Ambulatory blood pressure monitoring in insulin-dependent diabetes mellitus adolescents with and without microalbuminuria.

Abstract:

:The aim of our study was to compare ambulatory blood pressure monitoring (ABPM) measures (mean systolic/diastolic blood pressure, diurnal rhythm, and pressure burden) in matched normo- and microalbuminuric (IDDM) adolescents and healthy controls. Twenty-four hour monitoring was undertaken in 39 normotensive (normal clinic blood pressure measurements) IDDM adolescents (22 normo- and 17 microalbuminuric subjects) and 23 controls. Subjects were matched for age, bodymass index, gender, and IDDM duration. Microalbuminuria was diagnosed on the basis of a urinary albumin excretion rate greater than 15 but less than 200 micrograms/min in two of the three 24-h urine collections. The microalbuminuric patients differed from the normoalbuminuric subjects and controls in having higher mean 24-h and overnight systolic pressure, loss of systolic diurnal rhythm and increased systolic and diastolic pressure burden. There were no differences between the three groups in diastolic blood pressure. The normoalbuminuric group differed from the controls only with respect to an increased systolic pressure burden. Microalbuminuric IDDM adolescents show similar, albeit milder changes in ABPM, to those reported in adults with microalbuminuria. We postulate that these milder changes represent an earlier phase to that observed in the adult population and that taken together, the adolescent and adult data suggests a specific order in the development of ABPM changes in diabetic subjects.

authors

Sochett EB,Poon I,Balfe W,Daneman D

doi

10.1016/s1056-8727(97)00050-0

subject

Has Abstract

pub_date

1998-01-01 00:00:00

pages

18-23

issue

1

eissn

1056-8727

issn

1873-460X

pii

S1056-8727(97)00050-0

journal_volume

12

pub_type

杂志文章
  • Metformin prevents glucotoxicity by alleviating oxidative and ER stress-induced CD36 expression in pancreatic beta cells.

    abstract:AIM/HYPOTHESIS:Cluster determinant 36 (CD36), a fatty acid transporter, was reported to have a pivotal role in glucotoxicity-induced beta cell dysfunction. However, little is known about how glucotoxicity influences CD36 expression, and it is unknown whether this action can be counteracted by metformin. In the present ...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2016.09.001

    authors: Moon JS,Karunakaran U,Elumalai S,Lee IK,Lee HW,Kim YW,Won KC

    更新日期:2017-01-01 00:00:00

  • Awareness of hypoglycemia and spectral analysis of heart rate variability in type 1 diabetes.

    abstract:AIMS:To investigate the relationship of unawareness of hypoglycemia with spectral analysis of heart rate variability (HRV) and clinical variables in type 1 diabetes (T1D) individuals. METHODS:Participants with type 1 diabetes mellitus (type 1 diabetes) were prospectively assessed for hypoglycemia awareness using the P...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2020.107617

    authors: Paes T,Rolim LC,Filho CS,de Sa JR,Dib SA

    更新日期:2020-08-01 00:00:00

  • Mexican population sub-analysis of the lixilan clinical program with the fixed ratio combination of insulin glargine and lixisenatide (iGlarLixi).

    abstract:AIM:To evaluate the efficacy and safety of iGlarLixi in Mexican patients with type 2 diabetes who participated in the LixiLan clinical trials and compare results with the rest of the patients. METHODS:Data was collected for Mexican patients who participated in either of three studies: phase 2 trial LixiLan-POC, that c...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2019.05.020

    authors: González-Gálvez G,Díaz-Toscano ML,Llamas-Moreno JF,Fernández-Rodarte K,Sañudo-Maury ME

    更新日期:2020-08-01 00:00:00

  • Risk factors for autonomic and somatic nerve dysfunction in different stages of glucose tolerance.

    abstract:AIM:The present study evaluates autonomic and somatic nerve function in different stages of glucose tolerance and its correlation with different cardio-metabolic parameters. MATERIAL AND METHODS:Four hundred seventy-eight subjects, mean age 49.3±13.7years and mean BMI 31.0±6.2kg/m2, divided according to glucose tolera...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2016.11.002

    authors: Dimova R,Tankova T,Guergueltcheva V,Tournev I,Chakarova N,Grozeva G,Dakovska L

