abstract：AIMS:To examine the effects of strict glycemic control on the birthweight of infants born to Japanese patients with early- or mid-to-late-detected gestational diabetes mellitus (ed- or md-GDM). METHODS:We retrospectively examined the characteristics of 101 patients with GDM who underwent guideline-based glycemic contr...

journal_title：Journal of diabetes and its complications

authors： Yasuda S,Inoue K,Iida S,Oikawa Y,Namba A,Isshiki M,Inoue I,Kamei Y,Shimada A,Noda M

更新日期：2021-01-09 00:00:00

abstract：:Recent studies suggest that the accumulation of atypical, 1-deoxysphingolipids that lack the C1 hydroxyl group may be associated with diabetic neuropathy (DN). We hypothesized that specific plasma 1-deoxysphingolipids associate with DN severity, and that alterations in plasma serine and alanine associate with 1-deoxys...

journal_title：Journal of diabetes and its complications

authors： Fridman V,Zarini S,Sillau S,Harrison K,Bergman BC,Feldman EL,Reusch JEB,Callaghan BC

更新日期：2021-01-09 00:00:00

abstract：BACKGROUND:Although there is increasing evidence showing that cell senescence is increased in circulating PBMC in type 2 diabetes mellitus (T2DM), the data are contradictory. This study examined several senescence biomarkers, including LMNA/C transcript variants, p16INK4a, p53, and p21Cip1/WAF, in PBMC of T2DM patients...

journal_title：Journal of diabetes and its complications

authors： Al Dubayee M,Alshahrani A,Almalk M,Hakami A,Homoud B,Alzneidi N,Aldhalaan J,Aljbli G,Nasr A,Farahat AI,Aljada A

更新日期：2021-01-01 00:00:00

abstract：:Diabetes mellitus (DM) can lead to the development of macro- and microvascular complications. Homocysteine (Hcy) may play a role in the development of cardiovascular (CV) diseases (CVDs). The role of Hcy in the development of the vascular complications associated with DM is not clearly defined. Despite a strong initia...

journal_title：Journal of diabetes and its complications

authors： Muzurović E,Kraljević I,Solak M,Dragnić S,Mikhailidis DP

更新日期：2020-12-31 00:00:00

abstract：AIMS:To assess the impact of diabetic foot care delivery in preventing lower extremity amputation (LEA). METHODS:We systematically searched the MEDLINE database for research evaluating the association between any aspect of diabetic foot care delivery and risk of LEA. Meta-analysis was conducted by calculating a pooled...

journal_title：Journal of diabetes and its complications

authors： Monteiro-Soares M,Vale-Lima J,Martiniano J,Pinheiro-Torres S,Dias V,Boyko EJ

更新日期：2020-12-31 00:00:00

abstract：OBJECTIVE:Patients with silent and undiagnosed paroxysmal atrial fibrillation and flutter (AF) have increased risk of ischemic stroke. Patients with diabetes have a higher risk of both AF and ischemic stroke compared to patients without diabetes. Our aim was to investigate the prevalence of silent AF in patients with d...

journal_title：Journal of diabetes and its complications

authors： Højager A,Tingsgaard JK,Andersen D,Søholm H,Taskiran M,Bock TG,Schoos MM

更新日期：2020-12-01 00:00:00

abstract：AIMS:Albuminuria and reduced glomerular filtration rate (GFR) are manifestations of diabetic kidney disease and are both shown to be associated with cardiovascular outcomes. However, the differential association of albuminuria and reduced GFR with endothelial dysfunction, an early feature of atherosclerotic vascular da...

journal_title：Journal of diabetes and its complications

authors： Kakutani Y,Morioka T,Mori K,Yamazaki Y,Ochi A,Kurajoh M,Fukumoto S,Shioi A,Shoji T,Inaba M,Emoto M

更新日期：2020-12-01 00:00:00

abstract：AIMS:To estimate the cost of diabetes complications in the United States (U.S.). METHODS:We constructed longitudinal panel data using one of the largest claims databases in the U.S. for privately insured Type 1 (T1DM) and type 2 (T2DM) diabetes patients with a follow-up time of one to ten years. Complication costs wer...

