[Changes in the acid-base equilibrium of pleural fluid during the first 2 hours after thoracentesis].


OBJECTIVE:The aim of this study was to assess changes in the acid-base equilibrium of pleural fluid during the first 2 hours after thoracentesis and to determine whether, as with arterial blood, it is important to keep the fluid on ice. PATIENTS AND METHODS:A prospective, descriptive, comparative study was performed in 53 consecutive patients with pleural effusion. Thoracentesis was performed and pleural fluid was collected in 5 heparinized syringes to determine the pH, PO2, and PCO2 at baseline and at 30, 60, 90, and 120 minutes. In the first 26 patients, pleural fluid was collected in a further 4 syringes that were kept on ice prior to performing the same measurements at 30, 60, 90, and 120 minutes. RESULTS:The patients had a mean (SD) age of 70 (14) years, 66% were smokers, 72% were men, 63% had right-sided pleural effusion, 85% had unilateral effusion, and 15% had massive effusion. In 10 patients the effusion was a transudate, in 35 it was lymphocytic, and in 8 it was neutrophilic. The etiology was benign in 34 cases and neoplastic in 19 cases. The baseline pH was 7.35 (0.1) and baseline values of PO2 and PCO2 were 57.8 (20) mm Hg and 53.7 (15) mm Hg, respectively. No significant changes were observed in the first 2 hours for either pH or PCO2, whereas PO2 did undergo a significant change over this period. The difference between the baseline value and the value obtained at 120 minutes was 0.005 (0.02) for pH, 12.5 (19) mm Hg for PO2, and 0.8 (3) mm Hg for PCO2, with correlation coefficients of 0.97, 0.49, and 0.98, respectively. Comparison of values by simple regression analysis did not reveal a significant difference in the changes in pH, PO2, or PCO2 associated with keeping samples on ice. Multivariate analysis revealed that neoplastic effusion and a higher red blood cell count in pleural fluid had a significant influence on pH changes. CONCLUSIONS:The pH and PCO2 of pleural fluid did not change significantly during the first 2 hours following thoracentesis, whereas PO2 did undergo a significant change. Keeping samples on ice during this period is unnecessary. Only a higher red blood cell count in pleural fluid and neoplastic effusion had a limited effect on changes in the pH of samples from our patients during the first 2 hours following thoracentesis.


Arch Bronconeumol


Haro-Estarriol M,Baldó-Padró X,Lora-Díez M,Rubio-Garay M,Rubio-Goday M,Sebastián-Quetglás F





Has Abstract


2005-11-01 00:00:00














  • [Impact of anemia on COPD].

    abstract::The frequency of anemia may be higher than expected in patients with chronic obstructive pulmonary disease (COPD). Some studies have detected a prevalence of 33%, contrasting with the common idea that associates COPD with secondary polyglobulia. Among the risk factors associated with the development of anemia in these...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: de Miguel Díez Jde M,Martín MJ,Bailón MM,Alvarez-Sala JL

    更新日期:2009-01-01 00:00:00

  • Continuous Positive Airway Pressure Treatment Does not Reduce Uric Acid Levels in OSA Women.

    abstract:OBJECTIVES:Although an association between uric acid (UA) levels and obstructive sleep apnea (OSA) has been reported, the effect of continuous positive airway pressure (CPAP) on this measure is yet unclear. We aimed to investigate the effect of CPAP therapy on serum UA levels in patients with OSA. METHODS:We conducted...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Campos-Rodriguez F,Reyes-Nuñez N,Queipo-Corona C,Sanchez-Armengol A,Jurado-Gamez B,Cordero-Guevara J,Troncoso MF,Abad-Fernandez A,Caballero-Rodriguez J,Martin-Romero M,Encabo-Motiño A,Sacristan-Bou L,Navarro-Esteva J,Somoza-Gon

    更新日期:2019-04-01 00:00:00

  • Spanish Compliance With Guidelines for Prescribing Four Drugs in the Intensive Phase of Standard Tuberculosis Treatment.

    abstract:INTRODUCTION:International and Spanish guidelines recommend a 4-drug regimen in the intensive treatment of tuberculosis (TB). The aim of our study was to determine if these recommendations are followed in Spain, and the factors associated with the use of 3 drugs (standard regimen without ethambutol). METHODOLOGY:Obser...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章,多中心研究


    authors: García-García JM,Rodrigo T,Casals M,Ruiz-Manzano J,Pascual-Pascual T,Caylà JA,Grupo de Trabajo del Programa Integrado de Investigación en Tuberculosis (PIITB).

