DNA fingerprinting dispute laid to rest.

abstract：:Continental rifts are important sources of mantle carbon dioxide (CO2) emission into Earth's atmosphere1-3. Because deep carbon is stored for long periods in the lithospheric mantle4-6, rift CO2 flux depends on lithospheric processes that control melt and volatile transport1,3,7. The influence of compositional and thi...

journal_title：Nature

authors： Muirhead JD,Fischer TP,Oliva SJ,Laizer A,van Wijk J,Currie CA,Lee H,Judd EJ,Kazimoto E,Sano Y,Takahata N,Tiberi C,Foley SF,Dufek J,Reiss MC,Ebinger CJ

更新日期：2020-06-01 00:00:00

abstract：:Retinoic acid may be the natural morphogen used to generate digit pattern in the chick limb bud. It has been proposed that retinoic acid acts by binding to a cellular retinoic acid-binding protein (CRABP) and then entering the nucleus to alter the pattern of gene activity. High-affinity receptors that bind both retino...

journal_title：Nature

authors： Maden M,Ong DE,Summerbell D,Chytil F

更新日期：1988-10-20 00:00:00

abstract：:Phosphorylation of myosin light chains by a calmodulin-myosin light-chain kinase (MLCK) pathway is considered to be responsible for coupling increased calcium concentration with contraction in smooth muscle. This simple view has, however, recently been questioned. To test this hypothesis directly, we microinjected ind...

journal_title：Nature

authors： Itoh T,Ikebe M,Kargacin GJ,Hartshorne DJ,Kemp BE,Fay FS

更新日期：1989-03-09 00:00:00

abstract：:C-type (Ca(2+)-dependent) animal lectins such as mannose-binding proteins mediate many cell-surface carbohydrate-recognition events. The crystal structure at 1.7 A resolution of the carbohydrate-recognition domain of rat mannose-binding protein complexed with an oligomannose asparaginyl-oligosaccharide reveals that Ca...

journal_title：Nature

authors： Weis WI,Drickamer K,Hendrickson WA

更新日期：1992-11-12 00:00:00

abstract：:Regulatory T cells (Treg cells), a distinct subset of CD4+ T cells, are necessary for the maintenance of immune self-tolerance and homeostasis1,2. Recent studies have demonstrated that Treg cells exhibit a unique metabolic profile, characterized by an increase in mitochondrial metabolism relative to other CD4+ effecto...

journal_title：Nature

authors： Weinberg SE,Singer BD,Steinert EM,Martinez CA,Mehta MM,Martínez-Reyes I,Gao P,Helmin KA,Abdala-Valencia H,Sena LA,Schumacker PT,Turka LA,Chandel NS

更新日期：2019-01-01 00:00:00

abstract：:Interchromosomal gene conversion between alleles has been shown in yeast frequently to be associated with the recombination of flanking genetic markers. Although this also holds true for gene conversion between two alleles of the yeast mating-type (MAT) locus, initiated by the homothallic switching system, we find no ...

journal_title：Nature

authors： Klar AJ,Strathern JN

更新日期：1984-08-30 00:00:00

abstract：:Particle acceleration based on high intensity laser systems (a process known as laser-plasma acceleration) has achieved high quality particle beams that compare favourably with conventional acceleration techniques in terms of emittance, brightness and pulse duration. A long-term difficulty associated with laser-plasma...

journal_title：Nature

authors： Schwoerer H,Pfotenhauer S,Jäckel O,Amthor KU,Liesfeld B,Ziegler W,Sauerbrey R,Ledingham KW,Esirkepov T

更新日期：2006-01-26 00:00:00

abstract：:Obesity is a disorder of energy balance, indicating a chronic disequilibrium between energy intake and expenditure. Recently, the mouse ob gene, and subsequently its human and rat homologues, have been cloned. The ob gene product, leptin, is expressed exclusively in adipose tissue, and appears to be a signalling facto...

journal_title：Nature

authors： Saladin R,De Vos P,Guerre-Millo M,Leturque A,Girard J,Staels B,Auwerx J

更新日期：1995-10-12 00:00:00

abstract：:In lung diseases such as asthma, expiratory flow becomes limited, airways can collapse and the vital exchange of gases is compromised. Here we model the inflation of collapsed regions of the lung during inspiration in terms of avalanches propagating through a bifurcating network of airways, and find that the accompany...

journal_title：Nature

authors： Alencar AM,Arold SP,Buldyrev SV,Majumdar A,Stamenović D,Stanley HE,Suki B

更新日期：2002-06-20 00:00:00

abstract：:Recognition of sweet, bitter and umami tastes requires the non-vesicular release from taste bud cells of ATP, which acts as a neurotransmitter to activate afferent neural gustatory pathways. However, how ATP is released to fulfil this function is not fully understood. Here we show that calcium homeostasis modulator 1 ...

