Localization of atherosclerotic lesions in the bifurcation of the main left coronary artery.

abstract：:This report concerns a heart transplant patient with hypercholesterolemia who showed rapid development of a severe transplant coronary artery disease. The patient received 10 mg pravastatine per day. Quantitative coronary angiography analyses of 4 serial angiograms clearly demonstrated that in the first 2.5 years foll...

journal_title：Atherosclerosis

authors： Park JW,Vermeltfoort M,Braun P,May E,Merz M

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:Matrix metalloproteinases (MMPs) have been implicated in development of atherosclerosis. MMPs are activated in patients with acute coronary syndrome (ACS). However, little data exist regarding the correlation between circulating levels of MMPs and plaque volume (PV) in patients with ACS. We therefore evaluat...

journal_title：Atherosclerosis

authors： Ogita M,Miyauchi K,Morimoto T,Daida H,Kimura T,Hiro T,Nakagawa Y,Yamagishi M,Ozaki Y,Matsuzaki M

更新日期：2013-01-01 00:00:00

abstract：:The insulin response to a standard oral glucose tolerance test (OGTT) and other anthropometric and biochemical risk factors for coronary heart disease (CHD) were measured in a random sample of 107 Edinburgh men, who were initially studied in 1976 when they were 40 and who were reexamined in 1988-89. Fasting glucose an...

journal_title：Atherosclerosis

authors： Hargreaves AD,Logan RL,Elton RA,Buchanan KD,Oliver MF,Riemersma RA

更新日期：1992-05-01 00:00:00

abstract：:Recent studies have clarified the significance of chemokines in cardiovascular diseases, such as development of atherosclerosis, atheromatous plaque rupture and restenosis after coronary angioplasty. We investigated changes in chemokine expression in the coronary circulation induced by percutaneous transluminal corona...

journal_title：Atherosclerosis

authors： Hojo Y,Ikeda U,Katsuki T,Mizuno O,Fukazawa H,Fujikawa H,Shimada K

更新日期：2001-05-01 00:00:00

abstract：OBJECTIVE:Recent studies have revealed that sequence variation on chromosome 9p21 is a major genetic determinant for coronary heart disease and stroke, however, the underlying mechanism remains unknown. This genomic region contains the gene encoding cyclin-dependent kinase 2A, a regulator of proliferation and different...

journal_title：Atherosclerosis

authors： Ye S,Willeit J,Xiao Q,Motterle A,Laxton RC,Oberhollenzer F,Kiechl S,Xu Q

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:To evaluate the impact of familial hypercholesterolemia (FH) and familial combined hyperlipidemia (FCH) on arterial properties and the effects of statins. METHODS:We meta-analyzed 51 studies providing data for 4,057 FH patients and 732 FCH patients with random-effects models, meta-regression analysis and pu...

journal_title：Atherosclerosis

authors： Masoura C,Pitsavos C,Aznaouridis K,Skoumas I,Vlachopoulos C,Stefanadis C

更新日期：2011-01-01 00:00:00

abstract：:Atherosclerosis is the most frequent complication of diabetes. There are many potentially atherogenic factors in diabetes that may underlie this problem. Of these, one is the group of dyslipoproteinemias. In diabetes there are both qualitative and quantitative changes in the plasma lipoproteins. Based on pathophysiolo...

journal_title：Atherosclerosis

authors： Steiner G

更新日期：1994-10-01 00:00:00

abstract：AIMS:We have examined the cross-sectional relationship between insulin resistance, the metabolic syndrome and haemostatic and inflammatory markers. METHODS AND RESULTS:We carried out the study in 2722 non-diabetic men aged 60-79 years with no history of coronary heart disease or stroke and who were not on warfarin tre...

journal_title：Atherosclerosis

authors： Wannamethee SG,Lowe GD,Shaper AG,Rumley A,Lennon L,Whincup PH

更新日期：2005-07-01 00:00:00

abstract：:Self-administration of anabolic-androgenic steroids to increase muscular strength and lean body mass has been used widely among athletes. Flow mediated dilatation (FMD) determined by ultrasound of the brachial artery is accepted as both an in vivo index of endothelial function and an indicator for future atheroscleros...

journal_title：Atherosclerosis

authors： Ebenbichler CF,Sturm W,Gänzer H,Bodner J,Mangweth B,Ritsch A,Sandhofer A,Lechleitner M,Föger B,Patsch JR

更新日期：2001-10-01 00:00:00

abstract：OBJECTIVE:The association of egg consumption with subclinical coronary atherosclerosis remains unknown. Our aim was to examine the association between egg consumption and prevalence of coronary artery calcium (CAC). METHODS:Cross-sectional study of 23,417 asymptomatic adult men and women without a history of cardiovas...

journal_title：Atherosclerosis

authors： Choi Y,Chang Y,Lee JE,Chun S,Cho J,Sung E,Suh BS,Rampal S,Zhao D,Zhang Y,Pastor-Barriuso R,Lima JA,Shin H,Ryu S,Guallar E

