Collagen-mineral axial relationship in calcified turkey leg tendon by X-ray and neutron diffraction.


:The axial relationship between the collagen and mineral componetns in calcified turkey leg tendon was investigated using low-angle X-ray and neutron diffraction. The results indicate that the mineral is arranged with the same axial periodicity as the collagen and occupies the gap region of the collagen structure.






White SW,Hulmes DJ,Miller A,Timmins PA




Has Abstract


1977-03-31 00:00:00














  • Direct thermal neutron detection by the 2D semiconductor 6LiInP2Se6.

    abstract::Highly efficient neutron detectors are critical in many sectors, including national security1,2, medicine3, crystallography4 and astronomy5. The main neutron detection technologies currently used involve 3He-gas-filled proportional counters6 and light scintillators7 for thermalized neutrons. Semiconductors could provi...


    pub_type: 杂志文章


    authors: Chica DG,He Y,McCall KM,Chung DY,Pak RO,Trimarchi G,Liu Z,De Lurgio PM,Wessels BW,Kanatzidis MG

    更新日期:2020-01-01 00:00:00

  • Interpretation of the sonic hedgehog morphogen gradient by a temporal adaptation mechanism.

    abstract::Morphogens act in developing tissues to control the spatial arrangement of cellular differentiation. The activity of a morphogen has generally been viewed as a concentration-dependent response to a diffusible signal, but the duration of morphogen signalling can also affect cellular responses. One such example is the m...


    pub_type: 杂志文章


    authors: Dessaud E,Yang LL,Hill K,Cox B,Ulloa F,Ribeiro A,Mynett A,Novitch BG,Briscoe J

    更新日期:2007-11-29 00:00:00

  • Evidence that a free-running oscillator drives G1 events in the budding yeast cell cycle.

    abstract::In yeast and somatic cells, mechanisms ensure cell-cycle events are initiated only when preceding events have been completed. In contrast, interruption of specific cell-cycle processes in early embryonic cells of many organisms does not affect the timing of subsequent events, indicating that cell-cycle events are trig...


    pub_type: 杂志文章


    authors: Haase SB,Reed SI

    更新日期:1999-09-23 00:00:00

  • Direct control of shoot meristem activity by a cytokinin-activating enzyme.

    abstract::The growth of plants depends on continuous function of the meristems. Shoot meristems are responsible for all the post-embryonic aerial organs, such as leaves, stems and flowers. It has been assumed that the phytohormone cytokinin has a positive role in shoot meristem function. A severe reduction in the size of merist...


    pub_type: 杂志文章


    authors: Kurakawa T,Ueda N,Maekawa M,Kobayashi K,Kojima M,Nagato Y,Sakakibara H,Kyozuka J

    更新日期:2007-02-08 00:00:00

  • Publisher Correction: Viral and metazoan poxins are cGAMP-specific nucleases that restrict cGAS-STING signalling.

    abstract::In this Letter, Supplementary Fig. 1 was missing. This error has been corrected online. ...


    pub_type: 已发布勘误


    authors: Eaglesham JB,Pan Y,Kupper TS,Kranzusch PJ

    更新日期:2019-05-01 00:00:00

  • In vitro effects of high molecular weight forms of ACTH on the fetal sheep adrenal.

    abstract::The direct involvement of the pituitary-adrenal axis in birth has been well established, at least in sheep, and its removal prolongs pregnancy. As part of the process the fetal sheep adrenal grows rapidly during the 10-15 d prepartum and is associated with a large rise in the plasma corticosteroid concentration. This ...


    pub_type: 杂志文章


    authors: Roebuck MM,Jones CT,Holland D,Silman R

    更新日期:1980-04-17 00:00:00

  • Inhibition of histamine secretion from mast cells.

    abstract::Histamine secretion from mast cells may be inhibited by elevated intracellular levels of cyclic AMP and by several anti-allergic drugs. These compounds are claimed to act directly on the calcium-gating mechanism activated by the anaphylactic reaction, preventing influx of Ca2+ from the external environment and so bloc...


    pub_type: 杂志文章


    authors: Ennis M,Truneh A,White JR,Pearce FL

    更新日期:1981-01-15 00:00:00

  • Characterization and inhibition of a cholecystokinin-inactivating serine peptidase.