journal_title：Nature

authors： Taruno A,Vingtdeux V,Ohmoto M,Ma Z,Dvoryanchikov G,Li A,Adrien L,Zhao H,Leung S,Abernethy M,Koppel J,Davies P,Civan MM,Chaudhari N,Matsumoto I,Hellekant G,Tordoff MG,Marambaud P,Foskett JK

更新日期：2013-03-14 00:00:00

abstract：:Bacterial adhesion pili are designed to bind specifically and maintain attachment of bacteria to target cells. Uropathogenic P-pili are sufficiently mechanically resilient to resist the cleansing action of urine flow that removes most other bacteria. P-pili are 68 A in diameter and approximately 1 micron long, and are...

journal_title：Nature

authors： Bullitt E,Makowski L

更新日期：1995-01-12 00:00:00

abstract：:Poly(dA).poly(dT) has unusual properties in that it cannot associate into nucleosomes and short, phased runs of it cause DNA bending. The crystal structure of a B-type DNA dodecamer containing a homopolymeric run of six A.T base pairs shows that this region possesses special structural features, including a system of ...

journal_title：Nature

authors： Nelson HC,Finch JT,Luisi BF,Klug A

更新日期：1987-11-19 00:00:00

abstract：:More than twenty types of retinal ganglion cells conduct visual information from the eye to the rest of the brain. Each retinal ganglion cell type tessellates the retina in a regular mosaic, so that every point in visual space is processed for visual primitives such as contrast and motion. This information flows to tw...

journal_title：Nature

authors： Feinberg EH,Meister M

更新日期：2015-03-12 00:00:00

abstract：:In standard fluid dynamics, the density change associated with flow is often assumed to be negligible, implying that the fluid is incompressible. For example, this has been established for simple shear flows, where no pressure change is associated with flow: there is no volume deformation due to viscous stress and ine...

journal_title：Nature

authors： Furukawa A,Tanaka H

更新日期：2006-09-28 00:00:00

abstract：:A review of fossil mammalian faunas from the Middle Awash indicates they span most of the later Neogene and document evolutionary change in several mammalian groups, especially Primates, Proboscidea and Artiodactyla. Oldowan artefacts first appear in the late Pliocene, while Acheulian and later industries and apparent...

journal_title：Nature

authors： Kalb JE,Jolly CJ,Mebrate A,Tebedge S,Smart C,Oswald EB,Cramer D,Whitehead P,Wood CB,Conroy GC,Adefris T,Sperling L,Kana B

更新日期：1982-07-01 00:00:00

abstract：:In the Northern Hemisphere, ozone levels in the troposphere have increased by 35 per cent over the past century, with detrimental impacts on forest and agricultural productivity, even when forest productivity has been stimulated by increased carbon dioxide levels. In addition to reducing productivity, increased tropos...

journal_title：Nature

authors： Loya WM,Pregitzer KS,Karberg NJ,King JS,Giardina CP

更新日期：2003-10-16 00:00:00

abstract：:Exploiters (parasites and predators) are thought to play a significant role in diversification, and ultimately speciation, of their hosts or prey. Exploiters may drive sympatric (within-population) diversification if there are a variety of exploiter-resistance strategies or fitness costs associated with exploiter resi...

journal_title：Nature

authors： Buckling A,Rainey PB

更新日期：2002-12-05 00:00:00

abstract：:Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis largely owing to inefficient diagnosis and tenacious drug resistance. Activation of pancreatic stellate cells (PSCs) and consequent development of dense stroma are prominent features accounting for this aggressive biology1,2. The reciprocal interplay betwe...

journal_title：Nature

authors： Shi Y,Gao W,Lytle NK,Huang P,Yuan X,Dann AM,Ridinger-Saison M,DelGiorno KE,Antal CE,Liang G,Atkins AR,Erikson G,Sun H,Meisenhelder J,Terenziani E,Woo G,Fang L,Santisakultarm TP,Manor U,Xu R,Becerra CR,Borazanci

更新日期：2019-05-01 00:00:00

abstract：:Growing populations and agricultural intensification have led to raised riverine nitrogen (N) loads, widespread oxygen depletion in coastal zones (coastal hypoxia)1 and increases in the incidence of algal blooms.Although recent work has suggested that individual wetlands have the potential to improve water quality2-9,...

journal_title：Nature

authors： Cheng FY,Van Meter KJ,Byrnes DK,Basu NB

更新日期：2020-12-01 00:00:00

abstract：:The lack of a reliable theory of glass physics has led to the pursuit of correlations between various glass or viscous liquid parameters, one of which is the slope m of the plot of log(viscosity) against Tg/T, extrapolated at the glass-transition temperature, Tg, also termed 'fragility'. Novikov and Sokolov conclude t...

