Treatment of Adult Primary Alveolar Proteinosis.


:Pulmonary alveolar proteinosis (PAP) is a rare disease characterized by the accumulation of surfactant-like lipoproteinaceous material in the distal air spaces and terminal bronchi, which may lead to impaired gas exchange. This accumulation of surfactant is due to decreased clearance by the alveolar macrophages. Its primary, most common form, is currently considered an autoimmune disease. Better knowledge of the causes of PAP have led to the emergence of alternatives to whole lung lavage, although this is still considered the treatment of choice. Most studies are case series, often with limited patient numbers, so the level of evidence is low. Since the severity of presentation and clinical course are variable, not all patients will require treatment. Due to the low level of evidence, some objective criteria based on expert opinion have been arbitrarily proposed in an attempt to define in which patients it is best to initiate treatment.


Arch Bronconeumol


Rodríguez Portal JA




Has Abstract


2015-07-01 00:00:00














  • Management of tracheobronchial amyloidosis with therapeutic bronchoscopic techniques.

    abstract::Amyloidosis is a systemic disease caused by abnormal deposition of amyloid material that is detected with Congo red staining and is difficult to diagnose. Involvement of the tracheobronchial tree is rare and is a challenge for pulmonologists because of the wide differential diagnosis of this disease. We present two ca...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Berraondo J,Novella L,Sanz F,Lluch R,de Casimiro E,Lloret T

    更新日期:2013-05-01 00:00:00

  • Internal consistency and validity of the Spanish version of the "Quebec Sleep Questionnaire" quality-of-life questionnaire for obstructive sleep apnea.

    abstract:INTRODUCTION:There is no specific health-related quality of life (HRQL) questionnaire that has been validated in Spanish for its use in patients with sleep apnea-hypopnea syndrome (SAHS). The objective of the present study was to validate the Spanish version of the Quebec Sleep Questionnaire (QSQ). PATIENTS AND METHOD...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Catalán P,Martínez A,Herrejón A,Chiner E,Martínez-García MÁ,Sancho-Chust JN,Peris R,Senent C,Blanquer R,Tomás JM

    更新日期:2012-04-01 00:00:00

  • Characteristics of candidates for lung transplantation due to chronic obstructive pulmonary disease and alpha-1 antitrypsin deficiency emphysema.

    abstract:INTRODUCTION:COPD and emphysema due to alpha-1 antitrypsin deficiency (AATD) are the first and fourth indications for lung transplantation worldwide, respectively. Despite this, there is little information regarding the health status of these patients at the time of transplantation. METHODS:Patients who received a lun...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Giacoboni D,Barrecheguren M,Esquinas C,Rodríguez E,Berastegui C,López-Meseguer M,Monforte V,Bravo C,Pirina P,Miravitlles M,Román A

    更新日期:2015-08-01 00:00:00

  • Endobronchial valves in the treatment of persistent air leak, an alternative to surgery.

    abstract:INTRODUCTION:Persistent air leak is frustrating for both patients and physicians, above all leaks with a high risk of surgery. Insertion of endobronchial valves could be an alternative to surgery. The aim of this study is to describe our experience in these valves and analyse their efficacy in a series of patients with...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Cordovilla R,Torracchi AM,Novoa N,Jiménez M,Aranda JL,Varela G,Barrueco M

    更新日期:2015-01-01 00:00:00

  • [Clinical efficacy of moxifloxacin in the treatment of exacerbations of chronic bronchitis: a systematic review and meta-analysis].

    abstract:OBJECTIVE:As the research undertaken to date on the efficacy of the new antibiotics in the treatment of exacerbations of chronic bronchitis has taken the form of trials designed to demonstrate equivalence, we have no data on the advantages associated with the use of these new drugs with greater bactericidal activity. O...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章,meta分析,评审


    authors: Miravitlles M,Molina J,Brosa M

    更新日期:2007-01-01 00:00:00

  • Manual Versus Digital Aspiration for First-Line Treatment of Primary Spontaneous Pneumothorax. The AMVADI Study: A Randomized Clinical Trial.

    abstract:INTRODUCTION:The effectiveness of needle aspiration in the initial treatment of primary spontaneous pneumothorax has been widely studied. The objective of this research was to compare digital with manual aspiration in a randomized clinical trial. METHODS:We designed a blinded parallel-group randomized clinical trial w...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Aguinagalde B,Zabaleta J,Fernández-Monge A,Lopez I,Izquierdo JM,Redin JA,López D,Emparanza JI

    更新日期:2020-10-01 00:00:00

  • [Sleep apnea-hypopnea syndrome in the elderly].

