Effect of exposure of rats to cigarette smoke on the metabolism of lipids.

abstract：:Connective tissue growth factor (CTGF) is expressed in atherosclerotic plaques. It is generally recognized that CTGF contributes to atherosclerosis by stimulating vascular smooth muscle cell (VSMC) proliferation and extracellular matrix production during the development of atherosclerosis. Recent studies indicate that...

journal_title：Atherosclerosis

authors： Game BA,He L,Jarido V,Nareika A,Jaffa AA,Lopes-Virella MF,Huang Y

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND AND AIMS:Overt atherosclerotic cardiovascular disease (ASCVD) warrants aggressive lipid lowering. Imaging for ambiguous symptoms suggesting ischemia or for clarification of CV risk in asymptomatic individuals often uncovers previously unknown ASCVD. Guidelines do not provide clear recommendations for aggress...

journal_title：Atherosclerosis

authors： Mancini GBJ,Gupta M,Tsigoulis M,Cannon CP,Genest J,Ray KK,Santos RD,Watts GF,Raggi P

更新日期：2017-08-01 00:00:00

abstract：:Hypercholesterolemia impairs endothelial function. However, the production/release of nitric oxide from the hypercholesterolemic aorta is reported to be enhanced rather than impaired in animal studies. L-arginine improves endothelial function in hypercholesterolemic subjects. The goal of the present study was to inves...

journal_title：Atherosclerosis

authors： Kawano H,Motoyama T,Hirai N,Kugiyama K,Yasue H,Ogawa H

更新日期：2002-04-01 00:00:00

abstract：:The serum concentrations of testosterone, androstenedione, oestradiol and total low polar oestrogens, mainly oestradiol and oestrone, were measured in 26 healthy male subjects. The subjects were divided into two groups each of them with low (less than 1.04 mmol/l) and high (greater than 1.56 mmol/l) levels of serum HD...

journal_title：Atherosclerosis

authors： Nordøy A,Aakvaag A,Thelle D

更新日期：1979-12-01 00:00:00

abstract：:Apolipoprotein (apo) E is a multifunctional protein that can act as a ligand for lipoprotein receptors. The receptor-mediated clearance of the triglyceride-rich lipoproteins (TRL) chylomicrons and VLDL from plasma is, in part, dependent on apo E. Enrichment of VLDL with apo E is thought to enhance receptor-mediated cl...

journal_title：Atherosclerosis

authors： Millar JS,Lichtenstein AH,Ordovas JM,Dolnikowski GG,Schaefer EJ

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:Tissue proportions of long chain n-6 [especially arachidonic acid (AA)] and n-3 fatty acids [FA; eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) acids], or some ratio of these may be markers of risk for coronary heart disease (CHD). The purpose of this paper is to evaluate the published associatio...

journal_title：Atherosclerosis

authors： Harris WS,Poston WC,Haddock CK

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND AND AIMS:Oxidation of low-density lipoprotein (LDL) and oxidized LDL-mediated activation of the innate immune system have been recognized as early key events during the pathogenesis of atherosclerosis. Recent evidence identified eosinophils as a major source of enzymatic lipid oxidation and suggested a poten...

journal_title：Atherosclerosis

authors： Hofheinz K,Seibert F,Ackermann JA,Dietel B,Tauchi M,Oszvar-Kozma M,Kühn H,Schett G,Binder CJ,Krönke G

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:Periostin is dramatically upregulated in rat carotid arteries after balloon injury. The objective of the present study was to understand mechanisms underlying periostin upregulation in balloon-injured rat carotid arteries and in cultured vascular smooth muscle cells (VSMCs). METHODS AND RESULTS:Periostin pro...

journal_title：Atherosclerosis

authors： Li G,Oparil S,Sanders JM,Zhang L,Dai M,Chen LB,Conway SJ,McNamara CA,Sarembock IJ

更新日期：2006-10-01 00:00:00

abstract：AIMS:We determined the 6-year incidence of peripheral arterial disease (PAD) in a French population and assessed the association of glucose metabolism, smoking, cardiovascular risk factors and physical activity with incident PAD. METHODS:Participants from the French Data from a Epidemiological Study on the Insulin Res...

journal_title：Atherosclerosis

authors： Tapp RJ,Balkau B,Shaw JE,Valensi P,Cailleau M,Eschwege E,DESIR Study Group.