journal_title：Journal of diabetes and its complications

authors： Yang W,Cintina I,Hoerger T,Neuwahl SJ,Shao H,Laxy M,Zhang P

更新日期：2020-12-01 00:00:00

abstract：AIMS:To investigate the effect of a single nucleotide polymorphism (SNP) in transmembrane protein 182 (TMEM182) on the risk of having central obesity and the related phenotype. METHODS:In total, 2141 subjects with central obesity (n = 827) and normal controls (n = 1314) were included. The most strongly associated SNPs...

journal_title：Journal of diabetes and its complications

authors： Ma M,Lee JH,Kim M

更新日期：2020-12-01 00:00:00

abstract：AIMS:To investigate the impact of time in range (TIR) on mood in adults with type 1 diabetes (T1D). METHODS:We followed a cohort of 219 T1D adults, all currently employing a real-time continuous glucose monitoring system (RT-CGM), to investigate how daily changes in CGM metrics were associated with nightly reports of ...

journal_title：Journal of diabetes and its complications

authors： Polonsky WH,Fortmann AL

更新日期：2020-12-01 00:00:00

abstract：AIMS:Data on involvement of paraoxonase 1 gene (PON1) in non-insulin-dependent diabetes mellitus (NIDDM) nephropathy are scarce. We investigated PON1 polymorphisms concerning end-stage NIDDM nephropathy and atherosclerotic complications in NIDDM nephropathy patients treated with hemodialysis (HD). METHODS:In NIDDM nep...

journal_title：Journal of diabetes and its complications

authors： Grzegorzewska AE,Ostromecka K,Adamska P,Mostowska A,Warchoł W,Jagodziński PP

更新日期：2020-11-01 00:00:00

abstract：AIMS:To assess the effects of plerixafor on function and endothelial regeneration of endothelial progenitor cells (EPCs). METHODS:The proliferation and adhesion capacity of EPCs were evaluated in vitro. Furthermore, the expression levels of CXC chemokine receptor-7 (CXCR7) were detected before and after treatment with...

journal_title：Journal of diabetes and its complications

authors： Jiang C,Li R,Ma X,Hu H,Wei L,Zhao J

更新日期：2020-10-01 00:00:00

abstract：AIM:To investigate the relationship between the diabetes-specific dementia risk score (DSDRS) and concurrent and future cognitive impairment (CI) in type 2 diabetes (T2D). METHODS:DSDRS were calculated for participants with T2D aged ≥60 years from the CARMELINA-cognition substudy (ClinicalTrials.gov Identifier: NCT018...

journal_title：Journal of diabetes and its complications

authors： Verhagen C,Janssen J,Exalto LG,van den Berg E,Johansen OE,Biessels GJ

更新日期：2020-10-01 00:00:00

abstract：AIM:To evaluate the efficacy and safety of iGlarLixi in Mexican patients with type 2 diabetes who participated in the LixiLan clinical trials and compare results with the rest of the patients. METHODS:Data was collected for Mexican patients who participated in either of three studies: phase 2 trial LixiLan-POC, that c...

journal_title：Journal of diabetes and its complications

authors： González-Gálvez G,Díaz-Toscano ML,Llamas-Moreno JF,Fernández-Rodarte K,Sañudo-Maury ME

更新日期：2020-08-01 00:00:00

abstract：AIMS:To investigate the relationship of unawareness of hypoglycemia with spectral analysis of heart rate variability (HRV) and clinical variables in type 1 diabetes (T1D) individuals. METHODS:Participants with type 1 diabetes mellitus (type 1 diabetes) were prospectively assessed for hypoglycemia awareness using the P...

journal_title：Journal of diabetes and its complications

authors： Paes T,Rolim LC,Filho CS,de Sa JR,Dib SA

更新日期：2020-08-01 00:00:00

abstract：AIMS:Previous studies have reported beneficial effects of chronic resistance exercise in the prevention and treatment of type 2 diabetes. To clarify potential modulators of acute responses to resistance exercise, we reviewed the literature to determine the effects of a single bout of resistance exercise on cardiometabo...

journal_title：Journal of diabetes and its complications

authors： Brown EC,Franklin BA,Regensteiner JG,Stewart KJ

更新日期：2020-08-01 00:00:00

abstract：AIMS:The purpose of this study was to investigate the impact of diabetic neuropathy (dNP) on lower limb endurance, explosive and maximal muscle strength in patients with Type 2 Diabetes Mellitus (T2DM). METHODS:Fifty-four participants, aged between 55 and 85, were enrolled in this observational comparative study. The ...