更新日期：2015-08-01 00:00:00

abstract：:We studied the aortic histology of 28 Macaca nigra males and females, from 6 to more than 20 years old, normal and manifesting various degrees of spontaneous diabetes. Correlations of several metabolic and hormonal indicators of diabetes severity with gross and microscopic findings in the aortas demonstrated direct as...

journal_title：Atherosclerosis

authors： Howard CF Jr,Vesselinovitch D,Wissler RW

更新日期：1984-07-01 00:00:00

abstract：:Dietary plant proteins may lower plasma cholesterol and LDL concentrations in hypercholesterolemic patients when substituted for animal proteins, particularly in diets with low cholesterol and saturated fat content. Plant protein diets appear, however, to be without effect on plasma lipoprotein levels in normal subjec...

journal_title：Atherosclerosis

authors： Meinertz H,Faergeman O,Nilausen K,Chapman MJ,Goldstein S,Laplaud PM

更新日期：1988-07-01 00:00:00

abstract：:In general, plasma concentrations of high density lipoproteins (HDL) are inversely related to the incidence of coronary artery disease. One exception to this trend is individuals with apolipoprotein A-I(Milano) (apo A-IM), a molecular variant of apo A-I, which results in very low plasma apo A-I and HDL-cholesterol lev...

journal_title：Atherosclerosis

authors： Chiesa G,Stoltzfus LJ,Michelagnoli S,Bielicki JK,Santi M,Forte TM,Sirtori CR,Franceschini G,Rubin EM

更新日期：1998-01-01 00:00:00

abstract：:Macrophage scavenger receptors class A (MSR) are thought to play an important role in atherogenesis by mediating the unrestricted uptake of modified lipoproteins by macrophages in the vessel wall leading to foam cell formation. To investigate the in vivo role of the MSR in this process, a transgenic mouse model expres...

journal_title：Atherosclerosis

authors： de Winther MP,van Dijk KW,van Vlijmen BJ,Gijbels MJ,Heus JJ,Wijers ER,van den Bos AC,Breuer M,Frants RR,Havekes LM,Hofker MH

更新日期：1999-12-01 00:00:00

abstract：:Increased aortic and liver prolyl hydroxylase activity has been suggested as an early biochemical indicator of the fibrotic changes which occur in rabbits with injury induced arteriosclerosis. Daily administration of epinephrine (0.025-0.050 mg/kg, i.v.) and thyroxine (0.050 mg/kg, i.p.) to rabbits for 3 weeks produce...

journal_title：Atherosclerosis

authors： Fuller GC,Matoney AL,Fisher DO,Fausto N,Cardinale GJ

更新日期：1976-09-01 00:00:00

abstract：:The pathogenesis of retinal vein occlusion (RVO), has not been well understood. Recent data have shown the efficacy of an anticoagulant therapy with LMWHs in the treatment of acute RVO suggesting the presence of a hypercoagulable state in these patients. New global tests for detection of hypercoagulability and hypofib...

journal_title：Atherosclerosis

authors： Cellai AP,Lami D,Fedi S,Marcucci R,Mannini L,Cenci C,Rogolino A,Sodi A,Menchini U,Abbate R,Prisco D

更新日期：2012-09-01 00:00:00

abstract：:Neutrophils have been implicated in ischaemic heart disease, unstable angina pectoris and acute myocardial infarction. Alterations in dietary levels of specific 18- and 20-carbon polyunsaturated fatty acids have significant clinical benefits in cardiovascular disease. However, to date there has been no concerted effor...

journal_title：Atherosclerosis

authors： Bates EJ,Ferrante A,Smithers L,Poulos A,Robinson BS

更新日期：1995-08-01 00:00:00

abstract：:In a random sample of 22 normolipidaemic male Caucasian individuals, 35-49 years old, homozygosity for the X2 allele (cutting site) of the XbaI RFLP of the apo B gene was associated with higher mean total cholesterol and LDL-cholesterol concentration. These individuals also had significantly lower LDL fractional catab...

journal_title：Atherosclerosis

authors： Houlston RS,Turner PR,Revill J,Lewis B,Humphries SE

更新日期：1988-05-01 00:00:00

abstract：BACKGROUND AND AIMS:Chronic intermittent hypoxia (CIH) exposure causes atherosclerosis, although the underlying mechanisms are poorly understood. This study defines the role of endothelial intrinsic NF-κB signaling in the atherogenic response to CIH. METHODS:We created ApoE-ECI-κBmt mice that are deficient in the apol...

journal_title：Atherosclerosis

authors： Song D,Fang G,Mao SZ,Ye X,Liu G,Miller EJ,Greenberg H,Liu SF

更新日期：2018-03-01 00:00:00

abstract：:Berberine, an alkaloid isolated from Chinese medicinal herbs, long been known for its anti-microbial activity and used to treat various infectious disorders in traditional Chinese medicine. In the present study, we have tested the hypothesis that berberine could inhibit vascular smooth muscle cell (VSMC) proliferation...

