Abstract：
:We investigated the effects of a weak cutaneous stimulus applied to the digital nerves (prepulse) on the masseter inhibitory reflex (MIR) to electrical stimulation of the mental nerve in nine healthy volunteers. The prepulse stimulus, which had no direct effect on the masseter muscle EMG activity, induced a significant decrement in the area of the second phase of the MIR at interstimulus intervals between 50 and 100 ms. The percentage reduction induced on the inhibitory phase of the MIR was not different from that induced by the same prepulse on the late excitatory phase (R2) of the orbicularis oculi muscle to supraorbital nerve electrical stimulation during voluntary contraction. The effects observed during contraction were significantly less marked than those observed in the blink reflex at rest. We conclude that prepulse inhibition occurs in various brainstem reflexes, is similarly active on excitatory and inhibitory responses, and is reduced during voluntary activation.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Gómez-Wong E,Valls-Solé Jdoi
10.1016/0304-3940(96)12574-xsubject
Has Abstractpub_date
1996-04-26 00:00:00pages
183-6issue
3eissn
0304-3940issn
1872-7972pii
030439409612574Xjournal_volume
208pub_type
杂志文章abstract：:Astrocyte cell cultures were established from human fetal brains and exposed to human recombinant tumor necrosis factor alpha (TNF alpha) and human recombinant interferon gamma (IFN gamma), and the proliferative response was assessed by bromodeoxyuridine-immunostaining technique. TNF alpha showed an inhibitory activit...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(93)90034-i
更新日期：1993-03-05 00:00:00
abstract：:Methamphetamine (METH) has been a worldwide health threat for years. Recent studies have reported that circular RNA (circRNA) are highly abundant and dynamically expressed in brain. However, connections between circRNA and METH-induced neurotoxicity remains indefinite. In the present study, primary cortical neurons we...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2019.02.032
更新日期：2019-05-14 00:00:00
abstract：:Febrile seizures (FSs) are the most common type of convulsions in childhood and complex FSs represent an increased risk for development of temporal lobe epilepsy. The aim of this study was to analyze the anticonvulsant effects of carnosine, an endogenous dipeptide composed of alanine and histidine, on hyperthermia ind...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2014.12.061
更新日期：2015-02-19 00:00:00
abstract：:Autism spectrum disorders are characterized by impaired social and communication skills and seem to result from altered neural development. We sought to determine whether the anatomy of the meninges and extracellular matrix (ECM) is altered in an animal model of autism, the BTBR T+ tf/J mouse. This mouse displays whit...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2011.05.014
更新日期：2011-07-12 00:00:00
abstract：:A common obstacle in clinical management of pathological pain is the poor response to opioid analgesics. We now report that delta9-tetrahydrocannabinol (delta9-THC)-induced antinociception remained effective in rats with pathological pain. The selective central cannabinoid receptor antagonist SR141716A, but not the ge...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(99)00998-2
更新日期：2000-02-11 00:00:00
abstract：:Spinocerebellar ataxia type 17 (SCA17) is an autosomal dominant neurodegenerative disease caused by CAG expansion in the gene encoding the TATA-binding protein (TBP). The neurological features of SCA17 are Purkinje cell loss and gliosis. We have generated SCA17 transgenic mice which recapitulate the patients' phenotyp...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2020.135337
更新日期：2020-11-01 00:00:00
abstract：:Nogo-A is an inhibitor of neurite outgrowth and axonal regeneration after CNS injury. Several functional regions including Nogo-66 were identified to mediate the inhibitory effect of Nogo-A. We have reported that Nogo-66 could promote neural progenitors to differentiate into glial cells. Here we exam three other regio...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2009.04.034
更新日期：2009-07-24 00:00:00
abstract：:Acetylcholine (Ach) has been considered a major neurotransmitter in the inner ear efferent nerve endings. A bioassay analysis has shown that the electrical stimulation of the crossed olivocochlear bundle increased the Ach-like activity in the perilymph. Applying in vivo microdialysis techniques and high-performance li...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(01)02165-6
更新日期：2001-10-05 00:00:00