journal_title：Journal of diabetes and its complications

authors： Van Eetvelde BLM,Lapauw B,Proot P,Vanden Wyngaert K,Celie B,Cambier D,Calders P

更新日期：2020-06-01 00:00:00

abstract：AIMS:To investigate the predictive capability of insulin resistance surrogate markers for insulin resistance and arterial stiffness based on sex. METHODS:We assessed the association of triglyceride glucose (TyG) index, triglyceride to high-density lipoprotein cholesterol ratio (TG/HDL-C), visceral adiposity index (VAI...

journal_title：Journal of diabetes and its complications

authors： Nakagomi A,Sunami Y,Kawasaki Y,Fujisawa T,Kobayashi Y

更新日期：2020-06-01 00:00:00

abstract：AIMS:Increased adiposity is a risk factor for suboptimal diabetes control and cardiovascular disease (CVD) complications. Our goal was to identify modifiable behavioral characteristics of overweight and obese pediatric patients with type 1 diabetes mellitus (T1DM) who achieve optimal glycemic control and to evaluate th...

journal_title：Journal of diabetes and its complications

authors： Flokas ME,Zeymo A,Mete M,Anhalt H,Rother KI,Gourgari E

更新日期：2020-04-01 00:00:00

abstract：AIMS:Our study aimed to investigate associations between BMI, waist circumference (WC), and central obesity (CO) with outcomes in patients with type 2 diabetes using data from the ACCORD trial. METHODS:WC was assessed as a continuous variable. CO was derived as a dichotomous variable using cutoffs from the World Healt...

journal_title：Journal of diabetes and its complications

authors： German CA,Laughey B,Bertoni AG,Yeboah J

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Although lifestyle modifications are known to be effective in type 2 diabetes (T2D) as well as in prediabetes, adherence to a healthy diet is difficult for some, and interventions of lifestyle modifications need to be revised occasionally. Meal sequence has been gaining attention as a part of a healthy diet ...

journal_title：Journal of diabetes and its complications

authors： Yabe D,Kuwata H,Fujiwara Y,Sakaguchi M,Moyama S,Makabe N,Murotani K,Asano H,Ito S,Mishima H,Takase H,Ota N,Seino Y,Hamamoto Y,Kurose T,Seino Y

更新日期：2019-12-01 00:00:00

abstract：AIMS:The aim of this study is to investigate the effects of a low-carbohydrate staple food (i.e., low-carbohydrate bread) on glucose and lipid metabolism and pancreatic and enteroendocrine hormone secretion in comparison with meals containing normal-carbohydrate bread, without consideration of the carbohydrate content ...

journal_title：Journal of diabetes and its complications

authors： Kondo-Ando M,Seino Y,Morikawa R,Negi K,Todoroki H,Kawakami T,Asada Y,Yoshimoto R,Tanaka C,Okamoto K,Masuda A,Tomatsu E,Hiratsuka I,Yoshino Y,Maki W,Kakita A,Shibata M,Takayanagi T,Makino M,Sugimura Y,Asai S,Ito

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVE:Although diabetic kidney disease (DKD) has been considered as a glomerulocentric disease in the past few decades, growing evidence demonstrated that tubular damage was indispensable in its pathogenesis and progression. This study was designed to investigate the association of urinary acidification dysfunction...

journal_title：Journal of diabetes and its complications

authors： Zhu H,Liu X,Zhang C,Li Q,An X,Liu S,Wu L,Zhang B,Yuan Y,Xing C

更新日期：2019-11-01 00:00:00

abstract：:Although slow gastric emptying (gastroparesis) is a well-known complication of chronic hyperglycemia in diabetes mellitus (DM), it recently has become clear that rapid gastric emptying also is a frequent and important diabetic complication. In contrast, acute hyperglycemia causes slow gastric emptying, and acute hypog...

