7-Ketocholesteryl-9-carboxynonanoate enhances the expression of ATP-binding cassette transporter A1 via CD36.

abstract：:Several studies indicate that the inter-individual variation in plasma concentrations of lipoprotein(a) (Lp(a)) is mainly under genetic control. To define the effect of three DNA polymorphisms on apolipoprotein(a) (apo(a)) expression, we have determined plasma Lp(a) concentrations, apo(a) isoform size, KpnI allele siz...

journal_title：Atherosclerosis

authors： Valenti K,Aveynier E,Leauté S,Laporte F,Hadjian AJ

更新日期：1999-11-01 00:00:00

abstract：OBJECTIVE:Atherosclerosis is a multi-step process, where lipids, inflammatory and hemostatic mediators orchestrate plaque formation and progression, which subsequently may lead to myocardial infarction and ischemic stroke. Familial hypercholesterolemia (FH) is associated with increased risk of premature atherosclerosis...

journal_title：Atherosclerosis

authors： Narverud I,Retterstøl K,Iversen PO,Halvorsen B,Ueland T,Ulven SM,Ose L,Aukrust P,Veierød MB,Holven KB

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVES:To examine the longitudinal association between toenail selenium levels and subclinical atherosclerosis over an 18-year period. METHODS:Toenail selenium concentrations were examined among 3112 Americans age 20-32 years in 1987 and measured by instrumental neutron-activation analysis. Subclinical atheroscler...

journal_title：Atherosclerosis

authors： Xun P,Liu K,Morris JS,Daviglus ML,He K

更新日期：2010-06-01 00:00:00

abstract：:Platelet phospholipid composition was analyzed before and after extracorporeal removal of low density lipoproteins (LDL) by LDL apheresis in six patients with familial hypercholesterolemia. Elevated levels of total plasma cholesterol and the portion of plasma cholesterol carried by LDL were reduced by 56 and 66% after...

journal_title：Atherosclerosis

authors： Bräutigam R,Bräutigam C,Lorenz R,Richter WO,Engelmann B

更新日期：1997-05-01 00:00:00

abstract：:We examined the interactive effect of oxidized low density lipoprotein (LDL) and ascorbic acid on collagen production in cultured smooth muscle cells (SMCs). Porcine aortic SMCs were incubated with 50-200 micrograms/ml of human LDL with/without 5 microM Cu2+ for 24 h. Collagen production was assayed by successive salt...

journal_title：Atherosclerosis

authors： Jimi S,Saku K,Uesugi N,Sakata N,Takebayashi S

更新日期：1995-07-01 00:00:00

abstract：:Cardiovascular disease (CVD) is currently the second most frequent cause of death (after cancer) among HIV-positive subjects. The clinical use of highly active antiretroviral therapy (HAART) has dramatically reduced mortality and morbidity in HIV-positive population, leading to prolonged and improved quality of life. ...

journal_title：Atherosclerosis

authors： Giannarelli C,Klein RS,Badimon JJ

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:High homocysteine level is a risk factor for atherosclerosis and has been associated with lacunar infarcts (LIs), white matter lesions (WML) and cognitive dysfunction. It is unclear whether homocysteine is associated with cerebral small vessel disease (cSVD) on top of pre-existent atherosclerosis. We evaluate...

journal_title：Atherosclerosis

authors： Kloppenborg RP,Nederkoorn PJ,van der Graaf Y,Geerlings MI

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Classically, peripheral arterial disease (PAD) is diagnosed by a low ankle-brachial index (ABI), but the diagnosis can also be made based on toe-brachial index (TBI) measurements. The objective of this study was to characterize patients with low TBI but normal ABI, and chart potential underestimatio...

journal_title：Atherosclerosis

authors： Høyer C,Høgh AL,Sandermann J,Zacho HD,Petersen LJ

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:Pravastatin has been reported to elevate circulating adiponectin levels in patients with various insulin resistant state, hypertension, coronary artery disease, and hypercholesterolemia. This study aimed to evaluate whether pravastatin increase serum total and high molecular weight adiponectin levels and impr...

journal_title：Atherosclerosis

authors： Kim JH,Lee MR,Shin JA,Lee SS,Lee JM,You SJ,Yoon KH,Chang SA

更新日期：2013-04-01 00:00:00

abstract：:Blood serum of most patients with coronary heart disease (CHD) caused a 2-5-fold increase in the total cholesterol content of smooth muscle cells cultured from unaffected human aortic intima, i.e. possessed an atherogenic potential manifested in culture. Removal of immunoglobulins G and M from an atherogenic serum bro...

journal_title：Atherosclerosis

authors： Tertov VV,Orekhov AN,Sayadyan KS,Serebrennikov SG,Kacharava AG,Lyakishev AA,Smirnov VN