abstract：:In this report the effects of phencyclidine (PCP) on physiologic variables, local cerebral blood flow (LCBF), and on hippocampal cell damage were measured in a rat model of forebrain ischemia (2-vessel occlusion and hypotension). Ischemia was induced for 10 min. LCBF was determined after 2 min of recirculation, using ...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(88)90701-x
更新日期：1988-09-12 00:00:00
abstract：:Long-term repeated application of morphine induces plasticity changes in sensitive neurons, which represents the neurobiological basis of morphine addiction. Caveolin-1 (Cav-1) is an important scaffolding protein that plays a key role in the regulation of neurostructural plasticity. However, in-depth studies focused o...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2017.11.033
更新日期：2018-02-05 00:00:00
abstract：:Central administration of colchicine causes accumulation of catecholamines in nerve cell bodies and enhances their visualisation in the rat brain by the formaldehyde-glutaraldehyde (FAGLU) histofluorescence method. The detection of catecholamine-containing nerve cells by the FAGLU method was considerably improved in r...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(84)90176-9
更新日期：1984-12-21 00:00:00
abstract：:In an attempt to elucidate the possible mechanisms involved in the development of the thermoregulatory disturbances induced by systemic capsaicin treatment, the effects of 5-HT injected into the preoptic region or into the cisterna magna on the body temperature and on tail skin vasodilation were studied in control and...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(85)80124-5
更新日期：1985-02-28 00:00:00
abstract：:We assessed, by quantitative autoradiography, the density of high-affinity alpha 2-adrenoceptors in hippocampus and frontal cortex sections from 18 patients dying with Alzheimer's disease (AD) in comparison with a control group of 13 matched cases. The full agonist [3H]bromoxidine (UK-14304) was used as a ligand. In A...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(92)90614-d
更新日期：1992-08-03 00:00:00
abstract：:Typical histopathological findings of multiple system atrophy (MSA) have been observed in motor related cortices, in addition to the common areas of the striatum, substantia nigra, olivopontocerebellar pathways, the intermediolateral cell columns of the spinal cord, and the cerebellum. The purpose of this study is to ...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2011.07.015
更新日期：2011-09-08 00:00:00
abstract：:This study used ERPs to determine whether older adults use prosody in resolving early and late closure ambiguities comparably to young adults. Participants made off-line acceptability judgments on well-formed sentences or those containing prosody-syntax mismatches. Behaviorally, both groups identified mismatches, but ...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2010.01.072
更新日期：2010-03-19 00:00:00
abstract：:The effect of antagonists on N-methyl-D-aspartate (NMDA)-induced response was investigated in isolated nucleus tractus solitarii (NTS) neurons freshly isolated from the rat using a conventional pathclamp technique. The NMDA-induced inward current consisted of an initial peak followed by a steady-state component. The c...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(90)90298-n
更新日期：1990-05-31 00:00:00
abstract：:Consummatory successive negative contrast (cSNC) occurs when animals exposed to an unexpected downshift from a high palatable reward (e.g., 32% sucrose solution) to a less preferred one (e.g., 4% sucrose solution) show an abrupt and transient suppression of the consummatory response, compared with control animals that...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2018.07.013
更新日期：2018-09-25 00:00:00
abstract：:The human craniofacial muscles innervated by the facial nerve typically lack muscle spindles. However these muscles have proprioception that participates in the coordination of facial movements. A functional substitution of facial proprioceptors by cutaneous mechanoreceptors has been proposed but at present this alter...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2017.01.016
更新日期：2017-02-15 00:00:00
abstract：:Upregulation of cyclin-dependent kinase 5 (Cdk5) after chronic cocaine administration has led to speculation that Cdk5 plays an important role in drug addiction. However, as Cdk5 involvement is implicated in a variety of neural events, including neuronal development, synaptic plasticity and learning, a specific role i...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2007.02.043
更新日期：2007-04-24 00:00:00