    abstract::A cholecystokinin (CCK)-inactivating peptidase was purified and identified as a membrane-bound isoform of tripeptidyl peptidase II (EC, a cytosolic subtilisin-like peptidase of previously unknown functions. The peptidase was found in neurons responding to cholecystokinin, as well as in non-neuronal cells. B...


    pub_type: 杂志文章


    authors: Rose C,Vargas F,Facchinetti P,Bourgeat P,Bambal RB,Bishop PB,Chan SM,Moore AN,Ganellin CR,Schwartz JC

    更新日期:1996-04-04 00:00:00

  • Enzymes trapped and zapped for use outside cells.

    abstract:: ...


    pub_type: 评论,新闻


    authors: Narayan A

    更新日期:2019-03-01 00:00:00

  • Mechanistic studies of an unprecedented enzyme-catalysed 1,2-phosphono-migration reaction.

    abstract::(S)-2-hydroxypropylphosphonate ((S)-2-HPP) epoxidase (HppE) is a mononuclear non-haem-iron-dependent enzyme responsible for the final step in the biosynthesis of the clinically useful antibiotic fosfomycin. Enzymes of this class typically catalyse oxygenation reactions that proceed via the formation of substrate radic...


    pub_type: 杂志文章


    authors: Chang WC,Dey M,Liu P,Mansoorabadi SO,Moon SJ,Zhao ZK,Drennan CL,Liu HW

    更新日期:2013-04-04 00:00:00

  • Thin-film thermoelectric devices with high room-temperature figures of merit.

    abstract::Thermoelectric materials are of interest for applications as heat pumps and power generators. The performance of thermoelectric devices is quantified by a figure of merit, ZT, where Z is a measure of a material's thermoelectric properties and T is the absolute temperature. A material with a figure of merit of around u...


    pub_type: 杂志文章


    authors: Venkatasubramanian R,Siivola E,Colpitts T,O'Quinn B

    更新日期:2001-10-11 00:00:00

  • DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected].

    abstract::Non-coding apurinic/apyrimidinic (AP) sites in DNA are continually created in cells both spontaneously and by damage-specific DNA glycosylases. The biologically critical human base excision repair enzyme APE1 cleaves the DNA sugar-phosphate backbone at a position 5' of AP sites to prime DNA repair synthesis. Here we r...


    pub_type: 杂志文章


    authors: Mol CD,Izumi T,Mitra S,Tainer JA

    更新日期:2000-01-27 00:00:00

  • Long-term sensitivity of soil carbon turnover to warming.

    abstract::The sensitivity of soil carbon to warming is a major uncertainty in projections of carbon dioxide concentration and climate. Experimental studies overwhelmingly indicate increased soil organic carbon (SOC) decomposition at higher temperatures, resulting in increased carbon dioxide emissions from soils. However, recent...


    pub_type: 杂志文章


    authors: Knorr W,Prentice IC,House JI,Holland EA

    更新日期:2005-01-20 00:00:00

  • Effects of modulators of myosin light-chain kinase activity in single smooth muscle cells.

    abstract::Phosphorylation of myosin light chains by a calmodulin-myosin light-chain kinase (MLCK) pathway is considered to be responsible for coupling increased calcium concentration with contraction in smooth muscle. This simple view has, however, recently been questioned. To test this hypothesis directly, we microinjected ind...


    pub_type: 杂志文章


    authors: Itoh T,Ikebe M,Kargacin GJ,Hartshorne DJ,Kemp BE,Fay FS

    更新日期:1989-03-09 00:00:00

  • The hydrodynamics of water strider locomotion.

    abstract::Water striders Gerridae are insects of characteristic length 1 cm and weight 10 dynes that reside on the surface of ponds, rivers, and the open ocean. Their weight is supported by the surface tension force generated by curvature of the free surface, and they propel themselves by driving their central pair of hydrophob...


    pub_type: 杂志文章


    authors: Hu DL,Chan B,Bush JW

    更新日期:2003-08-07 00:00:00

  • Evidence for kinks in DNA folding in the nucleosome.

