Dialysis of isolated low density lipoprotein induces a loss of lipophilic antioxidants and increases the susceptibility to oxidation in vitro.

abstract：:The well established 'systemic' risk factors for atherosclerosis can explain only half of the variability in its occurrence. To account for some of the remaining variability, it was suggested that certain geometric features of atherosclerosis-prone segments ('geometric risk factors') can increase the likelihood of dis...

journal_title：Atherosclerosis

authors： Friedman MH,Baker PB,Ding Z,Kuban BD

更新日期：1996-09-06 00:00:00

abstract：:Incorporation of 125I-labeled cholesterol ester rich lipoproteins from cholesterol fed rabbits into normal rabbit aorta in vitro was inhibited by heparin, lecithin, and collagenase and by succinylation of the lipoprotein. Aortic uptake of lipoprotein was increased by neuraminidase, proteases, lipase, and beta-glucuron...

journal_title：Atherosclerosis

authors： Day CE

更新日期：1976-11-01 00:00:00

abstract：OBJECTIVE:To investigate SCM-198 (also known as "leonurine"), a compound in Herba leonuri, as well as its effect on the progression of atherosclerosis in hypercholesterolemic rabbits and underlying mechanisms. METHODS:Thirty New Zealand male White rabbits (5 groups, n = 6) were fed either a normal diet or a high-chole...

journal_title：Atherosclerosis

authors： Zhang Y,Guo W,Wen Y,Xiong Q,Liu H,Wu J,Zou Y,Zhu Y

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND AND AIMS:Galectin-3 binding protein (Gal-3BP) has been associated with inflammation and cancer, however, its role in coronary artery disease (CAD) and cardiovascular outcome remains unclear. METHODS:Gal-3BP plasma levels were measured by ELISA in 2922 individuals from the LURIC study (62.7 ± 10.6 years, 62....

journal_title：Atherosclerosis

authors： Gleissner CA,Erbel C,Linden F,Domschke G,Akhavanpoor M,Helmes CM,Doesch AO,Kleber ME,Katus HA,Maerz W

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVES:This study tests the validity of the Hattori formula to calculate LDL apoB based on plasma lipids and total apoB. METHODS:In 2178 patients in a tertiary care lipid clinic, LDL apoB calculated as suggested by Hattori et al. was compared to directly measured LDL apoB isolated by ultracentrifugation. RESULTS:...

journal_title：Atherosclerosis

authors： Sniderman AD,Tremblay AJ,De Graaf J,Couture P

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:Subjects with metabolic syndrome (MetS) and individuals with type 2 diabetes are at high risk for vascular complications. Hormones acting on vascular endothelium may be involved in the atherogenic process associated with metabolic disorders. The objective of this study was to determine the correlation of pro-...

journal_title：Atherosclerosis

authors： Then C,Kowall B,Lechner A,Meisinger C,Heier M,Koenig W,Peters A,Thiery J,Rathmann W,Seissler J

更新日期：2013-10-01 00:00:00

abstract：:Administration of ursodeoxycholic acid (UDCA) has been shown to decrease serum total and low density lipoprotein (LDL) cholesterol in hypercholesterolemic patients with primary biliary cirrhosis. Results of previous studies prompted us to postulate that the cholesterol-lowering effect of UDCA may be due, at least in p...

journal_title：Atherosclerosis

authors： Ceryak S,Bouscarel B,Malavolti M,Robins SJ,Caslow KL,Fromm H

更新日期：2000-11-01 00:00:00

abstract：:We have recently established that low density lipoprotein (LDL) of most patients with coronary atherosclerosis differs from the LDL of most healthy subjects by its ability to cause primary atherosclerotic changes, i.e. the accumulation of intracellular cholesterol in the cells of smooth muscle origin cultured from una...

journal_title：Atherosclerosis

authors： Orekhov AN,Tertov VV,Mukhin DN

更新日期：1991-02-01 00:00:00

abstract：:The effectiveness of a new, almost l-thyroxine free preparation of d-thyroxine (Dynothel) was tested in 15 patients with Type IIa and 4 patients with Type IIb hyperlipoproteinemia. Eleven patients with Type IIa and 3 with Type IIb were responsive to treatment and showed an average 26% decrease in plasma TC. This decre...

journal_title：Atherosclerosis

authors： Rakow AD,Klor HU,Kuter E,Ditschuneit HH,Ditschuneit H

更新日期：1976-09-01 00:00:00

abstract：:In a randomized, double-blind, crossover trial of 5-week treatment period with placebo or rosuvastatin (10 or 40 mg/day) with 2-week placebo wash-outs between treatments, the dose-dependent effect of rosuvastatin on apolipoprotein (apo) B-100 kinetics in metabolic syndrome subjects were studied. Compared with placebo,...

