Detection of the terminal complement complex in patient plasma following acute myocardial infarction.

abstract：:The topography of atherosclerotic lesions in the human basilar arteries has been studied quantitatively by digitizing images of the excised vessels and producing contour probability maps. Fifteen basilar arteries were obtained at autopsy (age--61 +/- 2; males--6, females--9; black--6, white--9), fixed in formalin, ope...

journal_title：Atherosclerosis

authors： Cornhill JF,Akins D,Hutson M,Chandler AB

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Overt atherosclerotic cardiovascular disease (ASCVD) warrants aggressive lipid lowering. Imaging for ambiguous symptoms suggesting ischemia or for clarification of CV risk in asymptomatic individuals often uncovers previously unknown ASCVD. Guidelines do not provide clear recommendations for aggress...

journal_title：Atherosclerosis

authors： Mancini GBJ,Gupta M,Tsigoulis M,Cannon CP,Genest J,Ray KK,Santos RD,Watts GF,Raggi P

更新日期：2017-08-01 00:00:00

abstract：:Cardiovascular event reduction in hypercholesterolemic subjects appropriately emphasizes the prominent role of statin therapy; however, niacin (nicotinic acid) is also an effective lipid-altering agent that prevents atherosclerosis and reduces cardiovascular events. Niacin has multifarious lipoprotein and anti-atherot...

journal_title：Atherosclerosis

authors： Rosenson RS

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVE:Although many studies have reported that elevated serum triglycerides to high-density lipoprotein cholesterol (TG-HDL) ratios constitute a risk for insulin resistance and increased arterial stiffness, no study has clarified as yet the association, in terms of the TG-HDL ratio, between diabetes and increased a...

journal_title：Atherosclerosis

authors： Shimizu Y,Nakazato M,Sekita T,Kadota K,Yamasaki H,Takamura N,Aoyagi K,Maeda T

更新日期：2013-06-01 00:00:00

abstract：:Endothelium-derived relaxing and contracting factors play an important role in atherosclerosis, re-stenosis and graft survival. Internal thoracic artery (ITA) and saphenous vein (SV) are used as conduit vessels in coronary artery bypass graft surgery (CABG). The long-term graft patency rate is higher with ITA than SV....

journal_title：Atherosclerosis

authors： Hamilton CA,Berg G,Mcintyre M,Mcphaden AR,Reid JL,Dominiczak AF

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:Increasing studies have suggested that albuminuria might be an important risk factor for peripheral artery disease (PAD). However, studies focusing on the association between low-grade albuminuria and PAD are limited. It would be of great interest to elucidate the association between low-grade albuminuria an...

journal_title：Atherosclerosis

authors： Xu B,Dai M,Li M,Sun K,Zhang J,Wang T,Sun J,Chen Y,Xu M,Lu J,Bi Y

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Proteoglycan 4 (Prg4) has a high structural similarity with the established atherosclerosis-modulating proteoglycan versican, but its role in atherogenesis is still unknown. Therefore, the impact of Prg4 deficiency on macrophage function in vitro and atherosclerosis susceptibility in vivo was invest...

journal_title：Atherosclerosis

authors： Nahon JE,Hoekstra M,Havik SR,Van Santbrink PJ,Dallinga-Thie GM,Kuivenhoven JA,Geerling JJ,Van Eck M

更新日期：2018-07-01 00:00:00

abstract：:While statin treatment may transiently mobilize endothelial progenitor cells (EPCs), the dose-dependent effects of a continuous statin therapy on EPCs in patients with chronic coronary artery disease (CAD) have not been analyzed. In 209 patients with angiographically documented CAD, 144 of which received 10-40 mg/day ...

journal_title：Atherosclerosis

authors： Hristov M,Fach C,Becker C,Heussen N,Liehn EA,Blindt R,Hanrath P,Weber C

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Osteoporosis and coronary heart disease (CHD) are very common conditions among elderly people, and both represent a public health concern due to their prognostic consequences. Osteoporosis and CHD share many risk factors and pathophysiological mechanisms, such as calcification pathways. Clinical evi...

journal_title：Atherosclerosis

authors： Campos-Staffico AM,Freitas WM,Carvalho LSF,Coelho-Filho OR,Nadruz W Jr,Oliveira RB,Sposito AC,Brasilia Study on Healthy Aging and Brasilia Heart Study.

