Abstract:
:We evaluated whether the use of cartilage thickness measurement would improve the ability of the arthroscopic indentation technique to estimate the intrinsic stiffness of articular cartilage. First, cartilage thickness and ultrasound reflection from the surface of bovine humeral head were registered in situ using a high-frequency ultrasound probe. Subsequently, cartilage was indented in situ at the sites of the ultrasound measurements using arthroscopic instruments with plane-ended and spherical-ended indenters. Finally, full-thickness cartilage disks (n=30) were extracted from the indented sites (thickness=799-1654microm) and the equilibrium Young's modulus was determined with a material testing device in unconfined compression geometry. We applied analytical and numerical indentation models for the theoretical correction of experimental indentation measurements. An aspect-ratio (the ratio of indenter radius to cartilage thickness) correction improved the correlation of the indenter force with the equilibrium Young's modulus from r(2)=0.488 to r(2)=0.642-0.648 (n=30) for the plane-ended indenter (diameter=1.000mm, height=0.300mm) and from r(2)=0.654 to r(2)=0.684-0.692 (n=30) for the spherical-ended indenter (diameter=0.500mm, height=0.100mm), depending on the indentation model used for the correction. The linear correlation between the ultrasound reflection and the Young's modulus was r(2)=0.400 (n=30). These results suggest that with large indenters, knowledge of the cartilage thickness improves the reliability of the indentation measurements, especially in pathological situations where cartilage thickness may be significantly lower than normal. Ultrasound measurements also provide diagnostically important information about cartilage thickness as well as knowledge of the integrity of the superficial zone of cartilage.
journal_name
J Biomechjournal_title
Journal of biomechanicsauthors
Töyräs J,Lyyra-Laitinen T,Niinimäki M,Lindgren R,Nieminen MT,Kiviranta I,Jurvelin JSdoi
10.1016/s0021-9290(00)00189-5keywords:
subject
Has Abstractpub_date
2001-02-01 00:00:00pages
251-6issue
2eissn
0021-9290issn
1873-2380pii
S0021-9290(00)00189-5journal_volume
34pub_type
杂志文章abstract::The purpose of the study was to compare the effects of a feedback-controlled treadmill (FeedbackTM) to a traditional fixed-speed treadmill (FixedTM) on spatiotemporal gait means, variability, and dynamics. The study also examined inter-session reliability when using the FeedbackTM. Ten young adults walked on the Feedb...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2018.11.051
更新日期:2019-01-23 00:00:00
abstract::The anatomy of the distal femur has a predominant influence on the mechanics of both patello- and tibio-femoral joints. Especially, the morphological degeneration of the trochlear region dramatically affects the overall knee biomechanics and, from a clinical point of view, the staging of such a degeneration is fundame...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2019.07.008
更新日期:2019-09-20 00:00:00
abstract::This article describes a method to simulate fusion of morselized cancellous bone. The morselized cancellous bone is mixed with an epoxy adhesive, in empirically determined proportions. The mixture is then impacted into a construct. When the epoxy cures, the morselized material fuses into a cohesive, contiguous structu...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/s0021-9290(01)00032-x
更新日期:2001-06-01 00:00:00
abstract::A biomechanical model of the human thorax was constructed to investigate how asymmetric growth of the thorax might initiate spinal lateral curvature and axial rotation as seen in scoliosis deformities. Geometric data specifying nodal points of the model were taken from stereo-radiographs of an adolescent subject. An i...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(90)90051-4
更新日期:1990-01-01 00:00:00
abstract::Prolonged mechanical loading of soft tissues adjacent to bony prominences can lead to degeneration of muscle tissue, resulting in a condition termed pressure-related deep tissue injury. This type of deep pressure ulcers can develop into a severe wound, associated with problematic healing and a variable prognosis. Limi...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2008.09.016
更新日期:2008-12-05 00:00:00
abstract::Sphenodon, a lizard-like reptile, is the only living representative of a group that was once widespread at the time of the dinosaurs. Unique jaw mechanics incorporate crushing and shearing motions to breakdown food, but during this process excessive loading could cause damage to the jaw joints and teeth. In mammals li...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2010.08.001
更新日期:2010-12-01 00:00:00
abstract::A continuous wave technique is described for measuring the nine independent orthotropic elastic coefficients from a single cubic specimen. The side dimensions of this cubic specimen are on the order of 5 mm. Because of the small size of the specimen, the spatial resolution of material inhomogeneity using this techniqu...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(84)90029-0
更新日期:1984-01-01 00:00:00
abstract::Age-related changes in bone quality are mainly manifested in the reduced toughness. Since the post-yield deformation of bone is realized through microdamage formation (e.g., microcracking and diffuse damage), it is necessary to understand the mechanism of microdamage formation in bone in order to elucidate underlying ...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2005.01.009
更新日期:2006-01-01 00:00:00
abstract::We evaluated whether lumped-parameter non-linear viscoelastic models of human fingertip tissue can describe fingertip force-displacement characteristics during a range of rapid, dynamic tapping tasks. Eight human subjects tapped with their index finger on the surface of a rigid load cell while an optical system tracke...