更新日期：1990-04-01 00:00:00

abstract：AIMS:Leukocyte telomere length (LTL) is shortened in patients with clinical atherosclerosis (AS). Here we aimed to explore the contribution of elevated homocysteine (Hcy) level to LTL shortening in AS patients and the underlying mechanism. METHODS:Circulating leukocytes were collected from 197 patients with AS and 165...

journal_title：Atherosclerosis

authors： Zhang D,Wen X,Wu W,Xu E,Zhang Y,Cui W

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:The benefits of fish oil fatty acids eicosapentaenoic (EPA) and docosahexaenoic acids (DHA) on plasma lipid profiles have been inconsistent but may partially depend on individual Apolipoprotein E (APOE) genotypes. We aimed to determine whether APOE genotype modifies the association of lipid profile characteri...

journal_title：Atherosclerosis

authors： Liang S,Steffen LM,Steffen BT,Guan W,Weir NL,Rich SS,Manichaikul A,Vargas JD,Tsai MY

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:Evidence has demonstrated profound influence of genetic background on cardiovascular phenotypes. Murine models in Marfan syndrome (MFS) have shown that genetic background-related variations affect thoracic aortic aneurysm formation, rupture, and lifespan of mice. MFS mice with C57Bl/6 genetic background are l...

journal_title：Atherosclerosis

authors： Dale MA,Suh MK,Zhao S,Meisinger T,Gu L,Swier VJ,Agrawal DK,Greiner TC,Carson JS,Baxter BT,Xiong W

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Observations in the past have hypothesized an association between body iron status and coronary heart disease (CHD). Epidemiological studies to date have however been inconclusive without the existence of strongly positive or strongly negative associations between iron status and coronary heart disease. OBJ...

journal_title：Atherosclerosis

authors： Das De S,Krishna S,Jethwa A

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:A direct correlation between blood glucose levels and the microvascular complications of diabetes is well established. However, the effects of hyperglycaemia on the vasa vasorum, a microvascular network which surrounds and supplies the walls of large arteries, is not known. The objective of this study is to i...

journal_title：Atherosclerosis

authors： Veerman KJ,Venegas-Pino DE,Shi Y,Khan MI,Gerstein HC,Werstuck GH

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Increased activity of matrix metalloproteinase (MMP)-2 is observed in aortas of different models of hypertension, and its activation is directly mediated by oxidative stress. As quercetin is an important flavonoid with significant antioxidant effects, the hypothesis here is that quercetin will reduc...

journal_title：Atherosclerosis

authors： Pereira SC,Parente JM,Belo VA,Mendes AS,Gonzaga NA,do Vale GT,Ceron CS,Tanus-Santos JE,Tirapelli CR,Castro MM

更新日期：2018-03-01 00:00:00

abstract：:Degranulated mast cells are present in the human arterial intima. After degranulation of rat serosal mast cells, the secreted neutral serine protease chymase remains bound to the heparin proteoglycan matrix of the exocytosed granules, forming granule remnants. Addition of granule remnants to human aortic intimal fluid...

journal_title：Atherosclerosis

authors： Lindstedt L,Lee M,Kovanen PT

更新日期：2001-03-01 00:00:00

abstract：:Serum lipids, lipoproteins and Achilles tendon thickness in 52 patients with heterozygous familial hypercholesterolemia (FH) were investigated in order to clarify what are the important factors for the development of coronary artery disease (CAD) in heterozygous FH patients. There were no significant differences in th...

journal_title：Atherosclerosis

authors： Hirobe K,Matsuzawa Y,Ishikawa K,Tarui S,Yamamoto A,Nambu S,Fujimoto K

更新日期：1982-08-01 00:00:00

abstract：BACKGROUND:Increasing age and cholesterol levels, male gender, and family history of early coronary heart disease (CHD) are associated with early onset of CHD in familial hypercholesterolemia (FH). OBJECTIVE:Assess subclinical atherosclerosis by computed tomography coronary angiography (CTCA) and its association with ...

journal_title：Atherosclerosis

authors： Miname MH,Ribeiro MS 2nd,Parga Filho J,Avila LF,Bortolotto LA,Martinez LR,Rochitte CE,Santos RD

更新日期：2010-12-01 00:00:00

abstract：:A chondroitin sulfate-dermatan sulfate proteoglycan was isolated from bovine aorta intima by extraction of the tissue with 4 M guanidine hydrochloride. The proteoglycan was purified by CsCl isopycnic centrifugation followed by gel filtration and ion exchange chromatography. A monoclonal antibody C8F4 was developed to ...

journal_title：Atherosclerosis

authors： Radhakrishnamurthy B,Jeansonne N,Tracy RE,Berenson GS

更新日期：1993-01-25 00:00:00

abstract：:Leukotriene B(4) (LTB(4)) is a pro-inflammatory lipid mediator generated by the enzymes 5-lipoxygenase (5-LO) and LTA(4)-hydrolase. LTB(4) signals primarily through its G protein-coupled receptor BLT1, which is highly expressed on specific leukocyte subsets. Recent genetic studies in humans as well as knockout studies...

