HbA1c is significantly associated with arterial stiffness but not with carotid atherosclerosis in a community-based population without type 2 diabetes: The Dong-gu study.

abstract：:Cilostazol is an antiplatelet drug, which has beneficial effects in treatment of intermittent claudication and decreases serum triacyiglycerol level in these patients. In this study, we examined adipogenic potency of cilostazol using 3T3-L1 preadipocyte cell line because cilostazol is one of the tissue specific phosph...

journal_title：Atherosclerosis

authors： Hirose T,Kurebayashi S,Kasayama S

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Leukocyte count is recognized as an inflammatory marker and a predictor of cardiovascular events. However, it is uncertain whether the contribution of leukocyte count to the risk of cardiovascular disease is independent of smoking. METHODS:The subjects were 4492 male employees aged 40-59 years who worked fo...

journal_title：Atherosclerosis

authors： Imano H,Sato S,Kitamura A,Kiyama M,Ohira T,Shimamoto T,Iso H

更新日期：2007-11-01 00:00:00

abstract：:This is a study to define the profile of chemokine receptors expressed on isolated infiltrating lymphocytes in human abdominal aortic aneurysms (AAAs), and to examine their role in lymphoid recruitment. AAA T-lymphocytes were CXCR4-positive, CCR7-negative and partially CXCR3 and CCR5-positive. Functionally, AAA T-cell...

journal_title：Atherosclerosis

authors： Ocaña E,Pérez-Requena J,Bohórquez JC,Brieva JA,Rodríguez C

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:Periostin is dramatically upregulated in rat carotid arteries after balloon injury. The objective of the present study was to understand mechanisms underlying periostin upregulation in balloon-injured rat carotid arteries and in cultured vascular smooth muscle cells (VSMCs). METHODS AND RESULTS:Periostin pro...

journal_title：Atherosclerosis

authors： Li G,Oparil S,Sanders JM,Zhang L,Dai M,Chen LB,Conway SJ,McNamara CA,Sarembock IJ

更新日期：2006-10-01 00:00:00

abstract：:This study assessed the efficacy of rosuvastatin for reducing plasma low-density lipoprotein (LDL) cholesterol after 18 weeks of open-label, forced titration in patients with homozygous familial hypercholesterolaemia (hoFH) and compared the efficacy of rosuvastatin 80 mg and atorvastatin 80 mg. Forty-four patients age...

journal_title：Atherosclerosis

authors： Marais AD,Raal FJ,Stein EA,Rader DJ,Blasetto J,Palmer M,Wilpshaar W

更新日期：2008-03-01 00:00:00

abstract：:In the rabbit, dietary cholesterol downregulates the hepatic LDL receptor and concomitant treatment with 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors partly restores its expression. The aim of this study was to determine whether the LDL receptor activity of circulating mononuclear cells would r...

journal_title：Atherosclerosis

authors： Roach PD,Kerry NL,Whiting MJ,Nestel PJ

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:CD163 is a new potential scavenger receptor of Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) which elicits diverse biologic actions involved in atherosclerosis. We have analyzed the importance of TWEAK-CD163 interaction in atherosclerosis. METHODS:TWEAK and CD163 interaction was studied in cu...

journal_title：Atherosclerosis

authors： Moreno JA,Muñoz-García B,Martín-Ventura JL,Madrigal-Matute J,Orbe J,Páramo JA,Ortega L,Egido J,Blanco-Colio LM

更新日期：2009-11-01 00:00:00

abstract：:Circulating soluble intercellular adhesion molecule-1 (sICAM-1) is a biochemical marker of inflammation. We performed variance-components-based quantitative genetic analyses in SOLAR of sICAM-1 in 1170 individuals from Mexican American families in the San Antonio Family Heart Study. The trait is heritable (h(2)=0.50+/...

journal_title：Atherosclerosis

authors： Kent JW Jr,Mahaney MC,Comuzzie AG,Göring HH,Almasy L,Dyer TD,Cole SA,MacCluer JW,Blangero J

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:CVD risk increases in women after menopause. Recent data suggest higher levels of complement protein C3 and cardiovascular fat (CF) in postmenopausal women. Whether complement proteins are associated with early markers of atherosclerosis in healthy midlife women has never been evaluated. Additionally, the po...

journal_title：Atherosclerosis

authors： Nagaraj N,Matthews KA,Shields KJ,Barinas-Mitchell E,Budoff MJ,El Khoudary SR

更新日期：2015-12-01 00:00:00

abstract：:High-density lipoprotein (HDL) cholesteryl esters (CE) are taken up by many cells without parallel uptake of HDL apolipoproteins. This selective uptake of HDL CE was investigated in human monocyte-derived macrophages (HMM). HDL3 (d = 1.125-1.21 g/ml) was labeled in its apolipoprotein A-I moiety with 125I and in its CE...