journal_title:Journal of biomechanics
pub_type: 临床试验,杂志文章
doi:10.1016/s0021-9290(02)00438-4
更新日期:2003-04-01 00:00:00
abstract::This study aimed to compare the muscle activities of the lower limb during overground level running (LR) and uphill running (UR) by using a musculoskeletal model. Six male distance runners ran at three running speeds (slow: 3.3 m/s; medium: 4.2 m/s; and high: 5.0 m/s) on a level runway and a slope of 9.1% grade in whi...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2007.05.028
更新日期:2007-01-01 00:00:00
abstract::The effect of stress deprivation on the tendon tissue has been an important focus in the field of biomechanics. However, less is known about the in vivo effect of stress deprivation on fibroblast apoptosis as of yet. This study was conducted to test a hypothesis that complete stress deprivation of the patellar tendon ...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2009.07.027
更新日期:2009-11-13 00:00:00
abstract::This study investigated the plantar pressure distribution during gait on wooden surface with different slipperiness in the presence of contaminants. Fifteen Chinese males performed 10 walking trials on a 5-m wooden walkway wearing cloth shoe in four contaminated conditions (dry, sand, water, oil). A pressure insole sy...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2007.11.001
更新日期:2008-01-01 00:00:00
abstract::When balance is disturbed, location of the center of pressure (COP) contributes to a person's ability to recover from a perturbation. This study investigated COP control prior to first step lift-off (FSLO) during lateral perturbations in older non-fallers and fallers. 38 non-fallers and 16 fallers received lateral wai...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2015.02.012
更新日期:2015-04-13 00:00:00
abstract::Osteoporosis is a widely spread disease with severe consequences for patients and high costs for health care systems. The disease is characterised by a loss of bone mass which induces a loss of mechanical performance and structural integrity. It was found that transverse trabeculae are thinned and perforated while ver...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2009.06.017
更新日期:2009-09-18 00:00:00
abstract::Resident cells in the surface epitenon and internal compartment of flexor tendons are subjected to cyclic mechanical load as muscle contracts to move limbs or digits. Tendons are largely tensile load bearing tissues and are highly matrix intensive with nondividing cells providing maintenance functions. However, when a...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(95)00098-4
更新日期:1995-12-01 00:00:00
abstract::To date, the diagnosis of whiplash injuries has been very difficult and largely based on subjective, clinical assessment. The work by Winters and Peles Multiple Muscle Systems--Biomechanics and Movement Organization. Springer, New York (1990) suggests that the use of finite helical axes (FHAs) in the neck may provide ...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(94)90192-9
更新日期:1994-12-01 00:00:00
abstract::The aim of this study was to investigate the prevalence of abnormal knee biomechanical patterns in 40 patients with a modern TKA prosthesis, compared to 40 matched control participants when ascending and descending stairs. Fewer patients were able to ascend (65%) or descend stairs (53%) unassisted than controls (83%)....