    更新日期:2016-05-01 00:00:00

  • [Predictors of outcome in blunt chest trauma].

    abstract:INTRODUCTION:Thoracic trauma is often associated with polytrauma. Because mortality is high, the search for prognostic tools is useful. PATIENTS AND METHODS:A total of 108 patients with blunt thoracic trauma, 73 of whom had multiple injuries, were studied in an intensive care unit (ICU). The variables named as potenti...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Virgós Señor B,Nebra Puertas AC,Sánchez Polo C,Broto Civera A,Suárez Pinilla MA

    更新日期:2004-11-01 00:00:00

  • [Effect of intravenous magnesium sulfate on chronic obstructive pulmonary disease exacerbations requiring hospitalization: a randomized placebo-controlled trial].

    abstract:OBJECTIVE:Magnesium sulfate has been shown to have a bronchodilating effect in asthma, but this effect has not been clearly established in the context of chronic obstructive pulmonary disease (COPD). For this reason we investigated the possible bronchodilating effect of magnesium sulfate in COPD exacerbations. PATIENT...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章,随机对照试验


    authors: Abreu González J,Hernández García C,Abreu González P,Martín García C,Jiménez A

    更新日期:2006-08-01 00:00:00

  • [Pulmonary and nonpulmonary alterations in Duchenne muscular dystrophy].

    abstract:OBJECTIVE:To describe our experience in managing patients with Duchenne muscular dystrophy. PATIENTS AND METHODS:We analyzed the following variables in a group of 27 patients with Duchenne muscular dystrophy: arterial blood gases, lung function before and after mechanical ventilation, oxygen saturation (measured by pu...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Güell MR,Avendano M,Fraser J,Goldstein R

    更新日期:2007-10-01 00:00:00

  • [Venous compression ultrasonography of the lower limbs: a diagnostic tool in the hands of pneumologists].

    abstract::Our objective was to study agreement between the compression ultrasound images taken in our respiratory medicine department and the duplex ultrasound images obtained by radiologists at our hospital for patients admitted to our ward with suspected diagnoses of venous thromboembolism.Seventy-eight consecutive patients a...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Arenas Gordillo M,Otero Candelera R,Cayuela Domínguez A,López Campos JL,Barrot Cortés E,González Brazo J,Verano Rodríguez A

    更新日期:2002-04-01 00:00:00

  • Extraskeletal Ewing's sarcoma presenting as a posterior mediastinal mass.

    abstract::The Ewing's sarcoma family of tumors is an uncommon group of malignant neoplasms that may be located in both skeletal and extraskeletal regions. Extraskeletal Ewing's sarcoma (EES) is quite rare and predominantly involves the soft tissues of the trunk or the extremities. Herein, we report the case of a 19-year-old fem...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Halefoglu AM

    更新日期:2013-02-01 00:00:00

  • [Use of gene therapy in a subcutaneous murine model of lung cancer].

    abstract:OBJECTIVE:To assess the effectiveness of in vivo gene therapy to treat subcutaneous tumors generated from murine lung cancer cells. MATERIAL AND METHODS:C57BL/6 mice received subcutaneus injections of 5 x 105 cells from the murine Lewis lung cancer cell line. By 10 days, subcutaneous tumors of approximately 5 mm diame...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Rodrigo Garzón M,Tirapu Fernández de la Cuesta I,Arina Iraeta A,Centelles Llorente MN,Zulueta Francés J

    更新日期:2006-10-01 00:00:00

  • [Limitations of current treatment: unmet needs in the treatment of COPD].

    abstract::In the last few years, considerable interest has been aroused in the treatment of chronic obstructive pulmonary disease (COPD) and the dearth of therapeutic options has been replaced by a far more proactive treatment approach, reflected in the development of the various guidelines and recommendations of the scientific...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章,评审


    authors: de Lucas Ramos P,López Martín S,Rodríguez González-Moro JM

    更新日期:2010-12-01 00:00:00

  • [Prognostic factors and outcome of thymectomy in 80 cases of myasthenia gravis].

