Replication of calpain-10 genetic association with carotid intima-media thickness.

abstract：:Epidemiological and clinical data demonstrate differences in atherosclerotic coronary heart disease prevalence between age-matched men and premenopausal women. Mechanisms underlying relative athero-susceptibility in men and athero-resistance in premenopausal women remain to be elucidated. Lack of informative animal mo...

journal_title：Atherosclerosis

authors： Herrera VL,Tsikoudakis A,Didishvili T,Ponce LR,Bagamasbad P,Gantz D,Herscovitz H,Van Tol A,Ruiz-Opazo N

更新日期：2004-11-01 00:00:00

abstract：:We determined the effects of different dialysis conditions on the antioxidant content, duration of the lag phase and oxidation rate of LDL. Dialysis for 22 h resulted in a 56%--66% reduction in the concentrations of beta-carotene, lycopene and alpha-tocopherol. The lag phase of copper-induced oxidation of freshly isol...

journal_title：Atherosclerosis

authors： Scheek LM,Wiseman SA,Tijburg LB,van Tol A

更新日期：1995-09-01 00:00:00

abstract：AIMS:To assess efficacy and safety of HMG-CoA reductase inhibitor (statin) treatment in children and adolescents with heterozygous familial hypercholesterolaemia. METHODS:MEDLINE, EMBASE, COCHRANE and Current Controlled Trials databases were searched. Study design, efficacy, and safety outcome-measures were extracted....

journal_title：Atherosclerosis

authors： Arambepola C,Farmer AJ,Perera R,Neil HA

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVE:The utility of lipoprotein particle profiles measured by nuclear magnetic resonance (NMR) spectroscopy beyond standard serum lipids remains inconclusive. Furthermore, few studies have compared NMR measurements with standard lipids in association with coronary artery calcification (CAC) in Japanese, where the ...

journal_title：Atherosclerosis

authors： Hisamatsu T,Fujiyoshi A,Miura K,Ohkubo T,Kadota A,Kadowaki S,Kadowaki T,Yamamoto T,Miyagawa N,Zaid M,Torii S,Takashima N,Murakami Y,Okamura T,Horie M,Ueshima H,SESSA Research Group.

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVES:Compare carotid plaque morphology of acute symptomatic, recently symptomatic and asymptomatic patients (groups 1, 2 and 3 respectively) with carotid artery disease using high resolution magnetic resonance imaging (MRI), to identify high-risk plaque characteristics best associated with risk of recurrent throm...

journal_title：Atherosclerosis

authors： Sadat U,Weerakkody RA,Bowden DJ,Young VE,Graves MJ,Li ZY,Tang TY,Gaunt ME,Hayes PD,Gillard JH

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:Recent studies have suggested that circulating malondialdehyde-modified low-density lipoprotein (MDA-LDL) is a useful marker for the identification of patients with coronary artery disease (CAD). However, the role of MDA-LDL in atherogenic mechanisms has not yet been fully determined. METHOD AND RESULTS:We i...

journal_title：Atherosclerosis

authors： Miyazaki T,Shimada K,Sato O,Kotani K,Kume A,Sumiyoshi K,Sato Y,Ohmura H,Watanabe Y,Mokuno H,Daida H

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:Previous studies have found polymorphisms of the HDL receptor, SR-BI, to be associated with plasma HDL-C in women, but not men, suggesting a modifying role of estrogen. We examined whether the association between SR-BI genotypes and HDL-C is modified by use of unopposed estrogen in community-dwelling postmen...

journal_title：Atherosclerosis

authors： Richard E,von Muhlen D,Barrett-Connor E,Alcaraz J,Davis R,McCarthy JJ

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Atherosclerotic plaques are heterogeneous with respect to inflammation, calcification, vascularity, oxygen, and temperature. We hypothesized that they also vary in pH and measured pH in living human carotid endarterectomized atherosclerotic plaques (CEA), Watanabe heritable hyperlipidemic (WHHL) rabbit aorta...

journal_title：Atherosclerosis

authors： Naghavi M,John R,Naguib S,Siadaty MS,Grasu R,Kurian KC,van Winkle WB,Soller B,Litovsky S,Madjid M,Willerson JT,Casscells W

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVE:We aimed to determine, whether the amount of local pericoronary fat volume is associated with the presence of plaque burden in the underlying coronary artery segment. METHODS:We assessed 311 coronary segments from ECG-gated contrast-enhanced dual-source computed tomography for presence of plaque as well as s...

journal_title：Atherosclerosis

authors： Mahabadi AA,Reinsch N,Lehmann N,Altenbernd J,Kälsch H,Seibel RM,Erbel R,Möhlenkamp S

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVE:The association of egg consumption with subclinical coronary atherosclerosis remains unknown. Our aim was to examine the association between egg consumption and prevalence of coronary artery calcium (CAC). METHODS:Cross-sectional study of 23,417 asymptomatic adult men and women without a history of cardiovas...