    abstract::The population pyramid is changing due to the increasing longevity of the population, making it a priority to have better knowledge of those diseases that have an increasingly major impact in advanced age. Sleep apnea-hypopnea syndrome (SAHS) affects 15-20% of individuals over 65 years. However, despite this high prev...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章,评审


    authors: Martínez-García MA,Durán-Cantolla J,Montserrat JM

    更新日期:2010-09-01 00:00:00

  • Official Statement of the Spanish Society of Pulmonology and Thoracic Surgery (SEPAR) on Electronic Cigarettes and IQOS®.

    abstract::The use of novel tobacco products, particularly the electronic cigarette (EC) and partial tobacco combustion devices (HnB systems: Heat not Burn), has increased exponentially, particularly among adolescents and young people. The health authorities and scientific societies have shown concern about issues surrounding sa...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章,评审


    authors: Signes-Costa J,de Granda-Orive JI,Ramos Pinedo Á,Camarasa Escrig A,de Higes Martínez E,Rábade Castedo C,Cabrera César E,Jiménez-Ruiz CA

    更新日期:2019-11-01 00:00:00

  • [Sleep disorders in patients on a kidney transplant waiting list].

    abstract:OBJECTIVE:To evaluate the prevalence of sleep disorders in patients awaiting kidney transplants compared to a control group. PATIENTS AND METHODS:We carried out an observational study of 23 patients on a kidney transplant waiting list in comparison with 20 healthy volunteers matched for age, sex, and body mass index (...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Jurado Gámez B,Martín-Malo A,Fernández Marín MC,Rodríguez-Benot A,Pascual N,Muñoz Cabrera L,Aljama P

    更新日期:2008-07-01 00:00:00

  • Primary ciliary dyskinesia: clinical criteria indicating ultrastructural studies.

    abstract:INTRODUCTION:Primary ciliary dyskinesia (PCD) is a congenital disease characterized by impaired ciliary function, which involves a wide range of symptoms that are mainly respiratory. Recent articles that base diagnosis on ciliary ultrastructural studies have estimated its prevalence to be 1/10,000 newborns, which is hi...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Busquets RM,Caballero-Rabasco MA,Velasco M,Lloreta J,García-Algar Ó

    更新日期:2013-03-01 00:00:00

  • [Prognostic value of positive cytology found in pleural lavage of patients with cancer of the lung. Prospective study].

    abstract::Pulmonary neoplasms can deposit malignant cells in the pleural cavity by a variety of mechanisms, depending not only on histological type but also on clinical stage. We investigated the effect on survival rate of a finding of malignant cells in pleural lavage. We also investigated the effect of the presence of pleural...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Arnau Obrer A,Cantó Armengod A,Martín Díaz E,Navarro Ibáñez R,Ramón Capilla M,García Aguado R,Martorell Cebollada M

    更新日期:1996-08-01 00:00:00

  • [Annual review of Archivos de Neumología in interventional pneumology, interstitial diseases and lung transplantation].

    abstract::A review has been made of original articles on invasive pneumology techniques, interstitial diseases and lung transplantation, published in the Archivos de Bronconeumología during the year 2008. We have selected the publication by Martínez-Olondrins et al on the mediastinal staging of bronchogenic carcinoma by ...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章,评审


    authors: Disdier C,Bollo E,Morales P,Montero C

    更新日期:2009-01-01 00:00:00

  • Comparing Spirometric Reference Values From Childhood to Old Age Estimated by LMS and Linear Regression Models.

    abstract:BACKGROUND:Proper reference values for lung function testing are essential for achieving adequate interpretations. The LMS procedure (lambda, mu, sigma) permits continuous analyses of entire populations avoiding gaps in the transition between childhood and adulthood. It also allows more precise calculations of average ...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Martínez-Briseño D,Gochicoa-Rangel L,Torre-Bouscoulet L,Cid-Juárez S,Fernández-Plata R,Martínez-Valdeavellano L,Chapela-Lara S,Del Río-Hidalgo R,Pérez-Padilla R

    更新日期:2020-02-29 00:00:00

  • [Prognostic factors and outcome of thymectomy in 80 cases of myasthenia gravis].

    abstract:OBJECTIVES:To analyze the results of thymectomy in our series of patients with myasthenia gravis (MG) and to study the influence of the most common prognostic factors. MATERIAL AND METHODS:Eighty MG patients over a period of 23 years underwent thymectomy consecutively in our hospital. Preoperative assessment included ...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Vázquez-Pelillo J,Gil Alonso J,Díaz-Agero P,García Sánchez-Girón J,Roca Serrano R,Díez Tejedor E,Casillas Pajuelo M

    更新日期:2001-04-01 00:00:00

  • [Treatment of asthma with antileukotrienes and Churg-Strauss syndrome].

