The association between missing teeth and non-alcoholic fatty liver disease in adults.

Abstract:

AIMS:Long-term oral chronic inflammatory process is closely related to systemic inflammation, which is a main mechanism involved in non-alcoholic fatty liver disease (NAFLD). Tooth loss could reflect the accumulation of oral local inflammation, implying that number of missing teeth may associate with NAFLD. This study evaluated the association between missing teeth and presence of NAFLD in a general population. MATERIALS AND METHODS:A cross-sectional study of 24,470 adults was carried out from the Tianjin Chronic Low-grade Systemic Inflammation and Health Cohort Study. The self-reported number of missing teeth (excluding third molars) was recorded and classified into four categories: 0, 1-2, 3-5, and ≥6. The NAFLD was diagnosed by the liver ultrasonography. Associations were analysed by adjusted multivariable logistic regression. RESULTS:The multivariable-adjusted odds ratios (95% confidence interval) of NAFLD across the categories of missing teeth were as follows: in males, 1.00 (reference), 1.04 (0.93-1.16), 1.06 (0.90-1.24), and 1.40 (1.09-1.81) (p for trend = 0.04); in females, 1.00 (reference), 0.98 (0.83-1.15), 1.11 (0.90-1.37), and 1.07 (0.77-1.48) (p for trend = 0.45). CONCLUSIONS:The number of missing teeth was associated with a higher presence of NAFLD in males but not females.

journal_name

J Clin Periodontol

authors

Qiao F,Fu K,Zhang Q,Liu L,Meng G,Wu H,Xia Y,Bao X,Gu Y,Shi H,Sun S,Wang X,Zhou M,Jia Q,Song K,Niu K

doi

10.1111/jcpe.12929

subject

Has Abstract

pub_date

2018-08-01 00:00:00

pages

941-951

issue

8

eissn

0303-6979

issn

1600-051X

journal_volume

45

pub_type

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