Angiopoietins, abdominal aortic aneurysm and atherosclerosis.

Abstract:

:Abdominal aortic aneurysm (AAA) and atherosclerosis are common causes of mortality and morbidity in an aging population. Angiogenesis is believed to contribute to the development and progression of these diseases. Angiopoietins (angpts) are known to be important regulators of angiogenesis. Angpts can also influence inflammation and have been shown to possess both pro-atherosclerotic and atheroprotective effects. This review explores the potential roles that the angpts play in the development and progression of AAA and atherosclerosis.

journal_name

Atherosclerosis

journal_title

Atherosclerosis

authors

Trollope AF,Golledge J

doi

10.1016/j.atherosclerosis.2010.08.051

subject

Has Abstract

pub_date

2011-02-01 00:00:00

pages

237-43

issue

2

eissn

0021-9150

issn

1879-1484

pii

S0021-9150(10)00693-3

journal_volume

214

pub_type

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