    abstract:OBJECTIVES:To analyze the results of thymectomy in our series of patients with myasthenia gravis (MG) and to study the influence of the most common prognostic factors. MATERIAL AND METHODS:Eighty MG patients over a period of 23 years underwent thymectomy consecutively in our hospital. Preoperative assessment included ...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Vázquez-Pelillo J,Gil Alonso J,Díaz-Agero P,García Sánchez-Girón J,Roca Serrano R,Díez Tejedor E,Casillas Pajuelo M

    更新日期:2001-04-01 00:00:00

  • [Isolated laryngeal candidiasis. Description of 2 cases and review of the literature].

    abstract::Infection of the larynx by Candida is rare and usually accompanies lung or disseminated candidiasis. The incidence of isolated laryngeal candidiasis (ILC) is low, although it may be underestimated. We describe 2 patients with ILC confirmed during autopsy: a 45-years-old male with pulmonary fibrosis and a 4-years-old g...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Alba D,Perna C,Molina F,Ortega L,Várquez JJ

    更新日期:1996-04-01 00:00:00

  • [Diffuse interstitial lung disease related to peribronchiolar metaplasia].

    abstract::Peribronchiolar metaplasia is a histologic lesion characterized by fibrosis and bronchiolar epithelial proliferation, affecting peribronchiolar alveolar septa and terminal bronchioles. It has been considered a nonspecific tissue reaction secondary to the action of external factors, such as tobacco smoke and microbes, ...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Cano-Jiménez E,Molina-Molina M,Ramírez J,Sánchez M,Aliaga JL,Xaubet A

    更新日期:2009-01-01 00:00:00

  • [Trends in the prevalence of tuberculosis among six-year-olds in Albacete (Spain)].

    abstract:OBJECTIVES:To analyze the prevalence and evolution of tuberculous infection among 6-year-olds in Albacete and its relation to socioeconomic status of the family. METHOD:A tuberculin test (2UT RT-23 Tween 80) was given to 6-year-old school children in and around Albacete in 1992 and 1999. We calculated the prevalence o...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Haro M,Vizcaya M,Andicoberry Martínez MJ,Cebrián Villodre E,Chocano De La Encarnación H,García Navarro I,García Piñero MP,Jiménez López J,Haro Estarriol M,López Fuster MA,Núñez Ares A,Texidó Bruguera A,Tornero Molina A,Turpin L

    更新日期:2002-05-01 00:00:00

  • [Validation of a respiratory polygraphy system in the diagnosis of sleep apnea syndrome].

    abstract:OBJECTIVE:To validate a cardiorespiratory polygraphy system (BITMED NGP 140) by comparing it to conventional polysomnography in the diagnosis of sleep apnea-hypopnea syndrome. PATIENTS AND METHODS:Polysomnography and cardio-respiratory polygraphy were performed simultaneously on 103 consecutive patients referred becau...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Candela A,Hernández L,Asensio S,Sánchez-Payá J,Vila J,Benito N,Romero S

    更新日期:2005-02-01 00:00:00

  • [Pulmonary circulation: what has 2010 brought?].

    abstract::In both thromboembolic disease and pulmonary hypertension, 2010 has been a prodigious year for interesting publications. Some data have helped to elucidate the factors associated with a greater risk of thromboembolic disease, such as long journeys and certain polymorphisms. New recommendations on diagnosis have been m...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Gómez García T,de Miguel Díez J,Baloira Villar A

    更新日期:2011-01-01 00:00:00

  • [Diagnostic value of quantitative cultures of endotracheal aspirate in ventilator-associated pneumonia: a multicenter study].

    abstract:OBJECTIVE:To study the validity of quantitative cultures of tracheal aspirate (TA) in comparison with the plugged telescoping catheter (PTC) for the diagnosis of mechanical ventilator-associated pneumonia. METHOD:Prospective multicenter study enrolling patients undergoing mechanical ventilation for longer than 72 hour...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章,多中心研究


    authors: Valencia Arango M,Torres Martí A,Insausti Ordeñana J,Alvarez Lerma F,Carrasco Joaquinet N,Herranz Casado M,Tirapu León JP,Grupo de Estudio de la Neumonía Relacionada con Ventilación Mecánica.,Grupo de Trabajo de Enfermedades Infecciosas