    abstract::The nucleosome subunit of chromatin consists of DNA folded around a histone core as a 1.8-turn left-handed solenoid. The crystal structure of the nucleosome core particle revealed that it has a dyad symmetry axis and that the minor helix groove faces outwards from the protein core. Richmond et al. noticed that the pat...


    pub_type: 杂志文章


    authors: Hogan ME,Rooney TF,Austin RH

    更新日期:1987-08-06 00:00:00

  • Regulation of lifespan by sensory perception in Caenorhabditis elegans.

    abstract::Caenorhabditis elegans senses environmental signals through ciliated sensory neurons located primarily in sensory organs in the head and tail. Cilia function as sensory receptors, and mutants with defective sensory cilia have impaired sensory perception. Cilia are membrane-bound microtubule-based structures and in C. ...


    pub_type: 杂志文章


    authors: Apfeld J,Kenyon C

    更新日期:1999-12-16 00:00:00

  • Reconstitution in vitro of the entire cycle of the mouse female germ line.

    abstract::The female germ line undergoes a unique sequence of differentiation processes that confers totipotency to the egg. The reconstitution of these events in vitro using pluripotent stem cells is a key achievement in reproductive biology and regenerative medicine. Here we report successful reconstitution in vitro of the en...


    pub_type: 杂志文章


    authors: Hikabe O,Hamazaki N,Nagamatsu G,Obata Y,Hirao Y,Hamada N,Shimamoto S,Imamura T,Nakashima K,Saitou M,Hayashi K

    更新日期:2016-11-10 00:00:00

  • Extracellular domains mediating epsilon subunit interactions of muscle acetylcholine receptor.

    abstract::Ligand-gated ion channels, a major class of cell-surface proteins, have a pseudosymmetric structure with five highly homologous subunits arranged around a central ion pore. The correct assembly of each channel, whose subunit composition varies with cell type and stage of development, requires specific recognition betw...


    pub_type: 杂志文章


    authors: Yu XM,Hall ZW

    更新日期:1991-07-04 00:00:00

  • (Na/ + K+)ATPase has one functioning phosphorylation site per alpha subunit.

    abstract::(Na+ + K+)ATPase contains two different subunits, a catalytic subunit (alpha) and a subunit with uncertain function (beta). The enzyme binds ATP, ouabain and vanadate, and can be phosphorylated by ATP as well as by inorganic phosphate. From the previously reported maximal binding and phosphorylation capacities of 3.5-...


    pub_type: 杂志文章


    authors: Peters WH,Swarts HG,de Pont JJ,Schuurmans Stekhoven FM,Bonting SL

    更新日期:1981-03-26 00:00:00

  • Hypersensitive termination of the hypoxic response by a disordered protein switch.

    abstract::The cellular response to hypoxia is critical for cell survival and is fine-tuned to allow cells to recover from hypoxic stress and adapt to heterogeneous or fluctuating oxygen levels. The hypoxic response is mediated by the α-subunit of the transcription factor HIF-1 (HIF-1α), which interacts through its intrinsically...


    pub_type: 杂志文章


    authors: Berlow RB,Dyson HJ,Wright PE

    更新日期:2017-03-16 00:00:00

  • A general carbonyl alkylative amination for tertiary amine synthesis.

    abstract::The ubiquity of tertiary alkylamines in pharmaceutical and agrochemical agents, natural products and small-molecule biological probes1,2 has stimulated efforts towards their streamlined synthesis3-9. Arguably the most robust method for the synthesis of tertiary alkylamines is carbonyl reductive amination3, which compr...


    pub_type: 杂志文章


    authors: Kumar R,Flodén NJ,Whitehurst WG,Gaunt MJ

    更新日期:2020-05-01 00:00:00

  • Two types of dopamine neuron distinctly convey positive and negative motivational signals.

    abstract::Midbrain dopamine neurons are activated by reward or sensory stimuli predicting reward. These excitatory responses increase as the reward value increases. This response property has led to a hypothesis that dopamine neurons encode value-related signals and are inhibited by aversive events. Here we show that this is tr...


    pub_type: 杂志文章


    authors: Matsumoto M,Hikosaka O

    更新日期:2009-06-11 00:00:00

  • Formation of olfactory memories mediated by nitric oxide.