journal_title：Atherosclerosis

authors： Choi Y,Chang Y,Lee JE,Chun S,Cho J,Sung E,Suh BS,Rampal S,Zhao D,Zhang Y,Pastor-Barriuso R,Lima JA,Shin H,Ryu S,Guallar E

更新日期：2015-08-01 00:00:00

abstract：:The possible role of four candidate genes in lipid and lipoprotein response to diet was examined in 214 members of two large kibbutz settlements in Israel. Four site polymorphisms (signal peptide insertion/deletion, XbaI, EcoRI and MspI) of the apo B gene, the common apo E genotypes, three common mutations (T-93G, S44...

journal_title：Atherosclerosis

authors： Friedlander Y,Leitersdorf E,Vecsler R,Funke H,Kark J

更新日期：2000-09-01 00:00:00

abstract：:A combined gross and histologic study carried out on 270 selected male subjects with the common type of distribution of the coronary arteries revealed a natural resistance to intimal thickening and plaque development exhibited by the left main coronary artery and by the first centimeter of the right coronary artery. T...

journal_title：Atherosclerosis

authors： Velican C,Velican D

更新日期：1984-02-01 00:00:00

abstract：:The possible mechanisms of action of probucol on the metabolism of low density lipoprotein and of high density lipoprotein were studied in 5 hyperlipidaemic subjects. The kinetics of LDL-B protein and of HDL-AI protein were determined by 2-pool analysis of specific radioactivity-time curves after reinjection of 131I-l...

journal_title：Atherosclerosis

authors： Nestel PJ,Billington T

更新日期：1981-01-01 00:00:00

abstract：:The hypolipidaemic effect of guar gum (30 g/day) was examined in a double blind placebo-controlled crossover study in 9 patients with primary hyperlipidaemia. The treatment periods were of six weeks duration. Cholesterol levels in low density lipoprotein (LDL) were decreased by 11.5% and in intermediate density lipopr...

journal_title：Atherosclerosis

authors： Turner PR,Tuomilehto J,Happonen P,La Ville AE,Shaikh M,Lewis B

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:Epicardial adipose tissue (EAT) mass correlates with metabolic syndrome and coronary artery disease (CAD). However, little is known about the expression of genes involved in triglyceride (TG) storage and mobilization in EAT. We therefore analyzed the expression of genes involved in fat mobilization in EAT in...

journal_title：Atherosclerosis

authors： Jaffer I,Riederer M,Shah P,Peters P,Quehenberger F,Wood A,Scharnagl H,März W,Kostner KM,Kostner GM

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To investigate cross-sectional and longitudinal associations between serum total bilirubin (TB) and dyslipidemia. METHODS:Odds ratios (ORs) of prevalent dyslipidemia for TB were calculated in 2113 men and 1265 women. Correlation coefficients between baseline TB as well as the change in TB over 5 years and ba...

journal_title：Atherosclerosis

authors： Oda E

更新日期：2015-03-01 00:00:00

abstract：:This study examined the effects of various polyunsaturated fatty acid (PUFA, P)/saturated fatty acid (SFA, S) ratio versus PUFA + monounsaturated fatty acid (MUFA, M)/SFA ratio on lipid metabolism. The P/S ratio of dietary fat was fixed at a certain level (0.5, 1, 2, or 4, respectively) for each of four pairs of rat g...

journal_title：Atherosclerosis

authors： Chang NW,Huang PC

更新日期：1999-01-01 00:00:00

abstract：INTRODUCTION:Toll-like receptors play an important role in the innate immune system and are found to be crucial in severe diseases like sepsis, atherosclerosis, and arthritis. TLR2 and TLR4 expression is upregulated in the inflammatory diseases. Angiotensin II in addition to stimulating vasoconstriction also induces an...

journal_title：Atherosclerosis

authors： Dasu MR,Riosvelasco AC,Jialal I

更新日期：2009-01-01 00:00:00

abstract：:We investigated the possibility that established atherosclerosis and xanthomas in mature WHHL rabbits could be suppressed or even regressed when their serum cholesterol levels were kept extremely low. Ten-month-old WHHL rabbits were divided into 3 groups, i.e. control rabbits, sacrificed at age 10 months, and placebo ...

journal_title：Atherosclerosis

authors： Shiomi M,Ito T,Watanabe Y,Tsujita Y,Kuroda M,Arai M,Fukami M,Fukushige J,Tamura A

更新日期：1990-07-01 00:00:00

abstract：BACKGROUND:Toll like receptors (TLR) have been recognized for their role in atherosclerotic lesion development and progression. Endogenous TLR ligands that are also expressed in atherosclerotic tissues have been shown to promote atherosclerosis in mice. Since repetitive stimulation of TLR induces an attenuated inflamma...