    更新日期:2017-03-01 00:00:00

  • Metformin alters peripheral blood mononuclear cells (PBMC) senescence biomarkers gene expression in type 2 diabetic patients.

    abstract:BACKGROUND:Although there is increasing evidence showing that cell senescence is increased in circulating PBMC in type 2 diabetes mellitus (T2DM), the data are contradictory. This study examined several senescence biomarkers, including LMNA/C transcript variants, p16INK4a, p53, and p21Cip1/WAF, in PBMC of T2DM patients...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2020.107758

    authors: Al Dubayee M,Alshahrani A,Almalk M,Hakami A,Homoud B,Alzneidi N,Aldhalaan J,Aljbli G,Nasr A,Farahat AI,Aljada A

    更新日期:2021-01-01 00:00:00

  • Using Tc-99m DMSA renal cortex scan to detect renal damage in women with type 2 diabetes.

    abstract::Women with diabetes mellitus (DM) have urinary tract infection (UTI) more often than women without DM. It is unknown, however, what the prevalence and type of renal damage due to UTI is in these women. Therefore, in this study, we compared type 2 DM women with or without UTI history for the prevalence and type of rena...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/s1056-8727(02)00222-2

    authors: Wu HC,Chang CH,Lai MM,Lin CC,Lee CC,Kao A

    更新日期:2003-09-01 00:00:00

  • Superoxide production and LDL oxidation by diabetic neutrophils.

    abstract::The mechanism(s) resulting in the premature atherosclerosis of diabetes is unknown. Increased phagocyte release of reactive oxygen species such as superoxide anion (O2.-), resulting in low-density lipoprotein (LDL) oxidation, could be one possible cause. The purpose of the present study was to compare the abilities of...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/1056-8727(95)00002-x

    authors: Fuller CJ,Agil A,Lender D,Jialal I

    更新日期:1996-07-01 00:00:00

  • Potential role of E4orf1 protein in aging-associated impairment in glycemic control.

    abstract::Aging constitutes a major risk factor for the development of type-2 diabetes (T2D) where glucose tolerance declines with age, resulting in a high prevalence of T2D and impaired glucose tolerance in the elderly population. Currently more than half of the 20 million U.S. adults with T2D are above the age of 60, and the ...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章,评审

    doi:10.1016/j.jdiacomp.2018.11.006

    authors: Gamage S,Reddy PH,Dhurandhar NV,Hegde V

    更新日期:2019-03-01 00:00:00

  • Long-term treatment with metformin in type 2 diabetes and methylmalonic acid: Post hoc analysis of a randomized controlled 4.3year trial.

    abstract:AIMS:Metformin treatment is associated with a decrease of serum vitamin B12, but whether this reflects tissue B12 deficiency is controversial. We studied the effects of metformin on serum levels of methylmalonic acid (MMA), a biomarker for tissue B12 deficiency, and on onset or progression of neuropathy. METHODS:In th...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2017.11.001

    authors: Out M,Kooy A,Lehert P,Schalkwijk CA,Stehouwer CDA

    更新日期:2018-02-01 00:00:00

  • Diabetes-specific dementia risk score (DSDRS) predicts cognitive performance in patients with type 2 diabetes at high cardio-renal risk.

    abstract:AIM:To investigate the relationship between the diabetes-specific dementia risk score (DSDRS) and concurrent and future cognitive impairment (CI) in type 2 diabetes (T2D). METHODS:DSDRS were calculated for participants with T2D aged ≥60 years from the CARMELINA-cognition substudy (ClinicalTrials.gov Identifier: NCT018...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2020.107674

    authors: Verhagen C,Janssen J,Exalto LG,van den Berg E,Johansen OE,Biessels GJ

    更新日期:2020-10-01 00:00:00

  • Does treatment affect the levels of serum interleukin-6, interleukin-8 and procalcitonin in diabetic foot infection? A pilot study.