    更新日期:2003-09-01 00:00:00

  • [A study of 73 cases of bronchial tuberculosis].

    abstract::We reviewed 73 cases of bronchial tuberculosis (59 adults and 14 children) diagnosed between 1973 and 2000 using histologic and bacteriologic criteria. The most frequent symptom was cough. Radiographic studies showed an alveolar pattern in 35 cases and obstructive pneumonitis or atelectasis in 28 cases. Endoscopy resu...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Miguel Campos E,Puzo Ardanuy C,Burgués Mauri C,Castella Riera J

    更新日期:2008-05-01 00:00:00

  • [Analysis of respiratory muscle structure and tumor necrosis and insulin-like growth factor expression in chronic obstructive pulmonary disease: are samples valid if obtained during thoracotomy performed because of localized pulmonary neoplasia?].

    abstract:OBJECTIVE:Various methods have been used to obtain samples to study the structure of human respiratory muscles and the expression of diverse substances in them. Samples are most often obtained from autopsies, from muscle biopsies during thoracotomy performed because of a localized pulmonary lesion (TLL), and from ambul...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Casadevall C,Coronell C,Minguella J,Blanco L,Orozco-Levi M,Barreiro E,Broquetas J,Gea J

    更新日期:2004-05-01 00:00:00

  • [A technical evaluation of 5 brands of O2 concentrators. The Asturias Project].

    abstract::To check the technical specifications of 5 O2 concentrators pertaining to 5 different brands: Mark 4, Zefir, Puritan-Bennet, Drager and MHF prototype. The concentrators worked continuously for 37 days. External filters were cleaned after 400 hours and measurements were taken when theoretical flows were between 1 and 3...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Diego González EG,Méndez Lanza A,Mosquera Pestaña JA

    更新日期:1995-10-01 00:00:00

  • Activating and resistance mutations of the epidermal growth factor receptor (EGFR) gene and non-small cell lung cancer: a clinical reality.

    abstract::In non-small cell lung cancer, the EGFR gene mutations identify a patient sub-population with different clinical characteristics and treatment responses to those that do not have these mutations. There are mutations that derive in increased sensitive to EGFR targeted therapy, as well as mutations that result in resist...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Taus A,Vollmer I,Arriola E

    更新日期:2011-02-01 00:00:00

  • Comparison of intermittent positive pressure breathing and temporary positive expiratory pressure in patients with severe chronic obstructive pulmonary disease.

    abstract:BACKGROUND:Results supporting the use and the effectiveness of positive expiratory, pressure devices in chronic obstructive pulmonary disease (COPD) patients are still controversial, We have tested the hypothesis that adding TPEP or IPPB to standard pharmacological therapy may provide additional clinical benefit over, ...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章,随机对照试验


    authors: Nicolini A,Mollar E,Grecchi B,Landucci N

    更新日期:2014-01-01 00:00:00

  • Clinical audit of patients hospitalized due to COPD exacerbation. MAG-1 Study.

    abstract:UNLABELLED:Hospitalizations for acute exacerbation of COPD (AECOPD) generate high consumption of health resources, frequent readmissions and high mortality. The MAG -1 study aims to identify critical points to improve the care process of severe AECOPD requiring hospitalization. METHODS:Observational study, with review...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章,多中心研究


    authors: Escarrabill J,Torrente E,Esquinas C,Hernández C,Monsó E,Freixas M,Almagro P,Tresserras R,en nombre del equipo del Plan Director de las Enfermedades del Aparato Respiratorio (PDMAR) y del grupo colaborador del proyecto MAG-1.

