Abstract：
:Osteoporosis is a widely spread disease with severe consequences for patients and high costs for health care systems. The disease is characterised by a loss of bone mass which induces a loss of mechanical performance and structural integrity. It was found that transverse trabeculae are thinned and perforated while vertical trabeculae stay intact. For understanding these phenomena and the mechanisms leading to fractures of trabecular bone due to osteoporosis, numerous researchers employ micro-finite element models. To avoid disadvantages in setting up classical finite element models, composite finite elements (CFE) can be used. The aim of the study is to test the potential of CFE. For that, a parameter study on numerical lattice samples with statistically simulated, simplified osteoporosis is performed. These samples are subjected to compression and shear loading. Results show that the biggest drop of compressive stiffness is reached for transverse isotropic structures losing 32% of the trabeculae (minus 89.8% stiffness). The biggest drop in shear stiffness is found for an isotropic structure also losing 32% of the trabeculae (minus 67.3% stiffness). The study indicates that losing trabeculae leads to a worse drop of macroscopic stiffness than thinning of trabeculae. The results further demonstrate the advantages of CFEs for simulating micro-structured samples.
journal_name
J Biomechjournal_title
Journal of biomechanicsauthors
Wolfram U,Schwen LO,Simon U,Rumpf M,Wilke HJdoi
10.1016/j.jbiomech.2009.06.017subject
Has Abstractpub_date
2009-09-18 00:00:00pages
2205-9issue
13eissn
0021-9290issn
1873-2380pii
S0021-9290(09)00340-6journal_volume
42pub_type
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