abstract：:Lesch-Nyhan syndrome (LNS), caused by the complete deficiency of hypoxanthine phosphoribosyltransferase (HPRT), is characterized by a neurological deficit, the etiology of which is still unclear. Evidence has accumulated indicating that it reflects dopamine deficiency associated with defective arborization of dopamine...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(01)01716-5
更新日期：2001-04-27 00:00:00
abstract：:The stability of neurotensin (NT) and a potent, long lasting analogue, [D-Trp11]-NT, to rat brain peptidases was compared by incubating the peptides with subcellular fractions (synaptosomes, synaptic membranes) and a purified endopeptidase from rat brain. Degradation of the peptides with time was followed by high perf...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(86)90622-1
更新日期：1986-12-03 00:00:00
abstract：:Hippocampal neurogenesis is potentially implicated in etiology of depression and as the final common mechanism underlying antidepressant treatments. However, decreased neurogenesis has not been demonstrated in depressed patients and, in animals, reduced cytogenesis was shown in healthy rats exposed to stressors, but, ...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2008.03.035
更新日期：2008-05-16 00:00:00
abstract：:Ascending thalamo-telencephalic projection systems have been investigated in an urodele, Triturus alpestris, using the horseradish peroxidase technique. Two separate dorsal thalamic projections onto the telencephalon have been identified; one arises from the posterior dorsal thalamus and terminates in the ipsilateral ...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(86)90235-1
更新日期：1986-07-11 00:00:00
abstract：:Harmonically rich sounds have been shown to be processed more efficiently by the human brain compared to single sinusoidal tones. To control for stimulus complexity as a potentially confounding factor, tones and equally complex spectrally rotated sounds, have been used in the present study to investigate the role of t...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2014.08.035
更新日期：2014-10-03 00:00:00
abstract：:The intergeniculate leaflet (IGL) of the lateral geniculate complex is marked by the presence of neuro-peptide Y-containing neurons that project to the suprachiasmatic nuclei (SCN) of the hypothalamus. In the present study, we demonstrate that both the IGL and SCN in the hamster and rat are specifically delineated by ...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(89)90264-4
更新日期：1989-04-24 00:00:00
abstract：:Temporal patterns of inflammatory cytokine levels reflect the immune-inflammatory role in pathogenic mechanisms of SOD1 animal model of Amyotrophic Lateral Sclerosis (ALS) and these cytokines have important roles in both toxic and protective functions depending on the stage of disease progression in ALS patients. Eryt...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2014.05.001
更新日期：2014-06-27 00:00:00
abstract：:Intramural ganglia of colchicine-injected cat ileum were examined immunohistochemically using antisera to substance P (SP), vasoactive intestinal polypeptide (VIP) and methionine5-enkephalin (ENK). SP- and ENK-like immunoreactive nerve cells were preferentially located in the myenteric ganglia, whereas VIP-like immuno...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(84)90378-1
更新日期：1984-06-01 00:00:00
abstract：:Topical application of horseradish peroxidase (HRP) to the ventral surface of the medulla oblongata revealed various cells with axons terminating near this region. Fibers traced from the ventral surface originated in the nucleus of the tractus solitarius and the dorsal nucleus of the vagus, both near the dorsal surfac...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(79)96054-3
更新日期：1979-05-01 00:00:00
abstract：:Serum choline concentrations decrease during and after surgery. We undertook this study to determine whether the decrease of choline is associated with an increase in stress hormones. In 16 patients undergoing abdominal surgery with general anesthesia, circulating choline cortisol, prolactin, adrenocorticotropic hormo...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(02)00171-4
更新日期：2002-05-10 00:00:00
abstract：:The left adrenal gland of the rat was perfused in vitro via the adrenal vein with Krebs-bicarbonate solution to study accumulation of exogenous catecholamines and secretion of endogenous norepinephrine and epinephrine by exposing the gland to various sympathomimetic agents. Perfusions with high concentrations of norep...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(84)90476-2
更新日期：1984-09-07 00:00:00
