[Use of blood products in patients treated surgically for stage I non-small cell lung cancer].

Abstract:

OBJECTIVE:Retrospective study on the relation between the use of blood products and survival rates in patients treated surgically for stage I non-small cell lung cancer (NSCLC). PATIENTS AND METHODS:The study included 856 patients who underwent surgical resection from 1969 to 2000 for stage I NSCLC, classified histologically according to the current guidelines of the Spanish Society of Pulmonary and Thoracic Surgery (SEPAR). Patients who died in the postoperative period were excluded from the study. A series of clinicopathological variables were recorded, including the perioperative use or not of blood products. Descriptive, univariate, and multivariate statistical analyses were performed. Follow up concluded in December of 2003. RESULTS:One hundred twenty-five patients (14.6%) underwent a perioperative transfusion. A significant association was found between the use of blood products and tumor size (P<.001), pneumectomy (P<.001), and cell type (P<.05). The respective 2, 5, and 10-year survival rates were 78%, 63%, and 54% for the nontransfusion group, and 73%, 59%, and 46% for the transfusion group. Both survival curves were compared and no significant differences were found (P=.23). Multivariate regression analysis included tumor size, patient age, and histologic cell type (squamous cell carcinoma or not); no relation between transfusion and survival was found. CONCLUSIONS:In our series, we found no difference in survival rates for patients with stage I NSCLC after perioperative blood transfusion.

journal_name

Arch Bronconeumol

authors

Peñalver JC,Padilla J,Jordá C,Escrivá J,Cerón J,Calvo V,García A,Pastor J,Blasco E

doi

10.1016/s1579-2129(06)60267-x

keywords:

subject

Has Abstract

pub_date

2005-09-01 00:00:00

pages

484-8

issue

9

eissn

0300-2896

issn

1579-2129

pii

13078649

journal_volume

41

pub_type

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