Collagen gel and membrane in guided tissue regeneration in periodontal fenestration defects in dogs.

Abstract:

:The effect of a collagen gel matrix as a submembranous space-maintaining material was evaluated in guided tissue regeneration procedures. In 4 dogs, contralateral surgical circular fenestration defects, 5 mm in diameter, were produced at the midbuccal aspect of the alveolar bone in 8 maxillary canines. Removal of bone, PDL and cementum was complete. Experimental sites were filled with collagen gel and covered with collagen membranes; control sites were covered with collagen membranes and the underlying space was spontaneously filled with blood. Mucogingival flaps were repositioned. Histological and histomorphometric observations, 6 weeks post-surgery, indicated that defects covered by collagen membranes presented the most impressive regeneration with almost complete coverage of the denuded root by new cementum (98.4%) and new bone (63.2%). In the experimental defects, 83.5% coverage of new cementum with only 21.9% new bone regeneration was observed. These results suggest that collagen gel, interfered with healing by PDL and bone-derived cells in the submembranous space.

journal_name

J Clin Periodontol

authors

Tal H,Pitaru S,Moses O,Kozlovsky A

doi

10.1111/j.1600-051x.1996.tb00496.x

subject

Has Abstract

pub_date

1996-01-01 00:00:00

pages

1-6

issue

1

eissn

0303-6979

issn

1600-051X

journal_volume

23

pub_type

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