journal_title：Journal of diabetes and its complications

authors： Goyal RK,Cristofaro V,Sullivan MP

更新日期：2019-11-01 00:00:00

abstract：INTRODUCTION:Patients with diabetes and diabetic peripheral neuropathy (DPN) place their feet with less accuracy whilst walking, which may contribute to the increased falls-risk. This study examines the effects of a multi-faceted intervention on stepping accuracy, in patients with diabetes and DPN. METHODS:Forty parti...

journal_title：Journal of diabetes and its complications

authors： Handsaker JC,Brown SJ,Petrovic M,Bowling FL,Rajbhandari S,Marple-Horvat DE,Boulton AJM,Reeves ND

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:To determine if serum pigment epithelium-derived factor (PEDF) levels predict cardiovascular events, renal dysfunction and mortality in the Veterans Affairs Diabetes Study (VADT). METHODS:PEDF was evaluated in relation to subsequent cardiovascular outcomes, mortality, and renal dysfunction (defined as urina...

journal_title：Journal of diabetes and its complications

authors： Hunt KJ,Jenkins AJ,Fu D,Stevens D,Ma JX,Klein RL,Azar M,Zhang SX,Lopes-Virella MF,Lyons TJ,VADT Investigators.

更新日期：2019-10-01 00:00:00

abstract：:Early diabetic kidney disease (DKD) occurs in adolescents with type 1 diabetes (T1D). Lower serum uromodulin (SUMOD) predicts DKD progression in adults with T1D. In this study, we demonstrate that lower SUMOD is associated with urinary albumin excretion in adolescents with T1D, suggesting a potential relationship betw...

journal_title：Journal of diabetes and its complications

authors： Wiromrat P,Bjornstad P,Roncal C,Pyle L,Johnson RJ,Cherney DZ,Lipina T,Bishop F,Maahs DM,Wadwa RP

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND AND AIMS:Attenuated retinal vasoreactivity in patients with type 2 diabetes preceding diabetic retinopathy development has been proposed to reflect local endothelial dysfunction. Whether retinal vessel reactivity is associated with peripheral endothelial dysfunction and large artery stiffness in patients wit...

journal_title：Journal of diabetes and its complications

authors： Baier JM,Funck KL,Petersen L,Vernstrøm L,Knudsen ST,Bek T,Poulsen PL,Laugesen E

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:We investigated the clinical relevance of non-albumin proteinuria (NAP) in Korean patients with type 2 diabetes (T2D). RESEARCH DESIGN AND METHODS:We enrolled 883 T2D patients who had both their urinary albumin-to-creatinine ratio (uACR) and protein-to-creatinine ratio (uPCR) measured. We classified the pati...

journal_title：Journal of diabetes and its complications

authors： Cho Y,Lee YH,Kang ES,Cha BS,Lee BW

更新日期：2019-08-01 00:00:00

abstract：AIMS:To compare microvascular and macrovascular complication rates among Ghanaians with type 2 diabetes (T2D) living in Ghana and in three European cities (Amsterdam, London and Berlin). METHODS:Data from the multicenter Research on Obesity and Diabetes among African Migrants (RODAM) study were analyzed. 650 Ghanaian ...

journal_title：Journal of diabetes and its complications

authors： Hayfron-Benjamin C,van den Born BJ,Maitland-van der Zee AH,Amoah AGB,Meeks KAC,Klipstein-Grobusch K,Bahendeka S,Spranger J,Danquah I,Mockenhaupt F,Beune E,Smeeth L,Agyemang C

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:The ASGR1 was recently shown to play a key role in the development of coronary artery disease (CAD), but its exact mechanism of action in the CAD pathogenesis is not yet known. This study evaluates the possible association between the expression level of ASGR1 and its downstream transcription factor FOXM1 in...

journal_title：Journal of diabetes and its complications

authors： Hamledari H,Sajjadi SF,Alikhah A,Boroumand MA,Behmanesh M

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVE:MicroRNAs (miRNAs) have emerged as promising regulators of diabetes mellitus (DM)-induced angiogenic dysfunction in endothelial cells (ECs), but information vis-à-vis the functional roles of distinct miRNAs remain surprisingly scarce. The current study was designed to elucidate the expression and function of ...

journal_title：Journal of diabetes and its complications

authors： Wang D,Wang H,Liu C,Mu X,Cheng S

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Glomerular hyperfiltration is not able to be detected in clinical practice. We assessed whether hyperfiltration is associated with albuminuria progression among Indigenous Australians at high risk of diabetes and kidney disease to determine its role in kidney disease progression. METHODS:Longitudinal observ...