    更新日期:2015-10-01 00:00:00

  • [Cystic fibrosis: a microbiological study over an 8-year period].

    abstract:OBJECTIVE:To study the microbiology of cystic fibrosis in our hospital for the period from 1985 to 1992. MATERIAL AND METHODS:The number of samples analyzed totalled 1,034, most of which were sputum and nasopharyngeal aspirates belonging to 113 patients (49 women and 64 men). The average age was 10 years (range: 15 da...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Ferrer Marcelles A,Bellver Moreira P,Cobos Barroso N,Liñán Cortés S,Codina Grau G,Fernández Pérez F

    更新日期:1995-12-01 00:00:00

  • Impact of a Home Telehealth Program After a Hospitalized COPD Exacerbation: A Propensity Score Analysis.

    abstract:INTRODUCTION:Currently there is lack of data regarding the impact of a home telehealth program on readmissions and mortality rate after a COPD exacerbation-related hospitalization. OBJECTIVE:To demonstrate if a tele-monitoring system after a COPD exacerbation admission could have a favorable effect in 1-year readmissi...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Marcos PJ,Represas Represas C,Ramos C,Cimadevila Álvarez B,Fernández Villar A,Fraga Liste A,Fernández Nocelo S,Quiles Del Río J,Zamarrón Sanz C,Golpe R,Abal Arca J,Calvo Álvarez U,Pértega S,García Comesaña J

    更新日期:2020-06-26 00:00:00

  • Overall Survival Analysis and Characterization of an EGFR Mutated Non-Small Cell Lung Cancer (NSCLC) Population.

    abstract:BACKGROUND:Patients with activating somatic mutations in the Epidermal Growth Factor Receptor (EGFR) have better clinical outcomes when treated with Tyrosine Kinase Inhibitors (TKI) over chemotherapy. However, the impact of the use of TKIs on overall survival outside clinical trials is not well established. OBJECTIVE:...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Aguiar F,Fernandes G,Queiroga H,Machado JC,Cirnes L,Souto Moura C,Hespanhol V

    更新日期:2018-01-01 00:00:00

  • [Thoracic traumatism in a specialized unit. Its epidemiology and morbimortality].

    abstract::Two hundred forty-eight cases of thoracic trauma arriving at our hospital between 1990 and 1992 are analyzed in this report. Injuries were only thoracic in 29% of the cases. The remaining patients presented associated lesions, mainly in the extremities, followed by head injuries. Single or multiple rib fracture, in 19...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Casanova Viudez J,Morán Ovide C,Pac Ferrer J,Mariñán Gorospe J,Izquierdo Elena JM,Rojo Marcos R,Rumbero García JC,Martínez Jáuregui A,Vara Cuadrado F

    更新日期:1994-05-01 00:00:00

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    abstract::Ventilator-associated pneumonia (VAP) is the first cause of mortality due to nosocomial infections in the intensive care unit. Its incidence ranges from 9% to 67% of patients on mechanical ventilation. Risk factors are multiple and are associated with prolonged stays in hospital and intensive care units. Additional co...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章,评审


    authors: Díaz LA,Llauradó M,Rello J,Restrepo MI

    更新日期:2010-04-01 00:00:00

  • Results of a Diagnostic Procedure Based on Multiplex Technology on Dried Blood Spots and Buccal Swabs for Subjects With Suspected Alpha1 Antitrypsin Deficiency.

    abstract:INTRODUCTION:The objective of this analysis was the evaluation of a new national circuit used for diagnosing alpha1 antitrypsin deficiency (AATD) based on multiplex technology using online registration and mail posted samples from dried blood spots (DBS) and buccal swabs. METHODS:This is an observational, ongoing stud...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Lopez-Campos JL,Casas-Maldonado F,Torres-Duran M,Medina-Gonzálvez A,Rodriguez-Fidalgo ML,Carrascosa I,Calle M,Osaba L,Rapun N,Drobnic E,Miravitlles M

    更新日期:2021-01-01 00:00:00

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    abstract::Ever since Sullivan introduced nighttime nasal continuous pressure on the upper airway (CPAP) in 1981 it has been the standard treatment for sleep-hypopnea syndrome (SAHS). However, CPAP is carried out at great expense and is not tolerated by all patients. Moreover, its efficacy is dependent on the degree of complianc...

    journal_title:Archivos de bronconeumologia

    pub_type: 杂志文章


    authors: Alarcón A,León C,Maimó A,Barbé F,Agustí AG,Rodríguez-Roisin R,Granados A,Montserrat JM

    更新日期:1995-02-01 00:00:00