    abstract:AIMS:To investigate about serum PCT, IL-6 and IL-8 levels and how they are affected by the treatment in diabetic foot patients. METHODS:Fifty patients' blood samples were taken to study ESR and CRP, IL-6, IL-8 and PCT before and at the 14th day of the treatment. RESULTS:The pretreatment results of the 50 patients sho...

    journal_title:Journal of diabetes and its complications

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.jdiacomp.2012.03.018

    authors: Altay FA,Sencan İ,Şentürk GÇ,Altay M,Güvenman S,Ünverdi S,Açıkgöz ZC

    更新日期:2012-05-01 00:00:00

  • Serum uromodulin is associated with urinary albumin excretion in adolescents with type 1 diabetes.

    abstract::Early diabetic kidney disease (DKD) occurs in adolescents with type 1 diabetes (T1D). Lower serum uromodulin (SUMOD) predicts DKD progression in adults with T1D. In this study, we demonstrate that lower SUMOD is associated with urinary albumin excretion in adolescents with T1D, suggesting a potential relationship betw...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2019.05.023

    authors: Wiromrat P,Bjornstad P,Roncal C,Pyle L,Johnson RJ,Cherney DZ,Lipina T,Bishop F,Maahs DM,Wadwa RP

    更新日期:2019-09-01 00:00:00

  • The pathophysiologic basis of efficacy and clinical experience with the new oral antidiabetic agents.

    abstract::Type 2 diabetes results from the abnormal resistance of peripheral tissues to insulin and from the progressive insulin secretory failure of the pancreatic beta-cells. Treatment of type 2 diabetes has greatly improved due to the availability of new classes of oral antidiabetic drugs (OADs) and new insulin analogs. Thre...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章,评审

    doi:10.1016/s1056-8727(01)00207-0

    authors: Rosak C

    更新日期:2002-01-01 00:00:00

  • Changes in superoxide dismutase activities and concentrations and myeloperoxidase activities in leukocytes from patients with diabetes mellitus.

    abstract::To investigate whether the two free-radical scavengers, Cu, Zn- and Mn-superoxide dismutase (SOD), are changed in leukocytes of diabetic patients, and the alteration of these enzymes correlates with the diabetic state, we measured the activity and concentration of these enzymes in leukocytes from diabetic patients. Bo...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/s1056-8727(99)00053-7

    authors: Uchimura K,Nagasaka A,Hayashi R,Makino M,Nagata M,Kakizawa H,Kobayashi T,Fujiwara K,Kato T,Iwase K,Shinohara R,Kato K,Itoh M

    更新日期:1999-09-01 00:00:00

  • Human C-reactive protein accentuates macrophage activity in biobreeding diabetic rats.

    abstract:OBJECTIVE:Type 1 diabetes (T1DM) is a pro-inflammatory state characterized by high C-reactive protein (CRP) levels. However, there is a paucity of data examining the role of CRP in promoting the pro-inflammatory state of diabetes. Thus, we examined the pro-inflammatory effects of human CRP using spontaneously diabetic ...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2012.03.020

    authors: Jialal I,Kaur H,Devaraj S

    更新日期:2013-01-01 00:00:00

  • Pernicious anemia in a patient with Type 1 diabetes mellitus and alopecia areata universalis.

    abstract::A 27-year-old male, who had developed diabetes mellitus type 1 (DMT1) since the age of eighteen and alopecia areata universalis nine months later, attended the outpatient clinics complaining of general fatigue and shortness of breath. A Schilling test was indicative of pernicious anemia. Antigastric parietal cell (AGP...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2008.05.003

    authors: Tzellos TG,Tahmatzidis DK,Lallas A,Apostolidou K,Goulis DG

    更新日期:2009-11-01 00:00:00

  • The association of cumulative discrimination on quality of care, patient-centered care, and dissatisfaction with care in adults with type 2 diabetes.

    abstract:AIMS:Discrimination is linked to negative health outcomes, but little research has investigated how the cumulative effect of discrimination impacts perceptions of care. This study investigated the influence of cumulative perceived discrimination on quality of care, patient-centeredness, and dissatisfaction with care in...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.jdiacomp.2016.09.012

    authors: Cykert DM,Williams JS,Walker RJ,Davis KS,Egede LE

    更新日期:2017-01-01 00:00:00

  • Normal blood flow response and vasomotion in the diabetic Charcot foot.