journal_title：Atherosclerosis

authors： Ooi EM,Barrett PH,Chan DC,Nestel PJ,Watts GF

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Mutations in the LDL receptor gene are the major cause of familial hypercholesterolaemia (FH) but it has been previously shown that the simple finding of a variation in the coding sequence of the LDLR does not confirm that it is the actual cause of FH. The pathogenicity of five missense alterations in the LD...

journal_title：Atherosclerosis

authors： Silva S,Alves AC,Patel D,Malhó R,Soutar AK,Bourbon M

更新日期：2012-11-01 00:00:00

abstract：:Histologic features of aortic fatty streaks were examined in male subjects aged 10-39 from Guatemala, Jamaica Negro, Durban Bantu, New Orleans Negro, New Orleans white, Lima and Santiago. These groups were selected from the 19 available in the IAP (International Atherosclerosis Project) because they represented the gr...

journal_title：Atherosclerosis

authors： Restrepo C,Tracy RE

更新日期：1975-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Carbohydrates and fat intake have both been linked to development of atherosclerosis. We examined associations between glycemic index (GI) and fat intake with carotid atherosclerosis. METHODS:The Atherosclerosis Risk in Communities (ARIC) cohort enrolled participants during the period 1987-1989 and...

journal_title：Atherosclerosis

authors： Dearborn JL,Qiao Y,Guallar E,Steffen LM,Gottesman RF,Zhang Y,Wasserman BA

更新日期：2016-08-01 00:00:00

abstract：:When smoke from single cigarettes containing [4-14C]cholesterol or beta-[4-14C]sitosterol was delivered to the lungs of Rhesus macaques, plasma contained radiolabeled sterols up to 50 days later. Since cholesterol, as well as plant sterols (campesterol, stigmasterol and beta-sitosterol), are normally present in cigare...

journal_title：Atherosclerosis

authors： Malinow MR,McLaughlin P,Aigner-Held R,Upson B,Isabelle LM,Connor WE,Lin D

更新日期：1986-04-01 00:00:00

abstract：:Male adult New Zealand rabbits were fed a 2% cholesterol diet for 60 days followed by 10, 20, or 30 days of normal low cholesterol diet. Collagen synthesis was estimated by measuring aortic prolyl hydroxylase activity. Tissue cholesterol accumulation rates were estimated by dividing total tissue cholesterol by the num...

journal_title：Atherosclerosis

authors： Modrak JB,Langner RO

更新日期：1980-10-01 00:00:00

abstract：:The beneficial therapeutic effects of raising HDL cholesterol are proving difficult to confirm in humans. The evaluation of antiatherogenic functions of HDL is an important area of research which includes the role of HDL in reverse cholesterol transport (RCT), especially macrophage-specific RCT, and its antioxidant an...

journal_title：Atherosclerosis

authors： Escolà-Gil JC,Rotllan N,Julve J,Blanco-Vaca F

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Eosinophils have been involved in a wide spectrum of pro-inflammatory and pro-thrombotic conditions, with the development of cardiovascular complications in a significant proportion of hypereosinophilic patients. However, no study has so far evaluated the impact of eosinophils levels on periprocedural myocar...

journal_title：Atherosclerosis

authors： Verdoia M,Schaffer A,Barbieri L,Sinigaglia F,Marino P,Suryapranata H,De Luca G,Novara Atherosclerosis Study Group (NAS).

更新日期：2014-09-01 00:00:00

abstract：:Intact platelets from atherosclerotic rabbits release more thromboxane B2 (TXB2) and 12-hydroxyeicosatetraenoic acid (HETE) than platelets from normal rabbits following incubation with [14C]arachidonic acid (AA). In contrast, no difference is found between homogenates of platelets from normal and atherosclerotic anima...

journal_title：Atherosclerosis

authors： Dembińska-Kièć A,Rücker W,Schönhöfer PS

更新日期：1979-06-01 00:00:00

abstract：:Serum high density lipoprotein cholesterol (HDL-C), total cholesterol (TC) and triglycerides (TG) were determined, and values of low density lipoprotein cholesterol (LDL-C), HDL-C/TC (%), and the LDL-C/HDL-C (ratio) were calculated in 1101 healthy Chinese men and women, 77 patients with coronary heart disease (CHD), 7...

journal_title：Atherosclerosis

authors： Cai HJ,Li ZX,Yang SM

更新日期：1982-06-01 00:00:00

abstract：:The hypolipidemic efficacy of ciprofibrate was evaluated in patients with type II hypercholesterolemia. Patients were randomized to placebo or ciprofibrate (50 mg or 100 mg/day) and, after a 6-week baseline period, received medication for a period of 12 weeks. Blood samples were analyzed every 2 weeks. Twenty patients...

