Abstract:
:Which of the elementary components (hydroxyapatite (HA) crystals, collagen, non-collagenous organic matter, water) do significantly contribute to the ultrastructural elastic stiffness magnitude and anisotropy of mineralized tissues; and how, i.e. through which shapes and assemblages (which micromechanical morphology)? We suggest answers to these questions by analyzing stiffness-volume fraction relationships of wet and dry tissue specimens in the framework of strain energy considerations. Radial stiffness values of both isotropic and anisotropic tissues are found to depend linearly to quadratically on only the mineral volume fraction. This suggests the isotropic contribution of HA to the ultrastructural stiffness. An energy-based analysis of the difference between the axial and radial stiffness values of anisotropic, collagen-rich tissues allows us to assess the collagen elasticity contribution, which is found to depend linearly on the extra-collagenous mineral concentration. These results suggest that collagen and hydroxyapatite are the elementary components governing the ultrastructural elastic stiffness magnitude and anisotropy of bone and mineralized tendons. The elastic stiffness of water and non-collagenous organic matter does not play a significant role. As for the morphological issue, we suggest that mineralized tissues are isotropic open crystal foams; and that these foams are reinforced unidirectionally by collagen molecules which are mechanically activated through tight links between these molecules and HA-crystals. The HA crystals are mechanically activated through stretching and bending in long bone tissues, they are predominantly stretched in mineralized tendons, and bent in hyperpycnotic tissues.
journal_name
J Biomechjournal_title
Journal of biomechanicsauthors
Hellmich Ch,Ulm FJdoi
10.1016/s0021-9290(02)00080-5keywords:
subject
Has Abstractpub_date
2002-09-01 00:00:00pages
1199-1212issue
9eissn
0021-9290issn
1873-2380pii
S0021929002000805journal_volume
35pub_type
杂志文章abstract::In quadrupeds, there have been limited comparisons of gait timing events detection (e.g., paw contact, PC and paw-off, PO) determined from kinematics and forceplates. The goal of this study was to investigate the effect of different slopes (0, -27, +27°), recovery times after ankle extensor nerve injury and repair (2,...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2012.03.013
更新日期:2012-05-11 00:00:00
abstract::Rubin et al. [J. Biomechanics 23, 43-54 (1990)] proposed that high frequency bone strains in the 15-30 Hz range might have significant influence on the morphological adaptation of bone tissue. We sought to further their findings by determining the magnitude of high frequency strains during various activities. We measu...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(95)80005-0
更新日期:1995-01-01 00:00:00
abstract::Cancellous bone architecture and mechanics are intimately related. The trabecular architecture of cancellous bone is considered determined by its mechanical environment (Wolff's law), and the mechanical properties of cancellous bone are inversely determined by the trabecular architecture and material properties. Much ...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/s0021-9290(96)00177-7
更新日期:1997-05-01 00:00:00
abstract::The second part of this study of the six axes of head motion caused by translational seat vibration is concerned with the effect of fore-and-aft (x-axis) and lateral (y-axis) seat vibration. Seat-to-head transmissibilities have been determined at frequencies up to 16 Hz for each of the three translational and three ro...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(88)90170-4
更新日期:1988-01-01 00:00:00
abstract::Accurate knowledge of extraocular muscle (EOM) tension is important for the diagnosis of and surgical planning for strabismus, such as choosing which eye to operate or determining the amount of muscle displacement. Previous evaluations of passive EOM tension have relied extensively on the experience and skill of ophth...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2020.109955
更新日期:2020-08-26 00:00:00
abstract::In this study, a new radiostereometric analysis (RSA) calibration cage was developed with the aim of improving the accuracy and precision of RSA. This development consisted of three steps: a numerical simulation technique was first used to design the new cage; a synthetic imaging method was then implemented to predict...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2007.11.012
更新日期:2008-01-01 00:00:00
abstract::The dynamics of arterial wall remodeling was studied on the basis of a phenomenological mathematical model. Sustained hypertension was simulated by a step increase in blood pressure. Remodeling rate equations were postulated for the evolution of the geometrical dimensions that characterize the zero stress state of the...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(95)00108-5