journal_title：Nature

authors： Yannopoulos SN,Johari GP

更新日期：2006-08-03 00:00:00

abstract：:Modern chitons (Mollusca: Polyplacophora) possess a highly conserved skeleton of eight shell plates (valves) surrounded by spicules or scales, and fossil evidence suggests that the chiton skeleton has changed little since the first appearance of the class in the Late Cambrian period (about 500 million years before pre...

journal_title：Nature

authors： Vendrasco MJ,Wood TE,Runnegar BN

更新日期：2004-05-20 00:00:00

abstract：:Humans and other animals must often make decisions on the basis of imperfect evidence. Statisticians use measures such as P values to assign degrees of confidence to propositions, but little is known about how the brain computes confidence estimates about decisions. We explored this issue using behavioural analysis an...

journal_title：Nature

authors： Kepecs A,Uchida N,Zariwala HA,Mainen ZF

更新日期：2008-09-11 00:00:00

abstract：:Unicellular organisms such as yeasts require a single cyclin-dependent kinase, Cdk1, to drive cell division. In contrast, mammalian cells are thought to require the sequential activation of at least four different cyclin-dependent kinases, Cdk2, Cdk3, Cdk4 and Cdk6, to drive cells through interphase, as well as Cdk1 t...

journal_title：Nature

authors： Santamaría D,Barrière C,Cerqueira A,Hunt S,Tardy C,Newton K,Cáceres JF,Dubus P,Malumbres M,Barbacid M

更新日期：2007-08-16 00:00:00

abstract：:Control of protein synthesis is associated with changes in the ratio of intracellular Na+ to K+ in the cultured embryonic chick lens. Correlations of intracellular Na+/K+ ratios with crystallin synthesis and cataract formation in vitro suggest that the Na+/K+ ratio may have an important role in the regulation of prote...

journal_title：Nature

authors： Shinohara T,Piatigorsky J

更新日期：1977-12-01 00:00:00

abstract：:In mice, the Ter mutation causes primordial germ cell (PGC) loss in all genetic backgrounds. Ter is also a potent modifier of spontaneous testicular germ cell tumour (TGCT) susceptibility in the 129 family of inbred strains, and markedly increases TGCT incidence in 129-Ter/Ter males. In 129-Ter/Ter mice, some of the r...

journal_title：Nature

authors： Youngren KK,Coveney D,Peng X,Bhattacharya C,Schmidt LS,Nickerson ML,Lamb BT,Deng JM,Behringer RR,Capel B,Rubin EM,Nadeau JH,Matin A

更新日期：2005-05-19 00:00:00

abstract：:Dominant alleles at the agouti locus (A) cause an obesity syndrome in the mouse, as a consequence of ectopic expression of the agouti peptide. This peptide, normally only found in the skin, is a high-affinity antagonist of the melanocyte-stimulating hormone receptor (MC1-R), thus explaining the inhibitory effect of ag...

journal_title：Nature

authors： Fan W,Boston BA,Kesterson RA,Hruby VJ,Cone RD

更新日期：1997-01-09 00:00:00

abstract：:The generation of strong serological responses to protein antigens in experimental animals usually requires the use of potent adjuvants, most of which cannot be used in human or veterinary vaccines because of deleterious side effects. Attempting to circumvent this problem, we have assessed an adjuvant-free antigen-del...

journal_title：Nature

authors： Carayanniotis G,Barber BH

更新日期：1987-05-07 00:00:00

abstract：:Generalization is a cognitive ability that allows similar stimuli along a given dimension to be treated as equivalents. Insects exhibit high levels of visual generalization. Honeybees trained to recognize complex visual stimuli on the basis of a single feature generalize their choice to novel stimuli sharing that comm...

journal_title：Nature

authors： Stach S,Benard J,Giurfa M

更新日期：2004-06-17 00:00:00

abstract：:With the discovery1 of superconductivity at 203 kelvin in H3S, attention returned to conventional superconductors with properties that can be described by the Bardeen-Cooper-Schrieffer and the Migdal-Eliashberg theories. Although these theories predict the possibility of room-temperature superconductivity in metals th...

journal_title：Nature

authors： Drozdov AP,Kong PP,Minkov VS,Besedin SP,Kuzovnikov MA,Mozaffari S,Balicas L,Balakirev FF,Graf DE,Prakapenka VB,Greenberg E,Knyazev DA,Tkacz M,Eremets MI

更新日期：2019-05-01 00:00:00

abstract：:Crohn's disease is a debilitating inflammatory bowel disease (IBD) that can involve the entire digestive tract. A single-nucleotide polymorphism (SNP) encoding a missense variant in the autophagy gene ATG16L1 (rs2241880, Thr300Ala) is strongly associated with the incidence of Crohn's disease. Numerous studies have dem...

journal_title：Nature

authors： Murthy A,Li Y,Peng I,Reichelt M,Katakam AK,Noubade R,Roose-Girma M,DeVoss J,Diehl L,Graham RR,van Lookeren Campagne M

更新日期：2014-02-27 00:00:00