    abstract::Since antileukotriene treatment for asthma was introduced, there has been debate about whether such therapy can lead to Churg-Strauss Syndrome (CSS) or whether CSS is simply inhibited by the use of steroids, as various authors have suggested. We report a case in which we suspected CSS in a patient with bronchopulmonar...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章,评审


    authors: Sala Félix J,Pereiro Alonso ME,Salas Antón C

    更新日期:2001-01-01 00:00:00

  • [Prevalence and distribution of asbestos lung residue in a Spanish urban population].

    abstract:INTRODUCTION:The purpose of the present study is to analyse the prevalence and distribution of asbestos lung residue in the Barcelona urban population. MATERIAL AND METHODS:Lung autopsy samples were obtained from 35 individuals who had lived in Barcelona. The close family were interviewed in order to rule out asbestos...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Velasco-García MI,Recuero R,Cruz MJ,Panades R,Martí G,Ferrer J

    更新日期:2010-04-01 00:00:00

  • [Pulmonary inflammatory pseudotumor. Its diagnosis by fine-needle aspiration puncture].

    abstract::Cytological characteristics are reported in the case of a 20-years-old male with pulmonary inflammatory pseudotumor (PIP) diagnosed by fine-needle aspiration (FNA) and later confirmed histologically. The patient presented a large tumor on the lower lobe of the right lung with hemoptysis, hemothorax and secondary acute...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章,评审


    authors: Ramos Fernández V,Prieto Rodríguez M,Navarro Hervas M,Camañas Sanz A,Saiz Paches V,Vera-Sempere FJ

    更新日期:1994-04-01 00:00:00

  • [A comparison of lymphocyte populations of the blood and bronchoalveolar lavage in AIDS patients].

    abstract::Changes in cell immunity made manifest by decreases in blood levels of CD4 T cells is the main indicator of progressing HIV infection. The decrease in these lymphocytes, as well as in the CD4/CD8 index and increases in suppressant or cytotoxic CD8 cells can be detected in bronchoalveolar (BAL) lung samples. It is not ...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Fernández E,León P,Blanquer R,Marín M,Artero A,Pinilla A

    更新日期:1996-06-01 00:00:00

  • [Costs of chronic obstructive pulmonary disease in Spain. Estimation from a population-based study].

    abstract:OBJECTIVE:In the studies carried out to date, the cost of chronic obstructive pulmonary disease (COPD) may have been overestimated due to the inclusion of previously diagnosed patients seeking medical attention for their symptoms. As a result, the severity of the cases included in these studies may have been greater th...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Masa JF,Sobradillo V,Villasante C,Jiménez-Ruiz CA,Fernández-Fau L,Viejo JL,Miravitlles M

    更新日期:2004-02-01 00:00:00

  • [Effects of nasal continuous positive airway pressure on lung function in patients with sleep obstructive apnea syndrome].

    abstract::Sixty-one patients with obstructive sleep apnea syndrome (OSAS), 26 of whom also had chronic obstructive pulmonary disease (COPD), received treatment by nasal continuous positive airways pressure (nCPAP). To evaluate the effects of this device on daytime lung function, we analyzed pulmonary function tests before treat...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Vázquez Oliva R,Cano Gómez S,Capote Gil F,Sánchez Armengol MA,Carmona Bernal C,Castillo Gómez J

    更新日期:1995-01-01 00:00:00

  • Reliability of an analysis method for measuring diaphragm excursion by means of direct visualization with videofluoroscopy.

    abstract:OBJECTIVE:The purpose of this study was to verify the reproducibility between two different observers of an analysis method for diaphragmatic displacement measurements using direct visualization with videofluoroscopy. PATIENTS AND METHODS:29 mouth breathing children aged 5 to 12 years from both genders were analyzed. ...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Yi LC,Nascimento OA,Jardim JR

    更新日期:2011-06-01 00:00:00

  • [Management of pleural disease].

    abstract::In view of the presentations in the First National Forum of Trainee Pneumologists, the present article focuses on infectious pleural effusions and on the study of possible markers of malignant disease in asbestos-exposed individuals. The yield of the distinct techniques for the diagnosis of tuberculous pleural effusio...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Rodríguez-Panadero F,Pérez MA,Moya MA,Cruz MI

    更新日期:2009-01-01 00:00:00

  • [Risk factors in bronchogenic carcinoma surgery].

    abstract:OBJECTIVE:To analyze the factors that determine the risk of morbidity and mortality associated with lung resection in patients with bronchogenic carcinoma. PATIENTS AND METHODS:Prospective multicenter study conducted between October 1, 1993 and September 30, 1997 in the 19 hospitals that make up the Bronchogenic Carci...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Duque JL,Rami-Porta R,Almaraz A,Castanedo M,Freixinet J,Fernández de Rota A,López Encuentra A,Grupo Cooperativo del Carcinoma Broncogénico SEPAR.