更新日期:1996-05-01 00:00:00
abstract::The ability to limit the trunk flexion associated with an anteriorly directed trip is a determinant of successful recovery of recovering postural stability and is subservient to rapidly detecting and correcting the imposed trunk flexion in the available time. This experiment tested the hypothesis that subjects demonst...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(95)00142-5
更新日期:1996-06-01 00:00:00
abstract::The problem of blood flow through stenoses is solved using the incompressible generalized Newtonian model. The Herschel-Bulkley, Bingham and power-law fluids are incorporated. The geometry corresponds to a rigid circular tube with a partial occlusion. Calculations are performed by a Galerkin finite-element method. For...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(95)00151-4
更新日期:1996-07-01 00:00:00
abstract::Surface EMG was recorded in four subjects on three different occasions from the three parts of the deltoid, the clavicular part of the pectoralis major and from the infraspinatus muscles at different angles of abduction, in the frontal and scapular plane. The integrated EMG was related to the maximum values found for ...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(85)90037-5
更新日期:1985-01-01 00:00:00
abstract::The healing of wounds is a complex process and the contraction of the resulting scar can have a negative impact on the neighbouring skin. A finite element model of skin simulating the contraction of a scar and deformation of the surrounding skin is presented. The skin is represented by an orthotropic-viscoelastic cons...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2008.02.024
更新日期:2008-01-01 00:00:00
abstract::We evaluated whether lumped-parameter non-linear viscoelastic models of human fingertip tissue can describe fingertip force-displacement characteristics during a range of rapid, dynamic tapping tasks. Eight human subjects tapped with their index finger on the surface of a rigid load cell while an optical system tracke...
journal_title:Journal of biomechanics
pub_type: 临床试验,杂志文章
doi:10.1016/s0021-9290(02)00438-4
更新日期:2003-04-01 00:00:00
abstract::The contact nature of American football has made head acceleration exposure a concern. We aimed to quantify the head kinematics associated with direct helmet contact and inertial head loading events in collegiate-level American football. A cohort of collegiate-level players were equipped with instrumented mouthguards ...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2020.109969
更新日期:2020-09-18 00:00:00
abstract::Maxillary expansion treatment is a commonly used procedure by orthodontists to widen a patient's upper jaw. As this is typically performed in adolescent patients, the midpalatal suture, connective tissue adjoining the two maxilla halves, remains unfused. Studies that have investigated patient response to expansion tre...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2013.04.011
更新日期:2013-06-21 00:00:00
abstract::Several motion capture methods exist for predicting hip joint centers (HJC). These methods include regression models, functional joints, and projections from greater trochanters. While regression and functional methods have been compared to imaging techniques, the TROCH method has not been previously validated. The pu...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2016.06.013
更新日期:2016-09-06 00:00:00
abstract::A biomechanical model of the human thorax was constructed to investigate how asymmetric growth of the thorax might initiate spinal lateral curvature and axial rotation as seen in scoliosis deformities. Geometric data specifying nodal points of the model were taken from stereo-radiographs of an adolescent subject. An i...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(90)90051-4
更新日期:1990-01-01 00:00:00
abstract::Current neck injury criteria are based on structural failure of the spinal (vertebral) column without consideration of injury to the spinal cord. Since one of the primary functions of the vertebral column is to protect the cord, it stands to reason that a more refined measure of neck injury threshold would be the onse...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2012.11.012
更新日期:2013-02-22 00:00:00
abstract::This work is a novel attempt to incorporate computational fluid dynamics (CFD) techniques in the analysis of hemodynamic parameters of Moyamoya disease (MMD). Highly prevalent in Asian countries, MMD is characterised by progressive occlusion of the intracranial Internal Carotid Arteries (ICA). We intend to identify a ...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2014.11.029
更新日期:2015-01-21 00:00:00
