Changes in aortic endothelial gene expressions and relaxation responses following chronic short-term insulin treatment in diabetic rats.

abstract：OBJECTIVE:In this study, we compared the changes in arterial stiffness in chronic hemodialysis patients treated with 8-h vs. 4-h thrice weekly in-center hemodialysis. METHODS:Sixty prevalent chronic hemodialysis patients assigned to 8-h nocturnal in-center thrice weekly HD (NHD) and 60 control cases assigned to 4-h th...

journal_title：Atherosclerosis

authors： Demirci MS,Celik G,Ozkahya M,Tumuklu M,Toz H,Asci G,Duman S,Basci A,Kircelli F,Ozdogan O,Demirci C,Can L,Isik IO,Ok E,Long Dialysis Group.

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Lipoprotein(a) (Lp(a)) is a causal risk factor for cardiovascular disorders including coronary heart disease and calcific aortic valve stenosis. Apolipoprotein(a) (apo(a)), the unique glycoprotein component of Lp(a), contains sequences homologous to plasminogen. Plasminogen activation is markedly ac...

journal_title：Atherosclerosis

authors： Romagnuolo R,Scipione CA,Bazzi ZA,Boffa MB,Koschinsky ML

更新日期：2018-08-01 00:00:00

abstract：:Serum lipids, lipoproteins and Achilles tendon thickness in 52 patients with heterozygous familial hypercholesterolemia (FH) were investigated in order to clarify what are the important factors for the development of coronary artery disease (CAD) in heterozygous FH patients. There were no significant differences in th...

journal_title：Atherosclerosis

authors： Hirobe K,Matsuzawa Y,Ishikawa K,Tarui S,Yamamoto A,Nambu S,Fujimoto K

更新日期：1982-08-01 00:00:00

abstract：OBJECTIVE:Diabetes and atherosclerosis may share common genetic determinants. A prior study in Hispanics found association of haplotypes in the diabetes gene calpain-10 (CAPN10) with carotid artery intima-media thickness (CIMT). This study sought to replicate this association in an independent cohort. METHODS:Four CAP...

journal_title：Atherosclerosis

authors： Goodarzi MO,Taylor KD,Jones MR,Fang B,Guo X,Xiang AH,Buchanan TA,Hodis HN,Raffel LJ,Rotter JI

更新日期：2009-08-01 00:00:00

abstract：:The effect of the apolipoprotein C-II/C-III1 ratio on the capacity of purified bovine milk lipoprotein lipase to hydrolyse triglycerides was measured in a controlled model of pyrene-labeled nonanoyltriglycerides (1-2 ditetradecyl 3-pyrene nonanoyl glyceride) monolayer vesicles. Monolayer was composed of triglycerides,...

journal_title：Atherosclerosis

authors： Lambert DA,Catapano AL,Smith LC,Sparrow JT,Gotto AM Jr

更新日期：1996-12-20 00:00:00

abstract：:Marked hypercholesterolemia and moderate lipid infiltration of the aorta were induced by feeding rabbits a diet containing 1% cholesterol + 3% corn oil for 70 days. In the liver the concentration and pool size of cholesterol increased and those of triglycerides (TG) decreased. On dietary addition of vitamin A and vita...

journal_title：Atherosclerosis

authors： Brattsand R

更新日期：1975-07-01 00:00:00

abstract：BACKGROUND AND AIMS:The optimal approaches to management of patients treated with moderate statin doses on lipid parameters are unknown. The ACCENTUATE study aimed to compare the effects of adding the cholesteryl ester transfer protein inhibitor (CETP) evacetrapib, ezetimibe or increasing statin dose in atorvastatin-tr...

journal_title：Atherosclerosis

authors： Nicholls SJ,Ray KK,Ballantyne CM,Beacham LA,Miller DL,Ruotolo G,Nissen SE,Riesmeyer JS,ACCENTUATE Investigators.

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Familial hypercholesterolaemia (FH) is a powerful risk factor for cardiovascular (CV) events. High levels of low-density lipoprotein cholesterol (LDL-C) since birth are linked to the early onset of atherosclerotic disease. A genetic mutation determining FH is present in about one subject out of 250;...

journal_title：Atherosclerosis

authors： Gulizia MM,Maggioni AP,Abrignani MG,Bilato C,Mangiacapra F,Sanchez FA,Piovaccari G,Montagna L,Marini M,De Biasio M,Averna M,Casula M,Colivicchi F,Fabbri G,Lucci D,Zampoleri V,Catapano AL,POSTER Investigators.