    abstract::Vasomotion, the spontaneous rhythmic contraction exhibited by small arteries and arterioles is dysregulated in patients with diabetic neuropathy. We examined the relationship between Charcot arthropathy and vasomotion at the dorsum of the foot. We studied nine diabetic patients with clinically diagnosed neuropathy and...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/s1056-8727(97)00080-9

    authors: Shapiro SA,Stansberry KB,Hill MA,Meyer MD,McNitt PM,Bhatt BA,Vinik AI

    更新日期:1998-05-01 00:00:00

  • MiR-126 overexpression inhibits high glucose-induced migration and tube formation of rhesus macaque choroid-retinal endothelial cells by obstructing VEGFA and PIK3R2.

    abstract:AIM:The aims of this study are to investigate the relative regulation between miR-126 and VEGF/PI3K/AKT signaling pathway in retinal vascular endothelial cells. METHODS:Rhesus macaque choroid-retinal endothelial cell line (RF/6A) cells were cultured in high glucose to imitate the conditions occurring in DR. First, we ...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2016.12.004

    authors: Yang WZ,Yang J,Xue LP,Xiao LB,Li Y

    更新日期:2017-04-01 00:00:00

  • Association between ApoA-II -265T/C polymorphism and oxidative stress in patients with type 2 diabetes mellitus.

    abstract:BACKGROUND:Apolipoprotein A-II (ApoA-II) constitutes approximately 20% of the total HDL protein content. The results of various studies on the relationship between cardiovascular diseases (CVD) and the plasma ApoA-II level are contradictory. The aim of this study was to determine the relationship between ApoA-II polymo...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2015.05.024

    authors: Koohdani F,Sadrzadeh-Yeganeh H,Djalali M,Eshraghian M,Keramat L,Mansournia MA,Zamani E

    更新日期:2015-09-01 00:00:00

  • Effects of a calcium channel blocker, manidipine, on insulin sensitivity in essential hypertensives.

    abstract::This study was designed to investigate the effects of the calcium channel blocker manidipine on insulin-dependent glucose uptake (insulin sensitivity) and insulin action to renal sodium handling and pressor systems in essential hypertensive (EHT). Seven EHT were hospitalized and a 2-h euglycemic hyperinsulinemic gluco...

    journal_title:Journal of diabetes and its complications

    pub_type: 临床试验,杂志文章

    doi:10.1016/1056-8727(95)80005-y

    authors: Iimura O,Shimamoto K,Masuda A,Higashiura K,Miyazaki Y,Hirata A,Fukuoka M,Murakami H

    更新日期:1995-10-01 00:00:00

  • Extracellular matrix and its interactions in the diabetic kidney: a molecular biological approach.

    abstract::Increased extracellular matrix (ECM) is the ultrastructural hallmark of diabetic microangiopathy. Its accumulation within the kidney is directly linked to the clinical manifestations of diabetic nephropathy, namely proteinuria and declining renal function. The pathogenesis of ECM changes in diabetes is not well unders...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章,评审

    doi:10.1016/1056-8727(95)80015-7

    authors: Gilbert RE,Cox A,Dziadek M,Cooper ME,Jerums G

    更新日期:1995-10-01 00:00:00

  • A retrospective review of insulin requirements in patients using U-500 insulin hospitalized to a Veterans Affairs Hospital.

    abstract:AIMS:The aim of this study was to compare the changes in the total daily dose (TDD) of insulin of patients on U-500 insulin; before hospitalization, during hospitalization and six weeks after discharge. METHODS:A retrospective chart review of veterans with type 2 diabetes receiving U-500 insulin in the ambulatory sett...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2017.02.008

    authors: Kedia R,Desouza C,Smith LM,Shivaswamy V

    更新日期:2017-05-01 00:00:00

  • Elevated beta2-glycoprotein I-low-density lipoprotein levels are associated with the presence of diabetic microvascular complications.