abstract::It is well accepted that the steady-state isometric force following active stretching of a muscle is greater than the steady-state isometric force obtained in a purely isometric contraction at the same length. This property of skeletal muscle has been called residual force enhancement (FE). Despite decades of research...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2008.06.007
更新日期:2008-08-28 00:00:00
abstract::Anesthetized, carefully positioned, female, weanling, white-haired pigs were used to test the hypothesis that (1) interface pressure, the pressure between the skin and an external load, can be used to predict the interstitial fluid pressure over the wings of ilia and the last dorsal spinous process and (2) three-dimen...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(91)90322-e
更新日期:1991-01-01 00:00:00
abstract::A numerical-experimental approach has been developed to characterize heel-pad deformation at the material level. Left and right heels of 20 diabetic subjects and 20 nondiabetic subjects matched for age, gender and body mass index were indented using force-controlled ultrasound. Initial tissue thickness and deformation...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2005.03.007
更新日期:2006-01-01 00:00:00
abstract::The application of joint contact mechanics requires a precise configuration of the joint surfaces. B-Spline, and NURBS have been widely used to model joint surfaces, but because these formulations use a structured data set provided by a rectangular net first, then a grid, there is a limit to the accuracy of the models...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2004.01.009
更新日期:2004-10-01 00:00:00
abstract::The use of cadavers for orthopaedic biomechanics research is well established, but presents difficulties to researchers in terms of cost, biosafety, availability, and ease of use. High fidelity composite models of human bone have been developed for use in biomechanical studies. While several studies have utilized comp...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2015.12.050
更新日期:2016-02-29 00:00:00
abstract::To know the contributions of blood pressure induced stress to the progression of atherosclerosis and the rupture of atheroma, cross-sectional distributions of stresses in atherosclerotic walls were calculated by finite element method, using stress-strain data of aortic walls and atherosclerotic plaques obtained from h...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/s0021-9290(96)00185-6
更新日期:1997-06-01 00:00:00
abstract::Side-cutting is commonly used to evaluate knee joint kinematics and kinetics in the context of anterior cruciate ligament injury risk. Many existing side-cutting studies fail to clearly define the orientation of the femoral frame and the knee axis, making comparisons between studies difficult. A femoral frame construc...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2012.05.017
更新日期:2012-07-26 00:00:00
abstract::We studied stress fiber orientation under a wide range of uniaxial cyclic deformations. We devised and validated a hypothesis consisting of two parts, as follows: (1) a stress fiber aligns to avoid a mechanical stimulus in the fiber direction under cyclic deformation. This means that, among all allowable directions, a...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/s0021-9290(00)00114-7
更新日期:2000-11-01 00:00:00
abstract::Little information is available on the direction-dependency of shear behavior in mandibular condylar cartilage. Therefore, we tested the hypothesis that such a dependency of the dynamic shear properties is present in mandibular condylar cartilage. From each of 17 condyles, two cartilage-bone plugs were dissected and t...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2007.12.012
更新日期:2008-01-01 00:00:00
abstract::The purpose of this paper is to investigate the theoretical basis for the pressure-distension behavior of the urinary bladder. A finite strain theory is developed for hollow spherical structures and it is shown that the Treloar model is a good prototype only for rubber balloons. The pressure-extension ratio relationsh...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(83)90055-6
更新日期:1983-01-01 00:00:00
abstract::Bone is subjected in vivo to both high amplitude, low frequency strain, incurred by locomotion, and to low amplitude, broad frequency strain. The biological effects of low amplitude, broad frequency strain are poorly understood. To evaluate the effects of low amplitude strains ranging in frequency from 0 to 50 Hz on o...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/s0021-9290(02)00245-2
更新日期:2003-01-01 00:00:00
abstract::We evaluated whether the use of cartilage thickness measurement would improve the ability of the arthroscopic indentation technique to estimate the intrinsic stiffness of articular cartilage. First, cartilage thickness and ultrasound reflection from the surface of bovine humeral head were registered in situ using a hi...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/s0021-9290(00)00189-5
更新日期:2001-02-01 00:00:00