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:Carotid intima-media thickness (IMT) is a measure of arterial thickening and a risk predictor for myocardial infarction and stroke. It is unclear whether IMT also predicts atrial fibrillation (AF). We explored the association between IMT and incidence of first AF hospitalization in a population-based cohort. ...

journal_title：Atherosclerosis

authors： Adamsson Eryd S,Östling G,Rosvall M,Persson M,Smith JG,Melander O,Hedblad B,Engström G

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:High homocysteine level is a risk factor for atherosclerosis and has been associated with lacunar infarcts (LIs), white matter lesions (WML) and cognitive dysfunction. It is unclear whether homocysteine is associated with cerebral small vessel disease (cSVD) on top of pre-existent atherosclerosis. We evaluate...

journal_title：Atherosclerosis

authors： Kloppenborg RP,Nederkoorn PJ,van der Graaf Y,Geerlings MI

更新日期：2011-06-01 00:00:00

abstract：INTRODUCTION:Although cardiovascular events are known to cluster in families it is unclear the extent to which atherosclerosis per se is genetically determined. The aim of this study was to assess the heritability of carotid intima media thickness (IMT) measurements, a surrogate marker of early atherosclerosis, using a...

journal_title：Atherosclerosis

authors： Swan L,Birnie DH,Inglis G,Connell JM,Hillis WS

更新日期：2003-01-01 00:00:00

abstract：:HMG-CoA reductase inhibitors have been shown to be effective in primary and secondary prevention of coronary heart disease. Their mechanism of action is attributed to their cholesterol lowering activity but recent results seem to indicate additional effects related to the modulation of other processes that regulate th...

journal_title：Atherosclerosis

authors： Alfon J,Guasch JF,Berrozpe M,Badimon L

更新日期：1999-08-01 00:00:00

abstract：:We tested whether low high-density lipoprotein cholesterol (HDL-C) and/or high triglycerides are associated to abnormal HDL subclasses distribution and composition, and their relationships with fasting insulin and C-reactive protein (CRP). Four groups of adolescents were studied: group 1 (HDL-C< or =35 mg/dl+TG> or =1...

journal_title：Atherosclerosis

authors： Medina-Urrutia A,Juarez-Rojas JG,Martínez-Alvarado R,Jorge-Galarza E,Posadas-Sánchez R,Cardoso-Saldaña G,Caracas-Portilla N,Mendoza-Perez E,Posadas-Romero C

更新日期：2008-12-01 00:00:00

abstract：:Baroreceptor sensitivity was studied in twelve young normotensive subjects and forty hypertensive patients, separated into two groups according to their age, severity of hypertension and signs of severe atherosclerotic vascular disease. Under stabilized circulatory conditions, the changes of pulse rate in response to ...

journal_title：Atherosclerosis

authors： Vlachakis ND,Mendlowitz M,DGuia D,DGusman D

更新日期：1976-07-01 00:00:00

abstract：AIMS:Apolipoprotein C-III (apoC-III) has been recognized as a useful marker of triglyceride-rich lipoproteins (TRLs) metabolism and proposed as an indicator of prognosis for coronary risk in healthy subjects. We studied cross-sectionally in a population having low cholesterol levels, but a high prevalence of the metabo...

journal_title：Atherosclerosis

authors： Onat A,Hergenç G,Sansoy V,Fobker M,Ceyhan K,Toprak S,Assmann G

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:The complement system is involved in the pathogenic course of SLE. These patients exhibit metabolic disturbances in lipoprotein metabolism characterized by a pro-inflammatory status and an accelerated atherosclerosis. The aim of this study is to investigate whether levels of the complement are associated to ...

journal_title：Atherosclerosis

authors： Parra S,Vives G,Ferré R,González M,Guardiola M,Ribalta J,Castro A

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:Genetic variation in CC-chemokine receptor-2 (CCR2) and -5 (CCR5), and their common haplotypes, acting through inflammatory responses, may affect atherosclerosis and risk of coronary heart disease (CHD). METHOD AND RESULTS:We examined seven common variants in the CCR2 and CCR5 loci and risk of CHD among wome...

journal_title：Atherosclerosis

authors： Pai JK,Kraft P,Cannuscio CC,Manson JE,Rexrode KM,Albert CM,Hunter D,Rimm EB

更新日期：2006-05-01 00:00:00

abstract：:Primary Biliary Cirrhosis (PBC) is a chronic, progressive liver disease associated with markedly elevated serum lipids, but it is not clear if PBC is associated with accelerated atherosclerosis. The present systematic review examined the relationship of PBC to atherosclerotic risk. The lipid abnormalities in PBC are c...

journal_title：Atherosclerosis

authors： Sorokin A,Brown JL,Thompson PD

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Familial hypercholesterolemia (FH) is a common inherited disorder of low density lipoprotein-cholesterol (LDL-C) metabolism. It is associated with higher risk of premature coronary heart disease. Around 60% of patients with a clinical diagnosis of FH do not have a detectable mutation in the genes ca...

journal_title：Atherosclerosis

authors： Sharifi M,Higginson E,Bos S,Gallivan A,Harvey D,Li KW,Abeysekera A,Haddon A,Ashby H,Shipman KE,Cooper JA,Futema M,Roeters van Lennep JE,Sijbrands EJG,Labib M,Nair D,Humphries SE

更新日期：2017-08-01 00:00:00

abstract：:The metabolism in vitro of exogenous and endogenous arachidonic acid was studied in circulating blood monocytes obtained from control (control group) and cholesterol (0.5%)-fed (cholesterol group) rabbits. The production of superoxide anion (O2-), tissue plasminogen activator (t-PA) and adherence of monocytes were ass...