journal_title：Atherosclerosis

authors： Schoneveld AH,Hoefer I,Sluijter JP,Laman JD,de Kleijn DP,Pasterkamp G

更新日期：2008-03-01 00:00:00

abstract：:We examined cross-sectional associations between sex hormones and carotid artery intimal-medial thickness (cIMT) and coronary artery calcium in women in the Multi-Ethnic Study of Atherosclerosis. Serum testosterone, estradiol, sex hormone binding globulin (SHBG), and dehydroepiandrosterone levels were measured in 1947...

journal_title：Atherosclerosis

authors： Ouyang P,Vaidya D,Dobs A,Golden SH,Szklo M,Heckbert SR,Kopp P,Gapstur SM

更新日期：2009-05-01 00:00:00

abstract：:Incubated human peripheral blood monocytes release a factor(s) which specifically stimulates homologous vascular smooth muscle (SMC) but not endothelial cells (EC) to proliferate in vitro. Conditioned medium from activated monocytes significantly (P less than 0.001) stimulated proliferation of SMC within 6 days of cul...

journal_title：Atherosclerosis

authors： Ziats NP,Robertson AL Jr

更新日期：1981-02-01 00:00:00

abstract：:The Framingham risk score (FRS), developed in a white cohort aged 30-74 years, is increasingly used in the early risk identification for coronary artery disease (CAD). This study examines the relationship between FRS and carotid artery intima-media thickness (IMT), a surrogate marker of coronary atherosclerosis, in bl...

journal_title：Atherosclerosis

authors： Kieltyka L,Urbina EM,Tang R,Bond MG,Srinivasan SR,Berenson GS

更新日期：2003-09-01 00:00:00

abstract：:Mast cells (MCs) contribute to atherogenesis by releasing pro-inflammatory mediators to activate vascular cells and other inflammatory cells. This study examined whether MC activation or stabilization affects diet-induced atherosclerosis in low-density lipoprotein receptor-deficient (Ldlr(-/-)) mice. When Ldlr(-/-) mi...

journal_title：Atherosclerosis

authors： Wang J,Sjöberg S,Tia V,Secco B,Chen H,Yang M,Sukhova GK,Shi GP

更新日期：2013-08-01 00:00:00

abstract：:Self-administration of anabolic-androgenic steroids to increase muscular strength and lean body mass has been used widely among athletes. Flow mediated dilatation (FMD) determined by ultrasound of the brachial artery is accepted as both an in vivo index of endothelial function and an indicator for future atheroscleros...

journal_title：Atherosclerosis

authors： Ebenbichler CF,Sturm W,Gänzer H,Bodner J,Mangweth B,Ritsch A,Sandhofer A,Lechleitner M,Föger B,Patsch JR

更新日期：2001-10-01 00:00:00

abstract：:In the rabbit, dietary cholesterol downregulates the hepatic LDL receptor and concomitant treatment with 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors partly restores its expression. The aim of this study was to determine whether the LDL receptor activity of circulating mononuclear cells would r...

journal_title：Atherosclerosis

authors： Roach PD,Kerry NL,Whiting MJ,Nestel PJ

更新日期：1993-07-01 00:00:00

abstract：:Measurements of aortic length and circumference in 336 post-mortem specimens confirm earlier, neglected observations on the progressive increase in aortic size which occurs with advancing years. The increase is not related to atherosclerosis , or to hypertension and seems to be part of a true ageing process. The value...

journal_title：Atherosclerosis

authors： Mitchell JR,Adams JH

更新日期：1977-08-01 00:00:00

abstract：:The metabolic syndrome (MetS) is represented by the co-occurrence of multiple metabolic and physiologic risk factors for both type 2 diabetes mellitus and atherosclerotic cardiovascular diseases. In spite of its high frequency and association with morbidity and mortality in the adult population, very little is known a...

journal_title：Atherosclerosis

authors： Maggi S,Noale M,Zambon A,Limongi F,Romanato G,Crepaldi G,ILSA Working Group.

更新日期：2008-04-01 00:00:00

abstract：:The proband is a 50 year-old woman born from a consanguineous marriage. She has been suffering from angina pectoris since the age of 38 and underwent coronary bypass surgery for three-vessel disease at 48. The presence of low plasma levels of total cholesterol and high density lipoprotein (HDL) cholesterol (2.4 and 0....

journal_title：Atherosclerosis

authors： Bertolini S,Pisciotta L,Seri M,Cusano R,Cantafora A,Calabresi L,Franceschini G,Ravazzolo R,Calandra S

更新日期：2001-02-15 00:00:00

abstract：BACKGROUND AND AIMS:The TNF-superfamily member sTWEAK and its scavenger receptor sCD163 are potentially involved in pathophysiological processes of atherosclerosis. In patients with peripheral arterial disease, previous research has shown that sTWEAK and the sCD163/sTWEAK ratio were independently associated with long t...

journal_title：Atherosclerosis

authors： Mrak D,Zierfuss B,Höbaus C,Herz CT,Pesau G,Schernthaner GH

更新日期：2021-01-01 00:00:00