journal_title：Atherosclerosis

authors： Lee S,Lim HJ,Park HY,Lee KS,Park JH,Jang Y

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND AND AIMS:Parental history (PH) and genetic risk scores (GRSs) are separately associated with coronary heart disease (CHD), but evidence regarding their combined effects is lacking. We aimed to evaluate the joint associations and predictive ability of PH and GRSs for incident CHD. METHODS:Data for 4283 Cauca...

journal_title：Atherosclerosis

authors： Antiochos P,Marques-Vidal P,McDaid A,Waeber G,Vollenweider P

更新日期：2016-01-01 00:00:00

abstract：:Animal models are used extensively in the ongoing investigation of a possible causal link between Chlamydia pneumoniae infection and conditions such as asthma and cardiovascular disease. Respiratory infections have been studied in monkeys, while mouse and rabbit models have been used to study both respiratory and card...

journal_title：Atherosclerosis

authors： Saikku P,Laitinen K,Leinonen M

更新日期：1998-10-01 00:00:00

abstract：OBJECTIVE:Although C-reactive protein (CRP) and albuminuria are well-documented cardiovascular risk markers, the functional implications of these biomarkers and their combination on functional disability and metabolic risks in patients with cardiovascular disease (CVD) are unknown. METHODS:Data were from 1403 adults (...

journal_title：Atherosclerosis

authors： Kuo HK,Al Snih S,Kuo YF,Raji MA

更新日期：2012-06-01 00:00:00

abstract：:The present study focused on the role of blood flow in the formation of focal intimal hyperplasia in vein grafts, as well as the development of an engineering approach that can be used to eliminate disturbed blood flow and prevent blood flow-related focal intimal hyperplasia. A rat vein graft model was constructed by ...

journal_title：Atherosclerosis

authors： Liu SQ

更新日期：1998-10-01 00:00:00

abstract：:Atherosclerosis is an inflammatory disease characterised by increased expression of adhesion molecules for leukocytes on both the surface of dysfunctional endothelium and on smooth muscle cells (SMC) within the lesion. It is also characterised by altered SMC phenotypic expression, indicated by a decreased volume fract...

journal_title：Atherosclerosis

authors： Rolfe BE,Muddiman JD,Smith NJ,Campbell GR,Campbell JH

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Dietary long-chain (≥20 carbons) n-3 polyunsaturated fatty acids (PUFAs) reduce atherosclerosis and enhance macrophage autophagy activation. How macrophage autophagy impacts atherosclerotic progression, particularly when comparing dietary n-3 PUFA supplementation vs. saturated fat feeding, is unknow...

journal_title：Atherosclerosis

authors： Wang Z,Sequeira RC,Zabalawi M,Madenspacher J,Boudyguina E,Ou T,Nelson JM,Nie Y,Zhao Q,Fessler MB,Zhu X

更新日期：2020-02-01 00:00:00

abstract：:The fractional catabolic rate (FCR) for low density lipoprotein (LDL) apolipoprotein B (apo B) was studied to explore the variations in apo B as a possible cause of hypercholesterolemia. The FCR of radioiodine labelled autologous LDL and homologous LDL isolated from a normocholesterolemic subject were compared in fort...

journal_title：Atherosclerosis

authors： Korhonen T,Savolainen MJ,Kesäniemi YA

更新日期：1999-09-01 00:00:00

abstract：:The intravascular metabolism of cholesteryl [1-14C]oleoyl ester and [1,2-3H(N)]cholesteryl palmityl ether was compared in the rat, an animal species without plasma cholesteryl ester transfer activity (CETA). The tracers had identical plasma disappearance rates when they were incorporated into human or rat low density ...

journal_title：Atherosclerosis

authors： Terpstra AH

更新日期：1995-01-06 00:00:00

abstract：BACKGROUND AND AIMS:The beneficial effect of statin therapy has been well established for both primary and secondary prevention of cardiovascular disease. Nevertheless, it remains under-used among patients with chronic kidney disease (CKD). We aimed to investigate the impact of statin therapy across a wide spectrum of ...

journal_title：Atherosclerosis

authors： Natanzon SS,Matetzky S,Beigel R,Iakobishvili Z,Goldenberg I,Shechter M,Acute Coronary Syndrome Israel Survey (ACSIS) investigators.

更新日期：2019-07-01 00:00:00

abstract：:The purpose of this study was to determine the extent and sources of oxidative stress within skeletal muscle following an acute bout of contractile claudication. Twenty-four hours after unilateral ligation of the femoral artery, rat hind limbs were stimulated in vivo for 30 min, and force production measured. One-hour...

journal_title：Atherosclerosis

authors： Judge AR,Dodd SL

更新日期：2003-12-01 00:00:00