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:CD36 signal transductions have been reported by a variety of lipid moiety of oxidized low-density lipoprotein (oxLDL), however, CD36 signal induced by 7-ketocholesteryl-9-carboxynonanoate (oxLig-1), a lipid moiety of oxLDL has not been elucidated. METHODS AND RESULTS:OxLig-1 leads to activation and recruitm...

journal_title：Atherosclerosis

authors： Li W,Wang D,Chi Y,Wang R,Zhang F,Ma G,Chen Z,Li J,Liu Z,Matsuura E,Liu Q

更新日期：2013-01-01 00:00:00

abstract：:Factor XIII is a transglutaminase that crosslinks fibrin in the last steps of the coagulation process. A few polymorphic sites have been identified in this gene, one of them being a point mutation (FXIII Val34Leu), leading to an amino acid change of valine to leucine. Recently, in British patients, FXIII 34Leu allele ...

journal_title：Atherosclerosis

authors： Wartiovaara U,Perola M,Mikkola H,Tötterman K,Savolainen V,Penttilä A,Grant PJ,Tikkanen MJ,Vartiainen E,Karhunen PJ,Peltonen L,Palotie A

更新日期：1999-02-01 00:00:00

abstract：:We have used DNA and protein polymorphisms for the third complement component (C3) to assess the potential of DNA markers in the diagnosis and study of familial hypercholesterolaemia (FH), and to confirm the reported linkage between FH and C3. The inheritance of FH and the C3 gene has been studied in 10 families by co...

journal_title：Atherosclerosis

authors： Humphries SE,Donald JA,McFadden JJ,Shull S,Williamson R,Jowett NI,Galton DJ,Julsrud JO,Berg K,Heiberg A

更新日期：1984-09-01 00:00:00

abstract：:The aim of this study was to examine whether the well-established effect of the common TaqIB polymorphism in intron 1 of the gene for cholesterol ester transfer protein (CETP) on high density lipoprotein cholesterol (HDL-C) concentration and increased risk of myocardial infarction (MI), could be explained by the recen...

journal_title：Atherosclerosis

authors： Eiriksdottir G,Bolla MK,Thorsson B,Sigurdsson G,Humphries SE,Gudnason V

更新日期：2001-11-01 00:00:00

abstract：:To elucidate the associations between Lp(a) levels and coronary and aortic atherosclerosis, we performed aortic MRI in 143 patients undergoing coronary angiography. Severity of aortic atherosclerosis was represented as plaque scores. Of the 143 patients, 104 had coronary artery disease (CAD). Thoracic and abdominal ao...

journal_title：Atherosclerosis

authors： Momiyama Y,Ohmori R,Fayad ZA,Tanaka N,Kato R,Taniguchi H,Nagata M,Ohsuzu F

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Fenofibrate, a PPAR-α agonist and rosiglitazone, a PPAR-γ agonist, reduce triglycerides and fatty acids in humans and in animal disease models. The efficacy of PPAR-α agonists in mouse model of human atherosclerosis disease has shown mixed results, and efficacy of PPAR-γ and liver X receptor (LXR) agonists h...

journal_title：Atherosclerosis

authors： Srivastava RA

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVES:We conducted a meta-analysis of relevant randomized trials to assess whether folic acid supplementation reduces the progression of atherosclerosis as measured by carotid intima-media thickness (CIMT). METHODS:This analysis included 2052 subjects from ten folic acid randomized trials with the change in CIMT ...

journal_title：Atherosclerosis

authors： Qin X,Xu M,Zhang Y,Li J,Xu X,Wang X,Xu X,Huo Y

更新日期：2012-06-01 00:00:00

abstract：INTRODUCTION:Cardio- and/or cerebro-vascular risk are associated with high lipoprotein (a) [Lp(a)] levels and low-molecular-weight (LMW) apo(a) isoforms. Aims of this study were to evaluate the deposition of apo(a) isoforms and apoprotein B (apo B) in atherosclerotic plaque from patients (males and females) who had car...

journal_title：Atherosclerosis

authors： Baldo G,Giunco S,Kontothanassis D,Baiocchi MR,Valerio A,Frego M

更新日期：2007-07-01 00:00:00

abstract：:In monocyte-derived macrophages from both normal and familial hypercholesterolaemic (FH) subjects, degradation of low density lipoprotein (LDL) through non-saturable pathways produced the same fall in 3-hydroxy-3-methylglutaryl-CoA reductase activity as receptor-mediated degradation of acetylated LDL, yet did not lead...

journal_title：Atherosclerosis

authors： Knight BL,Soutar AK,Patel DD

更新日期：1987-04-01 00:00:00

abstract：:The chemokines are a family of signalling proteins that participate in regulation of the immune system and have been implicated in the pathogenesis of vascular diseases. Deleting the gene encoding the chemokine MCP-1 in mouse models of atherosclerosis reduces lipid lesion formation and circulating chemokines are upreg...

journal_title：Atherosclerosis

authors： Mosedale DE,Smith DJ,Aitken S,Schofield PM,Clarke SC,McNab D,Goddard H,Gale CR,Martyn CN,Bethell HW,Barnard C,Hayns S,Nugent C,Panicker A,Grainger DJ

更新日期：2005-12-01 00:00:00

abstract：:High serum concentrations of soluble adhesion molecules are present in diabetics, but whether similar levels are present in patients with impaired glucose tolerance (IGT) is unclear. We measured serum concentrations of soluble intercellular adhesion molecule-1 (sICAM-1), vascular cell adhesion molecule-1 (sVCAM-1), an...

