Prostaglandins and diabetic nephropathy.

abstract：OBJECTIVE:Type 2 diabetes mellitus (DM-2) is an important cardiovascular risk factor, although hardly any data are available in our country. Therefore, we decided to study the incidence of cardiovascular disease (CVD) and the related variables with its appearance in a group of patients with DM-2. RESEARCH DESIGN AND M...

journal_title：Journal of diabetes and its complications

authors： Rius Riu F,Salinas Vert I,Lucas Martín A,Romero González R,Sanmartí Sala A

更新日期：2003-09-01 00:00:00

abstract：:The mechanism(s) resulting in the premature atherosclerosis of diabetes is unknown. Increased phagocyte release of reactive oxygen species such as superoxide anion (O2.-), resulting in low-density lipoprotein (LDL) oxidation, could be one possible cause. The purpose of the present study was to compare the abilities of...

journal_title：Journal of diabetes and its complications

authors： Fuller CJ,Agil A,Lender D,Jialal I

更新日期：1996-07-01 00:00:00

abstract：:The aim of our study was to compare ambulatory blood pressure monitoring (ABPM) measures (mean systolic/diastolic blood pressure, diurnal rhythm, and pressure burden) in matched normo- and microalbuminuric (IDDM) adolescents and healthy controls. Twenty-four hour monitoring was undertaken in 39 normotensive (normal cl...

journal_title：Journal of diabetes and its complications

authors： Sochett EB,Poon I,Balfe W,Daneman D

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVE:Type 1 diabetes (T1DM) is a pro-inflammatory state characterized by high C-reactive protein (CRP) levels. However, there is a paucity of data examining the role of CRP in promoting the pro-inflammatory state of diabetes. Thus, we examined the pro-inflammatory effects of human CRP using spontaneously diabetic ...

journal_title：Journal of diabetes and its complications

authors： Jialal I,Kaur H,Devaraj S

更新日期：2013-01-01 00:00:00

abstract：:There is increasing evidence that glycemic disorders such as rapid glucose fluctuations over a daily period might play an important role on diabetic complications. We evaluated the efficacy of sitagliptin 100 mg once daily vs. vildagliptin 50 mg twice daily on daily blood glucose fluctuations in patients with type 2 d...

journal_title：Journal of diabetes and its complications

authors： Marfella R,Barbieri M,Grella R,Rizzo MR,Nicoletti GF,Paolisso G

更新日期：2010-03-01 00:00:00

abstract：AIMS:To analyze the seasonal variations in A1c levels among a southern European diabetic population. METHODS:We examined all monthly-grouped A1c determinations from diabetic patients during the period 2006-2011, in a region of southern Spain. RESULTS:There were 61,329 records available. The mean A1c value was 56mmol/...

journal_title：Journal of diabetes and its complications

authors： Gomez-Huelgas R,Santamaria-Fernandez S,Guijarro-Merino R,Navajas-Luque F,Tinahones FJ,Roman-Teran CM,Picon MJ,Bernal-Lopez MR

更新日期：2013-11-01 00:00:00

abstract：AIMS:Compare performances of diabetes risk scores and glycated hemoglobin (HbA1c) to estimate the risk of incident type 2 diabetes mellitus (T2DM) in Northeast Germany. METHODS:We studied 2916 subjects (20 to 81years) from the Study of Health in Pomerania (SHIP) in a 5-year follow-up period. Diabetes risk scores inclu...

journal_title：Journal of diabetes and its complications

authors： Krabbe CEM,Schipf S,Ittermann T,Dörr M,Nauck M,Chenot JF,Markus MRP,Völzke H

更新日期：2017-11-01 00:00:00

abstract：:Although slow gastric emptying (gastroparesis) is a well-known complication of chronic hyperglycemia in diabetes mellitus (DM), it recently has become clear that rapid gastric emptying also is a frequent and important diabetic complication. In contrast, acute hyperglycemia causes slow gastric emptying, and acute hypog...

journal_title：Journal of diabetes and its complications

authors： Goyal RK,Cristofaro V,Sullivan MP

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:In this study we evaluated the association of baseline levels of six different candidate proteins for the development of microalbuminuria and macroalbuminuria in type 1 diabetic patients, who were followed for approximately 30 years. Two of the proteins are markers of inflammation: serum amyloid A (SAA) and ...

journal_title：Journal of diabetes and its complications

authors： Overgaard AJ,McGuire JN,Hovind P,Parving HH,Rossing P,Pociot F

更新日期：2013-01-01 00:00:00

abstract：AIMS:To investigate the effect of a single nucleotide polymorphism (SNP) in transmembrane protein 182 (TMEM182) on the risk of having central obesity and the related phenotype. METHODS:In total, 2141 subjects with central obesity (n = 827) and normal controls (n = 1314) were included. The most strongly associated SNPs...