journal_title：Atherosclerosis

authors： Rinninger F,Deichen JT,Jäckle S,Windler E,Greten H

更新日期：1994-02-01 00:00:00

abstract：OBJECTIVE:P-selectin is a cellular adhesion molecule that has been shown to be crucial in development of coronary heart disease (CHD). We sought to determine the role of P-selectin on the risk of atherosclerosis in a large multi-ethnic population. METHODS:Data from the Multi-Ethnic Study of Atherosclerosis (MESA), inc...

journal_title：Atherosclerosis

authors： Bielinski SJ,Berardi C,Decker PA,Kirsch PS,Larson NB,Pankow JS,Sale M,de Andrade M,Sicotte H,Tang W,Hanson NQ,Wassel CL,Polak JF,Tsai MY

更新日期：2015-05-01 00:00:00

abstract：PURPOSE:To investigate whether atherosclerosis can be prevented by magnetically labeled endothelial progenitor cells (EPCs) in rabbits. MATERIALS AND METHODS:EPCs derived from rabbit periphery blood were labeled with a superparamagnetic iron oxide (SPIO) agent Fe(2)O(3)-poly-L-lysine (Fe(2)O(3)-PLL). Rabbit atheroscle...

journal_title：Atherosclerosis

authors： Ma ZL,Mai XL,Sun JH,Ju SH,Yang X,Ni Y,Teng GJ

更新日期：2009-07-01 00:00:00

abstract：:Serum lipids, lipoproteins and Achilles tendon thickness in 52 patients with heterozygous familial hypercholesterolemia (FH) were investigated in order to clarify what are the important factors for the development of coronary artery disease (CAD) in heterozygous FH patients. There were no significant differences in th...

journal_title：Atherosclerosis

authors： Hirobe K,Matsuzawa Y,Ishikawa K,Tarui S,Yamamoto A,Nambu S,Fujimoto K

更新日期：1982-08-01 00:00:00

abstract：:Dietary plant proteins may lower plasma cholesterol and LDL concentrations in hypercholesterolemic patients when substituted for animal proteins, particularly in diets with low cholesterol and saturated fat content. Plant protein diets appear, however, to be without effect on plasma lipoprotein levels in normal subjec...

journal_title：Atherosclerosis

authors： Meinertz H,Faergeman O,Nilausen K,Chapman MJ,Goldstein S,Laplaud PM

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND AND AIMS:Left ventricular hypertrophy (LVH), assessed by electrocardiogram (ECG), is associated with increased risk for stroke. However, few studies that evaluated whether ECG-detected LVH predicts ischemic stroke severity and outcome. We aimed to evaluate these associations. METHODS:We prospectively studie...

journal_title：Atherosclerosis

authors： Tziomalos K,Sofogianni A,Angelopoulou SM,Christou K,Kostaki S,Papagianni M,Satsoglou S,Spanou M,Savopoulos C,Hatzitolios AI

更新日期：2018-07-01 00:00:00

abstract：OBJECTIVE:Microvascular mechanisms are increasingly recognized as being involved in a significant proportion of coronary artery disease (CAD) cases, but their exact contribution or role is unclear. We aimed to define the association between retinal microvascular signs and both CAD extent and severity. METHODS:1120 par...

journal_title：Atherosclerosis

authors： Gopinath B,Chiha J,Plant AJ,Thiagalingam A,Burlutsky G,Kovoor P,Liew G,Mitchell P

更新日期：2014-09-01 00:00:00

abstract：:Sitostanol (24-ethyl-5 alpha-cholestan-3 beta-ol), a hydrogenated derivative of sitosterol, was administered in a low dose (1.5 g/day) for 4 weeks to 6 patients with hypercholesterolemia. Total cholesterol was reduced significantly after 3 and 4 weeks by 10 and 15%, respectively. The reduction of total cholesterol was...

journal_title：Atherosclerosis

authors： Heinemann T,Leiss O,von Bergmann K

更新日期：1986-09-01 00:00:00

abstract：:beta-Oxidation of long-chain fatty acids increases many-fold in atherosclerotic aortas; this may be due to an increase in the activity of the mitochondrial enzyme hexadecanoyl-CoA: carnitine O-hexadecanoyltransferase EC 2.3.1.23 (trivial name: carnitine palmitoyltransferase, CPT). To investigate this possibility, an a...

journal_title：Atherosclerosis

authors： Gillies PJ,Bell FP

更新日期：1979-09-01 00:00:00

abstract：OBJECTIVE:Peroxisome proliferator-activated receptors alpha (PPARalpha) is a target gene for atherosclerosis and cardiovascular diseases. However, effects of PPARalpha on endothelial nitric oxide synthase (eNOS) remain unknown. We investigated the eNOS regulation by bezafibrate, a ligand of PPARalpha, and involved sign...

journal_title：Atherosclerosis

authors： Wang Y,Wang Y,Yang Q,Yan JT,Zhao C,Cianflone K,Wang DW

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND AND AIMS:The mechanisms that drive atherosclerotic plaque progression and destabilization in humans remain largely unknown. Laboratory models are needed to study these mechanisms under controlled conditions. The aim of this study was to establish a new ex vivo model of human atherosclerotic plaques that pres...

