Abstract：
:The purpose of this study was to devise a method for the tensile testing of the organic component of demineralised bone. It was hoped that the method could be applied to determine whether an observed reduction in the strength of bone in copper-deficient rats could be attributed to a reduction in the cross-linking of collagen. Tensile testing of a fully demineralised specimen proved impossible to perform because of the difficulty in gripping the material, which tended to slide out of its holding clamps. The technique devised involved the demineralisation of only the diaphysis of the bone, leaving the bone ends intact. This enabled the bone to be gripped firmly at both ends in an Instron tensile testing machine. Elongation under loading of the demineralised diaphysis was measured by the Instron and a video recording was made of the elongation of the central portion. The strain was found to be uniform. Tensile strength was found to correlate with copper levels in the liver (r = 0.54, p < 0.05), although no significant differences were found between the strength, the stiffness, or the strain to failure for bone from the copper-deficient animals and bone from the normal controls. The test method itself should be useful in other studies in which the tensile properties of the organic phase of bone need to be measured.
journal_name
J Biomechjournal_title
Journal of biomechanicsauthors
Jonas J,Burns J,Abel EW,Cresswell MJ,Strain JJ,Paterson CRdoi
10.1016/0021-9290(93)90365-lsubject
Has Abstractpub_date
1993-03-01 00:00:00pages
271-6issue
3eissn
0021-9290issn
1873-2380pii
0021-9290(93)90365-Ljournal_volume
26pub_type
杂志文章abstract：:The relationship between the structure of bone on the microscopic level and its mechanical properties was investigated by comparing bovine cortical bone of two microstructural types. Measurements of elastic properties were made in three orthogonal directions on specimens of plexiform and Haversian bone, taken from the...
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pub_type： 临床试验,杂志文章
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更新日期：2004-09-01 00:00:00
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更新日期：2000-07-01 00:00:00
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journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2008.11.003
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journal_title：Journal of biomechanics
pub_type： 杂志文章
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pub_type： 杂志文章
doi：10.1016/0021-9290(95)00086-0
更新日期：1996-05-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.jbiomech.2013.04.005
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pub_type： 杂志文章
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更新日期：2019-02-14 00:00:00
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journal_title：Journal of biomechanics
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更新日期：1996-11-01 00:00:00
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journal_title：Journal of biomechanics
pub_type： 杂志文章
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更新日期：1983-01-01 00:00:00
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abstract：:Patient specific quantitative CT (QCT) imaging data together with the finite element (FE) method may provide an accurate prediction of a patient's femoral strength and fracture risk. Although numerous FE models investigating femoral fracture strength have been published, there is little consent on the effect of bounda...
journal_title：Journal of biomechanics
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