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2014.03.026
更新日期:2014-06-03 00:00:00
abstract::In this paper we introduce the concept of the functional (or equivalent) geometry of the knee, which is an attempt to reduce the natural knee with its complex geometry, frictional resistance and deformable cartilage into a two-dimensional joint comprising rigid femur and tibia in frictionless contact. An apparatus and...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/s0021-9290(98)00141-9
更新日期:1999-01-01 00:00:00
abstract::An apparatus was designed for mechanical compression of cultured articular cartilage explants with acylindrical plain-ended loading head (diameter 2-5 mm) driven by a stepping motor. A load cell under the culture dish was applied for feedback regulation utilizing a microprocessor-based control unit. The operating prog...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(89)90232-7
更新日期:1989-01-01 00:00:00
abstract::Clinical decisions on interventions to improve function in children with cerebral palsy (CP) are based, in part, on hypothesized interactions amongst physical signs of CP and functional deficits. However, a knowledge gap exists regarding associations between spasticity and gait function. This study quantified associat...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2020.110218
更新日期:2021-01-16 00:00:00
abstract::In finite element (FE) models knee ligaments can represented either by a group of one-dimensional springs, or by three-dimensional continuum elements based on segmentations. Continuum models closer approximate the anatomy, and facilitate ligament wrapping, while spring models are computationally less expensive. The me...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2017.08.030
更新日期:2017-12-08 00:00:00
abstract::The Global Positioning System (GPS) offers many advantages over conventional methods for the determination of subject speed during biomechanical studies. Recent advances in GPS technology, in particular the implementation of the Wide-Angle Augmentation System and European Geostationary Navigation Overlay Service (WAAS...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2004.07.028
更新日期:2005-08-01 00:00:00
abstract::Abdominal aortic aneurysm (AAA) is a significant health problem. Current clinical rupture-risk relies primarily on the maximum diameter of the AAA and also growth rate. However, AAAs are a patient-specific problem and recently, numerical tools have been employed to estimate rupture-potential. Alternatively, experiment...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2012.05.004
更新日期:2012-06-26 00:00:00
abstract::The aim of this study was to investigate whether elimination of multifidus muscle in rats causes intervertebral disc (IVD) degeneration similar to that found after IVD lesion. Data were obtained from 36 male Wistar rats randomly assigned to one of three groups: (i) IVD lesion, in which the L4/L5 IVD was stabbed; (ii) ...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2018.01.004
更新日期:2018-03-21 00:00:00
abstract::Although micromechanical finite-element models are being increasingly used to help interpret the results of bio-mechanical tests, there has not yet been a systematic study of the numerical errors and uncertainties that occur with these methods. In this work, finite-element models of human L1 vertebra have been used to...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/s0021-9290(98)00108-0
更新日期:1998-10-01 00:00:00
abstract::Three-dimensional gait analysis (3D-GA) is commonly used to answer clinical questions of the form "which joints and what variables are most affected during when". When studying high-dimensional datasets, traditional dimension reduction methods (e.g. principal components analysis) require "data flattening", which may m...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2019.04.035
更新日期:2019-06-11 00:00:00
abstract::Healthy humans display a preference for walking at a stride frequency dependent on the inertial properties of their legs. Walking at preferred stride frequency (PSF) is predicted to maximize local dynamic stability, whereby sensitivity to intrinsic perturbations arising from natural variability inherent in biological ...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2013.10.012
更新日期:2014-01-03 00:00:00
abstract::An experimental compliance calibration method for measuring crack length in fracture toughness tests of cortical bone was developed. Calibration tests were conducted on twenty compact type fracture specimens machined from the mid-diaphysis of five pairs of equine third metacarpal bones. Specimens were oriented for cra...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/s0021-9290(02)00009-x
更新日期:2002-05-01 00:00:00
abstract::Stress, strain and modulus are regularly used to characterize material properties of tissue samples. However, when comparing results from different studies it is evident the reported material properties, particularly failure strains, vary hugely. The aim of our study was to characterize how and why specimen length and...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2010.04.040
更新日期:2010-08-26 00:00:00
abstract::In order to gain better understanding for rheology of an isolated red blood cell (RBC) and a group of multiple RBCs, new continuum models for describing mechanical properties of cellular structures of an RBC and inter-cellular interactions among multiple RBCs are developed. The viscous property of an RBC membrane, whi...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2015.11.027
更新日期:2016-07-26 00:00:00