journal_title：Journal of diabetes and its complications

authors： Ekinci EI,Barr ELM,Barzi F,Hughes JT,Lawton PD,Jones GRD,Hoy W,Cass A,Thomas M,Sinha A,Jerums G,O'Dea K,MacIsaac RJ,Maple-Brown LJ

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Lower serum concentrations of the osteoblast-derived protein, osteocalcin, have been associated with poorer glycemic control, insulin resistance and atherosclerosis, and with the development of type 2 diabetes (T2DM). METHODS:This study compares concentrations of two physiological forms of osteocalcin, carb...

journal_title：Journal of diabetes and its complications

authors： Darwish L,Nguyen MM,Saleem M,Eakin KA,Herrmann N,Sugamori KS,Oh PI,Yang P,Mitchell J,Lanctôt KL,Swardfager W

更新日期：2019-05-01 00:00:00

abstract：:Aging constitutes a major risk factor for the development of type-2 diabetes (T2D) where glucose tolerance declines with age, resulting in a high prevalence of T2D and impaired glucose tolerance in the elderly population. Currently more than half of the 20 million U.S. adults with T2D are above the age of 60, and the ...

journal_title：Journal of diabetes and its complications

authors： Gamage S,Reddy PH,Dhurandhar NV,Hegde V

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVE:The TG/HDL-C ratio is used as a marker of insulin resistance (IR) in Caucasians; however, there is limited data in other ethnic groups. We hypothesized that the TG/HDL-C ratio is associated with IR in Hispanics and African Americans (AA). RESEARCH DESIGN AND METHODS:Data from the Insulin Resistance Atheroscl...

journal_title：Journal of diabetes and its complications

authors： Young KA,Maturu A,Lorenzo C,Langefeld CD,Wagenknecht LE,Chen YI,Taylor KD,Rotter JI,Norris JM,Rasouli N

更新日期：2019-02-01 00:00:00

abstract：:Radial pulse spectrum has been shown to correlate with coronary stenosis in patients with type 2 diabetes mellitus (T2DM). In academia, it has not been demonstrated that the radial artery pulse spectrum is an independent risk factor for major adverse cardiovascular events (MACE), including myocardial infarction, strok...

journal_title：Journal of diabetes and its complications

authors： Chang CW,Liao KM,Chang YT,Wang SH,Chen YC,Wang GC

更新日期：2019-02-01 00:00:00

abstract：AIMS:Diabetic nephropathy (DN) that progress to end stage renal failure is a serious health problem. Autophagy is involved in DN pathogenesis. Finding renal prognostic biomarkers can help in the future renal status prevision. Therefore, the aim of current study was to evaluate and correlate circulating levels of autoph...

journal_title：Journal of diabetes and its complications

authors： El-Shazly AAA,Sallam AM,El-Hefnawy MH,El-Mesallamy HO

更新日期：2019-02-01 00:00:00

abstract：AIMS:Young-onset T2D (YT2D) is associated with a more fulminant course and greater propensity for diabetic complications. The association of PAX4 R192H (rs2233580) variation with YT2D was inconsistent partly because of its Asian-specificity and under-representation of Asians in international consortiums. Interestingly,...

journal_title：Journal of diabetes and its complications

authors： Ang SF,Tan CSH,Wang L,Dorajoo R,Fong JCW,Kon WYC,Lian JX,Ang K,Rahim JB,Jeevith B,Lee SBM,Tang WE,Subramanium T,Sum CF,Liu JJ,Lim SC

更新日期：2019-01-01 00:00:00

abstract：AIMS:To determine the association between 20-year trajectories in insulin resistance (IR) since young adulthood and appendicular lean mass (ALM) at middle-age in adults without diabetes. METHODS:A prospective cohort study was designed among young and middle-aged US men (n = 925) and women (n = 1193). Fasting serum glu...

journal_title：Journal of diabetes and its complications

authors： Zhong VW,Bancks MP,Schreiner PJ,Lewis CE,Steffen LM,Meigs JB,Schrader LA,Schorr M,Miller KK,Sidney S,Carnethon MR

更新日期：2019-01-01 00:00:00