Abstract：
:Patient specific quantitative CT (QCT) imaging data together with the finite element (FE) method may provide an accurate prediction of a patient's femoral strength and fracture risk. Although numerous FE models investigating femoral fracture strength have been published, there is little consent on the effect of boundary conditions, dynamic loading and hydraulic strengthening due to intra-medullary pressure on the predicted fracture strength. We developed a QCT-derived FE model of a proximal femur that included node-specific modulus assigned based on the local bone density. The effect of three commonly used boundary conditions published in literature were investigated by comparing the resulting strain field due to an applied fracture load. The models were also augmented with viscoelastic material properties and subject to a realistic impact load profile to determine the effect of dynamic loads on the strain field. Finally, the effect of hydraulic strengthening was investigated by including node specific permeability and performing a coupled pore diffusion and stress analysis of the FE model. Results showed that all boundary conditions yield the same strain field patterns, but peak strains were 22% lower and fracture load was 18% higher when loaded at the greater trochanter than when loaded at the femoral head. Comparison of the dynamic models showed that material viscoelasticity was important, but inertial effects (vibration and shock) were not. Finally, pore pressure changes did not cause significant hydraulic strengthening of bone under fall impact loading.
journal_name
J Biomechjournal_title
Journal of biomechanicsauthors
Haider IT,Speirs AD,Frei Hdoi
10.1016/j.jbiomech.2013.07.004subject
Has Abstractpub_date
2013-09-03 00:00:00pages
2115-21issue
13eissn
0021-9290issn
1873-2380pii
S0021-9290(13)00312-6journal_volume
46pub_type
杂志文章abstract：:The flow of cerebrospinal fluid (CSF) in a patient-specific model of the subarachnoid space in a Chiari I patient was investigated using numerical simulations. The pulsating CSF flow was modeled using a time-varying velocity pulse based on peak velocity measurements (diastole and systole) derived from a selection of p...
journal_title：Journal of biomechanics
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abstract：:Previous studies evaluated 3D human jaw movements using kinematic analysis systems during mouth opening, but information on the reliability of such measurements is still scarce. The purpose of this study was to analyze within- and between-session reliabilities, inter-rater reliability, standard error of measurement (S...
journal_title：Journal of biomechanics
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journal_title：Journal of biomechanics
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journal_title：Journal of biomechanics
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abstract：:Which of the elementary components (hydroxyapatite (HA) crystals, collagen, non-collagenous organic matter, water) do significantly contribute to the ultrastructural elastic stiffness magnitude and anisotropy of mineralized tissues; and how, i.e. through which shapes and assemblages (which micromechanical morphology)?...
journal_title：Journal of biomechanics
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更新日期：2002-09-01 00:00:00
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journal_title：Journal of biomechanics
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journal_title：Journal of biomechanics
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更新日期：2016-02-08 00:00:00
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journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(99)00100-1
更新日期：1999-10-01 00:00:00
abstract：:Foot mobility commonly contributes to injury via altered motion of the lower extremities. However, there is a lack of understanding of sensitive kinetic changes with flat foot. The purpose of this study was to investigate the threshold that best distinguishes between participants with and without flat foot. The kineti...
journal_title：Journal of biomechanics
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abstract：:The ability to quantitatively measure stability is essential to ensuring the safety of locomoting systems. While the response to perturbation directly reflects the stability of a motion, this experimental method puts human subjects at risk. Unfortunately, existing indirect methods for estimating stability from unpertu...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2018.02.022
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journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(96)00038-3
更新日期：1996-10-01 00:00:00
abstract：:Platelet activation under blood flow is thought to be critically dependent on the autologous secretion of soluble platelet agonists (chemical activators) such as ADP and thromboxane. However, recent evidence challenging this model suggests that platelet activation can occur independent of soluble agonist signalling, i...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2011.02.006
更新日期：2011-04-07 00:00:00
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journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2003.07.001
更新日期：2004-03-01 00:00:00
abstract：:The majority of fall-related accidents are during stair ambulation-occurring commonly at the top and bottom stairs of each flight, locations in which individuals are transitioning to stairs. Little is known about how individuals adjust their biomechanics in anticipation of walking-stair transitions. We identified the ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2015.12.041
更新日期：2016-02-29 00:00:00
abstract：:To better protect soldiers from blast threat, that principally affect air-filled organs such a lung, it is necessary to develop an adapted injury criterion and, prior to this, to evaluate the response of a biological model against that threat. The objective of this study is to provide some robust data to quantify the ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2017.10.012
更新日期：2017-12-08 00:00:00
abstract：:The aim of this study was to evaluate if there are sex differences in postures of upper arm, upper back, head and neck after muscle fatigue induced by a simulated work task, requiring upper arm movements performed above shoulder level. Nineteen females and 18 males were evaluated. Upper arm elevation, upper back, head...
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journal_title：Journal of biomechanics
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journal_title：Journal of biomechanics
pub_type： 杂志文章
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更新日期：2017-10-03 00:00:00
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journal_title：Journal of biomechanics
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doi：10.1016/j.jbiomech.2006.09.014
更新日期：2007-01-01 00:00:00
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journal_title：Journal of biomechanics
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doi：10.1016/j.jbiomech.2009.03.050
更新日期：2009-07-22 00:00:00
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journal_title：Journal of biomechanics
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journal_title：Journal of biomechanics
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更新日期：2013-03-15 00:00:00
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journal_title：Journal of biomechanics
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更新日期：2016-03-21 00:00:00
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journal_title：Journal of biomechanics
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doi：10.1016/j.jbiomech.2007.02.021
更新日期：2007-01-01 00:00:00
abstract：:High-resolution architecture-based finite element models are commonly used for characterizing the mechanical behavior of cancellous bone. The vast majority of studies use homogeneous material properties to model trabecular tissue. The objectives of this study were to demonstrate that inhomogeneous finite element model...
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更新日期：2004-05-01 00:00:00