journal_title：Journal of diabetes and its complications

authors： Ma M,Lee JH,Kim M

更新日期：2020-12-01 00:00:00

abstract：:This work presents a systematic review of long-term risk assessment models for evaluating the probability of developing complications in diabetes patients. Diabetes mellitus can cause many complications if not adequately controlled; risk assessment models can help physicians and patients in identifying the complicatio...

journal_title：Journal of diabetes and its complications

authors： Lagani V,Koumakis L,Chiarugi F,Lakasing E,Tsamardinos I

更新日期：2013-07-01 00:00:00

abstract：AIMS:To investigate serum beta2-glycoprotein I-low-density lipoprotein (β2-GPI-LDL) and oxidized low-density lipoprotein (ox-LDL) levels in type 2 diabetes mellitus (T2DM) patients, and to further evaluate the associations of β2-GPI-LDL with ox-LDL in vivo and with the presence of diabetic microvascular complications. ...

journal_title：Journal of diabetes and its complications

authors： Yu R,Yuan Y,Niu D,Song J,Liu T,Wu J,Wang J

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:There are significant regional variations in prevalence of diabetes and diabetic chronic renal insufficiency (CRI) in India. Oxidative stress plays an important role in the development of diabetic complications. To determine the importance of the polymorphisms in the genes involved in maintenance of cellular...

journal_title：Journal of diabetes and its complications

authors： Tiwari AK,Prasad P,B K T,Kumar KM,Ammini AC,Gupta A,Gupta R

更新日期：2009-03-01 00:00:00

abstract：:A 27-year-old male, who had developed diabetes mellitus type 1 (DMT1) since the age of eighteen and alopecia areata universalis nine months later, attended the outpatient clinics complaining of general fatigue and shortness of breath. A Schilling test was indicative of pernicious anemia. Antigastric parietal cell (AGP...

journal_title：Journal of diabetes and its complications

authors： Tzellos TG,Tahmatzidis DK,Lallas A,Apostolidou K,Goulis DG

更新日期：2009-11-01 00:00:00

abstract：AIMS:To develop and validate prediction equations to identify individuals at high risk for type 2 diabetes using existing health plan data. METHODS:Health plan data from 2005 to 2009 from 18,527 members of a Midwestern HMO without diabetes, 6% of whom had fasting plasma glucose (FPG) ≥110mg/dL, and health plan data fr...

journal_title：Journal of diabetes and its complications

authors： McEwen LN,Adams SR,Schmittdiel JA,Ferrara A,Selby JV,Herman WH

更新日期：2013-11-01 00:00:00

abstract：:The aim of this cross-sectional study was to determine the significant limitations, sensitivity, specificity, partial correlations, and odds ratios of nutrient intake in patients with and without hypertension with Type 2 diabetes mellitus. Diabetic patients (n=220) with clinical diagnosis of hypertension and diabetic ...

journal_title：Journal of diabetes and its complications

authors： Celik F,Celik M,Akpolat V

更新日期：2009-09-01 00:00:00

abstract：STATEMENT OF THE PROBLEM:Medial arterial calcinosis (MAC) is associated with neuropathy, amputation, and mortality through an unknown mechanism. We hypothesized that MAC was a marker of autonomic neuropathy rather than a risk factor and that the outcomes were due to autonomic neuropathy. METHODS:All subjects in an ong...

journal_title：Journal of diabetes and its complications

authors： Mayfield JA,Caps MT,Boyko EJ,Ahroni JH,Smith DG

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Altered platelet morphology and function have been reported in patients with diabetes mellitus. They are likely to be associated with the pathological processes and increased risk of vascular disease seen in these patients. We aimed to determine the mean platelet volume (MPV) in diabetics compared to nondiab...

journal_title：Journal of diabetes and its complications

authors： Hekimsoy Z,Payzin B,Ornek T,Kandoğan G

更新日期：2004-05-01 00:00:00

abstract：:Monocyte chemoattractant protein-1 (MCP-1), is a chemokine that mediates renal interstitial inflammation, tubular atrophy, and interstitial fibrosis by recruiting monocytes/macrophages into renal tubulointerstitium. Recent studies have demonstrated that protein overload in renal tubular cells up-regulates MCP-1 gene a...

journal_title：Journal of diabetes and its complications

authors： Morii T,Fujita H,Narita T,Shimotomai T,Fujishima H,Yoshioka N,Imai H,Kakei M,Ito S

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:The notion of combining immunomodulatory agents with the incretin exendin-4 (Ex-4) has seen considerable favor as a potential therapy for the reversal of type 1 diabetes in man. While the addition of Ex-4 provides modest improvement to the effectiveness of immunological-based monotherapies in reversing hyperg...

journal_title：Journal of diabetes and its complications

authors： Xue S,Wasserfall C,Parker M,McGrail S,McGrail K,Campbell-Thompson M,Schatz DA,Atkinson MA,Haller MJ

