Abstract：
:Serum phospholipids were analyzed for their content of long-chained fatty acids together with other components of lipoproteins (total- and HDL-cholesterol, apolipoproteins A-I and B, triglycerides), in 60 coronary heart disease patients and 30 control individuals. Some of the individual variations in content of the various components showed co-variation with each other. This formed the basis for the extraction of 7 'factors' by the statistical procedure 'factor analysis'. Analysis of variance was performed with the 'factor scores' for subgroups of high and low age and high and low total serum cholesterol. The analysis revealed two unexpected factors which discriminated with statistical significance between young, hypercholesterolaemic patients and controls. One factor was a positive risk factor and the other a negative one. They could possibly be dependent on the existence of two at present uncharacterized subgroups of lipoproteins. These lipoproteins contained, according to the analysis, large amounts of certain fatty acids. It is suggested that fatty acid analysis might be useful in the characterization of lipoproteins that are involved in the development of atherosclerosis.
journal_name
Atherosclerosisjournal_title
Atherosclerosisauthors
Aursnes I,Smith P,Christiansen EN,Berg Kdoi
10.1016/0021-9150(88)90017-2subject
Has Abstractpub_date
1988-02-01 00:00:00pages
219-24issue
2-3eissn
0021-9150issn
1879-1484pii
0021-9150(88)90017-2journal_volume
69pub_type
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