journal_title：Atherosclerosis

authors： Matsumoto K,Miyake S,Yano M,Ueki Y,Tominaga Y

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:Soluble intercellular adhesion molecule-1 (sICAM-1) is a transmembrane protein involved in the migration and adhesion of leukocytes to the vascular endothelium. While some studies indicate that elevated baseline sICAM-1 levels predict cardiovascular events, most of these studies were done in men; moreover, u...

journal_title：Atherosclerosis

authors： Albert MA,Glynn RJ,Buring JE,Ridker PM

更新日期：2008-03-01 00:00:00

abstract：:Highly active antiretroviral therapy (HAART) has greatly extended the lives of people infected with the human immunodeficiency virus (HIV). This reduced risk of early death from opportunistic infections or other sequelae of HIV infection, however, means that other possible causes of death emerge. Myocardial infarction...

journal_title：Atherosclerosis

authors： Fisher SD,Miller TL,Lipshultz SE

更新日期：2006-03-01 00:00:00

abstract：:The purpose of the present study was to examine the relationship between the changes in the expressions of several mRNAs and changes in endothelial function in streptozotocin-induced diabetic and chronic short-term insulin-treated rats. Aortas from later-stage (10 week) diabetics, but not those from their insulin-trea...

journal_title：Atherosclerosis

authors： Kobayashi T,Oishi K,Hayashi Y,Matsumoto T,Kamata K

更新日期：2006-03-01 00:00:00

abstract：:Selected normal human arteries and veins were solubilized with detergents, neutral salt buffers and organic solvents. Comparative sodium dodecyl sulphate polyacrylamide gels and thin layer chromatographic plates were developed and the patterns compared. The low molecular weight periodic acid--Schiff positive band seen...

journal_title：Atherosclerosis

authors： Moore CR,Gilbert DB

更新日期：1980-03-01 00:00:00

abstract：:Serum total and HDL cholesterol concentrations were measured in schoolboy populations from 16 countries. Total and HDL cholesterol concentrations were determined in one laboratory to reduce methodological variability as much as possible. A standardized protocol was used for the drawing of blood, preparation, storage a...

journal_title：Atherosclerosis

authors： Knuiman JT,Hermus RJ,Hautvast JG

更新日期：1980-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Dysregulation of long non-coding RNAs (lncRNAs) has been proven to be involved in the pathogenesis of coronary artery disease (CAD). However, it remains to be extensively explored. Thus, the present study aims to study expression patterns, biological functions, and diagnostic value of lncRNAs in CAD...

journal_title：Atherosclerosis

authors： Li L,Wang L,Li H,Han X,Chen S,Yang B,Hu Z,Zhu H,Cai C,Chen J,Li X,Huang J,Gu D

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVES:Adipocyte fatty acid-binding protein (A-FABP) has been shown to have an effect on insulin resistance, lipid metabolism, and atherosclerosis in animals. We therefore investigated the association between the serum A-FABP level and coronary atherosclerosis. METHODS:One hundred twenty-five consecutive patients ...

journal_title：Atherosclerosis

authors： Miyoshi T,Onoue G,Hirohata A,Hirohata S,Usui S,Hina K,Kawamura H,Doi M,Kusano KF,Kusachi S,Ninomiya Y

更新日期：2010-07-01 00:00:00

abstract：:The effect of different fat loads on postprandial lipemia and hemostatic activity was examined in 10 middle-aged men using 3 different meals. One meal was rich in saturated fatty acids (cream), the other rich in n-6 polyunsaturated fatty acids (sunflower oil) and the third was fat-free containing only carbohydrates. L...

journal_title：Atherosclerosis

authors： Salomaa V,Rasi V,Pekkanen J,Jauhiainen M,Vahtera E,Pietinen P,Korhonen H,Kuulasmaa K,Ehnholm C

更新日期：1993-10-01 00:00:00

abstract：OBJECTIVE:Diabetes and atherosclerosis may share common genetic determinants. A prior study in Hispanics found association of haplotypes in the diabetes gene calpain-10 (CAPN10) with carotid artery intima-media thickness (CIMT). This study sought to replicate this association in an independent cohort. METHODS:Four CAP...

journal_title：Atherosclerosis

authors： Goodarzi MO,Taylor KD,Jones MR,Fang B,Guo X,Xiang AH,Buchanan TA,Hodis HN,Raffel LJ,Rotter JI

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:How 9p21 variation affects risk of cardiovascular disease is unclear, so we assessed whether 9p21 variants are associated with arterial elasticity or retinal microvascular findings. METHODS:In the prospective Multi-Ethnic Study of Atherosclerosis (MESA) we assessed 378 SNPs in the 9p21 locus. Within four eth...

journal_title：Atherosclerosis

authors： Folsom AR,Pankow JS,Li X,Duprez DA,Jacobs DR Jr,Klein R,Klein B,Tang W,Wong TY,Cotch MF,Taylor KD,Rich SS,Hall JL,Post WS,Rotter JI

更新日期：2013-10-01 00:00:00