journal_title：Atherosclerosis

authors： Lebedeva A,Vorobyeva D,Vagida M,Ivanova O,Felker E,Fitzgerald W,Danilova N,Gontarenko V,Shpektor A,Vasilieva E,Margolis L

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:P2X(7) receptor (P2X(7)R), upon its stimulation with extracellular ATP, modulates several inflammatory responses in different cell types. No information is available on its presence in human adipocytes and its potential involvement in the chronic inflammation associated with metabolic syndrome (MS). Therefore...

journal_title：Atherosclerosis

authors： Madec S,Rossi C,Chiarugi M,Santini E,Salvati A,Ferrannini E,Solini A

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND AND PURPOSES:Pulse wave analysis (PWV), a marker of aortic stiffness, has independent predictive value for cardiovascular morbidity and mortality in both healthy and high-risk populations, especially fatal stroke, and for long-term functional stroke prognosis. Whether arterial stiffness and wave reflection a...

journal_title：Atherosclerosis

authors： Gąsecki D,Rojek A,Kwarciany M,Kowalczyk K,Boutouyrie P,Nyka W,Laurent S,Narkiewicz K

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Toll like receptors (TLR) have been recognized for their role in atherosclerotic lesion development and progression. Endogenous TLR ligands that are also expressed in atherosclerotic tissues have been shown to promote atherosclerosis in mice. Since repetitive stimulation of TLR induces an attenuated inflamma...

journal_title：Atherosclerosis

authors： Schoneveld AH,Hoefer I,Sluijter JP,Laman JD,de Kleijn DP,Pasterkamp G

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Previous studies have shown that computed tomography coronary angiography (CTA) in patients with suspected coronary artery disease (CAD) predicts short term adverse events. However, there is no current data on whether identifying atherosclerosis on CTA impacts outcomes. We performed a case-control study to a...

journal_title：Atherosclerosis

authors： Budoff MJ,Liu S,Chow D,Flores F,Hsieh B,Gebow D,DeFrance T,Ahmadi N

更新日期：2014-12-01 00:00:00

abstract：UNLABELLED:In the last few years it has been proved that risk factors for atherosclerosis are present in children and adolescents, and that already at this early age they are connected with anatomic, atheromatous changes in vessels. These changes can not be fully explained as occurring in young people exhibiting tradit...

journal_title：Atherosclerosis

authors： Glowinska B,Urban M,Koput A,Galar M

更新日期：2003-04-01 00:00:00

abstract：:High level of plasma very low-density lipoprotein (VLDL) has been identified as a risk factor for coronary heart disease. Recent evidence suggests that excess VLDL induces inflammatory responses in macrophages and vascular endothelial cells. The Japan EPA Lipid Intervention Study (JELIS), a large scale clinical trial,...

journal_title：Atherosclerosis

authors： Jinno Y,Nakakuki M,Kawano H,Notsu T,Mizuguchi K,Imada K

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Sleep-disordered breathing (SDB) is associated with clinical cardiovascular disease (CVD), but its relation to subclinical atherosclerosis remains to be determined. METHODS:We analyzed the cross-sectional associations of SDB, measured by the respiratory disturbance index (RDI), a hypoxemia index, and an aro...

journal_title：Atherosclerosis

authors： Wattanakit K,Boland L,Punjabi NM,Shahar E

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Diabetes is a major risk factor for the development of atherosclerosis. Hyperglycemia stimulates vascular smooth muscle cells (VSMC) to secrete ligands that bind to the αVβ3 integrin, a receptor that regulates VSMC proliferation and migration. This study determined whether an antibody that had previ...

journal_title：Atherosclerosis

authors： Maile LA,Busby WH,Xi G,Gollahan KP,Flowers W,Gafbacik N,Gafbacik S,Stewart K,Merricks EP,Nichols TC,Bellinger DA,Clemmons DR

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:To examine whether genetic polymorphisms in the 5-lipoxygenase activating protein (ALOX5AP) confer an increased risk to angiographically proven coronary artery disease (CAD) in a case-control study of a Midwestern population in the US. METHODS:We genotyped 7 SNPs (SG13S25, SG13S89, SG13S41, SG13S377, SG13S35...

journal_title：Atherosclerosis

authors： Tsai AK,Li N,Hanson NQ,Tsai MY,Tang W

更新日期：2009-12-01 00:00:00

abstract：:Hypercholesterolemia (HC) induces alterations in systemic vascular reactivity, which can manifest as an attenuated endothelium-dependent relaxation, partly consequent to an impairment in nitric oxide (NO) activity. To determine whether experimental HC has a similar effect on renal vascular function, renal artery segme...

journal_title：Atherosclerosis

authors： Stulak JM,Lerman A,Caccitolo JA,Wilson SH,Romero JC,Schaff HV,Rodriguez Porcel M,Lerman LO

更新日期：2001-01-01 00:00:00