    更新日期:2007-03-01 00:00:00

  • Clinical audit of patients hospitalized due to COPD exacerbation. MAG-1 Study.

    abstract:UNLABELLED:Hospitalizations for acute exacerbation of COPD (AECOPD) generate high consumption of health resources, frequent readmissions and high mortality. The MAG -1 study aims to identify critical points to improve the care process of severe AECOPD requiring hospitalization. METHODS:Observational study, with review...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章,多中心研究


    authors: Escarrabill J,Torrente E,Esquinas C,Hernández C,Monsó E,Freixas M,Almagro P,Tresserras R,en nombre del equipo del Plan Director de las Enfermedades del Aparato Respiratorio (PDMAR) y del grupo colaborador del proyecto MAG-1.

    更新日期:2015-10-01 00:00:00

  • Can pulse transit time be useful for detecting hypertension in patients in a sleep unit?

    abstract:INTRODUCTION:Pulse transit time (PTT) is the time that a pulse wave takes to travel between two different arterial points, and may be useful in estimating blood pressure. This noninvasive technique, which does not add any cost to the procedure, offers the advantage of avoiding 'arousals' during sleep measurement as occ...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Gómez García MT,Troncoso Acevedo MF,Rodriguez Guzmán M,Alegre de Montaner R,Fernández Fernández B,del Río Camacho G,González-Mangado N

    更新日期:2014-07-01 00:00:00

  • Prevalence and Determinants of COPD in Spain: EPISCAN II.

    abstract:BACKGROUND:Two previous national epidemiological studies, IBERPOC in 1997 and EPISCAN in 2007, determined the COPD burden in Spain. Changes in demographics and exposure to risk factors demand the periodic update of COPD prevalence and its determinants. METHODS:EPISCAN II aimed to estimate the prevalence of COPD in the...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Soriano JB,Alfageme I,Miravitlles M,de Lucas P,Soler-Cataluña JJ,García-Río F,Casanova C,Rodríguez González-Moro JM,Cosío BG,Sánchez G,Ancochea J

    更新日期:2021-01-01 00:00:00

  • [Hemodynamic study: indications for right- and left-sided catheterization in the diagnosis and follow-up of pulmonary hypertension].

    abstract::Pulmonary artery hypertension (PAH) is a category of pulmonary hypertension consisting of mean pulmonary artery pressure greater than 25 mmHg at rest, with normal pulmonary capillary occlusion pressure (less than 15 mmHg) and pulmonary vascular resistance greater than 3 Wood units. The diagnosis of PAH is made through...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章,评审


    authors: Amaro Cendón A

    更新日期:2011-01-01 00:00:00

  • [Cost-effectiveness study of the diagnosis of pleural effusion in chest diseases outpatient clinic].

    abstract:OBJECTIVE:To evaluate the diagnostic efficacy of pleural procedures, safety, delay and cost of the diagnosis of pleural effusion (PE) by analysing the parameters that are dependent on the area of patient management (outpatient or inpatient). PATIENTS AND METHODS:Prospective non-randomized study. Two groups were establ...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Botana Rial M,Leiro Fernández V,Represas Represas C,Pallarés Sanmartín A,Del Campo Pérez V,Fernández-Villar A

    更新日期:2010-09-01 00:00:00

  • Activating and resistance mutations of the epidermal growth factor receptor (EGFR) gene and non-small cell lung cancer: a clinical reality.

    abstract::In non-small cell lung cancer, the EGFR gene mutations identify a patient sub-population with different clinical characteristics and treatment responses to those that do not have these mutations. There are mutations that derive in increased sensitive to EGFR targeted therapy, as well as mutations that result in resist...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Taus A,Vollmer I,Arriola E

    更新日期:2011-02-01 00:00:00

  • Medical Care According to Risk Level and Adaptation to Spanish COPD Guidelines (Gesepoc): The Epoconsul Study.

    abstract:INTRODUCTION:EPOCONSUL is the first national audit to analyze medical care for COPD in pulmonology departments in Spain. The main objective was to perform a retrospective analysis to determine the distribution of GesEPOC 2017 COPD risk levels and to evaluate clinical activity according to the new recommendations. MATE...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Calle Rubio M,Rodríguez Hermosa JL,Soler-Cataluña JJ,López-Campos JL,Alcazar Navarrete B,Soriano JB,Rodríguez Gónzalez-Moro JM,Fuentes Ferrer ME,Miravitlles M,y el Grupo Epoconsul.

    更新日期:2018-05-01 00:00:00