    abstract::Sheep learn to recognize the odours of their lambs within two hours of giving birth, and this learning involves synaptic changes within the olfactory bulb. Specifically, mitral cells become increasingly responsive to the learned odour, which stimulates release of both glutamate and GABA (gamma-aminobutyric acid) neuro...


    pub_type: 杂志文章


    authors: Kendrick KM,Guevara-Guzman R,Zorrilla J,Hinton MR,Broad KD,Mimmack M,Ohkura S

    更新日期:1997-08-14 00:00:00

  • Neural circuitry linking mating and egg laying in Drosophila females.

    abstract::Mating and egg laying are tightly cooordinated events in the reproductive life of all oviparous females. Oviposition is typically rare in virgin females but is initiated after copulation. Here we identify the neural circuitry that links egg laying to mating status in Drosophila melanogaster. Activation of female-speci...


    pub_type: 杂志文章


    authors: Wang F,Wang K,Forknall N,Patrick C,Yang T,Parekh R,Bock D,Dickson BJ

    更新日期:2020-03-01 00:00:00

  • A brood parasitic catfish of mouthbrooding cichlid fishes in Lake Tanganyika.

    abstract::Brood parasitism, where a brood of the parasitic species is fostered by the parents of another species, is well known among birds. In most cases, such offspring show a complete reliance upon their host parents for food, protection and warmth until their independence. In other vertebrate groups, however, such total dep...


    pub_type: 杂志文章


    authors: Sato T

    更新日期:1986-09-04 00:00:00

  • Use of chlorotetracycline fluorescence to demonstrate Ca2+-induced release of Ca2+ from the sarcoplasmic reticulum of skinned cardiac cells.

    abstract::It has been proposed that the trans-sarcolemmal influx of Ca2+ occurring during the plateau of the mammalian cardiac action potentials is insufficient in itself to activate the myofilaments, but can trigger a release of Ca2+ from the sarcoplasmic reticulum (SR) which is sufficient for activation. The demonstration of ...


    pub_type: 杂志文章


    authors: Fabiato A,Fabiato F

    更新日期:1979-09-13 00:00:00

  • SWI6 protein is required for transcription of the periodically expressed DNA synthesis genes in budding yeast.

    abstract::In budding yeast many genes are expressed under cell-cycle control in late G1. These include a large group of DNA synthesis genes, the HO gene involved in mating-type switching, CTS1 (chitinase) and also CLN1 and CLN2 (ref. 4) encoding G1 cyclins. Two factors, encoded by the SWI4 and SWI6 genes, are required for HO (r...


    pub_type: 杂志文章


    authors: Lowndes NF,Johnson AL,Breeden L,Johnston LH

    更新日期:1992-06-11 00:00:00

  • Travel at low energetic cost by swimming and wave-riding bottlenose dolphins.

    abstract::Over the past 50 years there has been much speculation about the energetic cost of swimming and wave-riding by dolphins. When aligned properly in front of the bow of moving ships in the stern wake of small boats, on wind waves, and even in the wake of larger cetaceans, the animals appear to move effortlessly through t...


    pub_type: 杂志文章


    authors: Williams TM,Friedl WA,Fong ML,Yamada RM,Sedivy P,Haun JE

    更新日期:1992-02-27 00:00:00

  • Hydrogen peroxide sensor HPCA1 is an LRR receptor kinase in Arabidopsis.

    abstract::Hydrogen peroxide (H2O2) is a major reactive oxygen species in unicellular and multicellular organisms, and is produced extracellularly in response to external stresses and internal cues1-4. H2O2 enters cells through aquaporin membrane proteins and covalently modifies cytoplasmic proteins to regulate signalling and ce...


    pub_type: 杂志文章


    authors: Wu F,Chi Y,Jiang Z,Xu Y,Xie L,Huang F,Wan D,Ni J,Yuan F,Wu X,Zhang Y,Wang L,Ye R,Byeon B,Wang W,Zhang S,Sima M,Chen S,Zhu M,Pei J,Johnson DM,Zhu S,Cao X,Pei C,Zai Z,Liu Y,Liu T,Swift GB,Zhang W,Y

    更新日期:2020-02-01 00:00:00