journal_title：Atherosclerosis

authors： Saito H,Salmon JA,Moncada S

更新日期：1986-08-01 00:00:00

abstract：:Atherosclerosis causing cardiovascular disease is the most common cause of death in the developed world. Early precursors of vascular changes - subclinical atherosclerosis - warrant special attention as this process can be stabilized or even reversed if treated in time. Sonographic Intima Media Thickness measurement o...

journal_title：Atherosclerosis

authors： Dalla Pozza R,Ehringer-Schetitska D,Fritsch P,Jokinen E,Petropoulos A,Oberhoffer R,Association for European Paediatric Cardiology Working Group Cardiovascular Prevention.

更新日期：2015-02-01 00:00:00

abstract：:We have analyzed the development of aortic and coronary atherosclerosis over 40 years in native and non-native males of Yakutsk by comparing the data obtained in 1963-1965, 1985-1987 and 2001-2003. The research was carried out in compliance with the WHO program for the atherosclerosis epidemiology studies using autops...

journal_title：Atherosclerosis

authors： Zhdanov VS,Sternby NH,Voronova OV,Galakhov IE,Argunov VA

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVE:Genomewide association studies (GWAS), conventional association studies and the characterization of families with ApoA5 deficiency have shown that variation in the apolipoprotein A5 (APOA5) gene is associated with plasma triglyceride levels. The aim of this study was to determine the frequency of rare variant...

journal_title：Atherosclerosis

authors： Evans D,Aberle J,Beil FU

更新日期：2011-12-01 00:00:00

abstract：:We have examined the prevalence of clinically significant atherosclerosis in 78 patients with type III hyperlipoproteinemia (HLP) and homozygosity for apolipoprotein (apo) E2. Forty-six of these individuals (59%) had no atherosclerosis, 32 patients (41%) had atherosclerosis, i.e., atherosclerosis of the extracranial c...

journal_title：Atherosclerosis

authors： Dobmeyer J,Lohrmann J,Feussner G

更新日期：1996-01-05 00:00:00

abstract：OBJECTIVE:To investigate the statin eligibility and the predictabilities for cardiovascular disease between AHA/ACC and ATPIII guidelines, comparing those results to concomitant coronary artery calcium scores (CACS) in a large cohort of Korean individuals who met statin-eligibility criteria. METHODS:Among 19,920 parti...

journal_title：Atherosclerosis

authors： Rhee EJ,Park SE,Oh HG,Park CY,Oh KW,Park SW,Blankstein R,Plutzky J,Lee WY

更新日期：2015-05-01 00:00:00

abstract：:The effect of prostaglandins (PG) on initiation of DNA synthesis in arterial smooth muscle cells (SMC) stimulated with platelet-derived growth factor (PDGF) was examined. A concentration of 10 ng/ml PGE1 inhibited DNA synthesis, measured as autoradiographically labeled nuclei, by about 70%. Similar results were obtain...

journal_title：Atherosclerosis

authors： Nilsson J,Olsson AG

更新日期：1984-10-01 00:00:00

abstract：:This study sought to examine the association between cigarette smoking and serum bilirubin antioxidant concentrations in 715 middle-aged men undergoing coronary angiography. The study involved 153 current smokers, 251 who quit smoking and 311 who never smoked. Serum bilirubin concentrations were divided into the follo...

journal_title：Atherosclerosis

authors： Schwertner HA

更新日期：1998-02-01 00:00:00

abstract：:Vascular endothelial cell death contributes to the progression of atherosclerotic lesion, and several transcriptional regulators are involved in the process. Activating transcription factor 3/liver regenerating factor-1 (ATF3/LRF-1), a stress-inducible transcriptional repressor, was shown to be highly expressed in vas...

journal_title：Atherosclerosis

authors： Nawa T,Nawa MT,Adachi MT,Uchimura I,Shimokawa R,Fujisawa K,Tanaka A,Numano F,Kitajima S

更新日期：2002-04-01 00:00:00

abstract：:A total of ten healthy elderly subjects ingested one capsule of 600 mg (corresponding to 150 mg docosahexaenoic acid and 30 mg eicosapentaenoic acid) RO-PUFA triglycerides per day and ten others ingested one capsule of 600 mg sunflower oil as a placebo for 42 days. In the n-3 polyunsaturated fatty acids (PUFA) group, ...

journal_title：Atherosclerosis

authors： Véricel E,Calzada C,Chapuy P,Lagarde M

更新日期：1999-11-01 00:00:00

abstract：:The lifetime cardiovascular risk of a diabetic patient is approximately 4-5 times higher than that of an age and sex matched individual without diabetes mellitus. Despite the well-publicized cardiovascular risk equivalence of diabetes mellitus, it has become apparent that not all diabetic patients are equally at high-...

journal_title：Atherosclerosis

authors： Raggi P

更新日期：2018-04-01 00:00:00