journal_title：Atherosclerosis

authors： Illingworth DR,Olsen GD,Cook SF,Sexton GJ,Wendel HA,Connor WE

更新日期：1982-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Carotid artery plaque is an established marker of subclinical atherosclerosis and common patho-mechanisms with coronary artery disease (CAD) are hypothesized. We aimed to identify genetic variants associated with carotid plaque and to examine the potential shared genetic basis with CAD. METHODS:Aft...

journal_title：Atherosclerosis

authors： Pott J,Burkhardt R,Beutner F,Horn K,Teren A,Kirsten H,Holdt LM,Schuler G,Teupser D,Loeffler M,Thiery J,Scholz M

更新日期：2017-04-01 00:00:00

abstract：:Abdominal aortic aneurysm (AAA) and atherosclerosis are common causes of mortality and morbidity in an aging population. Angiogenesis is believed to contribute to the development and progression of these diseases. Angiopoietins (angpts) are known to be important regulators of angiogenesis. Angpts can also influence in...

journal_title：Atherosclerosis

authors： Trollope AF,Golledge J

更新日期：2011-02-01 00:00:00

abstract：:The effect of the apolipoprotein C-II/C-III1 ratio on the capacity of purified bovine milk lipoprotein lipase to hydrolyse triglycerides was measured in a controlled model of pyrene-labeled nonanoyltriglycerides (1-2 ditetradecyl 3-pyrene nonanoyl glyceride) monolayer vesicles. Monolayer was composed of triglycerides,...

journal_title：Atherosclerosis

authors： Lambert DA,Catapano AL,Smith LC,Sparrow JT,Gotto AM Jr

更新日期：1996-12-20 00:00:00

abstract：:We measured 381 genomewide markers and performed genetic linkage analyses in search of loci influencing coronary artery calcification (CAC), a measure of atherosclerosis determined by electron beam computed tomography, in 948 non-Hispanic white siblings (mean age [+/-standard deviation] = 59.6 +/- 9.9 years; 73.7% hyp...

journal_title：Atherosclerosis

authors： Turner ST,Peyser PA,Kardia SL,Bielak LF,Sheedy PF 3rd,Boerwinkle E,de Andrade M

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Early detection of atrial fibrillation after stroke is important for secondary prevention in stroke patients without known atrial fibrillation (AF). We aimed to compare the performance of CHADS2, CHA2DS2-VASc and HATCH scores in predicting AF detected after stroke (AFDAS) and to test whether adding ...

journal_title：Atherosclerosis

authors： Hsieh CY,Lee CH,Wu DP,Sung SF

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:Toll-like receptor (TLR)-4 signalling has been shown to accelerate atherosclerosis. As oxidised phospholipids are present in atherosclerotic plaque and have been shown to modulate TLR4 signalling, we investigated the role of oxidised 1-palmitoyl-2-arachidonyl-sn-glycero-3-phosphorylcholine (OxPAPC) in the reg...

journal_title：Atherosclerosis

authors： Erridge C,Webb DJ,Spickett CM

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVE:Alterations of wall shear stress can predispose the endothelium to the development of atherosclerotic plaques. Ample evidence indicates that arginase expression and/or activity correlates with several risk factors for cardiovascular disease including atherosclerosis. We investigated the regulation of arginase...

journal_title：Atherosclerosis

authors： Thacher TN,Gambillara V,Riche F,Silacci P,Stergiopulos N,da Silva RF

更新日期：2010-05-01 00:00:00

abstract：:Diabetes mellitus is one of the major risk factors for coronary artery disease (CAD). A recent study reported that glimepiride, a new third-generation sulfonylurea, inhibited the formation of atheromatous plaques in high-cholesterol fed rabbits. However, the mechanism by which glimepiride induces atheroprotection rema...

journal_title：Atherosclerosis

authors： Ueba H,Kuroki M,Hashimoto S,Umemoto T,Yasu T,Ishikawa SE,Saito M,Kawakami M

更新日期：2005-11-01 00:00:00

abstract：:The heavy and light subfractions of low density lipoprotein (LDL) were bound to the same extent and with the same affinity by the LDL receptors of cultured human fibroblasts, both when assayed at 4 degrees C and when assayed at 37 degrees C. They were also degraded similarly by the low affinity, LDL-receptor-mediated ...

journal_title：Atherosclerosis

authors： Knight BL,Thompson GR,Soutar AK

更新日期：1986-03-01 00:00:00

abstract：OBJECTIVE:We aimed to determine, whether the amount of local pericoronary fat volume is associated with the presence of plaque burden in the underlying coronary artery segment. METHODS:We assessed 311 coronary segments from ECG-gated contrast-enhanced dual-source computed tomography for presence of plaque as well as s...

journal_title：Atherosclerosis

authors： Mahabadi AA,Reinsch N,Lehmann N,Altenbernd J,Kälsch H,Seibel RM,Erbel R,Möhlenkamp S

更新日期：2010-07-01 00:00:00