更新日期：2020-01-01 00:00:00

abstract：:Atherosclerosis is a complex disease that gene and environment interaction influences the progression of atherosclerotic lesion development. Our laboratory used mice lacking both the low density lipoprotein (LDL) receptor and Apobec1 genes (LDLR-/-Apobec1-/-, designated LDb) to investigate gene-gene interaction and th...

journal_title：Atherosclerosis

authors： Dutta R,Singh U,Li TB,Fornage M,Teng BB

更新日期：2003-07-01 00:00:00

abstract：:Fifty-seven sections of human vessels, collected in the Pathobiological Determinants of Atherosclerosis in Youth study from individuals aged 25-34, were stained with two monoclonal antibodies to oxidatively-modified lysine. Intensity and extent of immunoreactivity were graded by three pathologists. Aorta from a Watana...

journal_title：Atherosclerosis

authors： Sloop GD,Fallon KB,Lipscomb G,Takei H,Zieske A

更新日期：2000-02-01 00:00:00

abstract：:Prolonged exposure of rats to cigarette smoke resulted in significant alterations in the metabolism of lipids. There was a significant increase in the concentration of cholesterol, triglycerides and phospholipids in most of the tissues, particularly the heart, aorta and lungs. Cholesterol, triglycerides and phospholip...

journal_title：Atherosclerosis

authors： Latha MS,Vijayammal PL,Kurup PA

更新日期：1988-04-01 00:00:00

abstract：:There exists much evidence suggesting a major role for the oxidized low density lipoprotein (LDL) and VLDL particles in the pathogenesis of atherosclerosis. Although obesity is characterized by dyslipidemia, less is known about the oxidation capacity of lipoproteins in obese subjects. We measured the oxidizability in ...

journal_title：Atherosclerosis

authors： Van Gaal LF,Vertommen J,De Leeuw IH

更新日期：1998-04-01 00:00:00

abstract：OBJECTIVE:Only a few studies have investigated the changes in carotid intima-media thickness (IMT) over time, and uncertainties remain on the underlying mechanisms linking depression and subclinical atherosclerosis. We carried out a prospective cohort study to evaluate whether depression is associated with changes in c...

journal_title：Atherosclerosis

authors： Pizzi C,Costa GM,Santarella L,Flacco ME,Capasso L,Bert F,Manzoli L

更新日期：2014-04-01 00:00:00

abstract：:Colesevelam hydrochloride is a novel, potent, non-absorbed lipid-lowering agent previously shown to reduce low density lipoprotein (LDL) cholesterol. To examine the efficacy and safety of coadministration of colesevelam and atorvastatin, administration of these agents alone or in combination was examined in a double-b...

journal_title：Atherosclerosis

authors： Hunninghake D,Insull W Jr,Toth P,Davidson D,Donovan JM,Burke SK

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND AND AIMS:This study evaluated the effects of resveratrol on arterial aging and the renin-angiotensin system (RAS) in mice and vascular smooth muscle cells (VSMCs). METHODS:Aging mice were divided into control and resveratrol groups. Histological changes, inflammation, oxidative stress, RAS components, and t...

journal_title：Atherosclerosis

authors： Kim EN,Kim MY,Lim JH,Kim Y,Shin SJ,Park CW,Kim YS,Chang YS,Yoon HE,Choi BS

更新日期：2018-03-01 00:00:00

abstract：:The formation of atherosclerotic lesions requires the migration of vascular smooth muscle cells from the media into the intima of the artery and their proliferation. These events, which are preceded and accompanied by inflammation, are modulated by integrin receptors linking vascular smooth muscle cells to extracellul...

journal_title：Atherosclerosis

authors： Barillari G,Albonici L,Incerpi S,Bogetto L,Pistritto G,Volpi A,Ensoli B,Manzari V

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:In elderly patients traditional cardiovascular (CV) risk factors are poorly correlated with mortality and few data are available on determinants and consequences of supra-ventricular arrhythmia. In a cohort of 331 hospitalized elderly patients (mean age+/-SD=85+/-7 years), we assessed which CV characteristic...

journal_title：Atherosclerosis

authors： Vesin C,Protogerou AD,Lieber A,Safar H,Iaria P,Ducimetière P,Safar ME,Blacher J

更新日期：2009-12-01 00:00:00

abstract：:The heavy and light subfractions of low density lipoprotein (LDL) were bound to the same extent and with the same affinity by the LDL receptors of cultured human fibroblasts, both when assayed at 4 degrees C and when assayed at 37 degrees C. They were also degraded similarly by the low affinity, LDL-receptor-mediated ...

journal_title：Atherosclerosis

authors： Knight BL,Thompson GR,Soutar AK

更新日期：1986-03-01 00:00:00

abstract：:We evaluated a 69-year-old Japanese woman with apolipoprotein (apo) A-I deficiency, high levels of low-density lipoprotein (LDL)-cholesterol, hypertension and impaired glucose tolerance. The patient had corneal opacity, but neither xanthomas, xanthelasma, nor tonsillar hypertrophy. She was not symptomatic for coronary...

journal_title：Atherosclerosis

authors： Yokota H,Hashimoto Y,Okubo S,Yumoto M,Mashige F,Kawamura M,Kotani K,Usuki Y,Shimada S,Kitamura K,Nakahara K

更新日期：2002-06-01 00:00:00

abstract：:Fractional esterification rate of cholesterol in high density lipoprotein (HDL) (FER[HDL]) can predict the size distribution and physicochemical characteristics of HDL in plasma. In the present study, we investigated the correlation of FER(HDL) with the particle size of low density lipoprotein (LDL) (LDL-size) in 111 ...

