 00:00:00
abstract：:Bronchiectasis is the end result of several different diseases that share principles of management. The clinical course usually involves chronic bronchial infection and inflammation, which are associated with progression. The cause of bronchiectasis should always be investigated, particularly when it can be treated. W...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,实务指引
doi：10.1157/13128330
更新日期：2008-11-01 00:00:00
abstract：OBJECTIVE:The bronchial challenge test is commonly used to diagnose asthma but it is a tedious, time-consuming procedure. Although in recent years, several shortened methods have been proposed, it has been shown that they can give rise to exaggerated bronchoconstriction. The aims of the present study were a) to determi...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：
更新日期：2008-08-01 00:00:00
abstract：BACKGROUND:Results supporting the use and the effectiveness of positive expiratory, pressure devices in chronic obstructive pulmonary disease (COPD) patients are still controversial, We have tested the hypothesis that adding TPEP or IPPB to standard pharmacological therapy may provide additional clinical benefit over, ...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.arbres.2013.07.019
更新日期：2014-01-01 00:00:00
abstract：OBJECTIVE:Retrospective study on the relation between the use of blood products and survival rates in patients treated surgically for stage I non-small cell lung cancer (NSCLC). PATIENTS AND METHODS:The study included 856 patients who underwent surgical resection from 1969 to 2000 for stage I NSCLC, classified histolo...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/s1579-2129(06)60267-x
更新日期：2005-09-01 00:00:00
abstract：:Sixty patients diagnosed as having chronic respiratory diseases were surveyed in order to establish how many knew the name of their disease, the medications they were taking, the name of the medical specialty dedicated to treating their condition and the nature of spirometry. Only 23 patients (38%) knew the name of th...
journal_title：Archivos de bronconeumologia
pub_type： 杂志文章
doi：10.1016/s0300-2896(15)31111-x
更新日期：1994-03-01 00:00:00
abstract：:Conventional polysomnography (CPS) is a complex, costly procedure that is not widely available, meaning that it is difficult to apply it in patients suspected of having obstructive sleep apnea syndrome (OSAS). Various procedures have therefore been proposed for screening candidates for CPS. We studied the usefulness o...
journal_title：Archivos de bronconeumologia
pub_type： 临床试验,杂志文章
doi：
更新日期：1996-11-01 00:00:00