    abstract:AIMS:To investigate serum beta2-glycoprotein I-low-density lipoprotein (β2-GPI-LDL) and oxidized low-density lipoprotein (ox-LDL) levels in type 2 diabetes mellitus (T2DM) patients, and to further evaluate the associations of β2-GPI-LDL with ox-LDL in vivo and with the presence of diabetic microvascular complications. ...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2014.09.010

    authors: Yu R,Yuan Y,Niu D,Song J,Liu T,Wu J,Wang J

    更新日期:2015-01-01 00:00:00

  • Toe amputation: a predictor of future limb loss?

    abstract:BACKGROUND:Digital toe amputation is a relatively minor surgical procedure but there is a historical view that it is the "first stage in a predictable clinical course" leading to eventual limb loss. There is a paucity of contemporaneous data on the long-term outcomes of patients undergoing toe amputation. We aim to stu...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2012.03.003

    authors: Griffin KJ,Rashid TS,Bailey MA,Bird SA,Bridge K,Scott JD

    更新日期:2012-05-01 00:00:00

  • Insulin resistance since early adulthood and appendicular lean mass in middle-aged adults without diabetes: 20 years of the CARDIA study.

    abstract:AIMS:To determine the association between 20-year trajectories in insulin resistance (IR) since young adulthood and appendicular lean mass (ALM) at middle-age in adults without diabetes. METHODS:A prospective cohort study was designed among young and middle-aged US men (n = 925) and women (n = 1193). Fasting serum glu...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2018.09.011

    authors: Zhong VW,Bancks MP,Schreiner PJ,Lewis CE,Steffen LM,Meigs JB,Schrader LA,Schorr M,Miller KK,Sidney S,Carnethon MR

    更新日期:2019-01-01 00:00:00

  • The effect of achieving a systolic blood pressure of 140 mmHg. A prospective study of ambulatory measurements in type 2 diabetic patients with nephropathy.

    abstract:OBJECTIVES:What is the prognostic significance of achieving a systolic blood pressure of <140 mmHg? SETTING:Diabetic renal policlinic, university hospital of Lund, Sweden. SUBJECTS:118 type 2 diabetic patients with micro-macroalbuminuria were followed for four years (range 1-8 years). METHOD AND MAIN OUTCOME MEASURES...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2012.05.020

    authors: Torffvit O

    更新日期:2012-11-01 00:00:00

  • Increased orosomucoid in urine is an independent predictor of cardiovascular and all-cause mortality in patients with type 2 diabetes at 10 years of follow-up.

    abstract:AIMS:To evaluate whether increased urinary orosomucoid excretion rate (UOER) is an independent predictor of cardiovascular and all-cause mortality in type 2 diabetes (T2DM) and type 1 diabetes (T1DM) at 10years of follow-up. METHOD:We followed 430 patients with T2DM and 148 patients with T1DM until emigration, death o...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2013.05.008

    authors: Svendstrup M,Christiansen MS,Magid E,Hommel E,Feldt-Rasmussen B

    更新日期:2013-11-01 00:00:00

  • Patients with type 2 diabetes having higher glomerular filtration rate showed rapid renal function decline followed by impaired glomerular filtration rate: Japan Diabetes Complications Study.

    abstract:AIMS:The Japan Diabetes Complications Study (JDCS), a nation-wide, multicenter, prospective study of patients with type 2 diabetes, reported that hemoglobin A1c (HbA1c), systolic blood pressure, and smoking were risk factors for the onset of macroalbuminuria. This study explored the risk factors for glomerular filtrati...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.jdiacomp.2016.06.020

    authors: Moriya T,Tanaka S,Sone H,Ishibashi S,Matsunaga S,Ohashi Y,Akanuma Y,Haneda M,Katayama S

    更新日期:2017-02-01 00:00:00

  • High absolute risk of severe infections among Indigenous adults in rural northern Australia is amplified by diabetes - A 7 year follow up study.

    abstract:AIMS:To quantify the risk of hospitalization for infections in Indigenous Australian adults with diabetes in rural and remote communities. METHODS:2787 Indigenous adults including 396 with diabetes at baseline from 19 communities in North Queensland from 1998 to 2007 were included in the study. Main measures were weig...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2016.04.022

    authors: Li M,McDermott R

    更新日期:2016-08-01 00:00:00