journal_title：Atherosclerosis

authors： Ohta T,Saku K,Takata K,Nagata N,Maung KK,Matsuda I

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVE:Inflammatory factors modify the risk of cardiovascular diseases and atherosclerosis. The single base genetic polymorphism in the promoter region of inflammatory cytokine interleukin-6 (IL6 -174 G>C, rs1800795) is associated with the variation of IL-6 production. The aim of this study was to investigate whethe...

journal_title：Atherosclerosis

authors： Riikola A,Sipilä K,Kähönen M,Jula A,Nieminen MS,Moilanen L,Kesäniemi YA,Lehtimäki T,Hulkkonen J

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:The objective of the present study was to investigate the effects of one-year treatment with exenatide or Insulin Glargine, followed by a 5-week off-drug period, on postprandial lipidaemia, glycaemia and measures of oxidative stress. METHODS:Sixty-nine metformin-treated patients with type 2 diabetes were ran...

journal_title：Atherosclerosis

authors： Bunck MC,Cornér A,Eliasson B,Heine RJ,Shaginian RM,Wu Y,Yan P,Smith U,Yki-Järvinen H,Diamant M,Taskinen MR

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND AND AIMS:Whether carotid atherosclerosis is associated with an increased risk for ischemic stroke in patients with atrial fibrillation (AF) on anticoagulant treatment is undefined. To explore this association, patients with AF on treatment with vitamin K antagonists were included in a multicenter, prospectiv...

journal_title：Atherosclerosis

authors： Becattini C,Dentali F,Camporese G,Sembolini A,Rancan E,Tonello C,Manina G,Padayattil S,Agnelli G

更新日期：2018-04-01 00:00:00

abstract：:Endurance exercise training is known to produce favorable changes in the metabolic profile including reduced plasma triglyceride (TG) and increased high-density lipoprotein (HDL) cholesterol concentrations. These metabolic improvements are likely to contribute to the reduced coronary heart disease (CHD) risk often obs...

journal_title：Atherosclerosis

authors： Bergeron J,Couillard C,Després JP,Gagnon J,Leon AS,Rao DC,Skinner JS,Wilmore JH,Bouchard C

更新日期：2001-12-01 00:00:00

abstract：:Tissue plasminogen activator (tPA) is emerging as an important risk factor for coronary heart disease, but the association between tPA concentration and mortality in acute myocardial infarction (AMI) remains uncertain. We studied the relationship between tPA antigen level on admission and 30-day mortality in 226 conse...

journal_title：Atherosclerosis

authors： Lee CW,Ahn JM,Park DW,Kim YH,Hong MK,Song JK,Kim JJ,Park SW,Chi HS,Park SJ

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Oxidation of low-density lipoprotein (LDL) and oxidized LDL-mediated activation of the innate immune system have been recognized as early key events during the pathogenesis of atherosclerosis. Recent evidence identified eosinophils as a major source of enzymatic lipid oxidation and suggested a poten...

journal_title：Atherosclerosis

authors： Hofheinz K,Seibert F,Ackermann JA,Dietel B,Tauchi M,Oszvar-Kozma M,Kühn H,Schett G,Binder CJ,Krönke G

更新日期：2020-10-01 00:00:00

abstract：:The ATP-binding cassette transporter G1 (ABCG1) plays an important role in reverse cholesterol transport by exporting cholesterol to high density lipoproteins (HDL). Two major ABCG1 isoforms exist in humans, which differ by the presence or absence of twelve amino acids between the ATP cassette and the transmembrane do...

journal_title：Atherosclerosis

authors： Burns V,Sharpe LJ,Gelissen IC,Brown AJ

更新日期：2013-02-01 00:00:00

abstract：:Cholesteryl ester transfer from solid-phase bound HDL to endogenous plasma HDL or VLDL/LDL was determined in 50 patients with primary disorders of lipid metabolism and 27 normolipidemic subjects. Transfer to the plasma HDL pool was significantly reduced in familial hypercholesterolemia, familial combined hyperlipidemi...

journal_title：Atherosclerosis

authors： Sparks DL,Frohlich J,Lacko AG,Pritchard PH

更新日期：1989-06-01 00:00:00

abstract：OBJECTIVES:We examined the associations between HbA1c levels and various atherosclerotic vascular parameters among adults without diabetes from the general population. METHODS:A total of 6500 community-dwelling adults, who were free of type 2 diabetes and ≥50 years of age, were included. High-resolution B-mode ultraso...

journal_title：Atherosclerosis

authors： Lee YH,Shin MH,Choi JS,Rhee JA,Nam HS,Jeong SK,Park KS,Ryu SY,Choi SW,Kim BH,Oh GJ,Kweon SS

更新日期：2016-04-01 00:00:00