更新日期：2010-05-01 00:00:00

abstract：:This study was designed to determine the incidence and prevalence of amputations in diabetic Mexican American elders and to identify correlates of lower extremity amputations. Data for this study came from baseline and two follow-up interviews of the Hispanic Established Population for the Epidemiological Study of the...

journal_title：Journal of diabetes and its complications

authors： Otiniano ME,Du X,Ottenbacher K,Black SA,Markides KS

更新日期：2003-03-01 00:00:00

abstract：:The aim was to evaluate the relative importance of an established battery of five function tests used in the assessment of cardiovascular autonomic neuropathy (CAN) in diabetes employing spectral analysis of heart rate variability (HRV) as the reference test. In a population-based sample of 178 diabetic persons and 19...

journal_title：Journal of diabetes and its complications

authors： May O,Arildsen H

更新日期：2000-01-01 00:00:00

abstract：AIMS:The aim of this study was to investigate the association between Type 2 diabetes and community-acquired infections. METHODS:We recruited 68 patients (mean+/-S.D. age=64.9+/-9.1 years; 57.4% males) from a community-based cohort and their nondiabetic partners (age=63.8+/-9.9 years; mean relationship duration=37.3+/...

journal_title：Journal of diabetes and its complications

authors： Davis TM,Weerarathne T,Foong Y,Mason C,Davis WA

更新日期：2005-09-01 00:00:00

abstract：:A few reports have suggested that angiotensin-converting enzyme inhibitors (ACE-I) have a beneficial effect on mild diabetic retinopathy (DR). This pilot study was carried out to determine if a small dose of an ACE-I would retard the progression of moderate to severe DR in normotensive Type 2 diabetic patients. Normot...

journal_title：Journal of diabetes and its complications

authors： Pradhan R,Fong D,March C,Jack R,Rezapour G,Norris K,Davidson MB

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Evidence indicates an early neural injury of the retinal cells in diabetes. The aim of the current study was to investigate the apoptosis of the retinal cells and the relationship with CGRP. MATERIALS AND METHODS:The diabetes was induced by treatment of STZ, using which the apoptosis of retinal cells, the c...

journal_title：Journal of diabetes and its complications

authors： Yang JH,Guo Z,Zhang T,Meng XX,Sun T,Wu J

更新日期：2013-11-01 00:00:00

abstract：:Hyperglycemic syndromes cause disturbances in the tonicity of body fluids, the distribution of body water between major body fluid compartments, and the external balance of body solute and water. The unique feature of dialysis-associated hyperglycemia (DH) is that, during its development, it can cause changes exclusiv...

journal_title：Journal of diabetes and its complications

authors： Tzamaloukas AH,Ing TS,Siamopoulos KC,Rohrscheib M,Elisaf MS,Raj DS,Murata GH

更新日期：2007-11-01 00:00:00

abstract：AIMS:Discrimination is linked to negative health outcomes, but little research has investigated how the cumulative effect of discrimination impacts perceptions of care. This study investigated the influence of cumulative perceived discrimination on quality of care, patient-centeredness, and dissatisfaction with care in...

journal_title：Journal of diabetes and its complications

authors： Cykert DM,Williams JS,Walker RJ,Davis KS,Egede LE

更新日期：2017-01-01 00:00:00

abstract：AIMS:The aim of this study is to explore whether administration timing affects glycaemic control by lixisenatide once-daily in type 2 diabetes mellitus (T2DM). METHODS:A phase IIIb, open-label, 1:1 randomized, active-controlled, 24-week multicentre study of T2DM patients inadequately controlled on metformin was conduc...

journal_title：Journal of diabetes and its complications

authors： Ahrén B,Vorokhobina N,Souhami E,Demil N,Ye J,Aronson R

更新日期：2014-09-01 00:00:00

abstract：AIMS:We hypothesized that Hispanic/Latino youth at high risk for diabetes would have elevated biomarkers of endothelial dysfunction. METHODS:Among 1316 children 8-16years old from the Study of Latino Youth (SOL Youth), we used Poisson regression to obtain prevalence ratios (PRs) and 95% CIs for the cross-sectional ass...

journal_title：Journal of diabetes and its complications

authors： Parrinello CM,Hua S,Carnethon MR,Gallo LC,Hudson BI,Goldberg RB,Delamater AM,Kaplan RC,Isasi CR

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Digital toe amputation is a relatively minor surgical procedure but there is a historical view that it is the "first stage in a predictable clinical course" leading to eventual limb loss. There is a paucity of contemporaneous data on the long-term outcomes of patients undergoing toe amputation. We aim to stu...

journal_title：Journal of diabetes and its complications

authors： Griffin KJ,Rashid TS,Bailey MA,Bird SA,Bridge K,Scott JD

更新日期：2012-05-01 00:00:00