journal_title：Atherosclerosis

authors： Kristo F,Hardy GJ,Anderson TJ,Sinha S,Ahluwalia N,Lin AY,Passeri J,Scherrer-Crosbie M,Gerszten RE

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND AND AIMS:Results from prospective studies evaluating the relationship between elevated lipoprotein-associated phospholipase A2 (Lp-PLA2) activity and incident peripheral arterial disease (PAD) have been mixed. We investigated whether higher Lp-PLA2 levels are associated with increased risk of incident PAD an...

journal_title：Atherosclerosis

authors： Garg PK,Norby FL,Polfus LM,Boerwinkle E,Gibbs RA,Grove ML,Folsom AR,Garimella PS,Matsushita K,Hoogeveen RC,Ballantyne CM

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:Adiponectin is one of several important, metabolically active cytokines secreted from adipose tissue. Epidemiologic studies have associated low circulating levels of this adipokine with multiple metabolic disorders including obesity, insulin resistance, type II diabetes, and cardiovascular disease. To investi...

journal_title：Atherosclerosis

authors： Luo N,Chung BH,Wang X,Klein RL,Tang CK,Garvey WT,Fu Y

更新日期：2013-05-01 00:00:00

abstract：:Even when administered at a comparatively low level, dietary cholesterol produces significant changes in the properties of plasma lipoproteins in rats, particularly the d less than or equal to 1.006 g/ml fraction (VLDL). The occurrence of these changes is promoted by dietary casein. To test the hypothesis that these d...

journal_title：Atherosclerosis

authors： Eklund A,Sjöblom L,Ostlund-Lindqvist AM

更新日期：1986-11-01 00:00:00

abstract：:Research has indicated that inflammation promote all phases of atherosclerosis. The current study tested the hypothesis that rhinosinusitis is a risk marker for myocardial infarction (MI). Data on the general population were obtained from the Taiwan Longitudinal Health Insurance Database 2005 (LHID2005). The study coh...

journal_title：Atherosclerosis

authors： Hao WR,Lin HW,Chao PZ,Wu CW,Yen TH,Liu JC,Liou TH

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Acrolein is a dietary aldehyde that is present in high concentrations in alcoholic beverages and foods including cheese, donuts and coffee. It is also abundant in tobacco smoke, automobile exhaust and industrial waste and is generated in vivo during inflammation and oxidative stress. OBJECTIVES:The goal of ...

journal_title：Atherosclerosis

authors： Srivastava S,Sithu SD,Vladykovskaya E,Haberzettl P,Hoetker DJ,Siddiqui MA,Conklin DJ,D'Souza SE,Bhatnagar A

更新日期：2011-04-01 00:00:00

abstract：:Vascular endothelial cell death contributes to the progression of atherosclerotic lesion, and several transcriptional regulators are involved in the process. Activating transcription factor 3/liver regenerating factor-1 (ATF3/LRF-1), a stress-inducible transcriptional repressor, was shown to be highly expressed in vas...

journal_title：Atherosclerosis

authors： Nawa T,Nawa MT,Adachi MT,Uchimura I,Shimokawa R,Fujisawa K,Tanaka A,Numano F,Kitajima S

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND & AIMS:Dysbiosis of the gut microbiota is associated with increased levels of circulating lipopolysaccharide (LPS) and subsequent activation of systemic inflammation. Diet is an important modulator of the gut microbiome. We aimed to investigate whether circulating markers of gut-related inflammation, LPS bin...

journal_title：Atherosclerosis

authors： Awoyemi A,Trøseid M,Arnesen H,Solheim S,Seljeflot I

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:In coronary artery disease (CAD), concomitant peripheral arterial disease (PAD) entails more severe coronary atherosclerosis. We investigated whether the inflammatory status of affected limbs impairs coronary artery endothelial function (CAEF). METHODS:We measured the neutrophil myeloperoxidase content (NMP...

journal_title：Atherosclerosis

authors： Brevetti G,Piscione F,Cirillo P,Galasso G,Schiano V,Barbato E,Scopacasa F,Chiariello M

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Familial hypercholesterolaemia (FH) is a powerful risk factor for cardiovascular (CV) events. High levels of low-density lipoprotein cholesterol (LDL-C) since birth are linked to the early onset of atherosclerotic disease. A genetic mutation determining FH is present in about one subject out of 250;...

journal_title：Atherosclerosis

authors： Gulizia MM,Maggioni AP,Abrignani MG,Bilato C,Mangiacapra F,Sanchez FA,Piovaccari G,Montagna L,Marini M,De Biasio M,Averna M,Casula M,Colivicchi F,Fabbri G,Lucci D,Zampoleri V,Catapano AL,POSTER Investigators.

更新日期：2020-09-01 00:00:00